@article{UBHD-68734705, author={Abdul Pari, Ashik Ahmed and Singhal, Mahak and Augustin, Hellmut}, title={Emerging paradigms in metastasis research}, year={2021}, pages={1-12}, language={eng}, issn={1540-9538}, volume={218}, note={December 18 2020 ; Gesehen am 06.05.2021}, journal={Journal of experimental medicine}, doi={10.1084/jem.20190218}, } @article{UBHD-68735997, author={Abdul Pari, Ashik Ahmed and Singhal, Mahak and H{\"u}bers, Corinne and Mogler, Carolin and Schieb, Benjamin and Gampp, Anja and Gengenbacher, Nicolas and Reynolds, Louise E. and Terhardt, Dorothee and Géraud, Cyrill and Utikal, Jochen and Thomas, Markus and Goerdt, Sergij and Hodivala-Dilke, Kairbaan M. and Augustin, Hellmut and Felcht, Moritz}, title={Tumor cell-derived angiopoietin-2 promotes metastasis in melanoma}, year={2020}, pages={2586-2598}, language={eng}, issn={1538-7445}, volume={80}, number={12 vom: Juni}, note={Gesehen am 10.05.2021}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-19-2660}, } @article{UBHD-67580850, author={Adam, M. Gordian and Hammes, Hans-Peter and Augustin, Hellmut and Fischer, Andreas}, title={Synaptojanin-2 binding protein stabilizes the notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis}, year={2013}, pages={1206-1218}, language={eng}, issn={1524-4571}, volume={113}, number={11}, note={Gesehen am: 12.05.2014}, journal={Circulation research}, doi={10.1161/CIRCRESAHA.113.301686}, } @article{UBHD-69082915, author={Arseni, Lavinia and Sharma, Rakesh and Mack, Norman and Nagalla, Deepthi and Ohl, Sibylle and Hielscher, Thomas and Singhal, Mahak and Engel, Robert and Augustin, Hellmut and Sandhoff, Roger and Herold-Mende, Christel and Tews, Bj{\"o}rn and Lichter, Peter and Seiffert, Martina}, title={Sphingosine-1-phosphate recruits macrophages and microglia and induces a pro-tumorigenic phenotype that favors glioma progression}, year={2023}, pages={1-23}, language={eng}, issn={2072-6694}, volume={15}, note={Gesehen am 06.06.2023}, journal={Cancers}, doi={10.3390/cancers15020479}, } @article{UBHD-69028393, author={Augustin, Hellmut and Koh, Gou Young}, title={Antiangiogenesis: vessel regression, vessel normalization, or both?}, subtitle={Cancer research landmarks}, year={2022}, pages={15-17}, language={eng}, issn={1538-7445}, volume={82}, number={1}, note={Gesehen am 31.01.2023}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-21-3515}, } @article{UBHD-68275449, author={Augustin, Hellmut and Koh, Gou Young}, title={Organotypic vasculature}, subtitle={from descriptive heterogeneity to functional pathophysiology}, year={2017}, pages={12 S.}, language={eng}, issn={1095-9203}, volume={357(2017}, note={Gesehen am 28.06.2018}, journal={Science}, doi={10.1126/science.aal2379}, } @article{UBHD-68251902, author={Augustin, Hellmut}, title={Regulation of angiogenesis and vascular homeostasis through the Angiopoietin/Tie system}, year={2012}, pages={307-308}, language={eng}, issn={1879-3649}, volume={56}, number={5}, note={Gesehen am 14.05.2018}, journal={Vascular pharmacology}, doi={10.1016/j.vph.2011.08.008}, } @article{UBHD-69274517, author={Augustin, Hellmut and Koh, Gou Young}, title={A systems view of the vascular endothelium in health and disease}, year={2024}, pages={4833-4858}, language={eng}, issn={1097-4172}, volume={187}, number={18}, note={Online verf{\"u}gbar: 5. September 2024, Artikelversion: 5. September 2024 ; Gesehen am 18.11.2024}, journal={Cell}, doi={10.1016/j.cell.2024.07.012}, } @article{UBHD-68992671, author={Augustin, Hellmut and Kipnis, Jonathan}, title={Vascular rejuvenation is geroprotective}, subtitle={vascular endothelial growth factor : a extends life span and health span in mice}, year={2021}, pages={490-491}, language={eng}, issn={1095-9203}, volume={373}, number={6554 vom: Juli}, note={Published July 30, 2021 ; Gesehen am 05.12.2022}, journal={Science}, doi={10.1126/science.abj8674}, } @article{UBHD-68497923, author={Bauer, Corinne and Abdul Pari, Ashik Ahmed and Umansky, Viktor and Utikal, Jochen and Boukamp, Petra and Augustin, Hellmut and Goerdt, Sergij and Géraud, Cyrill and Felcht, Moritz}, title={T-lymphocyte profiles differ between keratoacanthomas and invasive squamous cell carcinomas of the human skin}, year={2018}, pages={1147-1157}, language={eng}, issn={1432-0851}, volume={67}, number={7}, note={Gesehen am 05.03.2020}, journal={Cancer immunology immunotherapy}, doi={10.1007/s00262-018-2171-7}, } @article{UBHD-67693540, author={Benest, Andrew V. and Savant, Soniya and Augustin, Hellmut}, title={Angiopoietin-2 is critical for cytokine-induced vascular leakage}, year={2013}, pages={e70459}, language={eng}, issn={1932-6203}, volume={8}, number={8}, note={Gesehen am: 28.10.2014}, journal={PLOS ONE}, doi={10.1371/journal.pone.0070459}, } @article{UBHD-67443372, author={Bieback, Karen and Elvers-Hornung, Susanne and Gloe, Torsten and Kl{\"u}ter, Harald and Augustin, Hellmut}, title={Recruitment of human cord blood-derived endothelial colony-forming cells to sites of tumor angiogenesis}, year={2013}, pages={726-739}, language={eng}, issn={1477-2566}, volume={15}, number={6}, note={Gesehen am: 10.07.2013}, journal={Cytotherapy}, doi={10.1016/j.jcyt.2013.01.215}, } @article{UBHD-68098923, author={B{\"o}ck, Barbara and Schmitt, Clemens Alexander and Augustin, Hellmut}, title={Mouse models of human cancer}, subtitle={Zusatztitel}, year={2014}, pages={4671-4675}, language={eng}, issn={1538-7445}, volume={74}, number={17}, note={Gesehen am: 22.03.2017}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-14-1424}, } @article{UBHD-68345608, author={Botla, Sandeep Kumar and Savant, Soniya and Gaida, Matthias and B{\"u}chler, Markus W. and Strobel, Oliver and Hackert, Thilo and Giese, Nathalia and Augustin, Hellmut}, title={Early epigenetic downregulation of microRNA-192 expression promotes pancreatic cancer progression}, year={2016}, pages={4149-4159}, language={eng}, issn={1538-7445}, volume={76}, number={14}, note={Gesehen am 09.01.2019}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-15-0390}, } @article{UBHD-68265335, author={Breitkopf-Heinlein, Katja and Meyer, Christoph and K{\"o}nig, Courtney and Gaitantzi, Haristi and Cai, Chen and Li, Qi and Valous, Nektarios A. and Klingm{\"u}ller, Ursula and Ilkavets, Iryna and Wieland, Matthias and Ebert, Matthias and Augustin, Hellmut and Dooley, Steven}, title={BMP-9 interferes with liver regeneration and promotes liver fibrosis}, year={2017}, pages={939-954}, language={eng}, issn={1468-3288}, volume={66}, number={5}, note={Gesehen am 26.06.2018}, journal={Gut}, doi={10.1136/gutjnl-2016-313314}, } @article{UBHD-69049302, author={Br{\"u}tsch, René Michael and Liebler, Sven Stefan and W{\"u}stehube-Lausch, Joycelyn and Bartol, Arne and Herberich, Stefanie E. and Adam, M. Gordian and Telzerow, Anja and Augustin, Hellmut and Fischer, Andreas}, title={Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis}, year={2010}, pages={592-601}, language={eng}, issn={1524-4571}, volume={107}, number={5}, note={Gesehen am 08.03.2023}, journal={Circulation research}, doi={10.1161/CIRCRESAHA.110.217257}, } @article{UBHD-68773401, author={Cifarelli, Vincenza and Appak-Baskoy, Sila and Peche, Vivek S. and Kluzak, Andrew and Shew, Trevor and Narendran, Ramkumar and Pietka, Kathryn M. and Cella, Marina and Walls, Curtis W. and Czepielewski, Rafael and Ivanov, Stoyan and Randolph, Gwendalyn J. and Augustin, Hellmut and Abumrad, Nada A.}, title={Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells}, year={2021}, pages={1-15}, language={eng}, issn={2041-1723}, volume={12}, number={Artikel-ID 3350}, note={Gesehen am 24.08.2021}, journal={Nature Communications}, doi={10.1038/s41467-021-23808-3}, } @article{UBHD-68201852, author={Demolli, Shemsi and Savant, Soniya and Hecker, Markus and Augustin, Hellmut}, title={MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of angiopoietin 2}, year={2015}, pages={111-119}, language={eng}, issn={1095-8584}, volume={88}, note={Gesehen am 14.12.2017}, journal={Journal of molecular and cellular cardiology}, doi={10.1016/j.yjmcc.2015.10.009}, } @article{UBHD-67338328, author={Dieterich, Lothar C. and Augustin, Hellmut}, title={Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGF beta 2 in vascular abnormalization}, year={2012}, pages={378-390}, language={eng}, issn={0022-3417}, volume={228}, number={3}, journal={The journal of pathology}, } @article{UBHD-68314285, author={Fantin, Alessandro and Augustin, Hellmut}, title={VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation}, year={2017}, pages={1049-1064}, language={eng}, issn={1540-9538}, volume={214}, number={4}, note={Gesehen am 11.10.2018}, journal={Journal of experimental medicine}, doi={10.1084/jem.20160311}, } @article{UBHD-68328728, author={Felcht, Moritz and Vettel, Christiane and Kutschera, Simone and Appak, Sila and Wieland, Thomas and Goerdt, Sergij and Augustin, Hellmut}, title={Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling}, year={2012}, pages={1991-2005}, language={eng}, issn={1558-8238}, volume={122}, number={6}, note={Gesehen am 15.11.2018}, journal={The journal of clinical investigation}, doi={10.1172/JCI58832}, } @article{UBHD-67694904, author={Fischer, Silvia and Augustin, Hellmut}, title={Extracellular RNA liberates tumor necrosis factor-alpha to promote tumor cell trafficking and progression}, year={2013}, pages={5080-5089}, language={eng}, issn={1538-7445}, volume={73}, number={16}, note={Gesehen am: 30.10.2014}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-12-4657}, } @article{UBHD-68497965, author={Freire Valls, Aida and Knipper, Karl and Giannakouri, Evangelia and Sarachaga, Víctor and Hinterkopf, Sascha and W{\"u}hrl, Michael and Shen, Ying and Radhakrishnan, Praveen and Klose, Johannes and Ulrich, Alexis and Schneider, Martin and Augustin, Hellmut and Ruiz de Almodóvar, Carmen and Schmidt, Thomas}, title={VEGFR1+ metastasis-associated macrophages contribute to metastatic angiogenesis and influence colorectal cancer patient outcome}, year={2019}, pages={5674-5685}, language={eng}, issn={1557-3265}, volume={25}, number={18}, note={Gesehen am 05.03.2020 ; Das Zeichen "+" ist im Titel hochgestellt}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-18-2123}, } @article{UBHD-68261250, author={Galuschka, Claudia and Augustin, Hellmut}, title={Models in translational oncology}, subtitle={a public resource database for preclinical cancer research}, year={2017}, pages={2557-2563}, language={eng}, issn={1538-7445}, volume={77}, number={10}, note={Published May 2017 ; Gesehen am 14.06.2018}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-16-3099}, } @article{UBHD-68253007, author={Gengenbacher, Nicolas and Singhal, Mahak and Augustin, Hellmut}, title={Preclinical mouse solid tumour models}, subtitle={status quo, challenges and perspectives}, year={2017}, pages={751-765}, language={eng}, issn={1474-1768}, volume={17}, number={12}, note={Gesehen am 17.05.2018}, journal={Nature reviews}, doi={10.1038/nrc.2017.92}, } @article{UBHD-68732670, author={Gengenbacher, Nicolas and Singhal, Mahak and Mogler, Carolin and Hai, Ling and Milde, Laura and Abdul Pari, Ashik Ahmed and Besemfelder, Eva and Fricke, Claudine and Baumann, Daniel and Gehrs, Stephanie and Utikal, Jochen and Felcht, Moritz and Hu, Junhao and Schlesner, Matthias and Offringa, Rienk and Chintharlapalli, Sudhakar R. and Augustin, Hellmut}, title={Timed Ang2-targeted therapy identifies the Angiopoietin-tie pathway as key regulator of fatal lymphogenous metastasis}, year={2021}, pages={424-445}, language={eng}, issn={2159-8290}, volume={11}, number={2}, note={Gesehen am 03.05.2021 ; Published online first October 26, 2020}, journal={Cancer discovery}, doi={10.1158/2159-8290.CD-20-0122}, } @article{UBHD-67388099, author={Gerald, Damien and Augustin, Hellmut}, title={Angiopoietin-2}, subtitle={an attractive target for improved antiangiogenic tumor therapy}, year={2013}, pages={1649-1657}, language={eng}, issn={0008-5472}, volume={73}, number={6}, journal={Cancer research}, } @article{UBHD-67660550, author={Géraud, Cyrill and Weiß, Christel and Damm, Friederike and Schmieder, Astrid and Schirmacher, Peter and Augustin, Hellmut and Goerdt, Sergij and Mogler, Carolin and Evdokimov, Konstantin and Lu, Shun and Schledzewski, Kai and Reiners-Koch, Philipp-Sebastian and Breuhahn, Kai and Longerich, Thomas and Marx, Alexander}, title={Endothelial transdifferentiation in hepatocellular carcinoma}, subtitle={loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival}, year={2013}, pages={1428-1440}, language={eng}, issn={1478-3231}, volume={33}, number={9}, note={Gesehen am: 13.08.2014}, journal={Liver international}, doi={10.1111/liv.12262}, } @article{UBHD-68249249, author={Géraud, Cyrill and Reiners-Koch, Philipp-Sebastian and Zierow, Johanna and Busch, Katrin and Olsavszky, Victor and Leibing, Thomas and Demory, Alexandra and Ulbrich, Friederike and Diett, Miriam and Singh, Sandhya and Sticht, Carsten and Breitkopf-Heinlein, Katja and Rodewald, Hans-Reimer and Augustin, Hellmut and Schledzewski, Kai and Goerdt, Sergij}, title={GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis}, year={2017}, pages={1099-1114}, language={eng}, issn={1558-8238}, volume={127}, number={3}, note={Gesehen am 04.05.2018}, journal={The journal of clinical investigation}, doi={10.1172/JCI90086}, } @article{UBHD-68249236, author={Géraud, Cyrill and Evdokimov, Konstantin and Straub, Beate Katharina and Ludwig-Peitsch, Wiebke and Demory, Alexandra and D{\"o}rflinger, Yvette and Schledzewski, Kai and Schmieder, Astrid and Schemmer, Peter and Augustin, Hellmut and Schirmacher, Peter and Goerdt, Sergij}, title={Unique cell type-specific junctional complexes in vascular endothelium of human and rat liver sinusoids}, year={2012}, pages={11 S.}, language={eng}, issn={1932-6203}, volume={7(2012}, note={Gesehen am 04.05.2018}, journal={PLOS ONE}, doi={10.1371/journal.pone.0034206}, } @article{UBHD-68720652, author={Groth, Christopher and Arpinati, Ludovica and Shaul, Merav E. and Winkler, Nina and Diester, Klara and Gengenbacher, Nicolas and Weber, Rebekka and Arkhypov, Ihor and Lasser, Samantha and Petrova, Vera and Augustin, Hellmut and Altevogt, Peter and Utikal, Jochen and Fridlender, Zvi G. and Umansky, Viktor}, title={Blocking migration of polymorphonuclear myeloid-derived suppressor cells inhibits mouse melanoma progression}, year={2021}, pages={1-20}, language={eng}, issn={2072-6694}, volume={13}, note={Gesehen am 07.04.2021}, journal={Cancers}, doi={10.3390/cancers13040726}, } @article{UBHD-68378577, author={Han, Sangyeul and Augustin, Hellmut}, title={Amelioration of sepsis by TIE2 activation-induced vascular protection}, year={2016}, pages={11 S.}, language={eng}, issn={1946-6242}, volume={8(2016}, note={Gesehen am 04.04.2019}, journal={Science translational medicine}, doi={10.1126/scitranslmed.aad9260}, } @article{UBHD-68301563, author={Hasanov, Zulfiyya and Kapel, Stephanie and Wieland, Matthias and Augustin, Hellmut}, title={Endosialin promotes atherosclerosis through phenotypic remodeling of vascular smooth muscle cells}, year={2017}, pages={495-505}, language={eng}, issn={1524-4636}, volume={37}, number={3}, note={Gesehen am 03.09.2018}, journal={Arteriosclerosis, thrombosis, and vascular biology}, doi={10.1161/ATVBAHA.116.308455}, } @article{UBHD-67375161, author={Hassel, David and Kroll, Jens and Augustin, Hellmut and Katus, Hugo}, title={MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling}, year={2012}, pages={1421-1433}, language={eng}, issn={0009-7330 and 0931-6876}, volume={111}, number={11}, journal={Circulation research}, } @article{UBHD-67507408, author={Hassel, David and Kroll, Jens and Augustin, Hellmut and Katus, Hugo}, title={MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling}, year={2012}, pages={1421-1433}, language={eng}, issn={1524-4571}, volume={111}, number={11}, journal={Circulation research}, doi={10.1161/CIRCRESAHA.112.279711}, } @article{UBHD-68212201, author={Heiss, Maximilian and Hecker, Markus and Augustin, Hellmut and Korff, Thomas}, title={Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro}, year={2015}, pages={3076-3084}, language={eng}, issn={1530-6860}, volume={29}, number={7}, note={Gesehen am 22.01.2018}, journal={The FASEB journal}, doi={10.1096/fj.14-267633}, } @article{UBHD-69066913, author={Helfrich, Iris and Scheffrahn, Inka and Bartling, S{\"o}nke and Weis, Joachim and von Felbert, Verena and Middleton, Mark and Kato, Masahi and Erg{\"u}n, S{\"u}leyman and Augustin, Hellmut and Schadendorf, Dirk}, title={Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma}, year={2010}, pages={491-503}, language={eng}, issn={1540-9538}, volume={207}, number={3 vom: M{\"a}rz}, note={Gesehen am 19.04.2023}, journal={Journal of experimental medicine}, doi={10.1084/jem.20091846}, } @article{UBHD-69069400, author={Héroult, Mélanie and Schaffner, Florence and Pfaff, Dennis and Prahst, Claudia and Kirmse, Robert and Kutschera, Simone and Riedel, Maria and Ludwig, Thomas and Vajkoczy, Peter and Graeser, Ralph and Augustin, Hellmut}, title={EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2}, year={2010}, pages={1297-1309}, language={eng}, issn={1557-3125}, volume={8}, number={10 vom: Okt.}, note={Gesehen am 26.04.2023}, journal={Molecular cancer research}, doi={10.1158/1541-7786.MCR-09-0453}, } @article{UBHD-68630906, author={Holm, Annegret Elisabeth and Heumann, Tina and Augustin, Hellmut}, title={Microvascular mural cell organotypic heterogeneity and functional plasticity}, year={2018}, pages={302-316}, language={eng}, issn={1879-3088}, volume={28}, number={4}, note={Gesehen am 25.08.2020}, journal={Trends in cell biology}, doi={10.1016/j.tcb.2017.12.002}, } @article{UBHD-68980994, author={H{\"u}bers, Corinne and Abdul Pari, Ashik Ahmed and Grieshober, Denise and Petkov, Martin and Schmidt, Alexander and Meßmer, Tatjana and Heyer, Christian Moritz and Sch{\"o}lch, Sebastian and Kapel, Stephanie and Gengenbacher, Nicolas and Singhal, Mahak and Schieb, Benjamin and Fricke, Claudine and Will, Rainer D. and Remans, Kim and Utikal, Jochen and Reißfelder, Christoph and Schlesner, Matthias and Hodivala-Dilke, Kairbaan M. and Kersten, Sander and Goerdt, Sergij and Augustin, Hellmut and Felcht, Moritz}, title={Primary tumor-derived systemic nANGPTL4 inhibits metastasis}, year={2022}, pages={1-24}, language={eng}, issn={1540-9538}, volume={220}, note={Gesehen am 02.11.2022}, journal={Journal of experimental medicine}, doi={10.1084/jem.20202595}, } @article{UBHD-68007610, author={Hu, Junhao and Mogler, Carolin and Augustin, Hellmut}, title={Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat}, year={2014}, pages={416-419}, language={eng}, issn={1095-9203}, volume={343}, number={6169}, note={Gesehen am: 14.07.2016}, journal={Science}, doi={10.1126/science.1244880}, } @article{UBHD-67358805, author={Im, Jae Hong and Augustin, Hellmut}, title={G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency}, year={2013}, pages={315-326}, language={eng}, issn={0020-7136}, volume={132}, number={2}, journal={International journal of cancer}, } @article{UBHD-68741888, author={Inverso, Donato and Shi, Jingjing and Lee, Ki Hong and Jakab, Moritz and Ben-Moshe, Shani and Kulkarni, Shubhada and Schneider, Martin and Wang, Guanxiong and Komeili, Marziyeh and Argos Vélez, Paula and Riedel, Maria and Spegg, Carleen and Ruppert, Thomas and Schaeffer-Reiss, Christine and Helm, Dominic and Singh, Indrabahadur and Boutros, Michael and Chintharlapalli, Sudhakar and Heikenwalder, Mathias and Itzkovitz, Shalev and Augustin, Hellmut}, title={A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver}, year={2021}, pages={1677-1693.e10}, language={eng}, issn={1878-1551}, volume={56}, number={11 vom: Juni}, note={Das PDF enth{\"a}lt zus{\"a}tzlich einen Anhang ; Gesehen am 28.05.2021}, journal={Developmental cell}, doi={10.1016/j.devcel.2021.05.001}, } @article{UBHD-68213577, author={Jabs, Markus and Lehmann, Lorenz and Sauer, Sven and Poschet, Gernot and Augustin, Hellmut and Gretz, Norbert and Hell, R{\"u}diger and Okun, J{\"u}rgen G. and Backs, Johannes and Nawroth, Peter Paul and Fischer, Andreas}, title={Inhibition of endothelial notch signaling impairs fatty acid transport and leads to metabolic and vascular remodeling of the adult heart}, year={2018}, pages={2592-2608}, language={eng}, issn={1524-4539}, volume={136}, number={24}, note={Originally published January 20, 2018 ; Gesehen am 13.06.2019}, journal={Circulation}, doi={10.1161/CIRCULATIONAHA.117.029733}, } @article{UBHD-69185971, author={Jakab, Moritz and Lee, Ki Hong and Uvarovskii, Alexey and Ovchinnikova, Svetlana and Kulkarni, Shubhada and Jakab, Sevinç and Rostalski, Till and Spegg, Carleen and Anders, Simon and Augustin, Hellmut}, title={Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency}, year={2024}, pages={32 S.}, language={eng}, issn={2662-1347}, volume={5}, note={Gesehen am 27.02.2024}, journal={Nature cancer}, doi={10.1038/s43018-023-00716-7}, } @article{UBHD-68918186, author={Jakab, Moritz and Rostalski, Till and Lee, Ki Hong and Mogler, Carolin and Augustin, Hellmut}, title={Tie2 receptor in tumor-infiltrating macrophages is dispensable for fumor angiogenesis and tumor relapse after chemotherapy}, year={2022}, pages={1353-1364}, language={eng}, issn={1538-7445}, volume={82}, number={7}, note={Gesehen am 13.05.2022}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-21-3181}, } @article{UBHD-68657972, author={Jakab, Moritz and Augustin, Hellmut}, title={Understanding angiodiversity}, subtitle={insights from single cell biology}, year={2020}, language={eng}, issn={1477-9129}, volume={147(2020}, note={Gesehen am 05.11.2020}, journal={Development}, doi={10.1242/dev.146621}, } @article{UBHD-67383108, author={Kaluza, David and Kroll, Jens and Augustin, Hellmut}, title={Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells}, year={2013}, pages={533-543}, language={eng}, issn={1079-5642}, volume={33}, number={3}, journal={Arteriosclerosis, thrombosis, and vascular biology}, } @article{UBHD-68739922, author={Kamiyama, Miki and Augustin, Hellmut}, title={Alternatively spliced form of angiopoietin-2 as a new vascular rheostat}, year={2021}, pages={35-37}, language={eng}, issn={1538-7445}, volume={81}, number={1}, note={Gesehen am 20.05.2021}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-20-3695}, } @article{UBHD-69085927, author={Karreman, Matthia A. and Bauer, Alexander T. and Solecki, Gergely and Bergmeister-Berghoff, Anna Sophie and Mayer, Chanté D. and Frey, Katharina and Hebach, Nils R. and Feinauer, Manuel and Schieber, Nicole L. and Tehranian, Cedric and Mercier, Luc and Singhal, Mahak and Venkataramani, Varun and Schubert, Marc C. and Hinze, Daniel and H{\"o}lzel, Michael and Helfrich, Iris and Schadendorf, Dirk and Schneider, Stefan W. and Westphal, Dana and Augustin, Hellmut and Goetz, Jacky G. and Schwab, Yannick and Wick, Wolfgang and Winkler, Frank}, title={Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization}, year={2023}, pages={1299-1314}, language={eng}, issn={1538-7445}, volume={83}, number={8 vom: Apr.}, note={Gesehen am 15.06.2023}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-22-3964}, } @article{UBHD-67550081, author={Kienast, Yvonne and Augustin, Hellmut}, title={Ang-2-VEGF-A crossmab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy}, year={2013}, pages={6730-6740}, language={eng}, issn={1557-3265}, volume={19}, number={24}, note={Gesehen am: 12.03.2014}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-13-0081}, } @article{UBHD-68442179, author={Kim, Kyun Hoo and Augustin, Hellmut}, title={Myocardial angiopoietin-1 controls atrial chamber morphogenesis by spatiotemporal degradation of cardiac jelly}, year={2018}, pages={2455-2466}, language={eng}, issn={2211-1247}, volume={23}, number={8}, note={Gesehen am 18.10.2019}, journal={Cell reports}, doi={10.1016/j.celrep.2018.04.080}, } @article{UBHD-68229398, author={Klose, Ralph Sebastian and Augustin, Hellmut and Fischer, Andreas}, title={Soluble Notch ligand and receptor peptides act antagonistically during angiogenesis}, year={2015}, pages={153-163}, language={eng}, issn={1755-3245}, volume={107}, number={1}, note={Gesehen am 12.03.2018}, journal={Cardiovascular research}, doi={10.1093/cvr/cvv151}, } @article{UBHD-69185533, author={Koh, Gou Young and Augustin, Hellmut and Campochiaro, Peter}, title={Viewpoints: Dual-blocking antibody against VEGF-A and angiopoietin-2 for treating vascular diseases of the eye}, subtitle={forum}, year={2022}, pages={347-349}, language={eng}, issn={1471-499X}, volume={28}, number={5 vom: Mai}, note={Online verf{\"u}gbar: 5 April 2022, Artikelversion: 28 April 2022 ; Gesehen am 26.02.2024}, journal={Trends in molecular medicine}, doi={10.1016/j.molmed.2022.03.004}, } @article{UBHD-68322677, author={Korff, Thomas and Nobiling, Rainer and Feldner, Anja and Augustin, Hellmut and Hecker, Markus}, title={Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin-2 from endothelial cells}, year={2012}, pages={510-518}, language={eng}, issn={1755-3245}, volume={94}, number={3}, note={Gesehen am 29.10.2018}, journal={Cardiovascular research}, doi={10.1093/cvr/cvs124}, } @article{UBHD-69132612, author={Korhonen, Emilia Anne and Murtom{\"a}ki, Aino and Jha, Sawan Kumar and Anisimov, Andrey and Pink, Anne and Zhang, Yan and Stritt, Simon and Liaqat, Inam and Stanczuk, Lukas and Alderfer, Laura and Sun, Zhiliang and Kapiainen, Emmi and Singh, Abhishek and Sultan, Ibrahim and Lantta, Anni and Lepp{\"a}nen, Veli-Matti and Eklund, Lauri and He, Yulong and Augustin, Hellmut and Vaahtomeri, Kari and Saharinen, Pipsa and M{\"a}kinen, Taija and Alitalo, Kari}, title={Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression}, year={2022}, pages={1-17}, language={eng}, issn={1558-8238}, volume={132}, note={Gesehen am 23.10.2023}, journal={The journal of clinical investigation}, doi={10.1172/JCI155478}, } @article{UBHD-68322687, author={Korn, Claudia and Augustin, Hellmut}, title={Born to die}, subtitle={blood vessel regression research coming of age}, year={2012}, pages={3063-3065}, language={eng}, issn={1524-4539}, volume={125}, number={25}, note={Gesehen am 29.10.2018}, journal={Circulation}, } @article{UBHD-67974523, author={Korn, Claudia and Wojtarowicz, Jessica and Boutros, Michael and Augustin, Hellmut and Augustin, Iris}, title={Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis}, year={2014}, pages={1757-1766}, language={eng}, issn={1477-9129}, volume={141}, number={8}, note={Gesehen am: 03.05.2016}, journal={Development}, doi={10.1242/dev.104422}, } @article{UBHD-68214437, author={Korn, Claudia and Augustin, Hellmut}, title={Mechanisms of vessel pruning and regression}, year={2015}, pages={5-17}, language={eng}, issn={1878-1551}, volume={34}, number={1}, note={Gesehen am 29.01.2018}, journal={Developmental cell}, doi={10.1016/j.devcel.2015.06.004}, } @article{UBHD-69129010, author={Kotsiliti, Elena and Leone, Valentina and Sch{\"u}hle, Svenja and Govaere, Olivier and Li, Hai and Wolf, Monika J. and Horvatic, Helena and Bierwirth, Sandra and Hundertmark, Jana and Inverso, Donato and Zizmare, Laimdota and Sarusi-Portuguez, Avital and Gupta, Revant and O’Connor, Tracy and Giannou, Anastasios D. and Shiri, Ahmad Mustafa and Schlesinger, Yehuda and Beccaria, Maria Garcia and Rennert, Charlotte and Pfister, Dominik and {\"O}llinger, Rupert and Gadjalova, Iana and Ramadori, Pierluigi and Rahbari, Mohammad and Rahbari, Nuh Nabi and Healy, Marc E. and Fernández Vaquero, Mirian and Yahoo, Neda and Janzen, Jakob and Singh, Indrabahadur and Fan, Chaofan and Liu, Xinyuan and Rau, Monika and Feuchtenberger, Martin and Schwaneck, Eva and Wallace, Sebastian J. and Cockell, Simon and Wilson-Kanamori, John and Ramachandran, Prakash and Kho, Celia and Kendall, Timothy J. and Leblond, Anne-Laure and Keppler, Selina J. and Bielecki, Piotr and Steiger, Katja and Hofmann, Maike and Rippe, Karsten and Zitzelsberger, Horst and Weber, Achim and Malek, Nisar and Luedde, Tom and Vucur, Mihael and Augustin, Hellmut and Flavell, Richard and Parnas, Oren and Rad, Roland and Pabst, Olivier and Henderson, Neil C. and Huber, Samuel and Macpherson, Andrew and Knolle, Percy and Claassen, Manfred and Geier, Andreas and Trautwein, Christoph and Unger, Kristian and Elinav, Eran and Waisman, Ari and Abdullah, Zeinab and Haller, Dirk and Tacke, Frank and Anstee, Quentin M. and Heikenw{\"a}lder, Mathias}, title={Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling}, year={2023}, pages={296-313}, language={eng}, issn={1600-0641}, volume={79}, number={2 vom: Aug.}, note={Online verf{\"u}gbar: 22. Mai 2023, Artikelversion: 14. Juli 2023 ; Gesehen am 12.10.2023}, journal={Journal of hepatology}, doi={10.1016/j.jhep.2023.04.037}, } @article{UBHD-68212654, author={La Porta, Silvia and Roth, Lise and Singhal, Mahak and Savant, Soniya and Augustin, Hellmut}, title={Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis}, year={2018}, pages={834-845}, language={eng}, issn={1558-8238}, volume={128}, number={2}, note={Gesehen am 23.01.2018}, journal={The journal of clinical investigation}, doi={10.1172/JCI94674}, } @article{UBHD-68286035, author={Leibing, Thomas and Géraud, Cyrill and Boutros, Michael and Augustin, Hellmut and Okun, J{\"u}rgen G. and Langhans, Claus-Dieter and Zierow, Johanna and Wohlfeil, Sebastian A. and Olsavszky, Victor and Schledzewski, Kai and Goerdt, Sergij and Reiners-Koch, Philipp-Sebastian}, title={Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice}, year={2018}, pages={707-722}, language={eng}, issn={1527-3350}, volume={68}, number={2}, note={First published: 23 October 2017 ; Gesehen am 28.03.2019}, journal={Hepatology}, doi={10.1002/hep.29613}, } @article{UBHD-68326950, author={Liebler, Sven Stefan and Feldner, Anja and Adam, M. Gordian and Korff, Thomas and Augustin, Hellmut and Fischer, Andreas}, title={No evidence for a functional role of bi-directional notch signaling during angiogenesis}, year={2012}, pages={10 S.}, language={eng}, issn={1932-6203}, volume={7}, note={Gesehen am 10.11.2018}, journal={PLOS ONE}, doi={10.1371/journal.pone.0053074}, } @article{UBHD-68430737, author={Maida, Adriano and Augustin, Hellmut and Herzig, Stephan and Rose, Adam J.}, title={Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance}, year={2018}, pages={189-196}, language={eng}, issn={1873-4847}, volume={57}, note={Available online 7 April 2018 ; Gesehen am 17.09.2019}, journal={The journal of nutritional biochemistry}, doi={10.1016/j.jnutbio.2018.03.027}, } @article{UBHD-68481906, author={Malehmir, Mohsen and Olkus, Alexander and Augustin, Hellmut and Vegiopoulos, Alexandros and Milsom, Michael}, title={Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer}, year={2019}, pages={641-655}, language={eng}, issn={1546-170X}, volume={25}, number={4}, note={Gesehen am 29.01.2020}, journal={Nature medicine}, doi={10.1038/s41591-019-0379-5}, } @article{UBHD-68303842, author={Manavski, Yosif and Hu, Junhao and Augustin, Hellmut}, title={Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin A}, year={2017}, pages={3993-3998}, language={eng}, issn={1091-6490}, volume={114}, number={15}, note={Gesehen am 11.09.2018}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.1613392114}, } @article{UBHD-68448184, author={Meln, Irina and Augustin, Hellmut}, title={Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth}, year={2019}, pages={139-148}, language={eng}, issn={2212-8778}, volume={24}, note={Gesehen am 30.10.2019 ; Available online 5 April 2019}, journal={Molecular metabolism}, doi={10.1016/j.molmet.2019.03.012}, } @article{UBHD-68244702, author={Mogler, Carolin and K{\"o}nig, Courtney and Wieland, Matthias and Runge, Anja and Schirmacher, Peter and Augustin, Hellmut}, title={Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin}, year={2017}, pages={741-749}, language={eng}, issn={1757-4684}, volume={9}, number={6}, note={Gesehen am 18.04.2018}, journal={EMBO molecular medicine}, doi={10.15252/emmm.201607222}, } @article{UBHD-67780169, author={Mogler, Carolin and K{\"o}nig, Courtney and Breitkopf-Heinlein, Katja and Dooley, Steven and Schirmacher, Peter and Longerich, Thomas and Augustin, Hellmut}, title={Hepatic stellate cell‐expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage}, year={2015}, pages={332-338}, language={eng}, issn={1757-4684}, volume={7}, number={3}, note={Gesehen am 26.02.2015}, journal={EMBO molecular medicine}, doi={10.15252/emmm.201404246}, } @article{UBHD-68898664, author={Nacak, Tanju and Alajati, Abdullah and Leptien, Kerstin and Fulda, Christine and Weber, Holger and Miki, Toru and Czepluch, Frauke S. and Waltenberger, Johannes and Wieland, Thomas and Augustin, Hellmut and Kroll, Jens}, title={The BTB-kelch protein KLEIP controls endothelial migration and sprouting angiogenesis}, year={2007}, pages={1155-1163}, language={eng}, issn={1524-4571}, volume={100}, number={8}, note={Gesehen am 23.03.2022}, journal={Circulation research}, doi={10.1161/01.RES.0000265844.56493.ac}, } @article{UBHD-67383639, author={Niland, Stephan and Ditkowski, Bartosz and Parrandier, Désirée and Roth, Lise and Augustin, Hellmut and Eble, Johannes A.}, title={Rhodocetin-αβ-induced neuropilin-1-cMet association triggers restructuring of matrix contacts in endothelial cells}, year={2013}, pages={544-554}, language={eng}, issn={1079-5642}, volume={33}, number={3}, journal={Arteriosclerosis, thrombosis, and vascular biology}, } @article{UBHD-68870970, author={Niland, Stephan and Ditkowski, Bartosz and Parrandier, Désirée and Roth, Lise and Augustin, Hellmut and Eble, Johannes A.}, title={Rhodocetin-αβ-induced neuropilin-1-cMet association triggers restructuring of matrix contacts in endothelial cells}, year={2013}, pages={544-554}, language={eng}, issn={1524-4636}, volume={33}, number={3}, note={Gesehen am 26.01.2022}, journal={Arteriosclerosis, thrombosis, and vascular biology}, doi={10.1161/ATVBAHA.112.00006}, } @article{UBHD-68493698, author={Nowak-Sliwinska, Patrycja and Alitalo, Kari and Allen, Elizabeth and Anisimov, Andrey and Aplin, Alfred C. and Auerbach, Robert and Augustin, Hellmut and Bates, David O. and van Beijnum, Judy R. and Bender, R. Hugh F. and Bergers, Gabriele and Bikfalvi, Andreas and Bischoff, Joyce and B{\"o}ck, Barbara and Brooks, Peter C. and Bussolino, Federico and Cakir, Bertan and Carmeliet, Peter and Castranova, Daniel and Cimpean, Anca M. and Cleaver, Ondine and Coukos, George and Davis, George E. and De Palma, Michele and Dimberg, Anna and Dings, Ruud P. M. and Djonov, Valentin and Dudley, Andrew C. and Dufton, Neil P. and Fendt, Sarah-Maria and Ferrara, Napoleone and Fruttiger, Marcus and Fukumura, Dai and Ghesquière, Bart and Gong, Yan and Griffin, Robert J. and Harris, Adrian L. and Hughes, Christopher C. W. and Hultgren, Nan W. and Iruela-Arispe, M. Luisa and Irving, Melita and Jain, Rakesh K. and Kalluri, Raghu and Kalucka, Joanna and Kerbel, Robert S. and Kitajewski, Jan and Klaassen, Ingeborg and Kleinmann, Hynda K. and Koolwijk, Pieter and Kuczynski, Elisabeth}, title={Consensus guidelines for the use and interpretation of angiogenesis assays}, year={2018}, pages={425-532}, language={eng}, issn={1573-7209}, volume={21}, number={3}, note={Gesehen am 26.02.2020}, journal={Angiogenesis}, doi={10.1007/s10456-018-9613-x}, } @article{UBHD-68766184, author={Paredes Ugarte, Isidora B. and Cruz Vieira, José Ricardo da and Shah, Bhavin and Ramunno, Carla F. and Dyckow, Julia and Adler, Heike and Richter, Melanie and Schermann, Géza and Giannakouri, Evangelia and Schirmer, Lucas and Augustin, Hellmut and Ruiz de Almodóvar, Carmen}, title={Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk}, year={2021}, pages={478-488}, language={eng}, issn={1546-1726}, volume={24}, number={4}, note={Gesehen am 02.08.2021}, journal={Nature neuroscience}, doi={10.1038/s41593-020-00788-z}, } @article{UBHD-68448831, author={Park, Jin-Sung and Augustin, Hellmut}, title={Normalization of tumor vessels by Tie2 activation and Ang2 inhibition enhances drug delivery and produces a favorable tumor microenvironment}, year={2016}, pages={953-967}, language={eng}, issn={1878-3686}, volume={30}, number={6}, note={Gesehen am 31.10.2019}, journal={Cancer cell}, doi={10.1016/j.ccell.2016.10.018}, } @article{UBHD-69112892, author={Preuss, Stephanie and Grieshober, Denise and Augustin, Hellmut}, title={Systemic reprogramming of endothelial cell signaling in metastasis and Cachexia}, year={2023}, pages={189-202}, language={eng}, issn={1548-9221}, volume={38}, number={4 vom: Juli}, note={Gesehen am 15.08.2023}, journal={Physiology}, doi={10.1152/physiol.00001.2023}, } @article{UBHD-68420240, author={Rathnakumar, Kumaragurubaran and Augustin, Hellmut}, title={Angiopoietin-2 mediates thrombin-induced monocyte adhesion and endothelial permeability}, year={2016}, pages={1655-1667}, language={eng}, issn={1538-7836}, volume={14}, number={8}, note={Gesehen am 13.08.2019}, journal={Journal of thrombosis and haemostasis}, doi={10.1111/jth.13376}, } @article{UBHD-69114536, author={Reiners-Koch, Philipp-Sebastian and Lee, Ki Hong and Goerdt, Sergij and Augustin, Hellmut}, title={Angiodiversity and organotypic functions of sinusoidal endothelial cells}, year={2021}, pages={289-310}, language={eng}, issn={1573-7209}, volume={24}, number={2}, note={Gesehen am 21.08.2023}, journal={Angiogenesis}, doi={10.1007/s10456-021-09780-y}, url={https://doi.org/10.1007/s10456-021-09780-y}, library={UB}, } @article{UBHD-68263237, author={Rios Garcia, Marcos and Singhal, Mahak and Augustin, Hellmut and Nawroth, Peter Paul and Herzig, Stephan and Berriel Diaz, Mauricio}, title={Acetyl-CoA carboxylase 1-dependent protein acetylation controls breast cancer metastasis and recurrence}, year={2017}, pages={19 S.}, language={eng}, issn={1932-7420}, volume={26(2017}, note={Available online 19 October 2017 ; Gesehen am 20.06.2018}, journal={Cell metabolism}, doi={10.1016/j.cmet.2017.09.018}, } @article{UBHD-68381732, author={Roth, Lise and Augustin, Hellmut}, title={Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation}, year={2016}, pages={?}, language={eng}, issn={1937-9145}, volume={9(2016}, number={425) Artikel-Nummer ra42}, note={Gesehen am 23.04.2019}, journal={Science signaling}, doi={10.1126/scisignal.aad3812}, } @article{UBHD-67882186, author={Runge, Anja and Bergeest, Jan-Philip and Mogler, Carolin and Géraud, Cyrill and Rohr, Karl and Schirmacher, Peter and Goerdt, Sergij and Augustin, Hellmut}, title={An inducible hepatocellular carcinoma model for preclinical evaluation of antiangiogenic therapy in adult mice}, year={2014}, pages={4157-4169}, language={eng}, issn={1538-7445}, volume={74}, number={15}, note={Gesehen am: 07.10.2015}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-13-2311}, } @article{UBHD-68227577, author={Savant, Soniya and Tisch, Nathalie and Ruiz de Almodóvar, Carmen and Augustin, Hellmut}, title={The orphan receptor Tie1 controls angiogenesis and vascular remodeling by differentially regulating Tie2 in tip and stalk cells}, year={2015}, pages={1761-1773}, language={eng}, issn={2211-1247}, volume={12}, number={11}, note={Gesehen am 07.03.2018}, journal={Cell reports}, doi={10.1016/j.celrep.2015.08.024}, } @article{UBHD-68544084, author={Schlereth, Katharina and Weichenhan, Dieter and Bauer, Tobias and Heumann, Tina and Giannakouri, Evangelia and Lipka, Daniel and Jaeger, Samira and Schlesner, Matthias and Aloy, Patrick and Eils, Roland and Plass, Christoph and Augustin, Hellmut}, title={The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium}, year={2018}, pages={1-23}, language={eng}, issn={2050-084X}, volume={7}, number={Artikel-ID e34423}, note={Published: 11 May 2018 ; Gesehen am 19.03.2020}, journal={eLife}, doi={10.7554/eLife.34423}, } @article{UBHD-68420592, author={Schneller, Doris and Kapel, Stephanie and Besemfelder, Eva and Augustin, Hellmut}, title={Cytokine-Like 1 is a novel proangiogenic factor secreted by and mediating functions of endothelial progenitor cells}, year={2019}, pages={243-255}, language={eng}, issn={1524-4571}, volume={124}, number={2}, note={Originally published: October 26, 2018 ; Gesehen am 14.08.2019}, journal={Circulation research}, doi={10.1161/CIRCRESAHA.118.313645}, } @article{UBHD-68357935, author={Scholz, Beate and Wojtarowicz, Jessica and Mogler, Carolin and Boutros, Michael and Augustin, Hellmut}, title={Endothelial RSPO3 controls vascular stability and pruning through non-canonical WNT/Ca2+/NFAT signaling}, year={2016}, pages={79-93}, language={eng}, issn={1878-1551}, volume={36}, number={1}, note={Gesehen am 12.02.2019}, journal={Developmental cell}, doi={10.1016/j.devcel.2015.12.015}, } @article{UBHD-68563081, author={Schreiber, Caroline and Saraswati, Supriya and Harkins, Shannon and Gruber, Annette and Cremers, Natascha and Thiele, Wilko and Rothley, Melanie and Plaumann, Diana and Korn, Claudia and Armant, Olivier and Augustin, Hellmut and Sleeman, Jonathan P.}, title={Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling}, year={2019}, pages={25 S.}, language={eng}, issn={1553-7404}, volume={15(2019}, note={Gesehen am 08.04.2020}, journal={PLoS Genetics}, doi={10.1371/journal.pgen.1008216}, } @article{UBHD-68587294, author={Selvaraj, Deepitha and Gangadharan, Vijayan and Michalski, Christoph and Kurejova, Martina and St{\"o}sser, Sebastian and Srivastava, Kshitij and Schweizerhof, Matthias and Waltenberger, Johannes and Ferrara, Napoleone and Heppenstall, Paul and Shibuya, Masabumi and Augustin, Hellmut and Kuner, Rohini}, title={Erratum}, subtitle={a functional role for VEGFR1 expressed in peripheral sensory neurons in cancer pain}, year={2015}, pages={270}, language={eng}, issn={1878-3686}, volume={28}, number={2}, note={Gesehen am 16.06.2020}, journal={Cancer cell}, doi={10.1016/j.ccell.2015.07.009}, } @article{UBHD-67833220, author={Selvaraj, Deepitha and Gangadharan, Vijayan and Michalski, Christoph and Augustin, Hellmut and Kuner, Rohini}, title={A functional role for VEGFR1 expressed in peripheral sensory neurons in cancer pain}, year={2015}, pages={780-796}, language={eng}, issn={1878-3686}, volume={27}, number={6}, journal={Cancer cell}, doi={10.1016/j.ccell.2015.04.017}, } @article{UBHD-68407259, author={Shen, Zhe and Liu, Yan and Dewidar, Bedair and Hu, Junhao and Park, Ogyi and Feng, Teng and Xu, Chengfu and Yu, Chaohui and Li, Qi and Meyer, Christoph and Ilkavets, Iryna and M{\"u}ller, Alexandra and Stump-Guthier, Carolin and Munker, Stefan and Liebe, Roman and Zimmer, Vincent and Lammert, Frank and Mertens, Peter R. and Li, Hai and Dijke, Peter ten and Augustin, Hellmut and Li, Jun and Gao, Bin and Ebert, Matthias and Dooley, Steven and Li, Youming and Weng, Honglei}, title={Delta-like ligand 4 modulates liver damage by down-regulating chemokine expression}, year={2016}, pages={1874-1889}, language={eng}, issn={1525-2191}, volume={186}, number={7}, note={Gesehen am 11.07.2019}, journal={The American journal of pathology}, doi={10.1016/j.ajpath.2016.03.010}, } @article{UBHD-68348970, author={Simons, Michael and Augustin, Hellmut}, title={State-of-the-art methods for evaluation of angiogenesis and tissue vascularization}, year={2015}, pages={e99-e132}, language={eng}, issn={1524-4571}, volume={116}, number={11}, note={Gesehen am 17.01.2019}, journal={Circulation research}, doi={10.1161/RES.0000000000000054}, } @article{UBHD-68441037, author={Singhal, Mahak and Liu, Xiaoting and Inverso, Donato and Jiang, Kai and Dai, Jianing and He, Hao and Bartels, Susanne and Li, Weiping and Abdul Pari, Ashik Ahmed and Gengenbacher, Nicolas and Besemfelder, Eva and Hui, Lijian and Augustin, Hellmut and Hu, Junhao}, title={Endothelial cell fitness dictates the source of regenerating liver vasculature}, year={2018}, pages={2497-2508}, language={eng}, issn={1540-9538}, volume={215}, number={10}, note={Gesehen am 16.10.2019}, journal={Journal of experimental medicine}, doi={10.1084/jem.20180008}, } @article{UBHD-68642795, author={Singhal, Mahak and Gengenbacher, Nicolas and La Porta, Silvia and Gehrs, Stephanie and Shi, Jingjing and Kamiyama, Miki and Bodenmiller, Diane M and Fischl, Anthony and Schieb, Benjamin and Besemfelder, Eva and Chintharlapalli, Sudhakar and Augustin, Hellmut}, title={Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody}, year={2020}, pages={9 S.}, language={eng}, issn={1757-4684}, volume={12(2020}, note={Gesehen am 05.10.2020}, journal={EMBO molecular medicine}, doi={10.15252/emmm.201911164}, } @article{UBHD-68793222, author={Singhal, Mahak and Gengenbacher, Nicolas and Abdul Pari, Ashik Ahmed and Kamiyama, Miki and Hai, Ling and Kuhn, Bianca and Kallenberg, David M. and Kulkarni, Shubhada and Camilli, Carlotta and Preuss, Stephanie and Leuchs, Barbara and Mogler, Carolin and Espinet, Elisa and Besemfelder, Eva and Heide, Danijela and Heikenwalder, Mathias and Sprick, Martin and Trumpp, Andreas and Krijgsveld, Jeroen and Schlesner, Matthias and Hu, Junhao and Moss, Stephen E. and Greenwood, John and Augustin, Hellmut}, title={Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis}, year={2021}, pages={1-14}, language={eng}, issn={1946-6242}, volume={13}, note={Gesehen am 25.10.2021}, journal={Science translational medicine}, doi={10.1126/scitranslmed.abe6805}, } @article{UBHD-69322435, author={Soleder, Stefan and Gengenbacher, Nicolas and Mogler, Carolin and Eckstein, Markus and Runge, Anja and Kriegmair, Maximilian and Augustin, Hellmut}, title={Development of a novel immunocompetent murine tumor model for urothelial carcinoma using in vivo electroporation}, year={2024}, pages={1-13}, language={eng}, issn={2045-2322}, volume={14}, number={Artikel-ID 25619}, note={Gesehen am 26.03.2025}, journal={Scientific reports}, doi={10.1038/s41598-024-77178-z}, } @article{UBHD-67754388, author={Srivastava, Kshitij and Teichert, Martin and Augustin, Hellmut}, title={Postsurgical adjuvant tumor therapy by combining anti-angiopoietin-2 and metronomic chemotherapy limits metastatic growth}, year={2014}, pages={880-895}, language={eng}, issn={1878-3686}, volume={26}, number={6}, note={Gesehen am: 13.01.2015}, journal={Cancer cell}, doi={10.1016/j.ccell.2014.11.005}, } @article{UBHD-69357372, author={Sugimoto, Atsushi and Saito, Yoshinobu and Wang, Guanxiong and Sun, Qiuyan and Yin, Chuan and Lee, Ki Hong and Geng, Yana and Rajbhandari, Presha and Hernandez, Celine and Steffani, Marcella and Qie, Jingran and Savage, Thomas and Goyal, Dhruv M. and Ray, Kevin C. and Neelakantan, Taruna V. and Yin, Deqi and Melms, Johannes and Lehrich, Brandon M. and Yasaka, Tyler M. and Liu, Silvia and Oertel, Michael and Lan, Tian and Guillot, Adrien and Peiseler, Moritz and Filliol, Aveline and Kanzaki, Hiroaki and Fujiwara, Naoto and Ravi, Samhita and Izar, Benjamin and Brosch, Mario and Hampe, Jochen and Remotti, Helen and Argemi, Josepmaria and Sun, Zhaoli and Kendall, Timothy J. and Hoshida, Yujin and Tacke, Frank and Fallowfield, Jonathan A. and Blockley-Powell, Storm K. and Haeusler, Rebecca A. and Steinman, Jonathan B. and Pajvani, Utpal B. and Monga, Satdarshan P. and Bataller, Ramon and Masoodi, Mojgan and Arpaia, Nicholas and Lee, Youngmin A. and Stockwell, Brent R. and Augustin, Hellmut and Schwabe, Robert F.}, title={Hepatic stellate cells control liver zonation, size and functions via R-spondin 3}, year={2025}, pages={752-761}, language={eng}, issn={1476-4687}, volume={640}, number={8059}, note={Online ver{\"o}ffentlicht: 12. M{\"a}rz 2025 ; Gesehen am 18.06.2025}, journal={Nature}, doi={10.1038/s41586-025-08677-w}, } @article{UBHD-69326083, author={Tauch, Saskia and Kast, Bettina and Lohr, Sabrina and Kemm, Lowis and Sator-Schmitt, Melanie and Gengenbacher, Nicolas and Augustin, Hellmut and Angel, Peter}, title={CAF specific expression of podoplanin may be dispensable for the malignancy of malignant melanoma}, subtitle={brief communication}, year={2025}, pages={215-220}, language={eng}, issn={1098-2744}, volume={64}, number={2 vom: Feb.}, note={Erstmals ver{\"o}ffentlicht: 08. November 2024 ; Gesehen am 01.04.2025}, journal={Molecular carcinogenesis}, doi={10.1002/mc.23841}, } @article{UBHD-69357366, author={Tauch, Saskia and Hey, Joschka and Kast, Bettina and Gengenbacher, Nicolas and Weiß, Lena and Sator-Schmitt, Melanie and Lohr, Sabrina and Brobeil, Alexander and Schirmacher, Peter and Utikal, Jochen and Augustin, Hellmut and Plass, Christoph and Angel, Peter}, title={A unique signature for cancer-associated fibroblasts in melanoma metastases}, year={2025}, pages={1-9}, language={eng}, issn={1755-148X}, volume={38}, note={Online ver{\"o}ffentlicht: 9. Februar 2025 ; Gesehen am 18.06.2025}, journal={Pigment cell & melanoma research}, doi={10.1111/pcmr.70002}, } @article{UBHD-68209585, author={Teichert, Martin and Booken, Nina and Mogler, Carolin and Andrulis, Mindaugas and Nicolay, Jan Peter and Goerdt, Sergij and Klemke, Claus-Detlev and Augustin, Hellmut and Felcht, Moritz}, title={Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesis}, year={2015}, pages={424-429}, language={eng}, issn={1600-0625}, volume={24}, number={6}, note={Gesehen am 15.01.2018}, journal={Experimental dermatology}, doi={10.1111/exd.12688}, } @article{UBHD-68165770, author={Teichert, Martin and Savant, Soniya and Augustin, Hellmut}, title={Pericyte-expressed Tie2 controls angiogenesis and vessel maturation}, year={2017}, pages={12 S.}, language={eng}, issn={2041-1723}, volume={8(2017) Artikel-Nummer 16106}, number={12 Seiten}, note={Gesehen am 14.09.2017}, journal={Nature Communications}, doi={10.1038/ncomms16106}, } @article{UBHD-69143108, author={Thomas, Markus and Felcht, Moritz and Kruse, Karoline and Kretschmer, Stella and Deppermann, Carleen and Biesdorf, Andreas and Rohr, Karl and Benest, Andrew V. and Fiedler, Ulrike and Augustin, Hellmut}, title={Angiopoietin-2 stimulation of endothelial cells induces αvβ3 integrin internalization and degradation}, year={2010}, pages={23842-23849}, language={eng}, issn={1083-351X}, volume={285}, number={31}, note={Gesehen am 15.11.2023}, journal={The journal of biological chemistry}, doi={10.1074/jbc.M109.097543}, } @article{UBHD-69181143, author={Tisch, Nathalie and Mogler, Carolin and Stojanovic, Ana and Luck, Robert and Korhonen, Emilia Anne and Ellerkmann, Alexander and Adler, Heike and Singhal, Mahak and Schermann, Géza and Erkert, Lena and Patankar, Jay V and Karakatsani, Andromachi and Scherr, Anna-Lena and Fuchs, Yaron and Cerwenka, Adelheid and Wirtz, Stefan and K{\"o}hler, Bruno Christian and Augustin, Hellmut and Becker, Christoph and Schmidt, Thomas and Ruiz de Almodóvar, Carmen}, title={Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice}, year={2022}, pages={1-21}, language={eng}, issn={1757-4684}, volume={14}, note={Gesehen am 12.02.2024}, journal={EMBO molecular medicine}, doi={10.15252/emmm.202114121}, } @article{UBHD-68480423, author={Tisch, Nathalie and Freire Valls, Aida and Yerbes, Rosario and Paredes Ugarte, Isidora B. and La Porta, Silvia and Wang, Xiaohong and Martín-Pérez, Rosa and Castro, Laura and Wong, Wendy Wei-Lynn and Coultas, Leigh and Strilic, Boris and Gr{\"o}ne, Hermann-Josef and Hielscher, Thomas and Mogler, Carolin and Adams, Ralf H. and Heiduschka, Peter and Claesson-Welsh, Lena and Mazzone, Massimiliano and López-Rivas, Abelardo and Schmidt, Thomas and Augustin, Hellmut and Ruiz de Almodóvar, Carmen}, title={Caspase-8 modulates physiological and pathological angiogenesis during retina development}, year={2019}, pages={5092-5107}, language={eng}, issn={1558-8238}, volume={129}, number={12}, note={Gesehen am 24.01.2020}, journal={The journal of clinical investigation}, doi={10.1172/JCI122767}, } @article{UBHD-68349772, author={Viski, Carmen and K{\"o}nig, Courtney and Mogler, Carolin and Augustin, Hellmut}, title={Endosialin-expressing pericytes promote metastatic dissemination}, year={2016}, pages={5313-5325}, language={eng}, issn={1538-7445}, volume={76}, number={18}, note={Gesehen am 21.01.2019 ; Published online September 15, 2016}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-16-0932}, } @article{UBHD-69216603, author={W{\"u}stehube-Lausch, Joycelyn and Bartol, Arne and Liebler, Sven Stefan and Br{\"u}tsch, René Michael and Zhu, Yuan and Felbor, Ute and Sure, Ulrich and Augustin, Hellmut and Fischer, Andreas}, title={Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling}, year={2010}, pages={12640-12645}, language={eng}, issn={1091-6490}, volume={107}, number={28}, note={Gesehen am 22.05.2024}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.1000132107}, } @article{UBHD-68236892, author={Yang, Wan-Jen and Augustin, Hellmut and Fischer, Andreas}, title={Semaphorin‐3C signals through Neuropilin‐1 and PlexinD1 receptors to inhibit pathological angiogenesis}, year={2015}, pages={1267-1284}, language={eng}, issn={1757-4684}, volume={7}, number={10}, note={Gesehen am 27.03.2018}, journal={EMBO molecular medicine}, doi={10.15252/emmm.201404922}, } @article{UBHD-67919305, author={Zheng, Wei and Augustin, Hellmut}, title={Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions}, year={2014}, pages={1592-1603}, language={eng}, issn={1549-5477}, volume={28}, number={1}, note={Gesehen am: 22.12.2015}, journal={Genes & development}, doi={10.1101/gad.237677.114}, } @article{UBHD-67702126, author={Ziegler, Tilman and Augustin, Hellmut}, title={Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis}, year={2013}, pages={3436-3445}, language={eng}, issn={1558-8238}, volume={123}, number={8}, note={Gesehen am: 11.11.2014}, journal={The journal of clinical investigation}, doi={10.1172/JCI66549}, }