@article{UBHD-69154140, author={Aklillu, Eleni and Zumla, Alimuddin and Habtewold, Abiy and Amogne, Wondwossen and Makonnen, Eyasu and Yimer, Getnet and Burhenne, J{\"u}rgen and Diczfalusy, Ulf}, title={Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients}, year={2021}, pages={3294-3308}, language={eng}, issn={1476-5381}, volume={178}, number={16 vom: Aug.}, note={Gesehen am 18.12.2023}, journal={British journal of pharmacology}, doi={10.1111/bph.15309}, } @article{UBHD-68738848, author={Akoachere, Monique B. and Buchholz, Kathrin and Fischer, Elisabeth and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Schirmer, Rolf Heiner and Becker, Katja}, title={In vitro assessment of methylene blue on chloroquine-sensitive and -resistant plasmodium falciparum strains reveals synergistic action with artemisinins}, year={2005}, pages={4592-4597}, language={eng}, issn={1098-6596}, volume={49}, number={11}, note={Gesehen am 18.05.2021}, journal={Antimicrobial agents and chemotherapy}, doi={10.1128/AAC.49.11.4592-4597.2005}, } @article{UBHD-67569349, author={Albarmawi, Albader and Czock, David and Gauss, Annika and Ehehalt, Robert and Lorenzo Bermejo, Justo and Burhenne, J{\"u}rgen and Ganten, Tom M. and Sauer, Peter and Haefeli, Walter E.}, title={CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores}, year={2014}, pages={160-169}, language={eng}, issn={1365-2125}, volume={77}, number={1}, note={Gesehen am 15.04.2014}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.12182}, } @article{UBHD-68913984, author={Alborzinia, Hamed and Flórez, Andrés F. and Kreth, Sina and Br{\"u}ckner, Lena M. and Yildiz, Umut and Gartlgruber, Moritz and Odoni, Dorett and Poschet, Gernot and Garbowicz, Karolina and Shao, Chunxuan and Klein, Corinna and Meier, Jasmin and Zeisberger, Petra and Nadler-Holly, Michal and Ziehm, Matthias and Paul, Franziska and Burhenne, J{\"u}rgen and Bell, Emma and Shaikhkarami, Marjan and W{\"u}rth, Roberto and Stainczyk, Sabine A. and Wecht, Elisa M. and Kreth, Jochen and B{\"u}ttner, Michael and Ishaque, Naveed and Schlesner, Matthias and Nicke, Barbara and Stresemann, Carlo and Llamazares Prada, Maria and Reiling, Jan H. and Fischer, Matthias and Amit, Ido and Selbach, Matthias and Herrmann, Carl and W{\"o}lfl, Stefan and Henrich, Kai-Oliver and H{\"o}fer, Thomas and Trumpp, Andreas and Westermann, Frank}, title={MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis}, year={2022}, pages={471-485}, language={eng}, issn={2662-1347}, volume={3}, number={4}, note={Das PDF enth{\"a}lt zus{\"a}tzlich einen Anhang von 16 Seiten ; Gesehen am 03.05.2022}, journal={Nature cancer}, doi={10.1038/s43018-022-00355-4}, } @article{UBHD-68246624, author={Ali, Ramadan Mahmoud Mohamed and Campos, Benito and Dyckhoff, Gerhard and Haefeli, Walter E. and Herold-Mende, Christel and Burhenne, J{\"u}rgen}, title={Quantification of retinoid concentrations in human serum and brain tumor tissues}, year={2012}, pages={57-66}, language={eng}, issn={1873-4324}, volume={725}, note={Gesehen am 25.04.2018}, journal={Analytica chimica acta}, doi={10.1016/j.aca.2012.03.003}, } @article{UBHD-68739412, author={Alkan, Yoav and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Stein, J. and Yaniv, I. and Shalit, Itamar}, title={Voriconazole-induced QT interval prolongation and ventricular tachycardia}, subtitle={a non-concentration-dependent adverse effect}, year={2004}, pages={e49-e52}, language={eng}, issn={1537-6591}, volume={39}, number={6}, note={Gesehen am 19.05.2021}, journal={Clinical infectious diseases}, doi={10.1086/423275}, } @article{UBHD-68252255, author={Bajraktari-Sylejmani, Gzona and Burhenne, J{\"u}rgen and Bugert, Peter and Haefeli, Walter E. and Weiß, Johanna}, title={Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets}, year={2017}, pages={54-63}, language={eng}, issn={1873-2968}, volume={145}, note={Gesehen am 15.05.2018}, journal={Biochemical pharmacology}, doi={10.1016/j.bcp.2017.08.026}, } @article{UBHD-68963697, author={Bajraktari-Sylejmani, Gzona and Linde, Teresa von and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Sauter, Max and Weiß, Johanna}, title={Evaluation of PepT1 (SLC15A1) substrate characteristics of therapeutic cyclic peptides}, year={2022}, pages={1-11}, language={eng}, issn={1999-4923}, volume={14}, note={Gesehen am 13.09.2022}, journal={Pharmaceutics}, doi={10.3390/pharmaceutics14081610}, } @article{UBHD-69354051, author={Bajraktari-Sylejmani, Gzona and Bay, Cindy and Gebauer, Lukas and Burhenne, J{\"u}rgen and Weiß, Johanna and Sauter, Max}, title={A highly sensitive UPLC-MS/MS method for the quantification of the organic cation transporters' mediated metformin uptake and its inhibition in cells}, year={2024}, pages={[1]-14}, language={eng}, issn={1420-3049}, volume={29}, note={Online ver{\"o}ffentlicht: 31. Oktober 2024 ; Gesehen am 05.06.2025}, journal={Molecules}, doi={10.3390/molecules29215162}, } @article{UBHD-69194406, author={Bajraktari-Sylejmani, Gzona and Oster, Julia Sophie and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Sauter, Max and Weiß, Johanna}, title={In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo-keto reductases}, year={2024}, pages={807-820}, language={eng}, issn={1432-0738}, volume={98}, number={3}, note={Gesehen am 22.03.2024}, journal={Archives of toxicology}, doi={10.1007/s00204-023-03661-7}, } @article{UBHD-68220660, author={Bajraktari-Sylejmani, Gzona and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Weiß, Johanna}, title={The phosphodiesterase inhibitors sildenafil and tadalafil accumulate inside platelets in the presence of cyclic guanosine monophosphate}, year={2017}, language={eng}, issn={2050-6511}, volume={18(2017}, note={Gesehen am 15.02.2018}, journal={BMC pharmacology & toxicology}, doi={10.1186/s40360-017-0170-5}, } @article{UBHD-69063263, author={Bay, Cindy and Bajraktari-Sylejmani, Gzona and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Weiß, Johanna and Sauter, Max}, title={Correction}, subtitle={Bay et al. functional characterization of the solute carrier LAT-1 (SLC7A5/SLC3A2) in human brain capillary endothelial cells with rapid UPLC-MS/MS quantification of intracellular isotopically labelled L-leucine. Int. J. Mol. Sci. 2022, 23, 3637}, year={2023}, pages={1}, language={eng}, issn={1422-0067 and 1661-6596}, volume={24}, note={Gesehen am 06.12.2023}, journal={International journal of molecular sciences}, doi={10.3390/ijms24055029}, } @article{UBHD-68904502, author={Bay, Cindy and Bajraktari-Sylejmani, Gzona and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Weiß, Johanna and Sauter, Max}, title={Functional characterization of the aolute carrier LAT-1 (SLC7A5/SLC2A3) in human brain capillary endothelial cells with rapid UPLC-MS/MS quantification of intracellular isotopically labelled L-Leucine}, year={2022}, pages={1-18}, language={eng}, issn={1422-0067 and 1661-6596}, volume={23}, note={Gesehen am 06.04.2022}, journal={International journal of molecular sciences}, doi={10.3390/ijms23073637}, url={https://doi.org/10.3390/ijms23073637}, library={UB}, } @article{UBHD-68807476, author={Benzel, Julia and Bajraktari-Sylejmani, Gzona and Uhl, Philipp and Davis, Abigail and Nair, Sreenath and Pfister, Stefan and Haefeli, Walter E. and Weiß, Johanna and Burhenne, J{\"u}rgen and Pajtler, Kristian Wilfried and Sauter, Max}, title={Investigating the central nervous system disposition of actinomycin D}, subtitle={implementation and evaluation of cerebral microdialysis and brain tissue measurements supported by UPLC-MS/MS quantification}, year={2021}, pages={1-16}, language={eng}, issn={1999-4923}, volume={13}, note={Gesehen am 02.12.2021 ; This article belongs to the special issue "Quantification of therapeutic peptides by LC-MS"}, journal={Pharmaceutics}, doi={10.3390/pharmaceutics13091498}, } @article{UBHD-68299233, author={Blank, Antje and Eidam, Annette and Hohmann, Nicolas and Burhenne, J{\"u}rgen and Meyer, Markus Robert and Meier, Katrin and Weiß, Johanna and Bruckner, Thomas and Urban, Stephan and Mikus, Gerd and Haefeli, Walter E.}, title={The NTCP-inhibitor Myrcludex B}, subtitle={effects on bile acid disposition and tenofovir pharmacokinetics}, year={2018}, pages={341-348}, language={eng}, issn={1532-6535}, volume={103}, number={2}, note={Gesehen am 27.08.2018 ; Advance online publication 21 June 2017}, journal={Clinical pharmacology & therapeutics}, doi={10.1002/cpt.744}, } @article{UBHD-68738824, author={Borwitzky, Holger and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Analysis of methylene blue in human urine by capillary electrophoresis}, year={2005}, pages={244-251}, language={eng}, issn={1873-376X}, volume={826}, number={1/2}, note={Gesehen am 18.05.2021}, journal={Journal of chromatography}, doi={10.1016/j.jchromb.2005.09.013}, } @article{UBHD-69041812, author={Bountogo, Mamadou and Zoungrana, Augustin and Coulibaly, Boubacar and Klose, Christina and Mansmann, Ulrich and Mockenhaupt, Frank P. and Burhenne, J{\"u}rgen and Mikus, Gerd and Walter-Sack, Ingeborg and Schirmer, Rolf Heiner and Sié, Ali and Meissner, Peter and M{\"u}ller, Olaf}, title={Efficacy of methylene blue monotherapy in semi-immune adults with uncomplicated falciparum malaria}, subtitle={a controlled trial in Burkina Faso}, year={2010}, pages={713-717}, language={eng}, issn={1365-3156}, volume={15}, number={6}, note={Gesehen am 15.02.2023}, journal={Tropical medicine & international health}, doi={10.1111/j.1365-3156.2010.02526.x}, } @article{UBHD-68412355, author={Brings, Antonia and Lehmann, Marie-Louise and Foerster, Kathrin and Burhenne, J{\"u}rgen and Weiß, Johanna and Haefeli, Walter E. and Czock, David}, title={Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers}, year={2019}, pages={1528-1537}, language={eng}, issn={1365-2125}, volume={85}, number={7}, note={Gesehen am 25.07.2019}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.13934}, } @article{UBHD-68259169, author={Burhenne, J{\"u}rgen}, title={Evaluation of the influence of formulation, food intake and species on voriconazole plasma concentration in birds}, year={2012}, pages={157-162}, language={eng}, volume={99}, note={Gesehen am 08.06.2018}, journal={Veterinary medicine Austria}, } @article{UBHD-68740529, author={Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Martin-Facklam, Meret and Mikus, Gerd and Haefeli, Walter E.}, title={Highly sensitive determination of saquinavir in biological samples using liquid chromatography-tandem mass spectrometry}, year={2003}, pages={233-242}, language={eng}, issn={1873-376X}, volume={784}, number={2}, note={Online 28 October 2002 ; Gesehen am 25.05.2021}, journal={Journal of chromatography}, doi={10.1016/S1570-0232(02)00803-6}, } @article{UBHD-68288835, author={Burhenne, J{\"u}rgen and Liu, Lu and Heilig, Christoph E. and Meid, Andreas and Kasper, Bernd and Haefeli, Walter E. and Mikus, Gerd and Egerer, Gerlinde}, title={Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients}, year={2017}, pages={433-439}, language={eng}, issn={1432-0843}, volume={80}, number={2}, note={Gesehen am 25.07.2018}, journal={Cancer chemotherapy and pharmacology}, doi={10.1007/s00280-017-3357-y}, } @article{UBHD-69054211, author={Burhenne, J{\"u}rgen and Matthée, Anne-Kathrin and Pasáková, Ivana and R{\"o}der, Claudia Stephanie and Heinrich, Tilman and Haefeli, Walter E. and Mikus, Gerd and Weiß, Johanna}, title={No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment}, year={2010}, pages={4185-4191}, language={eng}, issn={1098-6596}, volume={54}, number={10}, note={Gesehen am 22.03.2023}, journal={Antimicrobial agents and chemotherapy}, doi={10.1128/AAC.00283-10}, } @article{UBHD-68261264, author={Burhenne, J{\"u}rgen and Halama, Birte and Maurer, Monika and Riedel, Klaus-Dieter and Hohmann, Nicolas and Mikus, Gerd and Haefeli, Walter E.}, title={Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1′-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry}, year={2012}, pages={2439-2450}, language={eng}, issn={1618-2650}, volume={402}, number={7}, note={Die Zahl 3 ist im Titel tiefgestellt ; Gesehen am 14.06.2018}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-011-5675-y}, } @article{UBHD-67398865, author={Burhenne, J{\"u}rgen and Halama, Birte and Maurer, Monika and Riedel, Klaus-Dieter and Hohmann, Nicolas and Mikus, Gerd and Haefeli, Walter E.}, title={Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry}, year={2012}, pages={2439-2450}, language={eng}, issn={1618-2642}, volume={402}, number={7}, note={Die Zahl 3 ist im Titel tiefgestellt}, journal={Analytical & bioanalytical chemistry}, } @article{UBHD-68622194, author={Burhenne, J{\"u}rgen and Fresnais, Margaux and Steimel, Kevin}, title={Safety and activity of the combination of ceritinib and dasatinib in osteosarcoma}, year={2020}, pages={15 S.}, language={eng}, issn={2072-6694}, volume={12(2020}, note={Gesehen am 30.07.2020}, journal={Cancers}, doi={10.3390/cancers12040793}, } @article{UBHD-69054251, author={Burkhardt, Olaf and Thon, Simone and Burhenne, J{\"u}rgen and Welte, Tobias and Kielstein, Jan T.}, title={Sulphobutylether-β-cyclodextrin accumulation in critically ill patients with acute kidney injury treated with intravenous voriconazole under extended daily dialysis}, year={2010}, pages={93-94}, language={eng}, issn={1872-7913}, volume={36}, number={1 vom: Juli}, note={Letter to the editor ; Gesehen am 22.03.2023}, journal={International journal of antimicrobial agents}, doi={10.1016/j.ijantimicag.2010.02.017}, } @article{UBHD-68934833, author={Campos, Benito and Centner, Franz-Simon and Lorenzo Bermejo, Justo and Ali, Ramadan and Dorsch, Katharina and Wan, Feng and Felsberg, J{\"o}rg and Ahmadi, Rezvan and Grabe, Niels and Reifenberger, Guido and Unterberg, Andreas and Burhenne, J{\"u}rgen and Herold-Mende, Christel}, title={Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas}, year={2011}, pages={1953-1964}, language={eng}, issn={1525-2191}, volume={178}, number={5}, note={Gesehen am 27.06.2022}, journal={The American journal of pathology}, doi={10.1016/j.ajpath.2011.01.051}, } @article{UBHD-68656883, author={Campos, Benito and Weisang, Sarah Christina and Oßwald, Florian and Ali, Ramadan Mahmoud Mohamed and Sedlmeier, Georg and Bageritz, Josephine and Mallm, Jan-Philipp and Hartmann, Christian and Deimling, Andreas von and Popanda, Odilia and Goidts, Violaine and Plass, Christoph and Unterberg, Andreas and Schmezer, Peter and Burhenne, J{\"u}rgen and Herold-Mende, Christel}, title={Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma}, year={2015}, pages={1850-1859}, language={eng}, issn={1098-1136}, volume={63}, number={10}, note={Gesehen am 03.11.2020}, journal={Glia}, doi={10.1002/glia.22849}, } @article{UBHD-67738578, author={Carls, Alexandra and Winter, Julia and Enderle, Yeliz and Burhenne, J{\"u}rgen and Gorenflo, Matthias and Haefeli, Walter E.}, title={Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease}, subtitle={two case reports}, year={2014}, pages={1-5}, language={eng}, issn={1752-1947}, volume={8}, note={Gesehen am 26.11.2014}, journal={Journal of medical case reports}, doi={10.1186/1752-1947-8-171}, url={http://www.ncbi.nlm.nih.gov/pubmed/24885923}, library={UB}, } @article{UBHD-67879734, author={Carls, Alexandra and Jedamzik, Julia and Witt, Lukas and Hohmann, Nicolas and Burhenne, J{\"u}rgen and Mikus, Gerd}, title={Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity}, year={2014}, pages={1433-1440}, language={eng}, issn={1365-2125}, volume={78}, number={6}, note={Gesehen am 01.10.2015}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.12497}, } @article{UBHD-68293919, author={Clemens, Jannick and Welti, Lukas and Sch{\"a}fer, Julia and Seckinger, Anja and Burhenne, J{\"u}rgen and Theile, Dirk and Weiß, Johanna}, title={Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter‑based drug‑drug interactions}, year={2017}, pages={3185-3192}, language={eng}, issn={1792-1082}, volume={14}, number={3}, note={Gesehen am 09.08.2018}, journal={Oncology letters}, doi={10.3892/ol.2017.6560}, } @article{UBHD-68108062, author={Clemens, Jannick and Seckinger, Anja and Hose, Dirk and Theile, Dirk and Longo, Magdalena and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Weiß, Johanna}, title={Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters}, year={2015}, pages={281-291}, language={eng}, issn={1432-0843}, volume={75}, number={2}, note={Published online: 5 December 2014 ; Gesehen am 07.04.2017}, journal={Cancer chemotherapy and pharmacology}, doi={10.1007/s00280-014-2643-1}, } @article{UBHD-67976576, author={Clemens, Jannick and Longo, Magdalena and Seckinger, Anja and Hose, Dirk and Haefeli, Walter E. and Weiß, Johanna and Burhenne, J{\"u}rgen}, title={Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry}, year={2014}, pages={128-138}, language={eng}, issn={1873-3778}, volume={1345}, note={Gesehen am 10.05.2016}, journal={Journal of chromatography}, doi={10.1016/j.chroma.2014.04.024}, } @article{UBHD-68139064, author={Dettmer, Susan and Theile, Dirk and Seckinger, Anja and Burhenne, J{\"u}rgen and Weiß, Johanna}, title={Fetal calf sera can distort cell-based luminescent proteasome assays through heat-resistant chymotrypsin-like activity}, year={2015}, pages={23-25}, language={eng}, issn={1096-0309}, volume={471}, note={Published online: 4 November 2014 ; Gesehen am 17.07.2017}, journal={Analytical biochemistry}, doi={10.1016/j.ab.2014.10.019}, } @article{UBHD-68197515, author={Dettmer, Susan and Theile, Dirk and Sch{\"a}fer, Julia and Seckinger, Anja and Burhenne, J{\"u}rgen and Weiß, Johanna}, title={Proteasome inhibition correlates with intracellular bortezomib concentrations but not with antiproliferative effects after bolus treatment in myeloma cell lines}, year={2016}, pages={1091-1101}, language={eng}, issn={1432-1912}, volume={389}, number={10}, note={Gesehen am 04.12.2017}, journal={Naunyn-Schmiedeberg's archives of pharmacology}, doi={10.1007/s00210-016-1276-9}, } @article{UBHD-68739430, author={Ding, Reinhard and Tayrouz Haffar, Yorki Antoine and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers}, year={2004}, pages={73-84}, language={eng}, issn={1532-6535}, volume={76}, number={1}, note={Gesehen am 19.05.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1016/j.clpt.2004.02.008}, } @article{UBHD-69046871, author={Egerer, Gerlinde and Eisenlohr, Kathrin and Gronkowski, Martina and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Mikus, Gerd}, title={The NK1 receptor antagonist aprepitant does not alter the pharmacokinetics of high-dose melphalan chemotherapy in patients with multiple myeloma}, year={2010}, pages={903-907}, language={eng}, issn={1365-2125}, volume={70}, number={6 vom: Dez.}, note={Im Titel ist die Ziffer 1 bei "NK1" tiefgestellt ; Gesehen am 02.03.2023}, journal={British journal of clinical pharmacology}, doi={10.1111/j.1365-2125.2010.03792.x}, } @article{UBHD-68739434, author={Ehrhardt, Manuela and Lindenmaier, Heike and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Weiß, Johanna}, title={Influence of lipid lowering fibrates on P-glycoprotein activity in vitro}, year={2004}, pages={285-292}, language={eng}, issn={1873-2968}, volume={67}, number={2}, note={Online 3 December 2003 ; Gesehen am 19.05.2021}, journal={Biochemical pharmacology}, doi={10.1016/j.bcp.2003.09.008}, } @article{UBHD-68737255, author={Ehrhardt, Manuela and M{\"o}ck, Marion and Haefeli, Walter E. and Mikus, Gerd and Burhenne, J{\"u}rgen}, title={Monitoring of lopinavir and ritonavir in peripheral blood mononuclear cells, plasma, and ultrafiltrate using a selective and highly sensitive LC/MS/MS assay}, year={2007}, pages={249-258}, language={eng}, issn={1873-376X}, volume={850}, number={1}, note={Online 11 December 2006 ; Gesehen am 12.05.2021}, journal={Journal of chromatography}, doi={10.1016/j.jchromb.2006.11.037}, } @article{UBHD-68678343, author={Eichbaum, Christine and Cortese, Marianna and Blank, Antje and Burhenne, J{\"u}rgen and Mikus, Gerd}, title={Concentration effect relationship of CYP3A inhibition by ritonavir in humans}, year={2013}, pages={1795-1800}, language={eng}, issn={1432-1041}, volume={69}, number={10}, note={Gesehen am 08.01.2021}, journal={European journal of clinical pharmacology}, doi={10.1007/s00228-013-1530-8}, } @article{UBHD-68126764, author={Eichbaum, Christine and Mathes, Kristin and Burhenne, J{\"u}rgen and Markert, Christoph and Blank, Antje and Mikus, Gerd}, title={Pre-systemic elimination of tilidine}, subtitle={localization and consequences for the formation of the active metabolite nortilidine}, year={2015}, pages={129-133}, language={eng}, issn={1742-7843}, volume={116}, number={2}, note={Published online: 10 June 2014 ; Gesehen am 08.06.2017}, journal={Basic & clinical pharmacology & toxicology}, doi={10.1111/bcpt.12328}, } @article{UBHD-68185784, author={Enderle, Yeliz and Foerster, Kathrin and Burhenne, J{\"u}rgen}, title={Clinical feasibility of dried blood spots}, subtitle={analytics, validation, and applications}, year={2016}, pages={231-243}, language={eng}, issn={1873-264X}, volume={130}, number={Supplement C}, note={Gesehen am 03.11.2017}, journal={Journal of pharmaceutical and biomedical analysis}, doi={10.1016/j.jpba.2016.06.026}, } @article{UBHD-68616279, author={Enderle, Yeliz and Meid, Andreas and Friedrich, J{\"o}rg and Gr{\"u}nig, Ekkehard and Wilkens, Heinrike and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Dried blood spot technique for the monitoring of ambrisentan, bosentan, sildenafil, and tadalafil in patients with pulmonary arterial hypertension}, year={2015}, pages={12112-12120}, language={eng}, issn={1520-6882}, volume={87}, number={24}, note={Gesehen am 13.07.2020}, journal={Analytical chemistry}, doi={10.1021/acs.analchem.5b03077}, } @article{UBHD-68333420, author={Enderle, Yeliz and Witt, Lukas and Gr{\"u}nig, Ekkehard and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Simultaneous quantification of endothelin receptor antagonists and phosphodiesterase 5 inhibitors currently used in pulmonary arterial hypertension}, year={2017}, pages={291-298}, language={eng}, issn={1873-264X}, volume={143}, note={Gesehen am 28.11.2018}, journal={Journal of pharmaceutical and biomedical analysis}, doi={10.1016/j.jpba.2017.05.052}, } @article{UBHD-68564619, author={Foerster, Kathrin and Huppertz, Andrea and Meid, Andreas and M{\"u}ller, Oliver J. and Rizos, Timolaos and Tilemann, Lisa and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Dried-blood-spot technique to monitor direct oral anticoagulants}, subtitle={clinical validation of a UPLC-MS/MS-based assay}, year={2018}, pages={9395-9402}, language={eng}, issn={1520-6882}, volume={90}, number={15}, note={Gesehen am 15.04.2020}, journal={Analytical chemistry}, doi={10.1021/acs.analchem.8b02046}, } @article{UBHD-68482505, author={Fresnais, Margaux and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Advances in clinical pharmacology}, subtitle={rapid detection of small molecules in solid samples at atmospheric pressure using desorption electrospray ionization}, year={2019}, pages={53-54}, language={eng}, issn={1557-8100}, volume={24}, number={1}, note={Published online: 10 Jan 2020 ; Gesehen am 30.01.2020}, journal={OMICS}, doi={10.1089/omi.2019.0195}, } @article{UBHD-68956964, author={Fresnais, Margaux and Liang, Siwen and Breitkopf, Marius and Lindner, Joshua Raoul and Claude, Emmanuelle and Pringle, Steven and Levkin, Pavel and Demir, Konstantin and Benzel, Julia and Sundheimer, Julia and Statz, Britta and Pajtler, Kristian Wilfried and Pfister, Stefan and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Analytical performance evaluation of new DESI enhancements for targeted drug quantification in tissue sections}, year={2022}, pages={1-18}, language={eng}, issn={1424-8247}, volume={15}, note={Gesehen am 24.08.2022 ; This article belongs to the special issue "Mass spectrometry imaging in pharmaceutical research"}, journal={Pharmaceuticals}, doi={10.3390/ph15060694}, } @article{UBHD-68895339, author={Fresnais, Margaux and Turcan, S̨evin and Theile, Dirk and Ungermann, Johannes and Abou Zeed, Yasmin and Lindner, Joshua Raoul and Breitkopf, Marius and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Longuespée, Rémi}, title={Approaching sites of action of temozolomide for pharmacological and clinical studies in glioblastoma}, year={2022}, pages={1-27}, language={eng}, issn={2227-9059}, volume={10}, note={Published: 21 December 2021 ; Gesehen am 16.03.2022}, journal={Biomedicines}, doi={10.3390/biomedicines10010001}, } @article{UBHD-68882880, author={Fresnais, Margaux and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Longuespée, Rémi}, title={Desorption/ionization-MS methods for drug quantification in biological matrices and their validation following regulatory guidance}, year={2021}, pages={7152-7163}, language={eng}, issn={1520-6882}, volume={93}, number={19}, note={Gesehen am 25.02.2022}, journal={Analytical chemistry}, doi={10.1021/acs.analchem.1c00647}, } @article{UBHD-69099774, author={Fresnais, Margaux and Liang, Siwen and Seven, Deniz and Prodanovic, Nevena and Sundheimer, Julia and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Desorption kinetics evaluation for the development of validated desorption electrospray ionization-mass spectrometric assays for drug quantification in tissue sections}, year={2023}, pages={1-14}, language={eng}, issn={1422-0067 and 1661-6596}, volume={24}, note={Gesehen am 30.11.2023}, journal={International journal of molecular sciences}, doi={10.3390/ijms24108469}, } @article{UBHD-68657955, author={Fresnais, Margaux and Longuespée, Rémi and Sauter, Max and Schaller, Torsten and Arndt, Michaela and Krauß, J{\"u}rgen and Blank, Antje and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Development and validation of an LC-MS-based quantification assay for new therapeutic antibodies}, subtitle={application to a novel therapy against herpes simplex virus}, year={2020}, pages={24329-24339}, language={eng}, issn={2470-1343}, volume={5}, number={38}, note={Gesehen am 05.11.2020}, journal={ACS omega}, doi={10.1021/acsomega.0c02547}, } @article{UBHD-68902200, author={Fresnais, Margaux and Karabulut, Seda and Abou Zeed, Yasmin and Ungermann, Johannes and Benzel, Julia and Pajtler, Kristian Wilfried and Pfister, Stefan and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Important requirements for the selection of internal standards during the development of desorption/ionization assays for drug quantification in biological matrices}, subtitle={a practical example}, year={2022}, pages={1-13}, language={eng}, issn={1420-3049}, volume={27}, note={Gesehen am 31.03.2022}, journal={Molecules}, doi={10.3390/molecules27030690}, } @article{UBHD-69057529, author={Fresnais, Margaux and Jung, Ina and Klein, Uli B. and Miller, Aubry K. and Turcan, S̨evin and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Important requirements for desorption/ionization mass spectrometric measurements of temozolomide-induced 2′-deoxyguanosine methylations in DNA}, year={2023}, pages={1-15}, language={eng}, issn={2072-6694}, volume={15}, note={Gesehen am 29.03.2023}, journal={Cancers}, doi={10.3390/cancers15030716}, keywords={Temozolomid}, } @article{UBHD-69112635, author={Fresnais, Margaux and Jung, Ina and Klein, Uli and Theile, Dirk and Liang, Siwen and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Quantification of biologically active DNA alkylation in temozolomide-exposed glioblastoma cell lines by ultra-performance liquid chromatography-tandem mass spectrometry}, subtitle={method development and recommendations for validation}, year={2023}, pages={23695-23705}, language={eng}, issn={2470-1343}, volume={8}, number={26}, note={Gesehen am 15.08.2023}, journal={ACS omega}, doi={10.1021/acsomega.3c01818}, } @article{UBHD-68639447, author={Fresnais, Margaux and Roth, André and Foerster, Kathrin and J{\"a}ger, Dirk and Pfister, Stefan and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Rapid and sensitive quantification of osimertinib in human plasma using a fully validated MALDI-IM-MS/MS assay}, year={2020}, pages={18 S.}, language={eng}, issn={2072-6694}, volume={12(2020}, note={Gesehen am 22.09.2020}, journal={Cancers}, doi={10.3390/cancers12071897}, } @article{UBHD-68565426, author={Fresnais, Margaux and Muck, Alexander and Majewsky, Marius and Pfister, Stefan and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Rapid and sensitive drug quantification in tissue sections using matrix assisted laser desorption Ionization-Ion mobility-mass spectrometry profiling}, year={2020}, pages={742-751}, language={eng}, issn={1879-1123}, volume={31}, number={3}, note={Gesehen am 16.04.2020}, journal={Journal of the American Society for Mass Spectrometry}, doi={10.1021/jasms.0c00005}, } @article{UBHD-68503743, author={Fresnais, Margaux and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Longuespée, Rémi}, title={Rapid drug detection in whole blood droplets using a desorption electrospray ionization static profiling approach - a proof-of-concept}, year={2020}, pages={6 S.}, language={eng}, issn={1097-0231}, volume={34 (2020}, note={Gesehen am 11.03.2020}, journal={Rapid communications in mass spectrometry}, doi={10.1002/rcm.8614}, url={https://doi.org/10.1002/rcm.8614}, library={UB}, } @article{UBHD-68727414, author={Fresnais, Margaux and Yildirim, Esra and Karabulut, Seda and J{\"a}ger, Dirk and Z{\"o}rnig, Inka and Benzel, Julia and Pajtler, Kristian Wilfried and Pfister, Stefan and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Longuespée, Rémi}, title={Rapid MALDI-MS assays for drug quantification in biological matrices}, subtitle={lessons learned, new developments, and future perspectives}, year={2021}, pages={1-19}, language={eng}, issn={1420-3049}, volume={26}, note={Gesehen am 04.08.2021}, journal={Molecules}, doi={10.3390/molecules26051281}, } @article{UBHD-68417547, author={Frindert, Jens and Zhang, Yaqing and N{\"u}bel, Gabriele and Hotz-Wagenblatt, Agnes and Burhenne, J{\"u}rgen and Haefeli, Walter E. and J{\"a}schke, Andres}, title={Identification, biosynthesis, and decapping of NAD-capped RNAs in B. subtilis}, year={2018}, pages={20 S.}, language={eng}, issn={2211-1247}, volume={24}, note={Gesehen am 07.08.2019}, journal={Cell reports}, doi={10.1016/j.celrep.2018.07.047}, } @article{UBHD-68739383, author={Fr{\"o}hlich, Margit and Hoffmann, Michael Marcus and Burhenne, J{\"u}rgen and Mikus, Gerd and Weiß, Johanna and Haefeli, Walter E.}, title={Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics}, year={2004}, pages={443-444}, language={eng}, issn={1365-2125}, volume={58}, number={4}, note={Gesehen am 19.05.2021}, journal={British journal of clinical pharmacology}, doi={10.1111/j.1365-2125.2004.02159.x}, } @article{UBHD-68740514, author={Fr{\"o}hlich, Margit and Burhenne, J{\"u}rgen and Martin-Facklam, Meret and Weiß, Johanna and Wolff, Michael von and Strowitzki, Thomas and Walter-Sack, Ingeborg and Haefeli, Walter E.}, title={Oral contraception does not alter single dose saquinavir pharmacokinetics in women}, year={2004}, pages={244-252}, language={eng}, issn={1365-2125}, volume={57}, number={3}, note={Gesehen am 25.05.2021}, journal={British journal of clinical pharmacology}, doi={10.1111/j.1365-2125.2003.01983.x}, } @article{UBHD-68255230, author={Fuchs, Ines Verena and Hafner-Blumenstiel, Verena and Markert, Christoph and Burhenne, J{\"u}rgen and Weiß, Johanna and Haefeli, Walter E. and Mikus, Gerd}, title={Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity}, year={2013}, pages={507-513}, language={eng}, issn={1432-1041}, volume={69}, number={3}, note={Published online: 12 September 2012 ; Gesehen am 28.05.2018}, journal={European journal of clinical pharmacology}, doi={10.1007/s00228-012-1388-1}, } @article{UBHD-68465199, author={Gade, Christina and Mikus, Gerd and Burhenne, J{\"u}rgen}, title={Higher chlorzoxazone clearance in obese children compared with nonobese peers}, year={2018}, pages={1738-1747}, language={eng}, issn={1365-2125}, volume={84}, number={8}, note={Gesehen am 09.12.2019}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.13602}, } @article{UBHD-68570512, author={Gade, Christina and Sverrisdóttir, Eva and Dalhoff, Kim and Sonne, Jesper and Johansen, Mia Østergaard and Christensen, Hanne Rolighed and Burhenne, J{\"u}rgen and Mikus, Gerd and Holm, Jens Christian and Lund, Trine Meldgaard and Holst, Helle}, title={Midazolam pharmacokinetics in obese and non-obese children and adolescents}, year={2020}, pages={643-654}, language={eng}, issn={1179-1926}, volume={59}, number={5}, note={Published online: 19 November 2019 ; Gesehen am 08.06.2020}, journal={Clinical pharmacokinetics}, doi={10.1007/s40262-019-00838-1}, } @article{UBHD-68378356, author={Gade, Christina and Mikus, Gerd and Burhenne, J{\"u}rgen}, title={Obesity-induced CYP2E1 activity in children}, year={2019}, pages={458-459}, language={eng}, issn={1365-2125}, volume={85}, number={2}, note={First published: 09 December 2018 ; Gesehen am 03.04.2019}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.13813}, } @article{UBHD-68437696, author={Geist, Marcus Julian Peter and Bardenheuer, Hubert J. and Burhenne, J{\"u}rgen and Mikus, Gerd}, title={Alteration of drug-metabolizing enzyme activity in palliative care patients}, subtitle={microdosed assessment of cytochrome P450 3A}, year={2019}, pages={850-855}, language={eng}, issn={1477-030X}, volume={33}, number={7}, note={Gesehen am 10.10.2019}, journal={Palliative medicine}, doi={10.1177/0269216319843629}, } @article{UBHD-68455880, author={Geist, Marcus Julian Peter and Siller, Nelly and Egerer, Gerlinde and Bardenheuer, Hubert J. and Burhenne, J{\"u}rgen and Mikus, Gerd}, title={Decreased Cytochrome P450 3A activity in palliative patients with haematological diseases}, subtitle={Potential impact on supportive drug therapies}, year={2019}, pages={117-122}, language={eng}, issn={1742-7843}, volume={125}, number={2}, note={Gesehen am 15.11.2019}, journal={Basic & clinical pharmacology & toxicology}, doi={10.1111/bcpt.13232}, } @article{UBHD-68466673, author={Geist, Marcus Julian Peter and Bardenheuer, Hubert J. and Burhenne, J{\"u}rgen and Mikus, Gerd}, title={In vivo CYP3A activity in palliative care patients}, subtitle={study protocol for a single arm prospective trial}, year={2018}, pages={686-688}, language={eng}, issn={1557-7740}, volume={21}, number={5}, note={Gesehen am 11.12.2019}, journal={Journal of palliative medicine}, doi={10.1089/jpm.2017.0461}, } @article{UBHD-68466345, author={Geist, Marcus Julian Peter and Ziesenitz, Victoria C. and Bardenheuer, Hubert J. and Burhenne, J{\"u}rgen and Skopp, Gisela and Mikus, Gerd}, title={Minor contribution of cytochrome P450 3A activity on fentanyl exposure in palliative care cancer patients}, year={2019}, pages={6 S.}, language={eng}, issn={2045-2322}, volume={9(2019) Artikel-Nummer 14635}, number={6 Seiten}, note={Gesehen am 10.12.2019}, journal={Scientific reports}, doi={10.1038/s41598-019-51279-6}, url={https://doi.org/10.1038/s41598-019-51279-6}, library={UB}, } @article{UBHD-68770183, author={Geist, Marcus Julian Peter and Egerer, Gerlinde and Burhenne, J{\"u}rgen and Mikus, Gerd}, title={Safety of voriconazole in a patient with CYP2C9*2/CYP2C9*2 genotype}, year={2006}, pages={3227-3228}, language={eng}, issn={1098-6596}, volume={50}, number={9}, note={Gesehen am 12.08.2021}, journal={Antimicrobial agents and chemotherapy}, doi={10.1128/AAC.00551-06}, } @article{UBHD-68688045, author={Geist, Marcus Julian Peter and Egerer, Gerlinde and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Weiß, Johanna and Mikus, Gerd}, title={Steady-state pharmacokinetics and metabolism of voriconazole in patients}, year={2013}, pages={2592-2599}, language={eng}, issn={1460-2091}, volume={68}, number={11}, note={Gesehen am 03.02.2020}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkt229}, } @article{UBHD-68819299, author={Grass, Jana and Rose, Peter and Burhenne, J{\"u}rgen and Blank, Antje and Haefeli, Walter E. and Mikus, Gerd}, title={Absolute bioavailability of microdosed midazolam after buccal administration is dependent on buccal exposure time}, year={2021}, pages={472-479}, language={eng}, issn={1552-4604}, volume={61}, number={4}, note={First published: 25 September 2020 ; Gesehen am 13.12.2021}, journal={Journal of clinical pharmacology}, doi={10.1002/jcph.1751}, url={https://doi.org/10.1002/jcph.1751}, library={UB}, } @article{UBHD-68685898, author={Gr{\"u}n, Barbara and Kießling, Michael and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Weiß, Johanna and Rauch, Geraldine and Haefeli, Walter E. and Czock, David}, title={Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters}, year={2013}, pages={787-796}, language={eng}, issn={1365-2125}, volume={76}, number={5}, note={Gesehen am 17.02.2021}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.12079}, } @article{UBHD-68264844, author={Gr{\"u}nig, Ekkehard and Ohnesorge, Johanna and Benjamin, Nicola and Burhenne, J{\"u}rgen and Enderle, Yeliz and Egenlauf, Benjamin and Fischer, Christine and Harutyunova, Satenik and Huppertz, Andrea and Haefeli, Walter E.}, title={Plasma drug concentrations in patients with pulmonary arterial hypertension on combination treatment}, year={2017}, pages={26-37}, language={eng}, issn={1423-0356}, volume={94}, number={1}, note={Gesehen am 25.06.2018}, journal={Respiration}, doi={10.1159/000470916}, } @article{UBHD-69187201, author={G{\"u}m{\"u}s, Katja S. and Teegelbekkers, Anna and Sauter, Max and Meid, Andreas and Burhenne, J{\"u}rgen and Weiß, Johanna and Blank, Antje and Haefeli, Walter E. and Czock, David}, title={Effect of tacrolimus formulation (prolonged-release vs immediate-release) on its susceptibility to drug-drug interactions with St. John's Wort}, year={2024}, pages={1-10}, language={eng}, issn={2160-7648}, volume={13}, note={Early view, first published: 04 January 2024 ; Gesehen am 29.02.2024}, journal={Clinical pharmacology in drug development}, doi={10.1002/cpdd.1364}, } @article{UBHD-68702074, author={Habtewold, Abiy and Makonnen, Eyasu and Amogne, Wondwossen and Yimer, Getnet and Aderaye, Getachew and Bertilsson, Leif and Burhenne, J{\"u}rgen and Aklillu, Eleni}, title={Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa?}, subtitle={the HIV-TB pharmagene study}, year={2015}, pages={1047-1064}, language={eng}, issn={1744-8042}, volume={16}, number={10}, note={Gesehen am 22.02.2021}, journal={Pharmacogenomics}, doi={10.2217/pgs.15.35}, } @article{UBHD-68946837, author={Habtewold, Abiy and Amogne, Wondwossen and Makonnen, Eyasu and Yimer, Getnet and Riedel, Klaus-Dieter and Ueda, Nobuhisa and Worku, Alemayehu and Haefeli, Walter E. and Lindquist, Lars and Aderaye, Getachew and Burhenne, J{\"u}rgen and Aklillu, Eleni}, title={Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients}, year={2011}, pages={2350-2361}, language={eng}, issn={1460-2091}, volume={66}, number={10}, note={Gesehen am 26.07.2022}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkr304}, } @article{UBHD-68199242, author={Habtewold, Abiy and Burhenne, J{\"u}rgen}, title={Long-term effect of rifampicin-based Anti-TB regimen coadministration on the pharmacokinetic parameters of efavirenz and 8-Hydroxy-Efavirenz in ethiopian patients}, year={2016}, pages={1538-1549}, language={eng}, issn={1552-4604}, volume={56}, number={12}, note={Gesehen am 07.12.2017}, journal={Journal of clinical pharmacology}, doi={10.1002/jcph.756}, } @article{UBHD-68687904, author={Habtewold, Abiy and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen}, title={Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients}, year={2013}, pages={484-489}, language={eng}, issn={1473-1150}, volume={13}, number={6}, note={Published: 23 October 2012 ; Gesehen am 09.02.2021}, journal={The pharmacogenomics journal}, doi={10.1038/tpj.2012.46}, } @article{UBHD-68305755, author={Habtewold, Abiy and Aklillu, Eleni and Burhenne, J{\"u}rgen}, title={Population pharmacokinetic model linking plasma and peripheral blood mononuclear cell concentrations of efavirenz and its metabolite, 8-hydroxy-efavirenz, in HIV Patients}, year={2017}, pages={13 S.}, language={eng}, issn={1098-6596}, volume={61(2017}, note={Gesehen am 18.09.2018}, journal={Antimicrobial agents and chemotherapy}, doi={10.1128/AAC.00207-17}, } @article{UBHD-69085964, author={Hafner-Blumenstiel, Verena and J{\"a}ger, M and Matthée, Anne-Kathrin and Ding, Reinhard and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Mikus, Gerd}, title={Effect of simultaneous induction and inhibition of CYP3A by St John's wort and ritonavir on CYP3A activity}, year={2010}, pages={191-196}, language={eng}, issn={1532-6535}, volume={87}, number={2}, note={Advance online publication 18 November 2009 ; Gesehen am 15.06.2023}, journal={Clinical pharmacology & therapeutics}, doi={10.1038/clpt.2009.206}, } @article{UBHD-69085974, author={Hafner-Blumenstiel, Verena and Czock, David and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Bommer, J{\"u}rgen and Mikus, Gerd and Machleidt, Christoph and Weinreich, Thomas and Haefeli, Walter E.}, title={Pharmacokinetics of sulfobutylether-beta-cyclodextrin and voriconazole in patients with end-stage renal failure during treatment with two hemodialysis systems and hemodiafiltration}, year={2010}, pages={2596-2602}, language={eng}, issn={1098-6596}, volume={54}, number={6}, note={Gesehen am 15.06.2023}, journal={Antimicrobial agents and chemotherapy}, doi={10.1128/aac.01540-09}, } @article{UBHD-68702713, author={Halama, Birte and Hohmann, Nicolas and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions}, year={2013}, pages={564-571}, language={eng}, issn={1532-6535}, volume={93}, number={6}, note={Gesehen am 13.10.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1038/clpt.2013.27}, } @article{UBHD-68295329, author={Harnoß, Jonathan M. and Platzer, Lisa K. and Burhenne, J{\"u}rgen and Radhakrishnan, Praveen and Cai, Jun and Strowitzki, Moritz and Weiß, Johanna and Ritter, Alina and Mollenhauer, Martin and Ulrich, Alexis and Haefeli, Walter E. and Schneider, Martin}, editor={Schmidt, Thomas}, title={Prolyl hydroxylase inhibition enhances liver regeneration without induction of tumor growth}, year={2017}, pages={782-791}, language={eng}, issn={1528-1140}, volume={265}, number={4}, note={Gesehen am 14.08.2018}, journal={Annals of surgery}, doi={10.1097/SLA.0000000000001696}, } @article{UBHD-68959098, author={Hassan, Arwa and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E. and Czock, David}, title={Modulators of very low voriconazole concentrations in routine therapeutic drug monitoring}, year={2011}, pages={86-93}, language={eng}, issn={1536-3694}, volume={33}, number={1}, note={Gesehen am 31.08.2022}, journal={Therapeutic drug monitoring}, doi={10.1097/FTD.0b013e31820530cd}, } @article{UBHD-68738272, author={Hesse, Christiane and Siedler, Heike and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Haefeli, Walter E.}, title={Fluvoxamine affects sildenafil kinetics and dynamics}, year={2005}, pages={589-592}, language={eng}, issn={1533-712X}, volume={25}, number={6}, note={Gesehen am 17.05.2021}, journal={Journal of clinical psychopharmacology}, doi={10.1097/01.jcp.0000186866.82665.29}, } @article{UBHD-68297425, author={Hohmann, Nicolas and Kreuter, Rebecca and Blank, Antje and Weiß, Johanna and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Mikus, Gerd}, title={Autoinhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics}, year={2017}, pages={1954-1965}, language={eng}, issn={1365-2125}, volume={83}, number={9}, note={Gesehen am 21.08.2018}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.13297}, } @article{UBHD-68069516, author={Hohmann, Nicolas and Kocheise, Franziska and Carls, Alexandra and Burhenne, J{\"u}rgen and Weiß, Johanna and Haefeli, Walter E. and Mikus, Gerd}, title={Dose-dependent bioavailability and CYP3A inhibition contribute to non-linear pharmacokinetics of voriconazole}, year={2016}, pages={1535-1545}, language={eng}, issn={1179-1926}, volume={55}, number={12}, note={Gesehen am 05.01.2017}, journal={Clinical pharmacokinetics}, doi={10.1007/s40262-016-0416-1}, } @article{UBHD-69320525, author={Hohmann, Nicolas and Friedrichs, Anna S. and Burhenne, J{\"u}rgen and Blank, Antje and Mikus, Gerd and Haefeli, Walter E.}, title={Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin}, year={2024}, pages={1-11}, language={eng}, issn={1752-8062}, volume={17}, note={Erste Ver{\"o}ffentlichung: 16. August 2024 ; Gesehen am 20.03.2025}, journal={Clinical and translational science}, doi={10.1111/cts.70007}, } @article{UBHD-68635189, author={Hohmann, Nicolas and Kocheise, Franziska and Carls, Alexandra and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Mikus, Gerd}, title={Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans}, year={2015}, pages={278-285}, language={eng}, issn={1365-2125}, volume={79}, number={2}, note={Accepted article published online 2 September 2014 ; Gesehen am 07.09.2020}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.12502}, } @article{UBHD-68772058, author={Hohmann, Nicolas and Bozorgmehr, Farastuk and Christopoulos, Petros and Mikus, Gerd and Blank, Antje and Burhenne, J{\"u}rgen and Thomas, Michael and Haefeli, Walter E.}, title={Pharmacoenhancement of low crizotinib plasma concentrations in patients with anaplastic lymphoma kinase-positive non-small cell lung cancer using the CYP3A inhibitor cobicistat}, year={2021}, pages={487-491}, language={eng}, issn={1752-8062}, volume={14}, number={2}, note={First published: 22 November 2020 ; Gesehen am 19.08.2021}, journal={Clinical and translational science}, doi={10.1111/cts.12921}, url={https://doi.org/10.1111/cts.12921}, library={UB}, } @article{UBHD-68069519, author={Hohmann, Nicolas and Reinhard, Raphael and Schnaidt, Sven and Witt, Lukas and Carls, Alexandra and Burhenne, J{\"u}rgen and Mikus, Gerd and Haefeli, Walter E.}, title={Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans}, year={2016}, pages={2241-2247}, language={eng}, issn={1460-2091}, volume={71}, number={8}, note={Gesehen am 05.01.2017}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkw125}, } @article{UBHD-69320509, author={Hose, Dirk and Ray, Seemun and R{\"o}ßler, Sina and Thormann, Ulrich and Schnettler, Reinhard and De Veirman, Kim and Khassawna, Thaqif el- and Heiss, Christian and Hild, Anne and Zahner, Daniel and Alagboso, Francisca and Henss, Anja and Beck, Susanne and Emde-Rajaratnam, Martina and Burhenne, J{\"u}rgen and Bamberger, Juliane and Menu, Eline and de Bruyne, Elke and Gelinsky, Michael and Kampschulte, Marian and Rohnke, Marcus and Wenisch, Sabine and Vanderkerken, Karin and Hanke, Thomas and Seckinger, Anja and Alt, Volker}, title={Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma}, year={2024}, pages={1-20}, language={eng}, issn={1756-8722}, volume={17}, number={Artikel-ID 128}, note={Gesehen am 20.03.2025}, journal={Journal of hematology & oncology}, doi={10.1186/s13045-024-01636-4}, } @article{UBHD-69320511, author={Hose, Dirk and Ray, Seemun and R{\"o}ßler, Sina and Thormann, Ulrich and Schnettler, Reinhard and De Veirman, Kim and Khassawna, Thaqif el- and Heiss, Christian and Hild, Anne and Zahner, Daniel and Alagboso, Francisca and Henss, Anja and Beck, Susanne and Emde-Rajaratnam, Martina and Burhenne, J{\"u}rgen and Bamberger, Juliane and Menu, Eline and de Bruyne, Elke and Gelinsky, Michael and Kampschulte, Marian and Rohnke, Marcus and Wenisch, Sabine and Vanderkerken, Karin and Hanke, Thomas and Seckinger, Anja and Alt, Volker}, title={Correction: Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma}, year={2025}, pages={1}, language={eng}, issn={1756-8722}, volume={18}, number={Artikel-ID 11}, note={Gesehen am 20.03.2025}, journal={Journal of hematology & oncology}, doi={10.1186/s13045-025-01663-9}, } @article{UBHD-69120787, author={Huppertz, Andrea and Bollmann, Johanna and Behnisch, Rouven and Bruckner, Thomas and Zorn, Markus and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Czock, David}, title={Differential effect of a continental breakfast on tacrolimus formulations with different release characteristics}, year={2021}, pages={899-907}, language={eng}, issn={2160-7648}, volume={10}, number={8}, note={Gesehen am 11.09.2023}, journal={Clinical pharmacology in drug development}, doi={10.1002/cpdd.924}, url={https://doi.org/10.1002/cpdd.924}, library={UB}, } @article{UBHD-68479262, author={Huppertz, Andrea and Werntz, Lars and Meid, Andreas and Foerster, Kathrin and Burhenne, J{\"u}rgen and Czock, David and Mikus, Gerd and Haefeli, Walter E.}, title={Rivaroxaban and macitentan can be coadministered without dose adjustment but the combination of rivaroxaban and St John's wort should be avoided}, year={2018}, pages={2903-2913}, language={eng}, issn={1365-2125}, volume={84}, number={12}, note={Gesehen am 22.01.2020}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.13757}, } @article{UBHD-68564423, author={Huppertz, Andrea and Grond-Ginsbach, Caspar and Dumschat, Chris and Foerster, Kathrin and Burhenne, J{\"u}rgen and Weiß, Johanna and Czock, David and Purrucker, Jan and Rizos, Timolaos and Haefeli, Walter E.}, title={Unexpected excessive apixaban exposure}, subtitle={case report of a patient with polymorphisms of multiple apixaban elimination pathways}, year={2019}, pages={6 S.}, language={eng}, issn={2050-6511}, volume={20(2019}, note={Gesehen am 15.04.2020}, journal={BMC pharmacology & toxicology}, doi={10.1186/s40360-019-0331-9}, } @article{UBHD-68637055, author={Jedamzik, Julia and M{\"u}hlbacher, J. and Fitschek, F. and Schwarz, C. and Burhenne, J{\"u}rgen and Asenbaum, U. and Kaczirek, K. and Mikus, Gerd}, title={No alteration of Cyp3A4 activity after major hepatectomy in the early postoperative period}, subtitle={a prospective before-after study}, year={2020}, pages={131-135}, language={eng}, issn={1743-9159}, volume={79}, note={Gesehen am 14.09.2020}, journal={International journal of surgery}, doi={10.1016/j.ijsu.2020.05.010}, } @article{UBHD-68737224, author={Josephson, Filip and Allqvist, A. and Janabi, M. and Sayi, J. and Aklillu, Eleni and Jande, M. and Mahindi, M. and Burhenne, J{\"u}rgen and Bottiger, Y. and Gustafsson, L. L. and Haefeli, Walter E. and Bertilsson, L.}, title={CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir}, year={2007}, pages={708-712}, language={eng}, issn={1532-6535}, volume={81}, number={5}, note={Gesehen am 12.05.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1038/sj.clpt.6100117}, } @article{UBHD-69049277, author={Kaiser, Stefanie and Burhenne, J{\"u}rgen and Helm, Mark}, title={Detection of RNA modifications}, year={2010}, pages={237-247}, language={eng}, issn={1555-8584}, volume={7}, number={2 vom: M{\"a}rz/Apr.}, note={Gesehen am 08.03.2023}, journal={RNA biology}, doi={10.4161/rna.7.2.11468}, } @article{UBHD-68947827, author={Kaiser, Stefanie and Seidu-Larry, Salifu and Burhenne, J{\"u}rgen and Motorin, Yuri and Helm, Mark}, title={A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA}, year={2011}, pages={7348-7360}, language={eng}, issn={1362-4962}, volume={39}, number={16}, note={Gesehen am 28.07.2022}, journal={Nucleic acids research}, doi={10.1093/nar/gkr449}, } @article{UBHD-68946153, author={Katzenmaier, Stephanie Katharina and Markert, Christoph and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Mikus, Gerd}, title={Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using a limited sampling strategy}, year={2011}, pages={666-673}, language={eng}, issn={1532-6535}, volume={90}, number={5}, note={Gesehen am 25.07.2022}, journal={Clinical pharmacology & therapeutics}, doi={10.1038/clpt.2011.164}, } @article{UBHD-68809783, author={Kees, Frieder and Bucher, Michael and Schweda, Frank and Gschaidmeier, Harald and Burhenne, J{\"u}rgen and Mikus, Gerd and Faerber, Lothar}, title={Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers}, year={2006}, pages={312-320}, language={eng}, issn={1536-3694}, volume={28}, number={3}, journal={Therapeutic drug monitoring}, doi={10.1097/01.ftd.0000211804.89440.74}, } @article{UBHD-68295296, author={Keubler, Anja and Weiß, Johanna and Haefeli, Walter E. and Mikus, Gerd and Burhenne, J{\"u}rgen}, title={Drug interaction of efavirenz and midazolam}, subtitle={efavirenz activates the CYP3A-mediated midazolam 1′-Hydroxylation in vitro}, year={2012}, pages={1178-1182}, language={eng}, issn={1521-009X}, volume={40}, number={6}, note={Published online May 16, 2012 ; Gesehen am 14.08.2018}, journal={Drug metabolism and disposition}, doi={10.1124/dmd.111.043844}, } @article{UBHD-68399211, author={Kiene, Klara and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Mikus, Gerd}, title={Microdosed midazolam for the determination of cytochrome P450 3A activity}, subtitle={Development and clinical evaluation of a buccal film}, year={2019}, pages={77-82}, language={eng}, issn={1879-0720}, volume={135}, note={Gesehen am 17.06.2019}, journal={European journal of pharmaceutical sciences}, doi={10.1016/j.ejps.2019.05.010}, } @article{UBHD-68923696, author={Kraft, Manuel and Foerster, Kathrin and Wiedmann, Felix Tobias and Sauter, Max and Paasche, Amelie and Blochberger, Pablo L. and Yesilg{\"o}z, Baran and L'Hoste, Yannick and Frey, Norbert and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Schmidt, Constanze}, title={Simultaneous quantification and pharmacokinetic characterization of doxapram and 2-ketodoxapram in porcine plasma and brain tissue}, year={2022}, pages={1-13}, language={eng}, issn={1999-4923}, volume={14}, note={This article belongs to the Section "Pharmacokinetics and Pharmacodynamics" ; Gesehen am 30.05.2022}, journal={Pharmaceutics}, doi={10.3390/pharmaceutics14040762}, } @article{UBHD-69187437, author={Krohmer, Evelyn and Rohr, Brit Silja and Stoll, Felicitas E. and G{\"u}m{\"u}s, Katja S. and Bergamino, Mariano and Mikus, Gerd and Sauter, Max and Burhenne, J{\"u}rgen and Weiß, Johanna and Meid, Andreas and Czock, David and Blank, Antje and Haefeli, Walter E.}, title={Influence of a short course of ritonavir used as booster in antiviral therapies against SARS-CoV-2 on the exposure of atorvastatin and rosuvastatin}, year={2025}, pages={325–335}, language={eng}, issn={1573-7241}, volume={39}, note={Ver{\"o}ffentlicht online: 19 December 2023 ; Gesehen am 01.03.2024}, journal={Cardiovascular drugs and therapy}, doi={10.1007/s10557-023-07538-w}, } @article{UBHD-68778487, author={Linde, Teresa von and Bajraktari-Sylejmani, Gzona and Haefeli, Walter E. and Burhenne, J{\"u}rgen and Weiß, Johanna and Sauter, Max}, title={Rapid and sensitive quantification of intracellular glycyl-sarcosine for semi-high-throughput screening for inhibitors of PEPT-1}, year={2021}, pages={1-12}, language={eng}, issn={1999-4923}, volume={13}, note={Gesehen am 09.09.2021}, journal={Pharmaceutics}, doi={10.3390/pharmaceutics13071019}, } @article{UBHD-68620670, author={Liu, Lu and Milde, Till and Haefeli, Walter E. and Witt, Olaf and Burhenne, J{\"u}rgen}, title={Quantification of vorinostat and its main metabolites in plasma and intracellular vorinostat in PBMCs by liquid chromatography coupled to tandem mass spectrometry and its relation to histone deacetylase activity in human blood}, year={2014}, pages={212-221}, language={eng}, issn={1873-376X}, volume={964}, note={Gesehen am 24.07.2020}, journal={Journal of chromatography}, doi={10.1016/j.jchromb.2014.02.014}, } @article{UBHD-68819343, author={Longuespée, Rémi and Theile, Dirk and Fresnais, Margaux and Burhenne, J{\"u}rgen and Weiß, Johanna and Haefeli, Walter E.}, title={Approaching sites of action of drugs in clinical pharmacology}, subtitle={New analytical options and their challenges}, year={2021}, pages={858-874}, language={eng}, issn={1365-2125}, volume={87}, number={3}, note={First published: 02 September 2020 ; Gesehen am 13.12.2021}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.14543}, url={https://doi.org/10.1111/bcp.14543}, library={UB}, } @article{UBHD-69177867, author={Longuespée, Rémi and Kunz, Julia and Fresnais, Margaux and Foerster, Kathrin and Burhenne, J{\"u}rgen and Thomas, Michael and Kazdal, Daniel and Stenzinger, Albrecht and Christopoulos, Petros and Haefeli, Walter E.}, title={Therapeutic drug monitoring of osimertinib in non-small cell lung cancer and short bowel syndrome}, subtitle={a case report}, year={2024}, pages={344-349}, language={eng}, issn={1365-2125}, volume={90}, number={1}, note={Erstver{\"o}ffentlichung: 10. Oktober 2023 ; Gesehen am 06.02.2024}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.15924}, } @article{UBHD-68781162, author={Mahmoudi, Mazyar and Foerster, Kathrin and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={Application of microdosed intravenous omeprazole to determine hepatic CYP2C19 activity}, year={2021}, pages={789-798}, language={eng}, issn={1552-4604}, volume={61}, number={6}, note={First published: 25 November 2020 ; Gesehen am 18.09.2021}, journal={Journal of clinical pharmacology}, doi={10.1002/jcph.1789}, url={https://doi.org/10.1002/jcph.1789}, library={UB}, } @article{UBHD-68430333, author={Mahmoudi, Mazyar and Brenner, Thorsten and Hatiboglu, Gencay and Burhenne, J{\"u}rgen and Weiß, Johanna and Weigand, Markus A. and Haefeli, Walter E.}, title={Reply to Truffot et al}, year={2018}, pages={1644-1646}, language={eng}, issn={1537-6591}, volume={66}, number={10}, note={Published: 27 January 2018 ; Reaktion auf: Truffot, A., Thiebaut-Bertrand, A., Chapuis, C., Stanke-Labesque, F., Gautier-Veyret, E.: Inhibition of voriconazole metabolism by meropenem: a role for inflammation? ; Gesehen am 16.09.2019}, journal={Clinical infectious diseases}, doi={10.1093/cid/cix1099}, } @article{UBHD-68294403, author={Mahmoudi, Mazyar and Brenner, Thorsten and Hatiboglu, Gencay and Burhenne, J{\"u}rgen and Weiß, Johanna and Weigand, Markus A. and Haefeli, Walter E.}, title={Substantial impairment of voriconazole clearance by high-dose meropenem in a patient with renal failure}, year={2017}, pages={1033-1036}, language={eng}, issn={1537-6591}, volume={65}, number={6}, note={Gesehen am 10.08.2018}, journal={Clinical infectious diseases}, doi={10.1093/cid/cix443}, } @article{UBHD-68301534, author={Majewsky, Marius and Johann, Pascal-David and Jones, David T. W. and Pfister, Stefan and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS}, year={2018}, pages={151-158}, language={eng}, issn={1873-264X}, volume={151}, note={available online 28 December 2017 ; Gesehen am 03.09.2018}, journal={Journal of pharmaceutical and biomedical analysis}, doi={10.1016/j.jpba.2017.12.056}, } @article{UBHD-67777493, author={Markert, Christoph and Schweizer, Yvonne and Hellwig, Regina and Wirsching, Theresia and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers}, year={2014}, pages={141-148}, language={eng}, issn={1365-2125}, volume={77}, number={1}, note={Gesehen am 23.02.2015}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.12177}, } @article{UBHD-67777495, author={Markert, Christoph and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={CYP2C9 polymorphism is not a major determinant of bosentan exposure in healthy volunteers}, year={2014}, pages={250-251}, language={eng}, issn={1532-6535}, volume={95}, number={3}, note={Gesehen am 23.02.2015}, journal={Clinical pharmacology & therapeutics}, doi={10.1038/clpt.2013.188}, } @article{UBHD-68135068, author={Markert, Christoph and Kastner, Ida Maria and Hellwig, Regina and Schweizer, Yvonne and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={The effect of induction of CYP3A4 by St John's Wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype}, year={2015}, pages={423-428}, language={eng}, issn={1742-7843}, volume={116}, number={5}, note={First published: 8 November 2014 ; Gesehen am 06.07.2017}, journal={Basic & clinical pharmacology & toxicology}, doi={10.1111/bcpt.12332}, } @article{UBHD-68641508, author={Markert, Christoph and Ngui, Prisca and Hellwig, Regina and Wirsching, Theresia and Kastner, Ida Maria and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={Influence of St. John’s wort on the steadystate pharmacokinetics and metabolism of bosentan}, year={2014}, pages={328-336}, language={eng}, volume={52}, number={04}, note={Gesehen am 30.09.2020}, journal={International journal of clinical pharmacology and therapeutics}, doi={10.5414/CP202048}, } @article{UBHD-68751893, author={Markert, Christoph and Hellwig, Regina and Burhenne, J{\"u}rgen and Hoffmann, Michael Marcus and Weiß, Johanna and Mikus, Gerd and Haefeli, Walter E.}, title={Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1}, year={2013}, pages={1785-1793}, language={eng}, issn={1432-1041}, volume={69}, number={10}, note={Gesehen am 23.06.2021}, journal={European journal of clinical pharmacology}, doi={10.1007/s00228-013-1529-1}, } @article{UBHD-68630935, author={Markert, Christoph and Wirsching, Theresia and Hellwig, Regina and Burhenne, J{\"u}rgen and Weiß, Johanna and Riedel, Klaus-Dieter and Mikus, Gerd and Haefeli, Walter E.}, title={Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults}, year={2014}, pages={957-964}, language={eng}, volume={52}, number={11}, note={Gesehen am 25.08.2020}, journal={International journal of clinical pharmacology and therapeutics}, doi={10.5414/CP202164}, } @article{UBHD-68739385, author={Martin-Facklam, Meret and Rieger, Karin and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Walter-Sack, Ingeborg and Haefeli, Walter E.}, title={Undeclared exposure to St. John's Wort in hospitalized patients}, year={2004}, pages={437-441}, language={eng}, issn={1365-2125}, volume={58}, number={4}, note={Gesehen am 19.05.2021}, journal={British journal of clinical pharmacology}, doi={10.1111/j.1365-2125.2004.02169.x}, } @article{UBHD-68796761, author={Meissner, Peter and Mandi, Germain and Witte, Steffen and Coulibaly, Boubacar and Mansmann, Ulrich and Rengelshausen, Jens and Schiek, Wolfgang and Jahn, Albrecht and Sanon, Mamadou and Tapsoba, Théophile and Walter-Sack, Ingeborg and Mikus, Gerd and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Schirmer, Heiner and Kouyaté, Bocar and M{\"u}ller, Olaf}, title={Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841]}, year={2005}, pages={9 S.}, language={eng}, issn={1475-2875}, volume={4}, number={Artikel-ID 45}, note={Gesehen am 04.11.2021}, journal={Malaria journal}, doi={10.1186/1475-2875-4-45}, } @article{UBHD-68864494, author={Mikus, Gerd and Foerster, Kathrin and Schaum{\"a}ker, Marlene and Lehmann, Marie-Louise and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug-drug interactions with different perpetrator drugs}, year={2020}, pages={1632-1641}, language={eng}, issn={1365-2125}, volume={86}, number={8}, note={First published: 11 March 2020 ; Gesehen am 11.01.2022}, journal={British journal of clinical pharmacology}, doi={10.1111/bcp.14277}, url={https://doi.org/10.1111/bcp.14277}, library={UB}, } @article{UBHD-68323655, author={Mikus, Gerd and Heinrich, Tilman and B{\"o}digheimer, Julia and R{\"o}der, Claudia Stephanie and Matthée, Anne-Kathrin and Weiß, Johanna and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Semisimultaneous midazolam administration to evaluate the time course of CYP3A activation by a single oral dose of efavirenz}, year={2017}, pages={899-905}, language={eng}, issn={1552-4604}, volume={57}, number={7}, note={Gesehen am 31.10.2018}, journal={Journal of clinical pharmacology}, doi={10.1002/jcph.879}, } @article{UBHD-68738192, author={Mikus, Gerd and Sch{\"o}wel, Verena Jennifer Johanna and Ten Hoevel, Magdalena Maria and Rengelshausen, Jens and Ding, Reinhard and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Weiß, Johanna and Thomsen, Torben and Haefeli, Walter E.}, title={Potent cytochrome P450 2C19 genotype-related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir}, year={2006}, pages={126-135}, language={eng}, issn={1532-6535}, volume={80}, number={2}, note={Gesehen am 17.05.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1016/j.clpt.2006.04.004}, } @article{UBHD-68739362, author={Mikus, Gerd and Schmidt, Laila Diana and Burhenne, J{\"u}rgen and Ding, Reinhard and Riedel, Klaus-Dieter and Tayrouz Haffar, Yorki Antoine and Weiß, Johanna and Haefeli, Walter E.}, title={Reduction of saquinavir exposure by coadministration of loperamide}, year={2004}, pages={1015-1024}, language={eng}, issn={1179-1926}, volume={43}, number={14}, note={Published: 30 September 2012 ; Elektronische Reproduktion der Druck-Ausgabe ; Gesehen am 19.05.2021}, journal={Clinical pharmacokinetics}, doi={10.2165/00003088-200443140-00004}, } @article{UBHD-68244730, author={Moj, Daniel and Burhenne, J{\"u}rgen and Egerer, Gerlinde and Haefeli, Walter E.}, title={A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model of the histone deacetylase (HDAC) inhibitor vorinostat for pediatric and adult patients and its application for dose specification}, year={2017}, pages={1013–1026}, language={eng}, issn={1432-0843}, volume={80}, number={5}, note={Gesehen am 19.04.2018}, journal={Cancer chemotherapy and pharmacology}, doi={10.1007/s00280-017-3447-x}, } @article{UBHD-68962151, author={Motorin, Yuri and Burhenne, J{\"u}rgen and Teimer, Roman and Koynov, Kaloian and Willnow, Sophie and Weinhold, Elmar and Helm, Mark}, title={Expanding the chemical scope of RNA}, subtitle={methyltransferases to site-specific alkynylation of RNA for click labeling}, year={2011}, pages={1943-1952}, language={eng}, issn={1362-4962}, volume={39}, number={5}, note={First published online: 30 October 2010 ; Gesehen am 08.09.2022}, journal={Nucleic acids research}, doi={10.1093/nar/gkq825}, } @article{UBHD-68561496, author={Mugusi, Sabina and Habtewold, Abiy and Ngaimisi, Eliford and Amogne, Wondwossen and Yimer, Getnet and Minzi, Omary and Makonnen, Eyasu and Sudfeld, Christopher and Burhenne, J{\"u}rgen and Aklillu, Eleni}, title={Impact of population and pharmacogenetics variations on efavirenz pharmacokinetics and immunologic outcomes during anti-tuberculosis co-therapy}, subtitle={a parallel prospective cohort study in two sub-Sahara African populations}, year={2020}, pages={13 S.}, language={eng}, issn={1663-9812}, volume={11(2020) Artikel-Nummer 26}, number={13 Seiten}, note={Gesehen am 03.04.2020}, journal={Frontiers in pharmacology}, doi={10.3389/fphar.2020.00026}, } @article{UBHD-68297917, author={Mugusi, Sabina and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen}, title={Liver enzyme abnormalities and associated risk factors in HIV patients on Efavirenz-Based HAART with or without tuberculosis co-infection in Tanzania}, year={2012}, pages={9 S.}, language={eng}, issn={1932-6203}, volume={7(2012}, note={Gesehen am 22.08.2018}, journal={PLOS ONE}, doi={10.1371/journal.pone.0040180}, } @article{UBHD-68393091, author={Mugusi, Sabina and Burhenne, J{\"u}rgen}, title={Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin}, year={2018}, pages={1405-1415}, language={eng}, issn={1432-1041}, volume={74}, number={11}, note={Gesehen am 27.05.2019}, journal={European journal of clinical pharmacology}, doi={10.1007/s00228-018-2499-0}, } @article{UBHD-68966560, author={Ngaimisi, Eliford and Mugusi, S. and Minzi, O. and Sasi, P. and Riedel, Klaus-Dieter and Suda, A. and Ueda, N. and Janabi, M. and Mugusi, F. and Haefeli, Walter E. and Bertilsson, L. and Burhenne, J{\"u}rgen and Aklillu, E.}, title={Effect of rifampicin and CYP2B6 genotype on long-term efavirenz autoinduction and plasma exposure in HIV patients with or without tuberculosis}, year={2011}, pages={406-413}, language={eng}, issn={1532-6535}, volume={90}, number={3 vom: Sept.}, note={Gesehen am 22.09.2022}, journal={Clinical pharmacology & therapeutics}, doi={10.1038/clpt.2011.129}, } @article{UBHD-68803768, author={Ngaimisi, Eliford and Habtewold, Abiy and Minzi, Omary and Makonnen, Eyasu and Mugusi, Sabina and Amogne, Wondwossen and Yimer, Getnet and Riedel, Klaus-Dieter and Janabi, Mohammed and Aderaye, Getachew and Mugusi, Ferdinand and Bertilsson, Leif and Aklillu, Eleni and Burhenne, J{\"u}rgen}, title={Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes}, subtitle={a parallel-group prospective cohort study in two sub-Saharan Africa populations}, year={2013}, pages={1-13}, language={eng}, issn={1932-6203}, volume={8}, note={Gesehen am 22.11.2021}, journal={PLOS ONE}, doi={10.1371/journal.pone.0067946}, } @article{UBHD-68444895, author={Ngaimisi, Eliford and Burhenne, J{\"u}rgen}, title={Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype}, year={2018}, pages={12 S.}, language={eng}, issn={2045-2322}, volume={8(2018) Artikel-Nummer 16316}, number={12 Seiten}, note={Gesehen am 24.10.2019}, journal={Scientific reports}, doi={10.1038/s41598-018-34674-3}, } @article{UBHD-68655333, author={Ngaimisi, Eliford and Burhenne, J{\"u}rgen}, title={Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment}, year={2014}, pages={3311-3319}, language={eng}, issn={1460-2091}, volume={69}, number={12}, note={Gesehen am 29.10.2020}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dku286}, } @article{UBHD-68613249, author={Nylén, Hanna and Habtewold, Abiy and Makonnen, Eyasu and Yimer, Getnet and Bertilsson, Leif and Burhenne, J{\"u}rgen and Diczfalusy, Ulf and Aklillu, Eleni}, title={Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency}, subtitle={a prospective cohort study}, year={2016}, language={eng}, issn={1536-5964}, volume={95(2016}, note={Gesehen am 03.07.2020}, journal={Medicine}, doi={10.1097/MD.0000000000004631}, } @article{UBHD-68494516, author={Paleari, Laura and Burhenne, J{\"u}rgen and Weiß, Johanna and Foersch, Sebastian and Roth, Wilfried and Parodi, Andrea and Gnant, Michael and Bachleitner-Hofmann, Thomas and Scherer, Dominique and Ulrich, Cornelia and Stabuc, Borut and Puntoni, Matteo and Coccia, Gianni and Petrera, Marilena and Haefeli, Walter E. and DeCensi, Andrea}, title={High accumulation of metformin in colonic tissue of subjects with diabetes or the metabolic syndrome}, year={2018}, pages={1543-1545}, language={eng}, issn={1528-0012}, volume={154}, number={5}, note={Letter ; Gesehen am 27.02.2020}, journal={Gastroenterology}, doi={10.1053/j.gastro.2017.12.040}, } @article{UBHD-68771331, author={Rengelshausen, Jens and G{\"o}ggelmann, Christoph and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Ludwig, Jochen and Weiß, Johanna and Mikus, Gerd and Walter-Sack, Ingeborg and Haefeli, Walter E.}, title={Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction}, year={2003}, pages={32-38}, language={eng}, issn={1365-2125}, volume={56}, number={1 vom: Juli}, note={Gesehen am 17.08.2021}, journal={British journal of clinical pharmacology}, doi={10.1046/j.1365-2125.2003.01824.x}, } @article{UBHD-68738866, author={Rengelshausen, Jens and Banfield, Maria and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Weiß, Johanna and Thomsen, Torben and Walter-Sack, Ingeborg and Haefeli, Walter E. and Mikus, Gerd}, title={Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics}, year={2005}, pages={25-33}, language={eng}, issn={1532-6535}, volume={78}, number={1}, note={Gesehen am 18.05.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1016/j.clpt.2005.01.024}, } @article{UBHD-68738888, author={Rengelshausen, Jens and Burhenne, J{\"u}rgen and Fr{\"o}hlich, Margit and Tayrouz Haffar, Yorki Antoine and Singh, Shio Kumar and Riedel, Klaus-Dieter and M{\"u}ller, Olaf and Hoppe-Tichy, Torsten and Haefeli, Walter E. and Mikus, Gerd and Walter-Sack, Ingeborg}, title={Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria}, year={2004}, pages={709-715}, language={eng}, issn={1432-1041}, volume={60}, number={10}, note={Gesehen am 18.05.2021}, journal={European journal of clinical pharmacology}, doi={10.1007/s00228-004-0818-0}, } @article{UBHD-68638234, author={Rettig, Inga Edeltraud and Koeneke, Emily and Trippel, Franziska and Mueller, Wolf C. and Burhenne, J{\"u}rgen and Kopp-Schneider, Annette and Fabian, Johannes and Schober, Andreas and Fernekorn, Uta and Deimling, Andreas von and Deubzer, Hedwig and Milde, Till and Witt, Olaf and Oehme, Ina}, title={Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation}, year={2015}, pages={14 S.}, language={eng}, issn={2041-4889}, volume={Bd. 6}, journal={Cell death & disease}, doi={10.1038/cddis.2015.24}, } @article{UBHD-68739359, author={Riedel, Klaus-Dieter and Rieger, Karin and Martin-Facklam, Meret and Mikus, Gerd and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Simultaneous determination of hypericin and hyperforin in human plasma with liquid chromatography-tandem mass spectrometry}, year={2004}, pages={27-33}, language={eng}, issn={1873-376X}, volume={813}, number={1-2}, note={Gesehen am 19.05.2021}, journal={Journal of chromatography}, doi={10.1016/j.jchromb.2004.09.061}, } @article{UBHD-69252563, author={Rigalli, Juan Pablo and Gagliardi, Anna and Diester, Klara and Bajraktari-Sylejmani, Gzona and Blank, Antje and Burhenne, J{\"u}rgen and Lenard, Alexander and Werntz, Lars and Huppertz, Andrea and M{\"u}nch, Lena and Wendt, Janica Margrit and Sauter, Max and Haefeli, Walter E. and Weiß, Johanna}, title={Extracellular vesicles as surrogates for the regulation of the drug transporters ABCC2 (MRP2) and ABCG2 (BCRP)}, year={2024}, pages={1-18}, language={eng}, issn={1422-0067 and 1661-6596}, volume={25}, note={Gesehen am 11.09.2024}, journal={International journal of molecular sciences}, doi={10.3390/ijms25074118}, } @article{UBHD-68932820, author={Rizos, Timolaos and Meid, Andreas and Huppertz, Andrea and Dumschat, Chris and Purrucker, Jan and Foerster, Kathrin and Burhenne, J{\"u}rgen and Czock, David and Jenetzky, Ekkehart and Ringleb, Peter A. and Haefeli, Walter E.}, title={Low exposure to direct oral anticoagulants is associated with ischemic stroke and its severity}, year={2022}, pages={17 S.}, language={eng}, issn={2287-6405}, volume={24}, note={Mit erg{\"a}nzenden Materialien f{\"u}r diesen Artikel ; Gesehen am 21.06.2022}, journal={Journal of stroke}, doi={10.5853/jos.2020.04952}, } @article{UBHD-69001651, author={Rohr, Brit Silja and Foerster, Kathrin and Blank, Antje and Burhenne, J{\"u}rgen and Mahmoudi, Mazyar and Haefeli, Walter E. and Mikus, Gerd}, title={Perpetrator characteristics of azole antifungal drugs on three oral factor Xa inhibitors administered as a microdosed cocktail}, year={2022}, pages={97-109}, language={eng}, issn={1179-1926}, volume={61}, number={1}, note={Online ver{\"o}ffentlicht am 17. Juli 2021 ; Gesehen am 04.01.2023}, journal={Clinical pharmacokinetics}, doi={10.1007/s40262-021-01051-9}, url={https://doi.org/10.1007/s40262-021-01051-9}, library={UB}, } @article{UBHD-69305455, author={Rohr, Brit Silja and Krohmer, Evelyn and Foerster, Kathrin and Burhenne, J{\"u}rgen and Schulz, Martin and Blank, Antje and Mikus, Gerd and Haefeli, Walter E.}, title={Time course of the interaction between oral short-term ritonavir therapy with three factor Xa inhibitors and the activity of CYP2D6, CYP2C19, and CYP3A4 in healthy volunteers}, year={2024}, pages={469-481}, language={eng}, issn={1179-1926}, volume={63}, number={4}, note={Gesehen am 18.02.2025}, journal={Clinical pharmacokinetics}, doi={10.1007/s40262-024-01350-x}, } @article{UBHD-69273600, author={Rose, Fabian and K{\"o}berle, Beate and Honnen, Sebastian Jakob and Bay, Cindy and Burhenne, J{\"u}rgen and Weiß, Johanna and Haefeli, Walter E. and Theile, Dirk}, title={RNA is a pro-apoptotic target of cisplatin in cancer cell lines and C. elegans}, year={2024}, pages={116450-1-116450-10}, language={eng}, issn={1950-6007}, volume={173}, number={Artikel-ID 116450}, note={Gesehen am 14.11.2024}, journal={Biomedicine & pharmacotherapy}, doi={10.1016/j.biopha.2024.116450}, } @article{UBHD-68915166, author={Rudofsky, Leonie and Burhenne, J{\"u}rgen and Weiß, Johanna and V{\"o}lker, Michael and Unger, Matthias and Mikus, Gerd and Haefeli, Walter E.}, title={Daily honey consumption does not change CYP3A activity in humans}, year={2011}, pages={1223-1232}, language={eng}, issn={1552-4604}, volume={51}, number={8}, note={Elektronische Reproduktion der Druckausgabe ; Gesehen am 05.05.2022}, journal={Journal of clinical pharmacology}, doi={10.1177/0091270010382022}, } @article{UBHD-68470476, author={Russo, Alexandra and Burhenne, J{\"u}rgen and Fresnais, Margaux}, title={Ceritinib-induced regression of an insulin-like growth factor-driven neuroepithelial brain tumor}, year={2019}, pages={19 S.}, language={eng}, issn={1422-0067 and 1661-6596}, volume={20(2019}, note={Gesehen am 23.12.2019}, journal={International journal of molecular sciences}, doi={10.3390/ijms20174267}, } @article{UBHD-68629785, author={Sadik, Ahmed and Somarribas Patterson, Luis F. and {\"O}zt{\"u}rk, Selcen and Mohapatra, Soumya R. and Panitz, Verena and Secker, Philipp F. and Holfelder, Pauline and Loth, Stefanie and Salem, Heba and Prentzell, Mirja Tamara and Berdel, Bianca and Iskar, Murat and Faessler, Erik and Reuter, Friederike and Kirst, Isabelle and Kalter, Verena and Foerster, Kathrin and J{\"a}ger, Evelyn and Guevara, Carina Ramallo and Sobeh, Mansour and Hielscher, Thomas and Poschet, Gernot and Reinhardt, Annekathrin and Hassel, Jessica C. and Zapatka, Marc and Hahn, Udo and Deimling, Andreas von and Hopf, Carsten and Schlichting, Rita and Escher, Beate I. and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Ishaque, Naveed and B{\"o}hme, Alexander and Sch{\"a}uble, Sascha and Thedieck, Kathrin and Trump, Saskia and Seiffert, Martina and Opitz, Christiane}, title={IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression}, year={2020}, pages={1252-1270.e34}, language={eng}, issn={1097-4172}, volume={182}, number={5}, note={Gesehen am 21.08.2020}, journal={Cell}, doi={10.1016/j.cell.2020.07.038}, } @article{UBHD-69122554, author={Sauter, Max and Blank, Antje and Stoll, Felicitas E. and Lutz, Natalie and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Intact plasma quantification of the large therapeutic lipopeptide bulevirtide}, year={2021}, pages={5645-5654}, language={eng}, issn={1618-2650}, volume={413}, number={22}, note={Gesehen am 18.09.2023}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-021-03384-7}, url={https://doi.org/10.1007/s00216-021-03384-7}, library={UB}, } @article{UBHD-68676462, author={Sauter, Max and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Uhl, Philipp}, title={An underestimated factor}, subtitle={the extent of cross-reactions modifying APIs in surface-modified liposomal preparations caused by comprised activated lipids}, year={2020}, language={eng}, issn={1420-3049}, volume={25(2020}, note={Gesehen am 04.01.2021}, journal={Molecules}, doi={10.3390/molecules25194436}, } @article{UBHD-68764757, author={Sauter, Max and Foerster, Kathrin and Benzel, Julia and Pfister, Stefan and Pajtler, Kristian Wilfried and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS}, year={2021}, pages={1-6}, language={eng}, issn={1873-376X}, volume={1176}, number={Artikel-ID 122781}, note={Gesehen am 29.07.2021}, journal={Journal of chromatography}, doi={10.1016/j.jchromb.2021.122781}, } @article{UBHD-68701539, author={Sauter, Max and Uhl, Philipp and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Application of triple quadrupole tandem mass spectrometry to the bioanalysis of collision-induced dissociation-resistant cyclic peptides}, subtitle={ultra-sensitive quantification of the somatostatin-analog pasireotide utilizing UHPLC-MS/MS}, year={2021}, language={eng}, issn={1873-264X}, volume={194(2021) Artikel-Nummer 113728}, number={7 Seiten}, note={Available online 5 November 2020 ; Gesehen am 19.02.2021}, journal={Journal of pharmaceutical and biomedical analysis}, doi={10.1016/j.jpba.2020.113728}, } @article{UBHD-68714353, author={Sauter, Max and Uhl, Philipp and Meid, Andreas and Mikus, Gerd and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={New insights into the pharmacokinetics of vancomycin after oral and intravenous administration}, subtitle={an investigation in beagle dogs}, year={2020}, pages={2090-2094}, language={eng}, issn={1520-6017}, volume={109}, number={6}, note={Gesehen am 19.03.2021}, journal={Journal of pharmaceutical sciences}, doi={10.1016/j.xphs.2020.03.012}, } @article{UBHD-68583765, author={Sauter, Max and Uhl, Philipp and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Post-extraction disulfide bond cleavage for MS/MS quantification of collision-induced dissociation-resistant cystine-cyclized peptides and its application to the ultra-sensitive UPLC-MS/MS bioanalysis of octreotide in plasma}, year={2020}, pages={42-49}, language={eng}, issn={1873-4324}, volume={1114}, note={Gesehen am 04.06.2020}, journal={Analytica chimica acta}, doi={10.1016/j.aca.2020.04.016}, } @article{UBHD-68445773, author={Sauter, Max and Uhl, Philipp and Majewsky, Marius and Fresnais, Margaux and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={An ultrasensitive UPLC-MS/MS assay for the quantification of the therapeutic peptide liraglutide in plasma to assess the oral and nasal bioavailability in beagle dogs}, year={2019}, pages={887-898}, language={eng}, issn={1757-6199}, volume={11}, number={9}, note={Gesehen am 25.10.2019}, journal={Bioanalysis}, doi={10.4155/bio-2018-0322}, } @book{UBHD-68587313, author={Sauter, Max and Uhl, Philipp and Majewsky, Marius and Fresnais, Margaux and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={An ultrasensitive UPLC–MS/MS assay for the quantification of the therapeutic peptide liraglutide in plasma to assess the oral and nasal bioavailability in beagle dogs}, edition={Zweitver{\"o}ffentlichung}, publisher={Future Science}, address={London}, year={2019}, pages={1 Online-Ressource (12 Seiten)}, language={eng}, note={In: Bioanalysis, 11 (2019), Nr. 9. pp. 887-898. ISSN 1757-6180 (Druck-Ausg.), 1757-6199 (Online-Ausg.)}, doi={10.11588/heidok.00028429}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-284291}, library={UB}, } @article{UBHD-68621310, author={Sauter, Max and Uhl, Philipp and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS}, year={2020}, pages={233-239}, language={eng}, issn={2214-0883}, volume={10}, number={3}, note={Gesehen am 28.07.2020}, journal={Journal of pharmaceutical analysis}, doi={10.1016/j.jpha.2020.02.008}, } @article{UBHD-68617280, author={Sauter, Max and Uhl, Philipp and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics}, year={2020}, pages={6 S.}, language={eng}, issn={1873-264X}, volume={186(2020) Artikel-Nummer 113276}, number={6 Seiten}, note={Gesehen am 15.07.2020}, journal={Journal of pharmaceutical and biomedical analysis}, doi={10.1016/j.jpba.2020.113276}, } @article{UBHD-68304288, author={Sch{\"a}fer, Julia and Welti, Lukas and Seckinger, Anja and Burhenne, J{\"u}rgen and Theile, Dirk and Weiß, Johanna}, title={Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient}, year={2017}, pages={71-79}, language={eng}, issn={1432-0843}, volume={80}, number={1}, note={Published online: 12 May 2017 ; Gesehen am 12.09.2018}, journal={Cancer chemotherapy and pharmacology}, doi={10.1007/s00280-017-3335-4}, } @article{UBHD-68374115, author={Sch{\"a}fer, Julia and Burhenne, J{\"u}rgen and Weiß, Johanna and Theile, Dirk}, title={Elucidating the beneficial effects of melphalan, adriamycin, and corticoids in combination with bortezomib against multiple myeloma in vitro}, year={2019}, pages={461-466}, language={eng}, issn={1432-1912}, volume={392}, number={4}, note={Published online: 15 December 2018 ; Gesehen am 29.03.2019}, journal={Naunyn-Schmiedeberg's archives of pharmacology}, doi={10.1007/s00210-018-01602-1}, } @article{UBHD-67938668, author={Schmitt, Thomas and Goldschmidt, Hartmut and Neben, Kai and Freiberger, Anja and H{\"u}sing, Johannes and Gronkowski, Martina and Thalheimer, Markus and Pelzl, Le Hang and Mikus, Gerd and Burhenne, J{\"u}rgen and Ho, Anthony Dick and Egerer, Gerlinde}, title={Aprepitant, Granisetron, and Dexamethasone for prevention of chemotherapy-induced nausea and vomiting after high-dose Melphalan in autologous transplantation for multiple myeloma}, subtitle={results of a randomized, placebo-controlled phase III trial}, year={2014}, pages={3413-3420}, language={eng}, issn={1527-7755}, volume={32}, number={30}, note={Gesehen am 09.02.2016}, journal={Journal of clinical oncology}, doi={10.1200/JCO.2013.55.0095}, } @article{UBHD-68069056, author={Schmitt, Thomas and Kasper, Bernd and H{\"u}sing, Johannes and Hajda, Jacek and Ottawa, Gregor and Mechtersheimer, Gunhild and Mikus, Gerd and Burhenne, J{\"u}rgen and Lehmann, Lorenz and Heilig, Christoph E. and Ho, Anthony Dick and Egerer, Gerlinde}, title={Vorinostat in refractory soft tissue sarcomas}, subtitle={results of a multi-centre phase II trial of the German Soft Tissue Sarcoma and Bone Tumour Working Group (AIO)}, year={2016}, pages={74-82}, language={eng}, issn={1879-0852}, volume={64}, note={Gesehen am 04.01.2017}, journal={European journal of cancer}, doi={10.1016/j.ejca.2016.05.018}, } @article{UBHD-69112844, author={Stoll, Felicitas E. and Blank, Antje and Mikus, Gerd and Czock, David and Foerster, Kathrin and Hermann, Simon and G{\"u}m{\"u}s, Katja S. and Muhareb, Amin and Hummler, Simone and Sauter, Max and Weiß, Johanna and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Effect of pantoprazole on the absorption of Hydroxychloroquinea A randomized drug-drug interaction trial in healthy adults}, year={2022}, pages={285-290}, language={eng}, issn={2160-7648}, volume={11}, number={2}, note={First published: 15 July 2021 ; Gesehen am 15.08.2023}, journal={Clinical pharmacology in drug development}, doi={10.1002/cpdd.999}, url={https://doi.org/10.1002/cpdd.999}, library={UB}, } @article{UBHD-69188254, author={Stoll, Felicitas E. and Blank, Antje and Mikus, Gerd and Czock, David and Weiß, Johanna and Meyer-T{\"o}nnies, Marleen J. and G{\"u}m{\"u}s, Katja S. and Tzvetkov, Mladen Vassilev and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Evaluation of hydroxychloroquine as a perpetrator on cytochrome P450 (CYP) 3A and CYP2D6 activity with microdosed probe drugs in healthy volunteers}, year={2024}, pages={101-109}, language={eng}, issn={2107-0180}, volume={49}, number={1}, note={Gesehen am 05.03.2024 ; Onlineversion: 20 Dezember 2023, Artikelversion: Januar 2024}, journal={European journal of drug metabolism and pharmacokinetics}, doi={10.1007/s13318-023-00872-2}, } @article{UBHD-68620399, author={Stoll, Felicitas E. and Blank, Antje and Mikus, Gerd and Czock, David and Foerster, Kathrin and Hermann, Simon and G{\"u}m{\"u}s, Katja S. and Muhareb, Amin and Hummler, Simone and Weiß, Johanna and Burhenne, J{\"u}rgen and Haefeli, Walter E.}, title={Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19)}, subtitle={A structured summary of a study protocol for a randomised controlled trial}, year={2020}, pages={1-2}, language={eng}, issn={1468-6694 and 1745-6215}, volume={21}, number={Artikel-ID 584}, note={Gesehen am 23.07.2020}, journal={Trials}, doi={10.1186/s13063-020-04476-y}, } @article{UBHD-69043906, author={Stoll, Felicitas E. and Seidel-Gl{\"a}tzer, Andrea and Burghaus, Ina and G{\"o}ring, Oliver and Sauter, Max and Rose, Peter and Daniel, Volker and Haag, Mathias and Schwab, Matthias and Riffel, Johannes and André, Florian and Taylor, Lenka A. and Weiß, Johanna and Burhenne, J{\"u}rgen and Cleeves, Volker and Haefeli, Walter E. and Blank, Antje}, title={Metabolic effect of blocking sodium-taurocholate co-transporting polypeptide in hypercholesterolemic humans with a twelve-week course of bulevirtide}, subtitle={n exploratory phase I clinical trial}, year={2022}, pages={1-16}, language={eng}, issn={1422-0067 and 1661-6596}, volume={23}, note={Gesehen am 21.02.2023}, journal={International journal of molecular sciences}, doi={10.3390/ijms232415924}, } @article{UBHD-68892665, author={Stoll, Felicitas E. and Burhenne, J{\"u}rgen and Lausecker, Berthold and Weiß, Johanna and Thomsen, Torben and Haefeli, Walter E. and Mikus, Gerd}, title={Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity}, year={2013}, pages={1199-1204}, language={eng}, issn={1552-4604}, volume={53}, number={11}, note={Gesehen am 08.03.2022}, journal={Journal of clinical pharmacology}, doi={10.1002/jcph.161}, } @article{UBHD-68738859, author={Streit, Michael and G{\"o}ggelmann, Christoph and Dehnert, Christoph and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Menold, Elmar and Mikus, Gerd and B{\"a}rtsch, Peter and Haefeli, Walter E.}, title={Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m)}, year={2005}, pages={39-46}, language={eng}, issn={1432-1041}, volume={61}, number={1}, note={Gesehen am 18.05.2021 ; Im Titel ist "450" tiefgestellt}, journal={European journal of clinical pharmacology}, doi={10.1007/s00228-004-0886-1}, } @article{UBHD-68263299, author={Suzuki, Yosuke and Witt, Lukas and Mier, Walter and Mikus, Gerd and Markert, Christoph and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Ultra-sensitive and selective quantification of endothelin-1 in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry}, year={2017}, pages={84-90}, language={eng}, issn={1873-264X}, volume={142}, note={Available online 29 April 2017 ; Gesehen am 20.06.2018}, journal={Journal of pharmaceutical and biomedical analysis}, doi={10.1016/j.jpba.2017.04.038}, } @article{UBHD-68740517, author={Tayrouz Haffar, Yorki Antoine and Ding, Reinhard and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Weiß, Johanna and Hoppe-Tichy, Torsten and Haefeli, Walter E. and Mikus, Gerd}, title={Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40}, year={2003}, pages={397-405}, language={eng}, issn={1532-6535}, volume={73}, number={5}, note={Gesehen am 25.05.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1016/S0009-9236(03)00059-6}, } @article{UBHD-68741137, author={Tayrouz Haffar, Yorki Antoine and Ganßmann, Beate and Ding, Reinhard and Klingmann, Andrea and Aderjan, Rolf and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Mikus, Gerd}, title={Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement}, year={2001}, pages={405-414}, language={eng}, issn={1532-6535}, volume={70}, number={5}, note={Gesehen am 26.05.2021}, journal={Clinical pharmacology & therapeutics}, doi={10.1016/S0009-9236(01)35864-2}, } @article{UBHD-68240966, author={Theile, Dirk and Detering, Jan-Christoph and Herold-Mende, Christel and Dyckhoff, Gerhard and Haefeli, Walter E. and Weiß, Johanna and Burhenne, J{\"u}rgen}, title={Cellular pharmacokinetic/pharmacodynamic relationship of platinum cytostatics in head and neck squamous cell carcinoma evaluated by liquid chromatography coupled to tandem mass spectrometry}, year={2012}, pages={51-58}, language={eng}, issn={1521-0103}, volume={341}, number={1}, note={Gesehen am 09.04.2018}, journal={The journal of pharmacology and experimental therapeutics}, doi={10.1124/jpet.111.189621}, } @article{UBHD-68579599, author={Tilburg, Cornelis M. van and Milde, Till and Witt, Ruth and Ecker, Jonas and Hielscher, Thomas and Seitz, Angelika and Schenk, Jens-Peter and Buhl, Juliane and Riehl, Dennis and Fr{\"u}hwald, Michael and Pekrun, Arnulf and R{\"o}ssig, Claudia and Wieland, Regina Paula Franziska and Flotho, Christian and Kordes, Uwe and Gruhn, Bernd and Simon, Thorsten and Linderkamp, Christin and Sahm, Felix and Taylor, Lenka A. and Freitag, Angelika and Burhenne, J{\"u}rgen and Foerster, Kathrin and Meid, Andreas and Pfister, Stefan and Karapanagiotou-Schenkel, Irini and Witt, Olaf}, title={Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia}, year={2019}, pages={15 S.}, language={eng}, issn={1868-7083}, volume={11(2019) Artikel-Nummer 188}, number={15 Seiten}, note={Gesehen am 20.05.2020}, journal={Clinical epigenetics}, doi={10.1186/s13148-019-0775-1}, } @book{UBHD-68587316, author={Vay, Manuela and Sauter, Max and Mikus, Gerd and Burhenne, J{\"u}rgen}, title={Quantification of microdosed oral yohimbine and its major metabolite in human plasma in the picogram range}, edition={Zweitver{\"o}ffentlichung}, publisher={Future Science}, address={London}, year={2019}, pages={1 Online-Ressource (12 Seiten)}, language={eng}, note={In: Bioanalysis, 11 (2019), Nr. 16. pp. 1459-1467. ISSN 1757-6180 (Druck-Ausg.), 1757-6199 (Online-Ausg.)}, doi={10.11588/heidok.00028431}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-284311}, library={UB}, } @article{UBHD-68473974, author={Vay, Manuela and Skopp, Gisela and Mikus, Gerd and Burhenne, J{\"u}rgen}, title={Simultaneous quantification of the CYP2D6 substrate yohimbine, its metabolite 11-OH-yohimbine, and the CYP2D6 inhibitor paroxetine in human plasma}, year={2019}, pages={5976-5983}, language={eng}, issn={1759-9679}, volume={11}, number={47}, note={Gesehen am 10.01.2019}, journal={Analytical methods}, doi={10.1039/C9AY01715A}, } @article{UBHD-68814108, author={Wass, Maxi and G{\"o}llner, Stefanie and Besenbeck, Birgit and Schlenk, Richard Friedrich and Mundmann, Petra and G{\"o}thert, Joachim Rudolf and Noppeney, Richard and Schliemann, Christoph and Mikesch, Jan-Henrik and Lenz, Georg and Dugas, Martin and Wermke, Martin and R{\"o}llig, Christoph and Bornh{\"a}user, Martin and Serve, Hubert and Platzbecker, Uwe and Foerster, Kathrin and Burhenne, J{\"u}rgen and Haefeli, Walter E. and M{\"u}ller, Lutz P. and Binder, Mascha and Pabst, Caroline and M{\"u}ller-Tidow, Carsten}, title={A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy}, year={2021}, pages={701-711}, language={eng}, issn={1476-5551}, volume={35}, number={3}, note={Online ver{\"o}ffentlicht: 19 June 2020}, journal={Leukemia}, doi={10.1038/s41375-020-0892-z}, } @article{UBHD-68384862, author={Weinheimer, Manuel and Fricker, Gert and Burhenne, J{\"u}rgen}, title={The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers}, subtitle={an in vitro and in vivo comparison}, year={2017}, pages={13-22}, language={eng}, issn={1879-0720}, volume={108}, note={Available online 30 August 2016 ; Gesehen am 06.05.2019}, journal={European journal of pharmaceutical sciences}, doi={10.1016/j.ejps.2016.08.055}, } @article{UBHD-68942652, author={Weiß, Johanna and Foerster, Kathrin and Weber, Maria and Burhenne, J{\"u}rgen and Mikus, Gerd and Lehr, Thorsten and Haefeli, Walter E.}, title={Does the circulating ketoconazole metabolite N-deacetyl ketoconazole contribute to the drug-drug interaction potential of the parent compound?}, year={2022}, pages={1-8}, language={eng}, issn={1879-0720}, volume={169}, number={Artikel-ID 106076}, note={Available online 29 November 2021 ; Gesehen am 15.07.2022}, journal={European journal of pharmaceutical sciences}, doi={10.1016/j.ejps.2021.106076}, } @article{UBHD-68388363, author={Weiß, Johanna and Theile, Dirk and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Haefeli, Walter E.}, title={Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells}, year={2013}, pages={265-273}, language={eng}, issn={1873-2968}, volume={85}, number={2}, note={Available online 5 December 2012 ; Gesehen am 09.05.2019}, journal={Biochemical pharmacology}, doi={10.1016/j.bcp.2012.11.020}, } @article{UBHD-68741072, author={Weiß, Johanna and Burhenne, J{\"u}rgen and Riedel, Klaus-Dieter and Haefeli, Walter E.}, title={Poor solubility limiting significance of in-vitro studies with HIV protease inhibitors}, year={2002}, pages={674-676}, language={eng}, issn={1473-5571}, volume={16}, number={4}, note={Gesehen am 26.05.2021}, journal={AIDS }, doi={10.1097/00002030-200203080-00024}, } @article{UBHD-68069513, author={Witt, Lukas and Hohmann, Nicolas and Mikus, Gerd and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry after chlorzoxazone microdosing}, year={2016}, pages={207-213}, language={eng}, issn={1873-376X}, volume={1027}, note={Gesehen am 05.01.2017}, journal={Journal of chromatography}, doi={10.1016/j.jchromb.2016.05.049}, } @article{UBHD-68329808, author={Wolfert, Christina Lisa and Meid, Andreas and Burhenne, J{\"u}rgen and Blank, Antje and Mikus, Gerd}, title={Management von chronischem Schmerz mit retardiertem Tilidin}, subtitle={Lebensqualit{\"a}t und Bedeutung der Komedikation f{\"u}r den Tilidinmetabolismus}, year={2017}, pages={516-523}, language={ger}, issn={1432-2129}, volume={31}, number={5}, note={Gesehen am 19.11.2018}, journal={Der Schmerz}, doi={10.1007/s00482-017-0228-8}, } @article{UBHD-68282785, author={Yimer, Getnet and Haefeli, Walter E. and Burhenne, J{\"u}rgen}, title={High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia}, subtitle={a prospective cohort study}, year={2012}, pages={499-506}, language={eng}, issn={1473-1150}, volume={12}, number={6}, note={Published online 23 August 2011 ; Gesehen am 05.07.2018}, journal={The pharmacogenomics journal}, doi={10.1038/tpj.2011.34}, } @article{UBHD-68995858, author={Yimer, Getnet and Ueda, Nobuhisa and Habtewold, Abiy and Amogne, Wondwossen and Suda, Akira and Riedel, Klaus-Dieter and Burhenne, J{\"u}rgen and Aderaye, Getachew and Lindquist, Lars and Makonnen, Eyasu and Aklillu, Eleni}, title={Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients}, year={2011}, pages={1-9}, language={eng}, issn={1932-6203}, volume={6}, note={Gesehen am 12.12.2022}, journal={PLOS ONE}, doi={10.1371/journal.pone.0027810}, } @article{UBHD-68995870, author={Yin, Jun and Kukucka, Marian and Hoffmann, Julia and Sterner-Kock, Anja and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Kuppe, Hermann and K{\"u}bler, Wolfgang Michael}, title={Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure}, year={2011}, pages={198-206}, language={eng}, issn={1941-3297}, volume={4}, number={2}, note={Gesehen am 12.12.2022}, journal={Circulation}, doi={10.1161/CIRCHEARTFAILURE.110.957050}, } @article{UBHD-68763731, author={Zembruski, Nadine Cécile Luise and Theile, Dirk and Burhenne, J{\"u}rgen and Haefeli, Walter E. and Weiß, Johanna}, title={Liposomal sphingomyelin influences the cellular lipid profile of human lymphoblastic leukemia cells without effect on P-glycoprotein activity}, year={2013}, pages={1020-1034}, language={eng}, issn={1543-8392}, volume={10}, number={3}, note={Gesehen am 27.07.2021}, journal={Molecular pharmaceutics}, doi={10.1021/mp300485j}, } @article{UBHD-69124550, author={Zhou, Xu and An, Jingyu and Kurilov, Roman and Brors, Benedikt and Hu, Kai and Peccerella, Teresa and R{\"o}ssler, Stephanie and Pf{\"u}tze, Katrin and Schulz, Angela and Wolf, Stephan and Hohmann, Nicolas and Theile, Dirk and Sauter, Max and Burhenne, J{\"u}rgen and Ei, Shigenori and Heger, Ulrike and Strobel, Oliver and Barry, Simon T. and Springfeld, Christoph and Tjaden, Christin and Bergmann, Frank and B{\"u}chler, Markus W. and Hackert, Thilo and Fortunato, Franco and Neoptolemos, John P. and Bailey, Peter}, title={Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC}, year={2023}, pages={1362-1381}, language={eng}, issn={2662-1347}, volume={4}, number={9}, note={Gesehen am 26.09.2023}, journal={Nature cancer}, doi={10.1038/s43018-023-00628-6}, } @article{UBHD-69079897, author={Zhu, Vanessa and Burhenne, J{\"u}rgen and Weiß, Johanna and Haag, Mathias and Hofmann, Ute and Schwab, Matthias and Urban, Stephan and Mikus, Gerd and Czock, David and Haefeli, Walter E. and Blank, Antje}, title={Evaluation of the drug-drug interaction potential of the novel hepatitis B and D virus entry inhibitor bulevirtide at OATP1B in healthy volunteers}, year={2023}, pages={1-13}, language={eng}, issn={1663-9812}, volume={14(2023) vom: Apr.}, number={Artikel-ID 1128547}, note={Gesehen am 26.05.2023}, journal={Frontiers in pharmacology}, doi={10.3389/fphar.2023.1128547}, url={https://doi.org/10.3389/fphar.2023.1128547}, library={UB}, }