@article{UBHD-68590129, author={Bastos Lima, Allan and Behnam, Mira A. M. and El Sherif, Yasmin and Nitsche, Christoph and Vechi, Sergio and Klein, Christian D.}, title={Dual inhibitors of the dengue and West Nile virus NS2B-NS3 proteases}, subtitle={synthesis, biological evaluation and docking studies of novel peptide-hybrids}, year={2015}, pages={5748-5755}, language={eng}, issn={1464-3391}, volume={23}, number={17}, note={Gesehen am 23.06.2020}, journal={Bioorganic & medicinal chemistry}, doi={10.1016/j.bmc.2015.07.012}, } @article{UBHD-69162580, author={Behnam, Mira A. M. and Basché, Thomas and Klein, Christian D.}, title={2,2′-Bithiophene as sensor tag for ligand-protein binding assays based on F{\"o}rster resonance energy transfer}, year={2023}, pages={1-7}, language={eng}, issn={1096-0309}, volume={682}, number={Artikel-ID 115335}, note={Gesehen am 17.01.2024}, journal={Analytical biochemistry}, doi={10.1016/j.ab.2023.115335}, } @article{UBHD-69314986, author={Behnam, Mira A. M. and Klein, Christian D.}, title={Alternate recognition by dengue protease}, subtitle={proteolytic and binding assays provide functional evidence beyond an induced-fit}, year={2024}, pages={15-27}, language={eng}, volume={227(2024) vom: Dez.}, note={Online verf{\"u}gbar: 11. Juni 2024, Artikelversion: 3. Dezember 2024 ; Gesehen am 05.03.2025}, journal={Biochimie}, doi={10.1016/j.biochi.2024.06.002}, } @article{UBHD-68647886, author={Behnam, Mira A. M. and Klein, Christian D.}, title={Conformational selection in the flaviviral NS2B-NS3 protease}, year={2020}, pages={117-125}, language={eng}, volume={174}, note={Gesehen am 13.10.2020}, journal={Biochimie}, doi={10.1016/j.biochi.2020.04.014}, } @article{UBHD-68634789, author={Behnam, Mira A. M. and Nitsche, Christoph and Vechi, Sergio and Klein, Christian D.}, title={C-Terminal residue optimization and fragment merging}, subtitle={discovery of a potent peptide-hybrid inhibitor of Dengue protease}, year={2014}, pages={1037-1042}, language={eng}, issn={1948-5875}, volume={5}, number={9}, note={Gesehen am 04.09.2020}, journal={ACS medicinal chemistry letters}, doi={10.1021/ml500245v}, } @article{UBHD-68623866, author={Behnam, Mira A. M. and Graf, Dominik Korbinian and Bartenschlager, Ralf and Zlotos, Darius P. and Klein, Christian D.}, title={Discovery of nanomolar dengue and West Nile virus protease inhibitors containing a 4-benzyloxyphenylglycine residue}, year={2015}, pages={9354-9370}, language={eng}, issn={1520-4804}, volume={58}, number={23}, note={Gesehen am 04.08.2020}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.5b01441}, } @article{UBHD-68802718, author={Behnam, Mira A. M. and Klein, Christian D.}, title={Inhibitor potency and assay conditions}, subtitle={a case study on SARS-CoV-2 main protease}, year={2021}, pages={1-2}, language={eng}, issn={1091-6490}, volume={118}, note={Gesehen am 17.11.2021}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.2106095118}, } @article{UBHD-68573228, author={Behnam, Mira A. M. and Nitsche, Christoph and Boldescu, Veaceslav and Klein, Christian D.}, title={The medicinal chemistry of dengue virus}, year={2016}, pages={5622-5649}, language={eng}, issn={1520-4804}, volume={59}, number={12}, note={Gesehen am 05.05.2020}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.5b01653}, } @article{UBHD-68878262, author={Behnam, Mira A. M. and Klein, Christian D.}, title={On track to tackle dengue}, subtitle={History and future of NS4B ligands}, year={2021}, pages={1735-1737}, language={eng}, issn={1934-6069}, volume={29}, number={12}, note={Gesehen am 15.02.2022}, journal={Cell host and microbe}, doi={10.1016/j.chom.2021.11.010}, } @book{UBHD-68102798, author={Behnam, Mira A. M.}, organization={Universit{\"a}t Heidelberg}, title={Peptidic and peptidomimetic inhibitors of dengue protease}, address={Heidelberg}, year={2016}, pages={XIII, 168 Seiten}, language={eng}, school={Dissertation, Ruperto-Carola University of Heidelberg, 2016}, library={UB [Signatur: 2017 U 210]}, } @article{UBHD-68718680, author={Behnam, Mira A. M.}, title={Protein structural heterogeneity}, subtitle={a hypothesis for the basis of proteolytic recognition by the main protease of SARS-CoV and SARS-CoV-2}, year={2021}, pages={177-184}, language={eng}, volume={182}, note={Gesehen am 12.05.2021}, journal={Biochimie}, doi={10.1016/j.biochi.2021.01.010}, } @article{UBHD-68573230, author={Behnam, Mira A. M. and Sundermann, Tom R. and Klein, Christian D.}, title={Solid phase synthesis of C-terminal boronic acid peptides}, year={2016}, pages={2016-2019}, language={eng}, issn={1523-7052}, volume={18}, number={9}, note={Gesehen am 05.05.2020}, journal={Organic letters}, doi={10.1021/acs.orglett.6b00625}, } @article{UBHD-68299964, author={Boldescu, Veaceslav and Behnam, Mira A. M. and Klein, Christian D.}, title={Broad-spectrum agents for flaviviral infections}, subtitle={dengue, Zika and beyond}, year={2017}, pages={565-586}, language={eng}, issn={1474-1784}, volume={16}, number={8}, note={Gesehen am 29.08.2018}, journal={Nature reviews}, doi={10.1038/nrd.2017.33}, } @article{UBHD-68749325, author={K{\"u}hl, Nikos and Leuthold, Mila and Behnam, Mira A. M. and Klein, Christian D.}, title={Beyond basicity}, subtitle={discovery of nonbasic DENV-2 protease inhibitors with potent activity in cell culture}, year={2021}, pages={4567-4587}, language={eng}, issn={1520-4804}, volume={64}, number={8}, note={Gesehen am 16.06.2021}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.0c02042}, } @article{UBHD-68640015, author={K{\"u}hl, Nikos and Graf, Dominik Korbinian and Bock, Josephine and Behnam, Mira A. M. and Leuthold, Mila and Klein, Christian D.}, title={A new class of Dengue and west Nile virus protease inhibitors with submicromolar activity in reporter gene DENV-2 protease and viral replication assays}, year={2020}, pages={8179-8197}, language={eng}, issn={1520-4804}, volume={63}, number={15}, note={Gesehen am 24.09.2020}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.0c00413}, } @article{UBHD-68305750, author={Liang, Chen and Behnam, Mira A. M. and Sundermann, Tom R. and Klein, Christian D.}, title={Phenylglycine racemization in Fmoc-based solid-phase peptide synthesis}, subtitle={stereochemical stability is achieved by choice of reaction conditions}, year={2017}, pages={2325-2329}, language={eng}, issn={1873-3581}, volume={58}, number={24}, note={Gesehen am 18.09.2018}, journal={Tetrahedron letters}, doi={10.1016/j.tetlet.2017.04.047}, } @article{UBHD-68259868, author={Nitsche, Christoph and Behnam, Mira A. M. and Steuer, Christian and Klein, Christian D.}, title={Retro peptide-hybrids as selective inhibitors of the Dengue virus NS2B-NS3 protease}, year={2012}, pages={72-79}, language={eng}, issn={1872-9096}, volume={94}, number={1}, note={Gesehen am 11.06.2018}, journal={Antiviral research}, doi={10.1016/j.antiviral.2012.02.008}, } @article{UBHD-67700748, author={Nitsche, Christoph and Schreier, Verena Natalie and Behnam, Mira A. M. and Kumar, Anil and Bartenschlager, Ralf and Klein, Christian D.}, title={Thiazolidinone-peptide hybrids as dengue virus protease inhibitors with antiviral activity in cell culture}, year={2013}, pages={8389-8403}, language={eng}, issn={1520-4804}, volume={56}, number={21}, note={Gesehen am 07.11.2014}, journal={Journal of medicinal chemistry}, doi={10.1021/jm400828u}, }