@article{UBHD-68788393,
  author={Baumann, Daniel and Drebant, Jennifer and H{\"a}gele, Tanja and Burger, Luisa and Serger, Clara and Lauenstein, Claudia and Dudys, Przemyslaw and Erdmann, Gerrit and Offringa, Rienk},
  title={p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition},
  year={2021},
  pages={1-9},
  language={eng},
  issn={2051-1426},
  volume={9},
  note={Gesehen am 11.10.2021},
  journal={Journal for ImmunoTherapy of Cancer},
  doi={10.1136/jitc-2020-002319},
}
@article{UBHD-68614724,
  author={Baumann, Daniel and H{\"a}gele, Tanja and Mochayedi, Julian and Drebant, Jennifer and Vent, Caroline and Blobner, Sven and Noll, Julia Han and Nickel, Irena and Schumacher, Corinna and Boos, Sophie Luise and Daniel, Aline Sophie and Wendler, Susann and Volkmar, Michael and Strobel, Oliver and Offringa, Rienk},
  title={Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy},
  year={2020},
  pages={18 S.},
  language={eng},
  issn={2041-1723},
  volume={11(2020) Artikel-Nummer 2176},
  number={18 Seiten},
  note={Gesehen am 08.07.2020},
  journal={Nature Communications},
  doi={10.1038/s41467-020-15979-2},
}
@article{UBHD-69354453,
  author={Baumann, Daniel and Offringa, Rienk},
  title={Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy},
  year={2020},
  pages={248-251},
  language={eng},
  issn={2523-0204},
  volume={4},
  number={10 vom: Okt.},
  note={Gesehen am 06.06.2025},
  journal={Cell stress},
  doi={10.15698/cst2020.10.233},
}
@article{UBHD-68239787,
  author={Cabo, Mariona and Offringa, Rienk},
  title={Trial Watch},
  subtitle={Immunostimulatory monoclonal antibodies for oncological indications},
  year={2017},
  language={eng},
  issn={2162-402X},
  volume={6(2017},
  note={Gesehen am 05.04.2018},
  journal={OncoImmunology},
  doi={10.1080/2162402X.2017.1371896},
}
@article{UBHD-68732670,
  author={Gengenbacher, Nicolas and Singhal, Mahak and Mogler, Carolin and Hai, Ling and Milde, Laura and Abdul Pari, Ashik Ahmed and Besemfelder, Eva and Fricke, Claudine and Baumann, Daniel and Gehrs, Stephanie and Utikal, Jochen and Felcht, Moritz and Hu, Junhao and Schlesner, Matthias and Offringa, Rienk and Chintharlapalli, Sudhakar R. and Augustin, Hellmut},
  title={Timed Ang2-targeted therapy identifies the Angiopoietin-tie pathway as key regulator of fatal lymphogenous metastasis},
  year={2021},
  pages={424-445},
  language={eng},
  issn={2159-8290},
  volume={11},
  number={2},
  note={Gesehen am 03.05.2021 ; Published online first October 26, 2020},
  journal={Cancer discovery},
  doi={10.1158/2159-8290.CD-20-0122},
}
@article{UBHD-68390000,
  author={Grees, Mareike and Baumann, Daniel and Eichm{\"u}ller, Stefan B. and Offringa, Rienk and Utikal, Jochen and Umansky, Viktor},
  title={Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models},
  year={2018},
  pages={1-14},
  language={eng},
  issn={2162-402X},
  volume={7},
  note={Gesehen am 15.05.2019},
  journal={OncoImmunology},
  doi={10.1080/2162402X.2018.1445457},
}
@book{UBHD-68493947,
  author={Hackert, Thilo and Strobel, Oliver and Offringa, Rienk and Springfeld, Christoph},
  organization={Universit{\"a}t Heidelberg},
  title={Vorhabenbezeichnung: Verbundvorhaben: eMED PANC-STRAT: Ein integrativer Ansatz f{\"u}r eine personalisierte Behandlung des Pankreas-Karzinoms - Projekte Universit{\"a}tsklinik Heidelberg},
  subtitle={Abschlussbericht Universit{\"a}t Heidelberg : Berichtszeitraum: 01.11.2016-31.10.2018},
  publisher={Ruprecht-Karls-Universit{\"a}t Heidelberg},
  address={[Heidelberg]},
  year={2018},
  pages={17 Bl{\"a}tter, 1 ungez{\"a}hltes Blatt},
  language={ger},
  note={F{\"o}rderkennzeichen BMBF 01ZX1605C ; Verbundnummer 01147730 ; Autoren dem Berichtsblatt entnommen ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden},
  keywords={Bauchspeicheldr{\"u}senkrebs / Biomarker / Genanalyse / Individualisierte Medizin / Systemmedizin},
}
@book{UBHD-68493948,
  author={Hackert, Thilo and Strobel, Oliver and Offringa, Rienk and Springfeld, Christoph},
  organization={Universit{\"a}t Heidelberg},
  title={Vorhabenbezeichnung: Verbundvorhaben: eMED PANC-STRAT: Ein integrativer Ansatz f{\"u}r eine personalisierte Behandlung des Pankreas-Karzinoms - Projekte Universit{\"a}tsklinik Heidelberg},
  subtitle={Abschlussbericht Universit{\"a}t Heidelberg : Berichtszeitraum: 01.11.2016-31.10.2018},
  publisher={Ruprecht-Karls-Universit{\"a}t Heidelberg},
  address={[Heidelberg]},
  year={2018},
  pages={1 Online-Ressource (18 Seiten, 591,90 KB)},
  language={ger},
  note={F{\"o}rderkennzeichen BMBF 01ZX1605C ; Verbundnummer 01147730 ; Autoren dem Berichtsblatt entnommen ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden},
  doi={10.2314/KXP:1684165687},
  keywords={Bauchspeicheldr{\"u}senkrebs / Biomarker / Genanalyse / Individualisierte Medizin / Systemmedizin},
}
@article{UBHD-68734197,
  author={Hartmann, Laura and Schr{\"o}ter, Philipp and Osen, Wolfram and Baumann, Daniel and Offringa, Rienk and Moustafa, Mahmoud and Will, Rainer D. and Debus, J{\"u}rgen and Brons, Stephan and Rieken, Stefan and Eichm{\"u}ller, Stefan B.},
  title={Photon versus carbon ion irradiation},
  subtitle={immunomodulatory effects exerted on murine tumor cell lines},
  year={2020},
  pages={1-13},
  language={eng},
  issn={2045-2322},
  volume={10},
  number={Artikel-ID 21517},
  note={Gesehen am 05.05.2021},
  journal={Scientific reports},
  doi={10.1038/s41598-020-78577-8},
}
@article{UBHD-68629268,
  author={Hartmann, Natalie and Giese, Nathalia and Giese, Thomas and Poschke, Isabel and Offringa, Rienk and Ryschich, Eduard},
  title={Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer},
  year={2014},
  pages={3422-3433},
  language={eng},
  issn={1557-3265},
  volume={20},
  number={13},
  note={Gesehen am 20.08.2020},
  journal={Clinical cancer research},
  doi={10.1158/1078-0432.CCR-13-2972},
}
@article{UBHD-68193393,
  author={Khandelwal, Nisit and Breinig, Marco and Poschke, Isabel and Offringa, Rienk},
  title={A high‐throughput RNAi screen for detection of immune‐checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes},
  year={2015},
  pages={450-463},
  language={eng},
  issn={1757-4684},
  volume={7},
  number={4},
  note={Gesehen am 22.11.2017},
  journal={EMBO molecular medicine},
  doi={10.15252/emmm.201404414},
}
@article{UBHD-69190132,
  author={Kober, Christina and Roewe, Julian and Schmees, Norbert and Roese, Lars and Roehn, Ulrike and Bader, Benjamin and Stoeckigt, Detlef and Prinz, Florian and Gorjánácz, Mátyás and Roider, Helge Gottfried and Olesch, Catherine and Leder, Gabriele and Irlbacher, Horst and Lesche, Ralf and Lefranc, Julien and Oezcan-Wahlbrink, Mine and Batra, Ankita Sati and Elmadany, Nirmeen and Carretero, Rafael and Sahm, Katharina and Oezen, Iris and Cichon, Frederik and Baumann, Daniel and Sadik, Ahmed and Opitz, Christiane A. and Weinmann, Hilmar and Hartung, Ingo V. and Kreft, Bertolt and Offringa, Rienk and Platten, Michael and Gutcher, Ilona},
  title={Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964},
  subtitle={a selective small molecule inhibitor for cancer immunotherapy},
  year={2023},
  pages={1-13},
  language={eng},
  issn={2051-1426},
  volume={11},
  note={Gesehen am 11.03.2024},
  journal={Journal for ImmunoTherapy of Cancer},
  doi={10.1136/jitc-2023-007495},
}
@article{UBHD-69192731,
  author={Meng, Zibo and Rodriguez Ehrenfried, Aaron and Tan, Chin Leng and Steffens, Laura K. and Kehm, Hannes and Zens, Stefan and Lauenstein, Claudia and Paul, Alina and Schwab, Marius and F{\"o}rster, Jonas and Salek, Mogjiborahman and Riemer, Angelika and Wu, Heshui and Eckert, Christoph and Leonhardt, Carl-Stephan and Strobel, Oliver and Volkmar, Michael and Poschke, Isabel and Offringa, Rienk},
  title={Transcriptome-based identification of tumor-reactive and bystander CD8+ T cell receptor clonotypes in human pancreatic cancer},
  year={2023},
  pages={1-18},
  language={eng},
  issn={1946-6242},
  volume={15},
  note={Im Text ist "+" hochgestellt ; Gesehen am 18.03.2024},
  journal={Science translational medicine},
  doi={10.1126/scitranslmed.adh9562},
}
@article{UBHD-68624312,
  author={Meng, Zibo and Yuan, Qingchen and Zhao, Jingyuan and Wang, Bo and Li, Shoukang and Offringa, Rienk and Jin, Xin and Wu, Heshui},
  title={The m6A-related mRNA signature predicts the prognosis of pancreatic cancer patients},
  year={2020},
  pages={460-470},
  language={eng},
  issn={2372-7705},
  volume={17},
  note={Im Titel ist die Ziffer 6 hochgestellt ; Gesehen am 05.08.2020},
  journal={Molecular therapy},
  doi={10.1016/j.omto.2020.04.011},
}
@article{UBHD-69318593,
  author={Mowat, Jeffrey and Carretero, Rafael and Leder, Gabriele and Aiguabella Font, Nuria and Neuhaus, Roland and Berndt, Sandra and G{\"u}nther, Judith and Friberg, Anders and Sch{\"a}fer, Martina and Briem, Hans and Raschke, Marian and Miyatake Ondozabal, Hideki and Buchmann, Bernd and Boemer, Ulf and Kreft, Bertolt and Hartung, Ingo V. and Offringa, Rienk},
  title={Discovery of BAY-405},
  subtitle={an azaindole-based MAP4K1 inhibitor for the enhancement of T-Cell immunity against cancer},
  year={2024},
  pages={17429-17453},
  language={eng},
  issn={1520-4804},
  volume={67},
  number={19},
  note={Online ver{\"o}ffentlicht: 27. September 2024 ; Gesehen am 14.03.2025},
  journal={Journal of medicinal chemistry},
  doi={10.1021/acs.jmedchem.4c01325},
}
@article{UBHD-68924168,
  author={Pinkert, Jessica and B{\"o}hm, Hans-Henning and Trautwein, Mark and Doecke, Wolf-Dietrich and Wessel, Florian and Ge, Yingzi and Gutierrez, Eva  Maria and Carretero, Rafael and Freiberg, Christoph and Gritzan, Uwe and Luetke-Eversloh, Merlin and Golfier, Sven and Ahsen, Oliver von and Volpin, Valentina and Sorrentino, Antonio and Rathinasamy, Anchana and Xydia, Maria and Lohmayer, Robert and Sax, Julian and Nur-Menevse, Ayse and Hussein, Abir and Stamova, Slava and Beckmann, Georg and Glueck, Julian Marius and Sch{\"o}nfeld, Dorian Leo and Weiske, J{\"o}rg and Zopf, Dieter and Offringa, Rienk and Kreft, Bertolt and Beckhove, Philipp and Willuda, J{\"o}rg},
  title={T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction},
  year={2022},
  pages={2008110},
  language={eng},
  issn={2162-402X},
  volume={11},
  number={1},
  note={Gesehen am 31.05.2022},
  journal={OncoImmunology},
  doi={10.1080/2162402X.2021.2008110},
}
@article{UBHD-68077024,
  author={Platten, Michael and Offringa, Rienk},
  title={Cancer immunotherapy},
  subtitle={exploiting neoepitopes},
  year={2015},
  pages={887-888},
  language={eng},
  issn={1748-7838},
  volume={25},
  number={8},
  note={Gesehen am 25.01.2017},
  journal={Cell research},
  doi={10.1038/cr.2015.66},
}
@article{UBHD-68656957,
  author={Poschke, Isabel and Faryna, Marta and Bergmann, Frank and Floßdorf, Michael and Lauenstein, Claudia and Hermes, Jennifer and Hinz, Ulf and Hank, Thomas and Ehrenberg, Karl Roland and Volkmar, Michael and Loewer, Martin and Glimm, Hanno and Hackert, Thilo and Sprick, Martin and H{\"o}fer, Thomas and Trumpp, Andreas and Halama, Niels and Hassel, Jessica C. and Strobel, Oliver and B{\"u}chler, Markus W. and Sahin, Ugur and Offringa, Rienk},
  title={Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma},
  year={2016},
  pages={12 S.},
  language={eng},
  issn={2162-402X},
  volume={5(2016},
  note={Published online: 29 Nov 2016 ; Gesehen am 03.11.2020},
  journal={OncoImmunology},
  doi={10.1080/2162402X.2016.1240859},
}
@article{UBHD-68187201,
  author={Poschke, Isabel and Floßdorf, Michael and Offringa, Rienk},
  title={Next-generation TCR sequencing},
  subtitle={a tool to understand T-cell infiltration in human cancers},
  year={2016},
  pages={384-386},
  language={eng},
  issn={2056-4538},
  volume={240},
  number={4},
  note={Gesehen am 07.11.2017},
  journal={The journal of pathology: clinical research},
  doi={10.1002/path.4800},
}
@article{UBHD-68643644,
  author={Poschke, Isabel and Hassel, Jessica C. and Rodriguez-Ehrenfried, Aaron and Lindner, Katharina A. M. and Heras-Murillo, Ignacio and Appel, Lena and Lehmann, Johanna and L{\"o}vgren, Tanja and Wickstr{\"o}m, Stina L. and Lauenstein, Claudia and Roth, Jasmin and K{\"o}nig, Anna-Katharina and Haanen, John B. A. G. and Berg, Joost van den and Kiessling, Rolf and Bergmann, Frank and Floßdorf, Michael and Strobel, Oliver and Offringa, Rienk},
  title={The outcome of ex vivo TIL expansion is highly influenced by spatial heterogeneity of the tumor T-cell repertoire and differences in intrinsic in vitro growth capacity between T-cell clones},
  year={2020},
  pages={4289-4301},
  language={eng},
  issn={1557-3265},
  volume={26},
  number={16},
  note={Gesehen am 06.10.2020},
  journal={Clinical cancer research},
  doi={10.1158/1078-0432.CCR-19-3845},
}
@article{UBHD-69293595,
  author={Salek, Mogjiborahman and F{\"o}rster, Jonas and Becker, Jonas Philipp and Meyer, Marten and Charoentong, Pornpimol and Lyu, Yanhong and Lindner, Katharina and Lotsch, Catharina and Volkmar, Michael and Momburg, Frank and Poschke, Isabel and Fr{\"o}hling, Stefan and Schmitz, Marc and Offringa, Rienk and Platten, Michael and J{\"a}ger, Dirk and Z{\"o}rnig, Inka and Riemer, Angelika},
  title={optiPRM},
  subtitle={a targeted immunopeptidomics LC-MS workflow with ultra-high sensitivity for the detection of mutation-derived tumor neoepitopes from limited input material},
  year={2024},
  pages={1-16},
  language={eng},
  issn={1535-9484},
  volume={23},
  note={Artikelversion: 5. September 2024 ; Gesehen am 23.01.2025},
  journal={Molecular & cellular proteomics},
  doi={10.1016/j.mcpro.2024.100825},
}
@article{UBHD-68640334,
  author={Schr{\"o}ter, Philipp and Hartmann, Laura and Osen, Wolfram and Baumann, Daniel and Offringa, Rienk and Eisel, David and Debus, J{\"u}rgen and Eichm{\"u}ller, Stefan B. and Rieken, Stefan},
  title={Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line},
  year={2020},
  pages={10 S.},
  language={eng},
  issn={2045-2322},
  volume={10(2020) Artikel-Nummer 686},
  number={10 Seiten},
  note={Gesehen am 25.09.2020},
  journal={Scientific reports},
  doi={10.1038/s41598-020-57456-2},
}
@article{UBHD-68463203,
  author={Sefrin, Julian Peter and Hillringhaus, Lars and Mundigl, Olaf and Mann, Karin and Ziegler-Landesberger, Doris and Seul, Heike and Tabares, Gloria and Knoblauch, Dominic and Leinenbach, Andreas and Friligou, Irene and Dziadek, Sebastian and Offringa, Rienk and Lifke, Valeria and Lifke, Alexander},
  title={Sensitization of tumors for attack by virus-specific CD8+ T-cells through antibody-mediated delivery of immunogenic T-cell epitopes},
  year={2019},
  pages={14 S.},
  language={eng},
  issn={1664-3224},
  volume={10(2019},
  note={Gesehen am 03.12.2019},
  journal={Frontiers in immunology},
  doi={10.3389/fimmu.2019.01962},
}
@article{UBHD-68942056,
  author={Sorrentino, Antonio and Menevse, Ayse Nur and Michels, Tillmann and Volpin, Valentina and Durst, Franziska Christine and Sax, Julian and Xydia, Maria and Hussein, Abir and Stamova, Slava and Spoerl, Steffen and Heuschneider, Nicole and Muehlbauer, Jasmin and Jeltsch, Katharina Marlene and Rathinasamy, Anchana and Werner-Klein, Melanie and Breinig, Marco and Mikietyn, Damian and Kohler, Christian and Poschke, Isabel and Purr, Sabrina and Reidell, Olivia and Freire, Catarina Martins and Offringa, Rienk and Gebhard, Claudia and Spang, Rainer and Rehli, Michael and Boutros, Michael and Schmidl, Christian and Khandelwal, Nisit and Beckhove, Philipp},
  title={Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation},
  year={2022},
  pages={1-18},
  language={eng},
  issn={2051-1426},
  volume={10},
  note={Gesehen am 14.07.2022},
  journal={Journal for ImmunoTherapy of Cancer},
  doi={10.1136/jitc-2021-004258},
}
@article{UBHD-69071626,
  author={Steinfass, Tamara and Poelchen, Juliane and Sun, Qian and Mastrogiulio, Giovanni and Novak, Daniel and Vierthaler, Marlene and Pardo, Sandra and Federico, Aniello and H{\"u}ser, Laura and Hielscher, Thomas and Carretero, Rafael and Offringa, Rienk and Altevogt, Peter and Umansky, Viktor and Utikal, Jochen},
  title={Secretogranin II influences the assembly and function of MHC class I in melanoma},
  year={2023},
  pages={1-6},
  language={eng},
  issn={2162-3619},
  volume={12},
  number={Artikel-ID 29},
  note={Gesehen am 03.05.2023},
  journal={Experimental hematology & oncology},
  doi={10.1186/s40164-023-00387-1},
}
@article{UBHD-69126384,
  author={Sun, Rui and Meng, Zibo and Lee, Hyeyoon and Offringa, Rienk and Niehrs, Christof},
  title={ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation},
  year={2023},
  pages={739-752.e8},
  language={eng},
  issn={2451-9456},
  volume={30},
  number={7 vom: Juli},
  note={Online verf{\"u}gbar: 14. Juni 2023, Artikelversion: 20. Juli 2023 ; Gesehen am 04.10.2023},
  journal={Cell chemical biology},
  doi={10.1016/j.chembiol.2023.05.010},
}
@article{UBHD-69239050,
  author={Tan, Chin Leng and Lindner, K. and Boschert, T. and Meng, Zibo and Rodriguez Ehrenfried, Aaron and De Roia, Alice and Haltenhof, G. and Faenza, A. and Imperatore, F. and Bunse, Lukas and Lindner, J. M. and Harbottle, R. P. and Ratliff, Miriam and Offringa, Rienk and Poschke, Isabel and Platten, Michael and Green, Edward W.},
  title={Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy},
  year={2024},
  pages={1-9},
  language={eng},
  issn={1546-1696},
  note={Gesehen am 31.07.2024},
  journal={Nature biotechnology},
  doi={10.1038/s41587-024-02161-y},
}
@article{UBHD-68611660,
  author={Zurli, Vanessa and Montecchi, Tommaso and Heilig, Raphael and Poschke, Isabel and Volkmar, Michael and Wimmer, Giuliana and Boncompagni, Gioia and Turacchio, Gabriele and D’Elios, Mario Milco and Campoccia, Giuseppe and Resta, Nicoletta and Offringa, Rienk and Fischer, Roman and Acuto, Oreste and Baldari, Cosima Tatiana and Kabanova, Anna},
  title={Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells},
  year={2020},
  pages={? S.},
  language={eng},
  issn={1937-9145},
  volume={13(2020},
  note={Gesehen am 02.07.2020},
  journal={Science signaling},
  doi={10.1126/scisignal.aaz1965},
}