@article{UBHD-68378323, author={Abelson, Sagi and Kaaks, Rudolf and Kr{\"a}mer, Alwin}, title={Prediction of acute myeloid leukaemia risk in healthy individuals}, year={2018}, pages={400-422}, language={eng}, issn={1476-4687}, volume={559}, number={7714}, note={Gesehen am 03.04.2019}, journal={Nature}, doi={10.1038/s41586-018-0317-6}, } @article{UBHD-68620249, author={Alsara, Mohammad and L{\"o}ffler, Harald and Fechter, Anne and Bartek, Jiri and Kr{\"a}mer, Alwin}, title={Cep63 recruits Cdk1 to the centrosome}, subtitle={letter}, year={2015}, pages={777-778}, language={eng}, issn={1538-7445}, volume={75}, number={4}, note={Gesehen am 23.07.2020}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-14-3431}, } @article{UBHD-68254794, author={Anderhub, Simon and Kr{\"a}mer, Alwin and Maier, Bettina}, title={Centrosome amplification in tumorigenesis}, year={2012}, pages={8-17}, language={eng}, issn={1872-7980}, volume={322}, number={1}, note={Gesehen am 25.05.2018}, journal={Cancer letters}, doi={10.1016/j.canlet.2012.02.006}, } @article{UBHD-68308807, author={Balß, J{\"o}rg and Pusch, Stefan and Herold-Mende, Christel and Kr{\"a}mer, Alwin and Langhans, Claus-Dieter and Okun, J{\"u}rgen G. and Deimling, Andreas von}, title={Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate}, year={2012}, pages={883-891}, language={eng}, issn={1432-0533}, volume={124}, number={6}, note={Gesehen am 25.09.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-012-1060-y}, } @article{UBHD-68621767, author={Balß, J{\"o}rg and Bochtler, Tilmann and Okun, J{\"u}rgen G. and Pusch, Stefan and Ho, Anthony Dick and Deimling, Andreas von and Kr{\"a}mer, Alwin and Heilig, Christoph E.}, title={Pretreatment d -2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia}, year={2016}, pages={782-788}, language={eng}, issn={1476-5551}, volume={30}, number={4}, note={Published: 19 November 2015 ; Gesehen am 29.07.2020}, journal={Leukemia}, doi={10.1038/leu.2015.317}, } @article{UBHD-68426769, author={Bixby, Dale and Noppeney, Richard and Lin, Tara L. and Cortes, Jorge and Krauter, J{\"u}rgen and Yee, Karen and Medeiros, Bruno C. and Kr{\"a}mer, Alwin and Assouline, Sarit and Fiedler, Walter and Dimier, Natalie and Simmons, Brian P. and Riehl, Todd and Colburn, Dawn}, title={Safety and efficacy of vismodegib in relapsed/refractory acute myeloid leukaemia}, subtitle={results of a phase Ib trial}, year={2019}, pages={595-598}, language={eng}, issn={1365-2141}, volume={185}, number={3}, note={First online: 11 September 2018 ; Gesehen am 04.09.2019}, journal={British journal of haematology}, doi={10.1111/bjh.15571}, } @article{UBHD-68314282, author={Bochtler, Tilmann and Kirsch, Michael and Klingm{\"u}ller, Ursula and Ho, Anthony Dick and Kr{\"a}mer, Alwin}, title={Centrosomal targeting of tyrosine kinase activity does not enhance oncogenicity in chronic myeloproliferative disorders}, year={2012}, pages={728-735}, language={eng}, issn={1476-5551}, volume={26}, number={4}, note={Gesehen am 11.10.2018 ; Published online 21 October 2011}, journal={Leukemia}, doi={10.1038/leu.2011.283}, } @article{UBHD-68666390, author={Bochtler, Tilmann and St{\"o}lzel, Friedrich and Heilig, Christoph E. and Kunz, Christina and Mohr, Brigitte and Jauch, Anna and Janssen, Johannes W. G. and Kramer, Michael and Benner, Axel and Bornh{\"a}user, Martin and Ho, Anthony Dick and Ehninger, Gerhard and Schaich, Markus and Kr{\"a}mer, Alwin}, title={Clonal heterogeneity as detected by metaphase karyotyping is an indicator of poor prognosis in acute myeloid leukemia}, year={2013}, pages={3898-3905}, language={eng}, issn={1527-7755}, volume={31}, number={31}, note={Gesehen am 27.11.2020}, journal={Journal of clinical oncology}, doi={10.1200/JCO.2013.50.7921}, } @article{UBHD-68447396, author={Bochtler, Tilmann and Endris, Volker and Leichsenring, Jonas and Neumann, Olaf and Volckmar, Anna-Lena and Kirchner, Martina and Allg{\"a}uer, Michael and Schirmacher, Peter and Kr{\"a}mer, Alwin and Stenzinger, Albrecht}, title={Comparative genetic profiling aids diagnosis and clinical decision making in challenging cases of CUP syndrome}, year={2019}, pages={2963-2973}, language={eng}, issn={1097-0215}, volume={145}, number={11}, note={Gesehen am 29.10.2019}, journal={International journal of cancer}, doi={10.1002/ijc.32316}, } @article{UBHD-68493706, author={Bochtler, Tilmann and Merz, Maximilian and Hielscher, Thomas and Granzow, Martin and Hoffmann, Korbinian and Kr{\"a}mer, Alwin and Raab, Marc-Steffen and Hillengaß, Jens and Seckinger, Anja and Kimmich, Christoph and Dittrich, Tobias and M{\"u}ller-Tidow, Carsten and Hose, Dirk and Goldschmidt, Hartmut and Hegenbart, Ute and Jauch, Anna and Sch{\"o}nland, Stefan}, title={Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma}, year={2018}, pages={2607-2618}, language={eng}, issn={2473-9537}, volume={2}, number={20}, note={Gesehen am 26.02.2020}, journal={Blood advances}, doi={10.1182/bloodadvances.2018023200}, } @article{UBHD-68319534, author={Bochtler, Tilmann and L{\"o}ffler, Harald and Kr{\"a}mer, Alwin}, title={Diagnosis and management of metastatic neoplasms with unknown primary}, year={2018}, pages={199-206}, language={eng}, issn={1930-1111}, volume={35}, number={3}, note={Gesehen am 22.10.2018 ; Available online 26 November 2017}, journal={Seminars in diagnostic pathology}, doi={10.1053/j.semdp.2017.11.013}, } @article{UBHD-68400702, author={Bochtler, Tilmann and Kr{\"a}mer, Alwin}, title={Does cancer of unknown primary (CUP) truly exist as a distinct cancer entity?}, year={2019}, pages={8 S.}, language={eng}, issn={2234-943X}, volume={9(2019) Artikel-Nummer 402}, number={8 Seiten}, note={Gesehen am 24.06.2019}, journal={Frontiers in oncology}, doi={10.3389/fonc.2019.00402}, } @article{UBHD-68493639, author={Bochtler, Tilmann and Haag, Georg Martin and Schott, Sarah and Kloor, Matthias and Kr{\"a}mer, Alwin and M{\"u}ller-Tidow, Carsten}, title={Hematological malignancies in adults with a family predisposition}, year={2018}, pages={848-854}, language={eng}, issn={1866-0452}, volume={115}, number={50}, note={Gesehen am 26.02.2020}, journal={Deutsches {\"A}rzteblatt international}, doi={10.3238/arztebl.2018.0848}, } @article{UBHD-68493065, author={Bochtler, Tilmann and Endris, Volker and Reiling, Anna and Leichsenring, Jonas and Schweiger, Michal-Ruth and Klein, Sebastian and St{\"o}gbauer, Fabian and Goeppert, Benjamin and Schirmacher, Peter and Kr{\"a}mer, Alwin and Stenzinger, Albrecht}, title={Integrated histogenetic analysis reveals BAP1-mutated epithelioid mesothelioma in a patient with cancer of unknown primary}, year={2018}, pages={677-682}, language={eng}, issn={1540-1413}, volume={16}, number={6}, note={Gesehen am 25.02.2020}, journal={Journal of the National Comprehensive Cancer Network}, doi={10.6004/jnccn.2018.7012}, } @article{UBHD-68679921, author={Bochtler, Tilmann and Reiling, Anna and Endris, Volker and Hielscher, Thomas and Volckmar, Anna-Lena and Neumann, Olaf and Kirchner, Martina and Budczies, Jan and Heukamp, Lukas C. and Leichsenring, Jonas and Allg{\"a}uer, Michael and Kazdal, Daniel and L{\"o}ffler, Harald and Weichert, Wilko and Schirmacher, Peter and Stenzinger, Albrecht and Kr{\"a}mer, Alwin}, title={Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary}, year={2020}, pages={3053-3064}, language={eng}, issn={1097-0215}, volume={146}, number={11}, note={Gesehen am 14.01.2021}, journal={International journal of cancer}, doi={10.1002/ijc.32882}, } @article{UBHD-69291044, author={Bochtler, Tilmann and Christopoulos, Petros and Schlamp, Kai and Winkler, Frank and Kr{\"a}mer, Alwin}, title={Management of a pregnant ALK-positive lung cancer patient with alectinib-induced pneumonitis and bilateral globus pallidus necrosis postpartum}, year={2024}, pages={72-76}, language={eng}, issn={1938-0690}, volume={25}, number={1 vom: Jan.}, note={Online ver{\"o}ffentlicht: 30. August 2023 ; Gesehen am 15.01.2025}, journal={Clinical lung cancer}, doi={10.1016/j.cllc.2023.08.016}, } @article{UBHD-68304973, author={Bochtler, Tilmann and Granzow, Martin and Kartal-Kaess, Mutlu and Hinderhofer, Katrin and Heilig, Christoph E. and Endris, Volker and Kirchner, Martina and Stenzinger, Albrecht and Ho, Anthony Dick and Jauch, Anna and Kr{\"a}mer, Alwin}, title={Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia}, year={2017}, pages={1333-1342}, language={eng}, issn={1528-0020}, volume={129}, number={10}, note={Gesehen am 14.09.2018}, journal={Blood}, doi={10.1182/blood-2016-09-738161}, } @article{UBHD-68392179, author={Bochtler, Tilmann and Kartal-Kaess, Mutlu and Granzow, Martin and Herold-Mende, Christel and Jauch, Anna and Kr{\"a}mer, Alwin}, title={Micronucleus formation in human cancer cells is biased by chromosome size}, year={2019}, pages={392-395}, language={eng}, issn={1098-2264}, volume={58}, number={6}, note={First published: 08 November 2018 ; Gesehen am 22.05.2019}, journal={Genes, chromosomes & cancer}, doi={10.1002/gcc.22707}, } @article{UBHD-68107702, author={Bochtler, Tilmann and Fr{\"o}hling, Stefan and Kr{\"a}mer, Alwin}, title={Role of chromosomal aberrations in clonal diversity and progression of acute myeloid leukemia}, year={2015}, pages={1243-1252}, language={eng}, issn={1476-5551}, volume={29}, number={6}, note={Gesehen am 06.04.2017}, journal={Leukemia}, doi={10.1038/leu.2015.32}, } @article{UBHD-68304984, author={Bochtler, Tilmann and Kr{\"a}mer, Alwin}, title={Systemtherapie prognostisch ung{\"u}nstiger CUP-Syndrome}, subtitle={Adeno- und undifferenzierte Karzinome}, year={2017}, pages={1000-1005}, language={ger}, issn={1433-0415}, volume={23}, number={12}, note={Gesehen am 14.09.2018}, journal={Der Onkologe}, doi={10.1007/s00761-017-0206-x}, } @article{UBHD-68378199, author={Bonin, Malte von and Kr{\"a}mer, Alwin}, title={JAM-C expression as a biomarker to predict outcome of patients with acute myeloid leukemia-letter}, year={2018}, pages={6339-6341}, language={eng}, issn={1538-7445}, volume={78}, number={21}, note={Gesehen am 02.04.2019}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-18-0642}, } @article{UBHD-69262473, author={Budczies, Jan and Kazdal, Daniel and Menzel, Michael and Beck, Susanne and Kluck, Klaus and Altb{\"u}rger, Christian and Schwab, Constantin and Allg{\"a}uer, Michael and Ahadova, Aysel and Kloor, Matthias and Schirmacher, Peter and Peters, Solange and Kr{\"a}mer, Alwin and Christopoulos, Petros and Stenzinger, Albrecht}, title={Tumour mutational burden}, subtitle={clinical utility, challenges and emerging improvements}, year={2024}, pages={725-742}, language={eng}, issn={1759-4782}, volume={21}, number={10 vom: Okt.}, note={Zuerst ver{\"o}ffentlicht: 27. August 2024 ; Gesehen am 15.10.2024}, journal={Nature reviews}, doi={10.1038/s41571-024-00932-9}, } @book{UBHD-67905205, editor={Kr{\"a}mer, Alwin and L{\"o}ffler, Harald}, title={Cancer of unknown primary}, publisher={Springer}, address={Cham}, year={2016}, pages={VI, 194 Seiten}, language={eng}, isbn={978-3-319-22580-7}, library={UB [Signatur: UBN/XH 2000 K89]}, } @book{UBHD-67957356, editor={Kr{\"a}mer, Alwin and L{\"o}ffler, Harald}, title={Cancer of unknown primary}, publisher={Springer}, address={Cham}, year={2016}, pages={Online-Ressource (VI, 194 p. 33 illus., 30 illus. in color, online resource)}, language={eng}, isbn={978-3-319-22581-4}, series={SpringerLink : B{\"u}cher}, note={Includes bibliographical references at the end of each chapters}, doi={10.1007/978-3-319-22581-4}, } @article{UBHD-68935237, author={Castiel, Asher and Danieli, Michal Mark and David, Ahuvit and Moshkovitz, Sharon and Aplan, Peter D. and Kirsch, Ilan R. and Brandeis, Michael and Kr{\"a}mer, Alwin and Izraeli, Shai}, title={The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr}, year={2011}, pages={532-539}, language={eng}, issn={1477-9137}, volume={124}, number={4}, note={Gesehen am 28.06.2022}, journal={Journal of cell science}, doi={10.1242/jcs.079731}, } @article{UBHD-69068365, author={Castilhos, Juliana de and Zamir, Eli and Wenz, Theresa and Rohrbach, Roman and Schmidt, Sabine and Hengler, Silvana and Schumacher, Hanna and Neubauer, Melanie and Kunz, Sabrina and M{\"u}ller-Esch, Tonia and Hiergeist, Andreas and Geßner, André and Khalid, Dina and Gaiser, Rogier and Cullin, Nyssa and Papagiannarou, Stamatia M. and Beuthien-Baumann, Bettina and Kr{\"a}mer, Alwin and Bartenschlager, Ralf and J{\"a}ger, Dirk and M{\"u}ller, Michael and Herth, Felix and Duerschmied, Daniel and Schneider, Jochen and Schmid, Roland M. and Eberhardt, Johann F. and Khodamoradi, Yascha and Vehreschild, Maria J. G. T. and Teufel, Andreas and Ebert, Matthias and Hau, Peter and Salzberger, Bernd and Schnitzler, Paul and Poeck, Hendrik and Elinav, Eran and Merle, Uta and Stein-Th{\"o}ringer, Christoph}, title={Correction to: Severe dysbiosis and specific haemophilus and neisseria signatures as hallmarks of the oropharyngeal microbiome in critically Ill coronavirus disease 2019 (COVID-19) patients}, year={2022}, pages={185}, language={eng}, issn={1537-6591}, volume={75}, number={1}, note={Online ver{\"o}ffentlicht: 10. Mai 2022 ; Gesehen am 24.04.2023}, journal={Clinical infectious diseases}, doi={10.1093/cid/ciac254}, } @article{UBHD-69068328, author={Castilhos, Juliana de and Zamir, Eli and Wenz, Theresa and Rohrbach, Roman and Schmidt, Sabine and Hengler, Silvana and Schumacher, Hanna and Neubauer, Melanie and Kunz, Sabrina and M{\"u}ller-Esch, Tonia and Hiergeist, Andreas and Geßner, André and Khalid, Dina and Gaiser, Rogier and Cullin, Nyssa and Papagiannarou, Stamatia M. and Beuthien-Baumann, Bettina and Kr{\"a}mer, Alwin and Bartenschlager, Ralf and J{\"a}ger, Dirk and M{\"u}ller, Michael and Herth, Felix and Duerschmied, Daniel and Schneider, Jochen and Schmid, Roland M. and Eberhardt, Johann F. and Khodamoradi, Yascha and Vehreschild, Maria J. G. T. and Teufel, Andreas and Ebert, Matthias and Hau, Peter and Salzberger, Bernd and Schnitzler, Paul and Poeck, Hendrik and Elinav, Eran and Merle, Uta and Stein-Th{\"o}ringer, Christoph}, title={Severe dysbiosis and specific haemophilus and neisseria signatures as hallmarks of the oropharyngeal microbiome in critically Ill coronavirus disease 2019 (COVID-19) patients}, year={2022}, pages={e1063-e1071}, language={eng}, issn={1537-6591}, volume={75}, number={1}, note={Online ver{\"o}ffentlicht: 25. Oktober 2021 ; Gesehen am 24.04.2023}, journal={Clinical infectious diseases}, doi={10.1093/cid/ciab902}, } @article{UBHD-68921082, author={Cazzola, Anna and Jauch, Anna and Kr{\"a}mer, Alwin}, title={TP53 deficiency permits chromosome abnormalities and karyotype heterogeneity in acute myeloid leukemia}, year={2019}, pages={2619-2627}, language={eng}, issn={1476-5551}, volume={33}, number={11}, note={Gesehen am 23.03.2020}, journal={Leukemia}, doi={10.1038/s41375-019-0550-5}, } @article{UBHD-68124395, author={Chaturvedi, Anuhar and Pusch, Stefan and Stichel, Damian and Bochtler, Tilmann and Ho, Anthony Dick and Deimling, Andreas von and Rippe, Karsten and Kr{\"a}mer, Alwin}, title={Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo}, year={2017}, pages={2020-2028}, language={eng}, issn={1476-5551}, volume={31}, number={10}, note={Gesehen am 15.11.2017}, journal={Leukemia}, doi={10.1038/leu.2017.46}, } @book{UBHD-68351482, editor={Kr{\"a}mer, Alwin}, title={Comprehensive Genomic Profiling}, subtitle={Chancen der molekularen Diagnostik am Beispiel des Portfolios von Foundation Medicine®}, publisher={Thieme}, address={Stuttgart ; New York}, year={2018}, pages={11 Seiten}, language={ger}, number={ARRAY(0x555d5b64ba70)}, series={Drug report}, } @book{UBHD-68395577, editor={Kr{\"a}mer, Alwin}, title={Comprehensive genomic profiling}, subtitle={Chancen der molekularen Diagnostik am Beispiel des Portfolios von Foundation Medicine}, publisher={Thieme}, address={Stuttgart}, year={2018}, pages={11 Seiten}, language={ger}, number={ARRAY(0x555d5b69dc18)}, series={Drug report}, } @article{UBHD-68403015, author={Cortés, Jorge Eduardo and Kr{\"a}mer, Alwin}, title={Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia}, subtitle={an open-label, multicentre, single-arm, phase 2 trial}, year={2018}, pages={889-903}, language={eng}, issn={1474-5488}, volume={19}, number={7}, note={Gesehen am 01.07.2019}, journal={The lancet}, doi={10.1016/S1470-2045(18)30240-7}, } @article{UBHD-68425892, author={Cortés, Jorge Eduardo and Khaled, Samer and Martinelli, Giovanni and Perl, Alexander E and Ganguly, Siddhartha and Russell, Nigel and Kr{\"a}mer, Alwin and Dombret, Hervé and Hogge, Donna and Jonas, Brian A and Leung, Anskar Yu-Hung and Mehta, Priyanka and Montesinos, Pau and Radsak, Markus and Sica, Simona and Arunachalam, Meena and Holmes, Melissa and Kobayashi, Ken and Namuyinga, Ruth and Ge, Nanxiang and Yver, Antoine and Zhang, Yufen and Levis, Mark J}, title={Quizartinib versus salvage chemotherapy in relapsed or refractory FLT3-ITD acute myeloid leukaemia (QuANTUM-R)}, subtitle={a multicentre, randomised, controlled, open-label, phase 3 trial}, year={2019}, pages={984-997}, language={eng}, issn={1474-5488}, volume={20}, number={7}, note={Gesehen am 02.09.2019}, journal={The lancet}, doi={10.1016/S1470-2045(19)30150-0}, } @article{UBHD-68309713, author={Cosenza, Marco R. and Cazzola, Anna and Rossberg, Annik and Konotop, Gleb and Bausch, Elena and Slynko, Alla and Holland-Letz, Tim and Raab, Marc-Steffen and Dubash, Taronish Dorab and Glimm, Hanno and Herold-Mende, Christel and Kr{\"a}mer, Alwin}, title={Asymmetric centriole numbers at spindle poles cause chromosome missegregation in cancer}, year={2017}, pages={1906-1920}, language={eng}, issn={2211-1247}, volume={20}, number={8}, note={Gesehen am 27.09.2018}, journal={Cell reports}, doi={10.1016/j.celrep.2017.08.005}, } @article{UBHD-68573255, author={Cosenza, Marco R. and Kr{\"a}mer, Alwin}, title={Centrosome amplification, chromosomal instability and cancer}, subtitle={mechanistic, clinical and therapeutic issues}, year={2016}, pages={105-126}, language={eng}, issn={1573-6849}, volume={24}, number={1}, note={Published: 08 December 2015 ; Gesehen am 05.05.2020}, journal={Chromosome research}, doi={10.1007/s10577-015-9505-5}, } @article{UBHD-68573889, author={Daly, Owen M. and Gaboriau, David and Karakaya, Kadin and King, Sinéad and Dantas, Tiago J. and Lalor, Pierce and Dockery, Peter and Kr{\"a}mer, Alwin and Morrison, Ciaran G.}, title={CEP164-null cells generated by genome editing show a ciliation defect with intact DNA repair capacity}, year={2016}, pages={1769-1774}, language={eng}, issn={1477-9137}, volume={129}, number={9}, note={Gesehen am 06.05.2020}, journal={Journal of cell science}, doi={10.1242/jcs.186221}, } @article{UBHD-69084352, author={Delorme, Stefan and Kr{\"a}mer, Alwin}, title={Das große R{\"a}tsel - ein zweiter Blick}, year={2023}, pages={327-328}, language={ger}, issn={2731-7056}, volume={63}, number={5 vom: Apr.}, note={Gesehen am 12.06.2023}, journal={Die Radiologie}, doi={10.1007/s00117-023-01142-7}, } @article{UBHD-68929714, author={Dietrich, Sascha and Andrulis, Mindaugas and Hegenbart, Ute and Schmitt, Thomas and Bellos, Frauke and Martens, Uwe M. and Meißner, Julia and Kr{\"a}mer, Alwin and Ho, Anthony Dick and Dreger, Peter}, title={Blastic plasmacytoid dendritic cell neoplasia (BPDC) in elderly patients}, subtitle={results of a treatment algorithm employing allogeneic stem cell transplantation with moderately reduced conditioning intensity}, year={2011}, pages={1250-1254}, language={eng}, issn={1523-6536}, volume={17}, number={8}, note={Gesehen am 10.06.2022}, journal={Biology of blood and marrow transplantation}, doi={10.1016/j.bbmt.2010.12.706}, } @article{UBHD-68121908, author={Dietrich, Sascha and Radujković, Aleksandar and Kr{\"a}mer, Alwin and Hegenbart, Ute and Ho, Anthony Dick and Dreger, Peter and Luft, Thomas}, title={Pretransplant metabolic distress predicts relapse of acute myeloid leukemia after allogeneic stem cell transplantation}, year={2015}, pages={1065-1071}, language={eng}, issn={1534-6080}, volume={99}, number={5}, note={Gesehen am 22.05.2017}, journal={Transplantation}, doi={10.1097/TP.0000000000000471}, } @article{UBHD-68378558, author={D{\"o}hner, Hartmut and M{\"u}ller-Tidow, Carsten and L{\"u}bbert, Michael and Fiedler, Walter and Kr{\"a}mer, Alwin and Westermann, J{\"o}rg and Bug, Gesine and Schlenk, Richard Friedrich and Krug, Utz and Goeldner, Rainer-Georg and Hilbert, James and Taube, Tillmann and Ottmann, Oliver G.}, title={A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia}, year={2019}, pages={583-587}, language={eng}, issn={1365-2141}, volume={185}, number={3}, note={Ver{\"o}ffentlicht: 19 November 2018 ; Gesehen am 04.04.2019}, journal={British journal of haematology}, doi={10.1111/bjh.15563}, } @article{UBHD-68620803, author={D{\"o}hner, Hartmut and L{\"u}bbert, Michael and Fiedler, Walter and Fouillard, Loic and Haaland, Alf and Brandwein, Joseph M. and Lepretre, Stephane and Reman, Oumedaly and Turlure, Pascal and Ottmann, Oliver G. and M{\"u}ller-Tidow, Carsten and Kr{\"a}mer, Alwin and Raffoux, Emmanuel and D{\"o}hner, Konstanze and Schlenk, Richard F. and Voß, Florian and Taube, Tillmann and Fritsche, Holger and Maertens, Johan}, title={Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy}, year={2014}, pages={1426-1433}, language={eng}, issn={1528-0020}, volume={124}, number={9}, note={Gesehen am 27.07.2020}, journal={Blood}, doi={10.1182/blood-2014-03-560557}, } @article{UBHD-68920462, author={Duesberg, Peter and Li, Ruhong and Rasnick, David and Rausch, Charlotte and Willer, Andreas and Kr{\"a}mer, Alwin and Yerganian, George and Hehlmann, R{\"u}diger}, title={Aneuploidy precedes and segregates with chemical carcinogenesis}, year={2000}, pages={83-93}, language={eng}, issn={1873-4456}, volume={119}, number={2}, note={Gesehen am 19.05.2022}, journal={Cancer genetics and cytogenetics}, doi={10.1016/S0165-4608(99)00236-8}, } @article{UBHD-68771704, author={Eckardt, Jan-Niklas and Stasik, Sebastian and Kramer, Michael and R{\"o}llig, Christoph and Kr{\"a}mer, Alwin and Scholl, Sebastian and Hochhaus, Andreas and Crysandt, Martina and Br{\"u}mmendorf, Tim H. and Naumann, Ralph and Steffen, Bj{\"o}rn and Kunzmann, Volker and Einsele, Hermann and Schaich, Markus and Burchert, Andreas and Neubauer, Andreas and Sch{\"a}fer-Eckart, Kerstin and Schliemann, Christoph and Krause, Stefan W. and Herbst, Regina and H{\"a}nel, Mathias and Frickhofen, Norbert and Noppeney, Richard and Kaiser, Ulrich and Baldus, Claudia D. and Kaufmann, Martin and Rácil, Zdenek and Platzbecker, Uwe and Berdel, Wolfgang E. and Mayer, Jiří and Serve, Hubert and M{\"u}ller-Tidow, Carsten and Ehninger, Gerhard and St{\"o}lzel, Friedrich and Kroschinsky, Frank and Schetelig, Johannes and Bornh{\"a}user, Martin and Thiede, Christian and Middeke, Jan Moritz}, title={Loss-of-function mutations of BCOR are an independent marker of adverse outcomes in intensively treated patients with acute myeloid leukemia}, year={2021}, pages={1-15}, language={eng}, issn={2072-6694}, volume={13}, note={Gesehen am 18.08.2021}, journal={Cancers}, doi={10.3390/cancers13092095}, } @article{UBHD-68935522, author={Eckardt, Jan-Niklas and St{\"o}lzel, Friedrich and Kunadt, Desiree and R{\"o}llig, Christoph and Stasik, Sebastian and Wagenf{\"u}hr, Lisa and J{\"o}hrens, Korinna and Kuithan, Friederike and Kr{\"a}mer, Alwin and Scholl, Sebastian and Hochhaus, Andreas and Crysandt, Martina and Br{\"u}mmendorf, Tim H. and Naumann, Ralph and Steffen, Bj{\"o}rn and Kunzmann, Volker and Einsele, Hermann and Schaich, Markus and Burchert, Andreas and Neubauer, Andreas and Sch{\"a}fer-Eckart, Kerstin and Schliemann, Christoph and Krause, Stefan W. and Herbst, Regina and H{\"a}nel, Mathias and Hanoun, Maher and Kaiser, Ulrich and Kaufmann, Martin and Rácil, Zdenek and Mayer, Jiri and Kroschinsky, Frank and Berdel, Wolfgang E. and Ehninger, Gerhard and Serve, Hubert and M{\"u}ller-Tidow, Carsten and Platzbecker, Uwe and Baldus, Claudia D. and Schetelig, Johannes and Bornh{\"a}user, Martin and Thiede, Christian and Middeke, Jan Moritz}, title={Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations}, year={2022}, pages={1-13}, language={eng}, issn={1756-8722}, volume={15}, number={Artikel-ID 60}, note={Published: 13 May 2022 ; Gesehen am 28.06.2022}, journal={Journal of hematology & oncology}, doi={10.1186/s13045-022-01267-7}, } @article{UBHD-68720203, author={Figueroa Vazquez, Vianihuini and Ko, Jonathan and Breunig, Christian and Baumann, Anja and Giesen, Nicola and Palfi, Aniko and M{\"u}ller, Christoph and Lutz, Christian and Hechler, Torsten and Kulke, Michael and M{\"u}ller-Tidow, Carsten and Kr{\"a}mer, Alwin and Goldschmidt, Hartmut and Pahl, Andreas and Raab, Marc-Steffen}, title={HDP-101, an anti-BCMA antibody-drug conjugate, safely delivers amanitin to induce cell death in proliferating and resting multiple myeloma cells}, year={2021}, pages={367-378}, language={eng}, issn={1538-8514}, volume={20}, number={2}, note={Published online first: December 9, 2020 ; Gesehen am 08.09.2021}, journal={Molecular cancer therapeutics}, doi={10.1158/1535-7163.MCT-20-0287}, } @article{UBHD-68729781, author={Folprecht, Gunnar and Trautmann, Karolin and Stein, Alexander and Huebner, Gerdt and Stahl, Michael and Kasper, Stefan and Kretzschmar, Albrecht and K{\"o}hne, Claus-Henning and Gr{\"u}nwald, Viktor and Hofheinz, Ralf-Dieter and Sch{\"u}tte, Katharina and L{\"o}ffler, Harald and Bokemeyer, Carsten and Kr{\"a}mer, Alwin}, title={Adding cetuximab to paclitaxel and carboplatin for first-line treatment of carcinoma of unknown primary (CUP)}, subtitle={results of the Phase 2 AIO trial PACET-CUP}, year={2021}, pages={721-727}, language={eng}, issn={1532-1827}, volume={124}, number={4}, note={Gesehen am 28.04.2021 ; Published online: 25 November 2020}, journal={British journal of cancer}, doi={10.1038/s41416-020-01141-8}, } @article{UBHD-69343179, author={Fr{\"u}hauf, Stefan and Veldwijk, Marlon Romano and Kr{\"a}mer, Alwin and Haas, Rainer and Zeller, W. Jens}, title={Delineation of cell cycle state and correlation to adhesion molecule expression of human CD34+ cells from steady-state bone marrow and peripheral blood mobilized following G-CSF-supported chemotherapy}, year={1998}, pages={271-279}, language={eng}, issn={1549-4918}, volume={16}, number={4}, note={Gesehen am 08.05.2025}, journal={Stem cells}, doi={10.1002/stem.160271}, } @article{UBHD-69106850, author={Gaidzik, Verena Ingeborg and Paschka, Peter and Schlenk, Richard Friedrich and Weber, Daniela and Fr{\"o}hling, Stefan and Kr{\"a}mer, Alwin and W{\"a}sch, Ralph and Westermann, J{\"o}rg and Mayer, Karin and Wit, Maike de and Fiedler, Walter and Benner, Axel and Heuser, Michael and Thol, Felicitas and D{\"o}hner, Konstanze and Ganser, Arnold and D{\"o}hner, Hartmut}, title={Palbociclib in acute Leukemias with KMT2A-rearrangement}, subtitle={results of AMLSG 23-14 trial}, year={2023}, pages={1-4}, language={eng}, issn={2572-9241}, volume={7}, note={Gesehen am 07.08.2023}, journal={HemaSphere}, doi={10.1097/HS9.0000000000000877}, } @article{UBHD-68724628, author={Ganguly, Siddhartha and Cortes, Jorge E. and Kr{\"a}mer, Alwin and Levis, Mark J. and Martinelli, Giovanni and Perl, Alexander E. and Russell, Nigel H. and Arunachalam, Meena and Santos, Cedric Dos and Gammon, Guy and Lesegretain, Arnaud and Mires, Derek E. and Pham, Hoang and Wang, Yibin and Khaled, Samer K.}, title={Clinical outcomes in patients with FLT3-ITD-mutated relapsed/refractory acute myelogenous leukemia undergoing hematopoietic stem cell transplantation after quizartinib or salvage chemotherapy in the QuANTUM-R trial}, year={2021}, pages={153-162}, language={eng}, issn={2666-6367}, volume={27}, number={2}, note={Available online 21 December 2020 ; Gesehen am 20.04.2021}, journal={Transplantation and cellular therapy}, doi={10.1016/j.bbmt.2020.09.036}, } @article{UBHD-68877163, author={Goldschmidt, Hartmut and Cremer, Friedrich Walter and M{\"o}hler, Thomas and Kr{\"a}mer, Alwin and G{\"o}rner, Martin and Egerer, Gerlinde and Ho, Anthony Dick}, title={Therapy of multiple myeloma}, year={2002}, pages={141-144}, language={eng}, issn={1613-9089}, volume={1}, number={3}, note={Gesehen am 11.02.2022}, journal={The Chinese-german journal of clinical oncology}, doi={10.1007/BF02851708}, } @article{UBHD-68242302, author={Heidrich, Katharina and Kr{\"a}mer, Alwin}, title={Allogeneic hematopoietic cell transplantation in intermediate risk acute myeloid leukemia negative for FLT3-ITD, NPM1- or biallelic CEBPA mutations}, year={2017}, pages={2793-2798}, language={eng}, issn={1569-8041}, volume={28}, number={11}, note={Gesehen am 12.04.2018}, journal={Annals of oncology}, doi={10.1093/annonc/mdx500}, } @article{UBHD-69064194, author={Heilig, Christoph E. and L{\"o}ffler, Harald and Mahlknecht, Ulrich Rudolph and Janssen, Johannes W. G. and Ho, Anthony Dick and Jauch, Anna and Kr{\"a}mer, Alwin}, title={Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group}, year={2010}, pages={895-902}, language={eng}, issn={1582-4934}, volume={14}, number={4 vom: Apr.}, note={First published: 10 May 2010 ; Gesehen am 11.04.2023}, journal={Journal of cellular and molecular medicine}, doi={10.1111/j.1582-4934.2009.00905.x}, } @article{UBHD-68575790, author={Hemminki, Kari and Chen, Bowang and Kumar, Abhishek and Melander, Olle and Manjer, Jonas and Hallmans, G{\"o}ran and Pettersson-Kymmer, Ulrika and Ohlsson, Claes and Folprecht, Gunnar and L{\"o}ffler, Harald and Kr{\"a}mer, Alwin and F{\"o}rsti, Asta}, title={Germline genetics of cancer of unknown primary (CUP) and its specific subtypes}, year={2016}, pages={22140-22149}, language={eng}, issn={1949-2553}, volume={7}, number={16}, note={Gesehen am 12.05.2020}, journal={OncoTarget}, doi={10.18632/oncotarget.7903}, } @article{UBHD-68790983, author={Hensel, Manfred and Zoz, Martin and Giesecke, Christian and Benner, Axel and Neben, Kai and Jauch, Anna and Stilgenbauer, Stephan and Ho, Anthony Dick and Kr{\"a}mer, Alwin}, title={High rate of centrosome aberrations and correlation with proliferative activity in patients with untreated B-cell chronic lymphocytic leukemia}, year={2007}, pages={978-983}, language={eng}, issn={1097-0215}, volume={121}, number={5}, note={Gesehen am 18.10.2021}, journal={International journal of cancer}, doi={10.1002/ijc.22752}, } @article{UBHD-68864195, author={Homan, Claire C. and King-Smith, Sarah L. and Lawrence, David M. and Arts, Peer and Feng, Jinghua and Andrews, James and Armstrong, Mark and Ha, Thuong and Dobbins, Julia and Drazer, Michael W. and Yu, Kai and B{\"o}d{\"o}r, Csaba and Cantor, Alan and Cazzola, Mario and Degelman, Erin and DiNardo, Courtney D. and Duployez, Nicolas and Favier, Remi and Fr{\"o}hling, Stefan and Fitzgibbon, Jude and Klco, Jeffery M. and Kr{\"a}mer, Alwin and Kurokawa, Mineo and Lee, Joanne and Malcovati, Luca and Morgan, Neil V. and Natsoulis, Georges and Owen, Carolyn and Patel, Keyur P. and Preudhomme, Claude and Raslova, Hana and Rienhoff, Hugh and Ripperger, Tim and Schulte, Rachael and Tawana, Kiran and Velloso, Elvira and Yan, Benedict and Liu, Paul and Godley, Lucy A. and Schreiber, Andreas W. and Hahn, Christopher N. and Scott, Hamish S. and Brown, Anna L.}, title={The RUNX1 database (RUNX1db)}, subtitle={establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy}, year={2021}, pages={3004-3007}, language={eng}, issn={1592-8721}, volume={106}, number={11}, note={Gesehen am 11.01.2022}, journal={Haematologica}, doi={10.3324/haematol.2021.278762}, } @article{UBHD-69151401, author={Homan, Claire C. and Drazer, Michael W. and Yu, Kai and Lawrence, David M. and Feng, Jinghua and Arriola-Martinez, Luis and Pozsgai, Matthew J. and McNeely, Kelsey E. and Ha, Thuong and Venugopal, Parvathy and Arts, Peer and King-Smith, Sarah L. and Cheah, Jesse and Armstrong, Mark and Wang, Paul and B{\"o}d{\"o}r, Csaba and Cantor, Alan B. and Cazzola, Mario and Degelman, Erin and DiNardo, Courtney D. and Duployez, Nicolas and Favier, Remi and Fr{\"o}hling, Stefan and Rio-Machin, Ana and Klco, Jeffery M. and Kr{\"a}mer, Alwin and Kurokawa, Mineo and Lee, Joanne and Malcovati, Luca and Morgan, Neil V. and Natsoulis, Georges and Owen, Carolyn and Patel, Keyur P. and Preudhomme, Claude and Raslova, Hana and Rienhoff, Hugh and Ripperger, Tim and Schulte, Rachael and Tawana, Kiran and Velloso, Elvira and Yan, Benedict and Kim, Erika and Sood, Raman and Hsu, Amy P. and Holland, Steven M. and Phillips, Kerry and Poplawski, Nicola K. and Babic, Milena and Wei, Andrew H. and Forsyth, Cecily and Mar Fan, Helen and Lewis, Ian D. and Cooney, Julian and Susman, Rachel and Fox, Lucy C. and Blombery, Piers and Singhal, Deepak and Hiwase, Devendra and Phipson, Belinda and Schreiber, Andreas W. and Hahn, Christopher N. and Scott, Hamish S. and Liu, Paul and Godley, Lucy A. and Brown, Anna L.}, title={Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41}, year={2023}, pages={6092-6107}, language={eng}, issn={2473-9537}, volume={7}, number={20 vom: Okt.}, note={Gesehen am 11.12.2023}, journal={Blood advances}, doi={10.1182/bloodadvances.2023010045}, } @article{UBHD-68866497, author={Hose, Dirk and Rème, Thierry and Meißner, Tobias and Moreaux, Jérôme and Seckinger, Anja and Lewis, Joe and Benes, Vladimir and Benner, Axel and Hundemer, Michael and Hielscher, Thomas and Shaughnessy, John D., Jr and Barlogie, Bart and Neben, Kai and Kr{\"a}mer, Alwin and Hillengaß, Jens and Bertsch, Uta and Jauch, Anna and De Vos, John and Rossi, Jean-François and M{\"o}hler, Thomas and Blake, Jonathon and Zimmermann, J{\"u}rgen and Klein, Bernard and Goldschmidt, Hartmut}, title={Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma}, year={2009}, pages={4331-4340}, language={eng}, issn={1528-0020}, volume={113}, number={18}, note={Prepublished online as Blood first edition paper, January 26, 2009 ; Gesehen am 14.01.2022}, journal={Blood}, doi={10.1182/blood-2008-09-178350}, } @article{UBHD-67891250, author={Kaaks, Rudolf and Kr{\"a}mer, Alwin}, title={Risk factors for cancers of unknown primary site}, subtitle={results from the prospective EPIC cohort}, year={2014}, pages={2475-2481}, language={eng}, issn={1097-0215}, volume={135}, number={10}, note={Gesehen am 23.10.2015}, journal={International journal of cancer}, doi={10.1002/ijc.28874}, } @article{UBHD-68921324, author={K{\"a}fer, Gabriele and Willer, Andreas and Ludwig, Wolf-Dieter and Kr{\"a}mer, Alwin and Hehlmann, R{\"u}diger and Hastka, Jan}, title={Intracellular expression of CD61 precedes surface expression}, year={1999}, pages={472-474}, language={eng}, issn={1432-0584}, volume={78}, number={10}, note={Gesehen am 23.05.2022}, journal={Annals of hematology}, doi={10.1007/s002770050601}, } @article{UBHD-68264860, author={Karakaya, Kadin and Herbst, Friederike and Ball, Claudia R. and Glimm, Hanno and Kr{\"a}mer, Alwin and L{\"o}ffler, Harald}, title={Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase}, year={2012}, pages={3492-3503}, language={eng}, issn={1551-4005}, volume={11}, number={18}, note={Im Titel ist 0/1 tiefgestellt ; Published online: 16 Aug 2012 ; Gesehen am 25.06.2018}, journal={Cell cycle}, doi={10.4161/cc.21801}, } @article{UBHD-68463215, author={Kayser, Sabine and Kr{\"a}mer, Alwin and Ho, Anthony Dick and M{\"u}ller-Tidow, Carsten and Schlenk, Richard Friedrich}, title={Allogeneic hematopoietic cell transplantation improves outcome of adults with t(6;9) acute myeloid leukemia - results from an international collaborative study}, year={2020}, pages={161-169$t9}, language={eng}, issn={1592-8721}, volume={105}, number={1}, note={Pre-published: April 19, 2019 ; Gesehen am 27.01.2020}, journal={Haematologica}, doi={10.3324/haematol.2018.208678}, url={https://doi.org/10.3324/haematol.2018.208678}, library={UB}, } @article{UBHD-68290169, author={Kayser, Sabine and Benner, Axel and Kr{\"a}mer, Alwin and Ho, Anthony Dick and Schlenk, Richard Friedrich}, title={Characteristics and outcome of patients with therapy-related acute promyelocytic leukemia front-line treated with or without arsenic trioxide}, year={2017}, pages={2347-2354}, language={eng}, issn={1476-5551}, volume={31}, number={11}, note={Gesehen am 30.07.2018}, journal={Leukemia}, doi={10.1038/leu.2017.92}, } @article{UBHD-68895256, author={Kayser, Sabine and Schlenk, Richard Friedrich and Kr{\"a}mer, Alwin and M{\"u}ller-Tidow, Carsten and Bornh{\"a}user, Martin}, title={Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide}, subtitle={an international collaborative study}, year={2021}, pages={3100-3106}, language={eng}, issn={1592-8721}, volume={106}, number={12}, note={Gesehen am 16.03.2022}, journal={Haematologica}, doi={10.3324/haematol.2021.278722}, } @article{UBHD-68290172, author={Kayser, Sabine and Benner, Axel and M{\"u}ller-Tidow, Carsten and Ho, Anthony Dick and Schlenk, Richard Friedrich and Kr{\"a}mer, Alwin}, title={Clinical impact of KMT2C and SPRY4 expression levels in intensively treated younger adult acute myeloid leukemia patients}, year={2017}, pages={544-552}, language={eng}, issn={1600-0609}, volume={99}, number={6}, note={Gesehen am 30.07.2018}, journal={European journal of haematology}, doi={10.1111/ejh.12972}, } @article{UBHD-68356926, author={Kayser, Sabine and Stadtherr, Peter and Uppenkamp, Michael and Bochtler, Tilmann and Hegenbart, Ute and Ho, Anthony Dick and Dreger, Peter and Kr{\"a}mer, Alwin}, title={Pretransplant NPM1 MRD levels predict outcome after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia}, year={2016}, pages={7 S.}, language={eng}, issn={2044-5385}, volume={6(2016) Artikel-Nummer e449}, number={7 Seiten}, note={Gesehen am 11.02.2019 ; Im Titel ist "NPM1" kursiv geschrieben}, journal={Blood cancer journal}, doi={10.1038/bcj.2016.46}, } @article{UBHD-68440744, author={Kirchner, Martina and Neumann, Olaf and Volckmar, Anna-Lena and St{\"o}gbauer, Fabian and Allg{\"a}uer, Michael and Kazdal, Daniel and Budczies, Jan and Rempel, Eugen and Brandt, Regine and Talla, Suranand Babu and Winterfeld, Moritz von and Leichsenring, Jonas and Bochtler, Tilmann and Kr{\"a}mer, Alwin and Springfeld, Christoph and Schirmacher, Peter and Penzel, Roland and Endris, Volker and Stenzinger, Albrecht}, title={RNA-based detection of gene fusions in formalin-fixed and paraffin-embedded solid cancer samples}, year={2019}, pages={17 S.}, language={eng}, issn={2072-6694}, volume={11(2019}, note={Gesehen am 15.10.2019}, journal={Cancers}, doi={10.3390/cancers11091309}, url={https://doi.org/10.3390/cancers11091309}, library={UB}, } @article{UBHD-69147184, author={K{\"o}hrer, Sebastian and Dittrich, Tobias and Schorb, Martin and Weinhold, Niels and Haberbosch, Isabella and B{\"o}rmel, Mandy and Pajor, Gabor and Goldschmidt, Hartmut and M{\"u}ller-Tidow, Carsten and Raab, Marc-Steffen and John, Lukas and Seckinger, Anja and Brobeil, Alexander and Dreger, Peter and Tornóczky, Tamás and Pajor, László and Hegenbart, Ute and Sch{\"o}nland, Stefan and Schwab, Yannick and Kr{\"a}mer, Alwin}, title={High-throughput electron tomography identifies centriole over-elongation as an early event in plasma cell disorders}, year={2023}, pages={2468-2478}, language={eng}, issn={1476-5551}, volume={37}, number={12}, note={Online ver{\"o}ffentlicht: 11. Oktober 2023 ; Gesehen am 28.11.2023}, journal={Leukemia}, doi={10.1038/s41375-023-02056-y}, } @article{UBHD-68394019, author={Konotop, Gleb and Bausch, Elena and Boutros, Michael and Kr{\"a}mer, Alwin and Raab, Marc-Steffen}, title={Pharmacological inhibition of centrosome clustering by slingshot-mediated cofilin activation and actin cortex destabilization}, year={2016}, pages={6690-6700}, language={eng}, issn={1538-7445}, volume={76}, number={22}, note={Gesehen am 29.05.2019}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-16-1144}, } @article{UBHD-68822957, author={Kornacker, Martin and Kr{\"a}mer, Alwin and Leo, Eugen and Ho, Anthony Dick}, title={Occurrence of sarcoidosis subsequent to chemotherapy for non-Hodgkin's lymphoma}, subtitle={report of two cases}, year={2002}, pages={103-105}, language={eng}, issn={1432-0584}, volume={81}, number={2}, note={Gesehen am 14.12.2021}, journal={Annals of hematology}, doi={10.1007/s00277-001-0415-6}, } @article{UBHD-68871857, author={Kr{\"a}mer, Alwin and H{\"o}rner, Susanne and Willer, Andreas and Fr{\"u}hauf, Stefan and Hochhaus, Andreas and Hallek, Michael and Hehlmann, R{\"u}diger}, title={Adhesion to fibronectin stimulates proliferation of wild-type and bcr/abl-transfected murine hematopoietic cells}, year={1999}, pages={2087-2092}, language={eng}, issn={1091-6490}, volume={96}, number={5 vom: M{\"a}rz}, note={Gesehen am 28.01.2022}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.96.5.2087}, } @incollection{UBHD-68495220, author={Kr{\"a}mer, Alwin}, title={Akute myeloische Leuk{\"a}mie}, year={2020}, pages={96-106}, language={ger}, isbn={978-3-11-059979-4 and 978-3-11-059855-1}, booktitle={Myeloische Neoplasien}, } @article{UBHD-68822942, author={Kr{\"a}mer, Alwin and Schultheis, Beate and Bergmann, J. and Willer, Andreas and Hegenbart, Ute and Ho, Anthony Dick and Goldschmidt, Hartmut and Hehlmann, R{\"u}diger}, title={Alterations of the cyclin D1/pRb/p16INK4A pathway in multiple myeloma}, year={2002}, pages={1844-1851}, language={eng}, issn={1476-5551}, volume={16}, number={9}, note={Gesehen am 14.12.2021 ; INK4A im Titel ist hochgestellt}, journal={Leukemia}, doi={10.1038/sj.leu.2402609}, } @article{UBHD-69085802, author={Kr{\"a}mer, Alwin and Bochtler, Tilmann and Pauli, Chantal and Baciarello, Giulia and Delorme, Stefan and Hemminki, Kari and Mileshkin, Linda and Patrikidou, Anna and Moch, Holger and Oien, Karin and Olivier, Timothée and Wasan, Harpreet and Zarkavelis, George and Pentheroudakis, George and Fizazi, Karim}, title={Cancer of unknown primary}, subtitle={ESMO clinical practice guideline for diagnosis, treatment and follow-up}, year={2023}, pages={228-246}, language={eng}, issn={1569-8041}, volume={34}, number={3 vom: M{\"a}rz}, note={Online ver{\"o}ffentlicht am 20. Dezember 2022, Artikelversion vom 20. Februar 2023 ; Gesehen am 15.12.2023}, journal={Annals of oncology}, doi={10.1016/j.annonc.2022.11.013}, } @article{UBHD-68822948, author={Kr{\"a}mer, Alwin and Neben, Kai and Ho, Anthony Dick}, title={Centrosome replication, genomic instability and cancer}, year={2002}, pages={767-775}, language={eng}, issn={1476-5551}, volume={16}, number={5}, note={Gesehen am 14.12.2021}, journal={Leukemia}, doi={10.1038/sj.leu.2402454}, } @article{UBHD-68807879, author={Kr{\"a}mer, Alwin and Schweizer, Silja and Neben, Kai and Giesecke, Christian and Kalla, J. and Katzenberger, T. and Benner, Axel and M{\"u}ller-Hermelink, H. K. and Ho, Anthony Dick and Ott, G.}, title={Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma}, year={2003}, pages={2207-2213}, language={eng}, issn={1476-5551}, volume={17}, number={11}, note={Gesehen am 03.12.2021}, journal={Leukemia}, doi={10.1038/sj.leu.2403142}, } @article{UBHD-68939273, author={Kr{\"a}mer, Alwin and Maier, Bettina and Bartek, Jiri}, title={Centrosome clustering and chromosomal (in)stability}, subtitle={A matter of life and death}, year={2011}, pages={324-335}, language={eng}, issn={1878-0261}, volume={5}, number={4}, note={Gesehen am 08.07.2022}, journal={Molecular oncology}, doi={10.1016/j.molonc.2011.05.003}, } @incollection{UBHD-68446643, author={Kr{\"a}mer, Alwin and Bochtler, Tilmann}, title={Enasidenib}, year={2018}, pages={187-197}, language={eng}, isbn={978-3-319-91439-8}, note={Gesehen am 28.10.2019}, booktitle={Small molecules in hematology}, editor={Martens, Uwe Marc}, doi={10.1007/978-3-319-91439-8_9}, } @article{UBHD-68325826, author={Kr{\"a}mer, Alwin and Heuser, Michael}, title={IDH-Inhibitoren}, year={2017}, pages={632-638}, language={ger}, issn={1433-0415}, volume={23}, number={8}, note={Paralleltitel von Frontdoor {\"u}bernommen ; Gesehen am 07.11.2018}, journal={Der Onkologe}, doi={10.1007/s00761-017-0220-z}, } @article{UBHD-68793285, author={Kr{\"a}mer, Alwin and Reiter, Andreas and Kruth, Jens and Erben, Philipp and Hochhaus, Andreas and M{\"u}ller, Martin Christian and Cross, Nicholas C. P. and Jones, Amy V. and Ho, Anthony Dick and Hensel, Manfred}, title={JAK2-V617F mutation in a patient with Philadelphia-chromosome-positive chronic myeloid leukaemia}, year={2007}, pages={658-660}, language={eng}, issn={1474-5488}, volume={8}, number={7}, note={Gesehen am 25.10.2021}, journal={The lancet}, doi={10.1016/S1470-2045(07)70206-1}, } @incollection{UBHD-69010300, author={Kr{\"a}mer, Alwin}, title={Metastasen bei unbekanntem Prim{\"a}rtumor (CUP: Carcinoma of Unknown Primary)}, year={2010}, pages={151-156}, language={ger}, isbn={978-3-00-032813-8}, booktitle={Therapiealgorithmen Onkologie}, editor={Batran, Salah-Eddin al-}, } @article{UBHD-69294892, author={Kr{\"a}mer, Alwin and Bochtler, Tilmann and Pauli, Chantal and Shiu, Kai-Keen and Cook, Natalie and Menezes, Juliana Janoski de and Pazo-Cid, Roberto A. and Losa, Ferran and Robbrecht, Debbie GJ and Tomášek, Jiří and Arslan, Cagatay and {\"O}zg{\"u}roğlu, Mustafa and Stahl, Michael and Bigot, Frédéric and Kim, Sun Young and Naito, Yoichi and Italiano, Antoine and Chalabi, Nasséra and Durán-Pacheco, Gonzalo and Michaud, Chantal and Scarato, Jeremy and Thomas, Marlene and Ross, Jeffrey S. and Moch, Holger and Mileshkin, Linda}, title={Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO)}, subtitle={an open-label, randomised, phase 2 study}, year={2024}, pages={527-539}, language={eng}, issn={1474-547X}, volume={404}, number={10452}, note={Gesehen am 28.01.2025}, journal={The lancet}, doi={10.1016/S0140-6736(24)00814-6}, } @article{UBHD-69117781, author={Kr{\"a}mer, Alwin and Thiede, Christian}, title={Pathogenese und molekulare Diagnostik der akuten myeloischen Leuk{\"a}mie}, year={2022}, pages={463-473}, language={ger}, issn={2731-7234}, volume={28}, number={6}, note={Ver{\"o}ffentlicht: 27 April 2022 ; Gesehen am 31.08.2023}, journal={Die Onkologie}, doi={10.1007/s00761-022-01183-y}, } @article{UBHD-69055021, author={Kr{\"a}mer, Alwin}, title={PML promotes senescence via JAK/STAT signaling}, subtitle={comment on: Hubackova S, et al. Cell Cycle 2010; 9:3085-99}, year={2010}, pages={2931}, language={eng}, issn={1551-4005}, volume={9}, number={15}, note={Das PDF enth{\"a}lt mehrere Kommentare verschiedener Verfasser ; Die zitierten und zu zitierenden Seitenzahlen stimmen nicht mit den ver{\"o}ffentlichten Seitenzahlen {\"u}berein ; Gesehen am 23.03.2023}, journal={Cell cycle}, doi={10.4161/cc.9.15.12697}, } @article{UBHD-68920072, author={Kr{\"a}mer, Alwin and L{\"o}ffler, Harald and Bergmann, J{\"o}rg Stefan and Hochhaus, Andreas and Hehlmann, R{\"u}diger}, title={Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia}, year={2001}, pages={62-68}, language={eng}, issn={1476-5551}, volume={15}, number={1}, note={Gesehen am 18.05.2022}, journal={Leukemia}, doi={10.1038/sj.leu.2402005}, } @article{UBHD-68395550, author={Kr{\"a}mer, Alwin and Ho, Anthony Dick}, title={Stammzellentherapie}, subtitle={Frischzellentherapie der Zukunft?}, year={2007}, pages={173-188}, language={ger}, issn={0073-1641}, volume={50}, journal={Heidelberger Jahrb{\"u}cher}, editor={Laufs, Adolf}, } @article{UBHD-66907971, author={Kr{\"a}mer, Alwin and Ho, Anthony Dick}, title={Stammzellentherapie - Frischzellentherapie der Zukunft}, year={2007}, pages={173-188}, language={ger}, issn={2509-2464}, volume={50.2006}, journal={Heidelberger Jahrb{\"u}cher}, url={http://digi.ub.uni-heidelberg.de/diglit/hdjb2006/181}, library={UB}, } @book{UBHD-65258076, author={Kr{\"a}mer, Alwin}, title={St{\"o}rungen der Zellzyklusregulation bei h{\"a}matologischen Neoplasien}, year={2000}, pages={Getr. Z{\"a}hlung}, language={ger}, note={Enth. als weiteren Bestandteil 17 Sonderdrucke in Zusammenarb. mit anderen Verf. - Nicht f. d. Austausch}, school={Heidelberg, Univ., Habil.-Schr., 2000}, library={UB [Signatur: 2001 U 212] ; UW [Signatur: Habil. 01.3]}, } @article{UBHD-68404484, author={Kraft, Bianca and Kirsch, Michael and Wuchter, Patrick and Bugert, Peter and Hielscher, Thomas and Blank, Norbert and Kr{\"a}mer, Alwin}, title={SMC3 protein levels impact on karyotype and outcome in acute myeloid leukemia}, year={2019}, pages={795-799}, language={eng}, issn={1476-5551}, volume={33}, number={3}, note={Published: 15 October 2018 ; Gesehen am 04.07.2019}, journal={Leukemia}, doi={10.1038/s41375-018-0287-6}, } @article{UBHD-68447565, author={Kriegsmann, Katharina and L{\"o}ffler, Harald and Eckstein, Volker and Schulz, Renate and Kr{\"a}ker, Sandra and Braun, Ute and Luft, Thomas and Hegenbart, Ute and Sch{\"o}nland, Stefan and Dreger, Peter and Kr{\"a}mer, Alwin and Ho, Anthony Dick and M{\"u}ller-Tidow, Carsten and Hundemer, Michael}, title={CD7 is expressed on a subset of normal CD34-positive myeloid precursors}, year={2018}, pages={318-325}, language={eng}, issn={1600-0609}, volume={101}, number={3}, note={Gesehen am 29.10.2019}, journal={European journal of haematology}, doi={10.1111/ejh.13100}, } @article{UBHD-68986163, author={Kunadt, Désirée and Kr{\"a}mer, Alwin and M{\"u}ller-Tidow, Carsten and Bornh{\"a}user, Martin}, title={Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation}, year={2022}, pages={1-15}, language={eng}, issn={1756-8722}, volume={15(2022) vom: Sept.}, number={Artikel-ID 126}, note={Gesehen am 16.11.2022}, journal={Journal of hematology & oncology}, doi={10.1186/s13045-022-01339-8}, } @article{UBHD-69050398, author={Leber, Blanka and Maier, Bettina and Fuchs, Florian and Chi, Jing and Riffel, Phillip and Anderhub, Simon and Wagner, Ludmila and Ho, Anthony Dick and Salisbury, Jeffrey L. and Boutros, Michael and Kr{\"a}mer, Alwin}, title={Proteins required for centrosome clustering in cancer cells}, year={2010}, pages={1-11}, language={eng}, issn={1946-6242}, volume={2}, note={Gesehen am 10.03.2023}, journal={Science translational medicine}, doi={10.1126/scitranslmed.3000915}, } @article{UBHD-68811287, author={Leo, Eugen and Kr{\"a}mer, Alwin and Hochhaus, Andreas and Krasniqi, Fatime and Hehlmann, R{\"u}diger and Ho, Anthony Dick}, title={Gangrene of the toes in a patient with chronic myelogenous leukemia after long-term hydroxyurea therapy}, year={2002}, pages={467-469}, language={eng}, issn={1432-0584}, volume={81}, number={8}, note={Gesehen am 10.12.2021}, journal={Annals of hematology}, doi={10.1007/s00277-002-0505-0}, } @article{UBHD-68754441, author={Leo, Eugen and Scheuer, Lars and Schmidt-Wolf, Ingo G. H. and Kerowgan, Mohammed and Schmitt, Christina and Leo, Albrecht and Baumbach, Tanja and Kr{\"a}mer, Alwin and Mey, Ulrich and Benner, Axel and Parwaresch, Reza and Ho, Anthony Dick}, title={Significant thrombocytopenia associated with the addition of rituximab to a combination of fludarabine and cyclophosphamide in the treatment of relapsed follicular lymphoma}, year={2004}, pages={251-257}, language={eng}, issn={1600-0609}, volume={73}, number={4}, note={Gesehen am 30.06.2021}, journal={European journal of haematology}, doi={10.1111/j.1600-0609.2004.00293.x}, } @article{UBHD-69292890, author={Lepp{\"a}, Aino-Maija and Grimes, Karen and Jeong, Hyobin and Huang, Frank Y. and Andrades, Alvaro and Waclawiczek, Alexander and Boch, Tobias and Jauch, Anna and Renders, Simon and Stelmach, Patrick and M{\"u}ller-Tidow, Carsten and Karpova, Darja and Sohn, Markus and Gr{\"u}nschl{\"a}ger, Florian and Hasenfeld, Patrick and Benito Garagorri, Eva and Thiel, Vera and Dolnik, Anna and Rodriguez-Martin, Bernardo and Bullinger, Lars and Mrózek, Krzysztof and Eisfeld, Ann-Kathrin and Kr{\"a}mer, Alwin and Sanders, Ashley D. and Korbel, Jan Oliver and Trumpp, Andreas}, title={Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype}, year={2024}, pages={39 S.}, language={eng}, issn={1546-1718}, volume={56}, note={Gesehen am 21.01.2025}, journal={Nature genetics}, doi={10.1038/s41588-024-01999-x}, } @article{UBHD-69166402, author={Le Tourneau, Christophe and André, Fabrice and Helland, Åslaug and Mileshkin, Linda and Minnaard, Warnyta and Schiel, Anja and Taskén, Kjetil and Thomas, David M. and Veronese, Maria Luisa and Durán-Pacheco, Gonzalo and Leyens, Lada and Rufibach, Kaspar and Thomas, Marlene and Kr{\"a}mer, Alwin}, title={Modified study designs to expand treatment options in personalised oncology}, subtitle={a multistakeholder view}, year={2023}, pages={1-15}, language={eng}, issn={1879-0852}, volume={194(2023) vom: Nov.}, number={Artikel-ID 113278}, note={Online verf{\"u}gbar 4 August 2023, Version des Artikels 10 October 2023 ; Gesehen am 29.01.2024}, journal={European journal of cancer}, doi={10.1016/j.ejca.2023.113278}, } @article{UBHD-68965770, author={L{\"o}ffler, Harald and Fechter, Anne and Matuszewska, Marc and Saffrich, Rainer and Mistrik, Martin and Marhold, Joachim and Hornung, Christin and Westermann, Frank and Bartek, Jiri and Kr{\"a}mer, Alwin}, title={Cep63 recruits Cdk1 to the centrosome}, subtitle={implications for regulation of mitotic entry, centrosome amplification, and genome maintenance}, year={2011}, pages={2129-2139}, language={eng}, issn={1538-7445}, volume={71}, number={6}, note={Gesehen am 20.09.2022}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-10-2684}, } @article{UBHD-67821444, author={L{\"o}ffler, Harald and Neben, Kai and Kr{\"a}mer, Alwin}, title={CUP-Syndrom}, subtitle={Epidemiologie und Pathogenese}, year={2014}, pages={107-111}, language={ger}, issn={1432-2102}, volume={54}, number={2}, note={Gesehen am 22.05.2015}, journal={Der Radiologe}, doi={10.1007/s00117-013-2544-z}, } @article{UBHD-68315881, author={L{\"o}ffler, Harald and Fechter, Anne and Liu, Fang and Kr{\"a}mer, Alwin}, title={DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites}, year={2013}, pages={2963-2972}, language={eng}, issn={1476-5594}, volume={32}, number={24}, note={Gesehen am 16.10.2018}, journal={Oncogene}, doi={10.1038/onc.2012.310}, } @article{UBHD-68791956, author={L{\"o}ffler, Harald and Bochtler, Tilmann and Tews, Britta and Tews, Bj{\"o}rn and Ho, Anthony Dick and Lukas, Jiri and Bartek, Jiri and Kr{\"a}mer, Alwin}, title={DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function}, year={2007}, pages={2541-2548}, language={eng}, issn={1551-4005}, volume={6}, number={20}, note={Gesehen am 20.10.2021}, journal={Cell cycle}, doi={10.4161/cc.6.20.4810}, } @article{UBHD-68347165, author={L{\"o}ffler, Harald and Pfarr, Nicole and Kriegsmann, Mark and Endris, Volker and Stenzinger, Albrecht and Weichert, Wilko and Kr{\"a}mer, Alwin}, title={Molecular driver alterations and their clinical relevance in cancer of unknown primary site}, year={2016}, pages={44322-44329}, language={eng}, issn={1949-2553}, volume={7}, number={28}, note={Gesehen am 14.01.2019}, journal={OncoTarget}, doi={10.18632/oncotarget.10035}, } @article{UBHD-67963640, author={L{\"o}ffler, Harald and Puthenparambil, Joe and Neben, Kai and Kr{\"a}mer, Alwin}, title={Patients with cancer of unknown primary}, subtitle={a retrospective analysis of 223 patients with adeno carcinoma or undifferentiated carcinoma}, year={2014}, pages={481-487}, language={eng}, issn={1866-0452}, volume={111}, number={27-28}, note={Gesehen am 05.04.2016}, journal={Deutsches {\"A}rzteblatt international}, doi={10.3238/arztebl.2014.0481}, } @article{UBHD-68238481, author={L{\"o}ffler, Harald and Kr{\"a}mer, Alwin}, title={Prognostisch g{\"u}nstige Subgruppen bei Krebs mit unklarem Primarius}, year={2017}, pages={993-999}, language={ger}, issn={1433-0415}, volume={23}, number={12}, note={Gesehen am 03.04.2018}, journal={Der Onkologe}, doi={10.1007/s00761-017-0241-7}, } @article{UBHD-68920061, author={L{\"o}ffler, Harald and Bergmann, J{\"o}rg Stefan and Hochhaus, Andreas and Hehlmann, R{\"u}diger and Kr{\"a}mer, Alwin}, title={Reduced risk for chronic myelogenous leukemia in individuals with the cytochrome P-450 gene polymorphism CYP1A1*2A}, year={2001}, pages={3874-3875}, language={eng}, issn={1528-0020}, volume={98}, number={13}, note={Gesehen am 18.05.2022}, journal={Blood}, doi={10.1182/blood.V98.13.3874}, } @article{UBHD-67820995, author={L{\"o}ffler, Harald and Neben, Kai and Kr{\"a}mer, Alwin}, title={Strukturierte Diagnostik und internistische Therapie des CUP-Syndroms}, year={2014}, pages={112-116}, language={ger}, issn={1432-2102}, volume={54}, number={2}, note={Gesehen am 21.05.2015}, journal={Der Radiologe}, doi={10.1007/s00117-013-2545-y}, } @article{UBHD-68325866, author={McClanahan, Fabienne and Hielscher, Thomas and Neben, Kai and Hillengaß, Jens and Kr{\"a}mer, Alwin and Ho, Anthony Dick and Witzens-Harig, Mathias}, title={Final results of a randomized trial comparing 1, 3, or 6 infusions of Rituximab plus 6 cycles CHOP provide valuable preliminary data towards a more cost-effective and safer treatment of advanced follicular lymphoma}, year={2012}, pages={E68-E71}, language={eng}, issn={1096-8652}, volume={87}, number={10}, note={Gesehen am 07.11.2018}, journal={American journal of hematology}, doi={10.1002/ajh.23286}, } @article{UBHD-68169336, author={Menon, Roopika and Bochtler, Tilmann and L{\"o}ffler, Harald and Kr{\"a}mer, Alwin}, title={Identification of therapeutically targetable genomic alterations in a cohort of patients with CUP using a hybrid-capture based next generation sequencing assay}, year={2016}, pages={S55-S55}, language={eng}, issn={1879-0852}, volume={69}, number={69(2016) Supplement 1}, note={Gesehen am 26.09.2017}, journal={European journal of cancer}, doi={10.1016/S0959-8049(16)32751-4}, } @article{UBHD-68947357, author={Middeke, Jan Moritz and Metzeler, Klaus H. and R{\"o}llig, Christoph and Kr{\"a}mer, Michael and Eckardt, Jan-Niklas and Stasik, Sebastian and Greif, Philipp* and Spiekermann, Karsten and RothenbergThurley, Maja and Krug, Utz and Braess, Jan and Kr{\"a}mer, Alwin and Hochhaus, Andreas and Br{\"u}mmendorf, Tim Henrik and Naumann, Ralph and Steffen, Bj{\"o}rn and Einsele, Hermann and Schaich, Markus and Burchert, Andreas and Neubauer, Andreas and G{\"o}rlich, Dennis and Sauerland, Cristina and Sch{\"a}ferEckart, Kerstin and Schliemann, Christoph and Krause, Stefan W. and H{\"a}nel, Mathias and Frickhofen, Norbert and Noppeney, Richard and Kaiser, Ulrich and Kaufmann, Martin and Kunadt, Désirée and W{\"o}rmann, Bernhard and Sockel, Katja and Bonin, Malte von and Herold, Tobias and M{\"u}ller-Tidow, Carsten and Platzbecker, Uwe and Berdel, Wolfgang E. and Serve, Hubert and Baldus, Claudia D. and Ehninger, Gerhard and Schetelig, Johannes and Hiddemann, Wolfgang and Bornh{\"a}user, Martin and St{\"o}lzel, Friedrich and Thiede, Christian}, title={Differential impact of IDH1/2 mutational subclasses on outcome in adult AML}, subtitle={results from a large multicenter study}, year={2022}, pages={1394-1405}, language={eng}, issn={2473-9537}, volume={6}, number={5}, note={Gesehen am 27.07.2022}, journal={Blood advances}, doi={10.1182/bloodadvances.2021004934}, } @article{UBHD-68957276, author={Mileshkin, Linda and Bochtler, Tilmann and Gatta, Gemma and Kurzrock, Razelle and Beringer, Andreas and M{\"u}ller-Ohldach, Mathis and Surinach, Andy and Perret, Camille and Thomas, Marlene and Gondos, Ádám and Kr{\"a}mer, Alwin}, title={Cancer-of-unknown-primary-origin}, subtitle={a SEER-medicare study of patterns of care and outcomes among elderly patients in clinical practice}, year={2022}, pages={1-14}, language={eng}, issn={2072-6694}, volume={14}, note={Gesehen am 25.08.2022}, journal={Cancers}, doi={10.3390/cancers14122905}, } @article{UBHD-69345225, author={M{\"o}hle, Robert and Pf{\"o}rsich, Margit and Fr{\"u}hauf, Stefan and Witt, Barbara and Kr{\"a}mer, Alwin and Haas, Rainer}, title={Filgrastim post-chemotherapy mobilizes more CD34+ cells with a different antigenic profile compared with use during steady-state hematopoiesis}, year={1994}, pages={827-832}, language={eng}, issn={0268-3369 and 0951-3078}, volume={14}, number={5}, journal={Bone marrow transplantation}, } @article{UBHD-69294878, author={Mosele, Fernanda and Westphalen, C. B. and Stenzinger, Albrecht and Barlesi, F. and Bayle, A. and Bièche, I. and Bonastre, J. and Castro, E. and Dienstmann, R. and Kr{\"a}mer, Alwin and Czarnecka, A. M. and Meric-Bernstam, F. and Michiels, S. and Miller, R. and Normanno, N. and Reis-Filho, J. and Remon, J. and Robson, M. and Rouleau, E. and Scarpa, A. and Serrano, C. and Mateo, J. and André, F.}, title={Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024}, subtitle={a report from the ESMO Precision Medicine Working Group}, year={2024}, pages={588-606}, language={eng}, issn={1569-8041}, volume={35}, number={7}, note={Online verf{\"u}gbar: 27. Mai 2024, Artikelversion: 21. Juni 2024 ; Gesehen am 28.01.2025}, journal={Annals of oncology}, doi={10.1016/j.annonc.2024.04.005}, } @article{UBHD-69354470, author={Moussa, Amira-Talaat and Cosenza, Marco R. and Wohlfromm, Timothy and Brobeil, Katharina and Hill, Anthony and Patrizi, Annarita and M{\"u}ller-Decker, Karin and Holland-Letz, Tim and Jauch, Anna and Kraft, Bianca and Kr{\"a}mer, Alwin}, title={STIL overexpression shortens lifespan and reduces tumor formation in mice}, year={2024}, pages={1-28}, language={eng}, issn={1553-7404}, volume={20}, note={Gesehen am 06.06.2025}, journal={PLoS Genetics}, doi={10.1371/journal.pgen.1011460}, } @article{UBHD-68755771, author={M{\"u}ller-Tidow, Carsten and Bug, Gesine and L{\"u}bbert, Michael and Kr{\"a}mer, Alwin and Krauter, J{\"u}rgen and Valent, Peter and Nachbaur, David and Berdel, Wolfgang E. and Ottmann, Oliver G. and Fritsch, Holger and Munzert, Gerd and Garin-Chesa, Pilar and Fleischer, Frank and Taube, Tillmann and D{\"o}hner, Hartmut}, title={A randomized, open-label, phase I/II trial to investigate the maximum tolerated dose of the Polo-like kinase inhibitor BI 2536 in elderly patients with refractory/relapsed acute myeloid leukaemia}, year={2013}, pages={214-222}, language={eng}, issn={1365-2141}, volume={163}, number={2}, journal={British journal of haematology}, doi={10.1111/bjh.12518}, } @article{UBHD-68811294, author={Neben, Kai and Giesecke, Christian and Schweizer, Silja and Ho, Anthony Dick and Kr{\"a}mer, Alwin}, title={Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile}, year={2003}, pages={289-291}, language={eng}, issn={1528-0020}, volume={101}, number={1 vom: Jan.}, note={Prepublished online as Blood first edition paper, June 28, 2002 ; Gesehen am 10.12.2021}, journal={Blood}, doi={10.1182/blood-2002-04-1188}, } @article{UBHD-68811297, author={Neben, Kai and M{\"o}hler, Thomas and Benner, Axel and Kr{\"a}mer, Alwin and Egerer, Gerlinde and Ho, Anthony Dick and Goldschmidt, Hartmut}, title={Dose-dependent effect of Thalidomide on overall survival in relapsed multiple myeloma}, year={2002}, pages={3377-3382}, language={eng}, issn={1557-3265}, volume={8}, number={11}, note={Gesehen am 10.12.2021}, journal={Clinical cancer research}, } @article{UBHD-68822959, author={Neben, Kai and M{\"o}hler, Thomas and Egerer, Gerlinde and Kr{\"a}mer, Alwin and Hillengaß, Jens and Benner, Axel and Ho, Anthony Dick and Goldschmidt, Hartmut}, title={High plasma basic fibroblast growth factor concentration is associated with response to Thalidomide in progressive multiple myeloma}, year={2001}, pages={2675-2681}, language={eng}, issn={1557-3265}, volume={7}, number={9}, note={Gesehen am 14.12.2021}, journal={Clinical cancer research}, } @article{UBHD-68822962, author={Neben, Kai and M{\"o}hler, Thomas and Kr{\"a}mer, Alwin and Benner, Axel and Egerer, Gerlinde and Ho, Anthony Dick and Goldschmidt, Hartmut}, title={Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion}, year={2001}, pages={605-608}, language={eng}, issn={1365-2141}, volume={115}, number={3}, note={Gesehen am 14.12.2021}, journal={British journal of haematology}, doi={10.1046/j.1365-2141.2001.03142.x}, } @article{UBHD-68811281, author={Neben, Kai and Mytilineos, Joannis and M{\"o}hler, Thomas and Preiss, Astrid and Kr{\"a}mer, Alwin and Ho, Anthony Dick and Opelz, Gerhard and Goldschmidt, Hartmut}, title={Polymorphisms of the tumor necrosis factor-α gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma}, year={2002}, pages={2263-2265}, language={eng}, issn={1528-0020}, volume={100}, number={6}, note={Gesehen am 10.12.2021}, journal={Blood}, doi={10.1182/blood.V100.6.2263}, } @article{UBHD-68795669, author={Neben, Kai and Ott, German and Schweizer, Silja and Kalla, J{\"o}rg and Tews, Bj{\"o}rn and Katzenberger, Tiemo and Hahn, Meinhard and Rosenwald, Andreas and Ho, Anthony Dick and M{\"u}ller-Hermelink, Hans Konrad and Lichter, Peter and Kr{\"a}mer, Alwin}, title={Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma}, year={2007}, pages={1669-1677}, language={eng}, issn={1097-0215}, volume={120}, number={8}, note={Gesehen am 02.11.2021}, journal={International journal of cancer}, doi={10.1002/ijc.22404}, } @article{UBHD-69124652, author={Neben, Kai and Tews, Bj{\"o}rn and Wrobel, Gunnar and Hahn, Meinhard and Kokocinski, Felix and Giesecke, Christian and Krause, Ulf and Ho, Anthony Dick and Kr{\"a}mer, Alwin and Lichter, Peter}, title={Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes}, year={2004}, pages={2379-2384}, language={eng}, issn={0950-9232}, volume={23}, number={13}, journal={Oncogene}, } @article{UBHD-69243538, author={Niederwieser, Dietger and Lang, Thomas and Krahl, Rainer and Heinicke, Thomas and Maschmeyer, Georg and Al-Ali, Haifa Kathrin and Schwind, Sebastian and Jentzsch, Barbara Madlen and Cross, Michael and Kahl, Christoph and Wolf, Hans-Heinrich and Sayer, Herbert and Schulze, Antje and Dreger, Peter and Hegenbart, Ute and Kr{\"a}mer, Alwin and Junghanß, Christian and M{\"u}gge, Lars-Olof and H{\"a}hling, Detlev and Hirt, Carsten and Sp{\"a}th, Christian and Peter, Norma and Opitz, Bernhard and Florsch{\"u}tz, Axel and Reifenrath, Kolja Franz Bogislaw and Zojer, Niklas and Scholl, Sebastian and P{\"o}nisch, Wolfram and Heyn, Simone and Vučinić, Vladan and Hochhaus, Andreas and Aul, Carlo and Giagounidis, Aristoteles and Balleisen, Leopold and Oldenkott, Bernd and Staib, Peter and Kiehl, Michael G. and Sch{\"u}tte, Wolfgang and Naumann, Ralph and Eimermacher, Hartmut and D{\"o}rken, Bernd and Sauerland, Cristina and Lengfelder, Eva and Hiddemann, Wolfgang and W{\"o}rmann, Bernhard and M{\"u}ller-Tidow, Carsten and Serve, Hubert and Schliemann, Christoph and Hehlmann, R{\"u}diger and Berdel, Wolfgang E. and Pfirrmann, Markus and Krug, Utz and Hoffmann, Verena Sophia}, title={Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years}, subtitle={a randomized German inter-group study}, year={2023}, pages={547-561}, language={eng}, issn={1432-0584}, volume={102}, number={3}, note={Online ver{\"o}ffentlicht: 25. Januar 2023}, journal={Annals of hematology}, doi={10.1007/s00277-023-05087-8}, } @article{UBHD-67842384, author={Niederwieser, Dietger and Hegenbart, Ute and Kr{\"a}mer, Alwin and Dreger, Peter}, title={Higher leukemia free survival after post-induction hematopoietic cell transplantation compared to consolidation therapy in patients > 60 years with acute myelogenous leukemia (AML)}, subtitle={report from the AML 2004 east german study group (OSHO)}, year={2014}, pages={1 S.}, language={eng}, issn={1528-0020}, volume={124(2014}, note={Gesehen am 07.07.2015}, journal={Blood}, } @article{UBHD-68394750, author={Ottmann, Oliver G. and Kr{\"a}mer, Alwin and Bochtler, Tilmann}, title={Phase I dose-escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia}, year={2019}, pages={1018-1021}, language={eng}, issn={1365-2141}, volume={184}, number={6}, note={First published: 08 June 2018 ; Gesehen am 03.06.2019}, journal={British journal of haematology}, doi={10.1111/bjh.15204}, } @article{UBHD-68647373, author={Petersen, Asger B. and Konotop, Gleb and Hanafiah, Nur Hafzan Md and Hammershøj, P. and Raab, Marc-Steffen and Kr{\"a}mer, Alwin and Clausen, M. H.}, title={Strategies for improving the solubility and metabolic stability of griseofulvin analogues}, year={2016}, pages={210-215}, language={eng}, issn={1768-3254}, volume={116}, note={Gesehen am 12.10.2020 ; Available online 28 March 2016}, journal={European journal of medicinal chemistry}, doi={10.1016/j.ejmech.2016.03.071}, } @article{UBHD-68293428, author={Petersen, Asger B. and Konotop, Gleb and Hanafiah, Nur Hafzan Md and Raab, Marc-Steffen and Kr{\"a}mer, Alwin}, title={Synthesis and formulation studies of griseofulvin analogues with improved solubility and metabolic stability}, year={2017}, pages={240-247}, language={eng}, issn={1768-3254}, volume={130}, note={Gesehen am 08.08.2018}, journal={European journal of medicinal chemistry}, doi={10.1016/j.ejmech.2017.02.055}, } @article{UBHD-67963649, author={Placke, Theresa and Kr{\"a}mer, Alwin and Fr{\"o}hling, Stefan}, title={Requirement for CDK6 in MLL-rearranged acute myeloid leukemia}, year={2014}, pages={496-503}, language={eng}, issn={1528-0020}, volume={124}, number={1}, note={Gesehen am 05.04.2016}, journal={Blood}, doi={10.1182/blood-2014-02-558114}, } @article{UBHD-68569743, author={Platzbecker, Uwe and Kr{\"a}mer, Alwin and Bochtler, Tilmann}, title={Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2)}, subtitle={an open-label, multicentre, phase 2 trial}, year={2018}, pages={1668-1679}, language={eng}, issn={1474-5488}, volume={19}, number={12}, note={Gesehen am 23.04.2020}, journal={The lancet}, doi={10.1016/S1470-2045(18)30580-1}, } @article{UBHD-69321415, author={Pouyiourou, Maria and Mokry, Theresa and Feszler, Maximilian and Teifke, Andrea and Kreft, Andreas and Kr{\"a}mer, Alwin}, title={Cancer of unknown primary derived from regressed breast cancer}, year={2024}, pages={1-3}, language={eng}, issn={1432-1335}, volume={150}, note={Gesehen am 24.03.2025}, journal={Journal of cancer research and clinical oncology}, doi={10.1007/s00432-024-05768-5}, } @article{UBHD-69222165, author={Pouyiourou, Maria and Bochtler, Tilmann and Coith, Cornelia and Wikman, Harriet and Kraft, Bianca and Hielscher, Thomas and Stenzinger, Albrecht and Riethdorf, Sabine and Pantel, Klaus and Kr{\"a}mer, Alwin}, title={Frequency and prognostic value of circulating tumor cells in cancer of unknown primary}, year={2024}, pages={297-306}, language={eng}, issn={1530-8561}, volume={70}, number={1 vom: Jan.}, note={Ver{\"o}ffentlicht: 4. Januar 2024 ; Gesehen am 10.06.2024}, journal={Clinical chemistry}, doi={10.1093/clinchem/hvad180}, } @article{UBHD-68800397, author={Pouyiourou, Maria and Wohlfromm, Timothy and Kraft, Bianca and Hielscher, Thomas and Stichel, Damian and Deimling, Andreas von and Delorme, Stefan and Endris, Volker and Neumann, Olaf and Stenzinger, Albrecht and Kr{\"a}mer, Alwin and Bochtler, Tilmann}, title={Local ablative treatment with surgery and/or radiotherapy in single-site and oligometastatic carcinoma of unknown primary}, year={2021}, pages={179-189}, language={eng}, issn={1879-0852}, volume={157(2021) vom: Nov.}, note={Gesehen am 11.11.2021}, journal={European journal of cancer}, doi={10.1016/j.ejca.2021.08.019}, } @article{UBHD-69216576, author={Pouyiourou, Maria and Kraft, Bianca and Wohlfromm, Timothy and Stahl, Michael and Kubuschok, Boris and L{\"o}ffler, Harald and Hacker, Ulrich T. and H{\"u}bner, Gerdt and Weiss, Lena and Bitzer, Michael and Ernst, Thomas and Sch{\"u}tt, Philipp and Hielscher, Thomas and Delorme, Stefan and Kirchner, Martina and Kazdal, Daniel and Ball, Markus and Kluck, Klaus and Stenzinger, Albrecht and Bochtler, Tilmann and Kr{\"a}mer, Alwin}, title={Nivolumab and ipilimumab in recurrent or refractory cancer of unknown primary}, subtitle={a phase II trial}, year={2023}, pages={1-21}, language={eng}, issn={2041-1723}, volume={14}, number={Artikel-ID 6761}, note={Gesehen am 17.05.2024}, journal={Nature Communications}, doi={10.1038/s41467-023-42400-5}, } @article{UBHD-68329818, author={Raab, Marc-Steffen and Breitkreutz, Iris and Podar, Klaus and Nissen, Felix and Mier, Walter and Haberkorn, Uwe and Ho, Anthony Dick and Goldschmidt, Hartmut and Kr{\"a}mer, Alwin}, title={GF-15, a novel inhibitor of centrosomal clustering, suppresses tumor cell growth in vitro and in vivo}, year={2012}, pages={5374-5385}, language={eng}, issn={1538-7445}, volume={72}, number={20}, note={Gesehen am 19.11.2018}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-12-2026}, } @article{UBHD-67955826, author={Radujković, Aleksandar and Dietrich, Sascha and Bochtler, Tilmann and Kr{\"a}mer, Alwin and Sch{\"o}ning, Tilman and Ho, Anthony Dick and Dreger, Peter and Luft, Thomas}, title={Azacitidine and low-dose cytarabine in palliative patients with acute myeloid leukemia and high bone marrow blast counts}, subtitle={a retrospective single-center experience}, year={2014}, pages={112-117}, language={eng}, issn={1600-0609}, volume={93}, number={2}, note={Gesehen am 15.03.2016}, journal={European journal of haematology}, doi={10.1111/ejh.12308}, } @article{UBHD-68605111, author={R{\"o}llig, Christoph and Serve, Hubert and H{\"u}ttmann, Andreas and Noppeney, Richard and M{\"u}ller-Tidow, Carsten and Krug, Utz and Baldus, Claudia D. and Brandts, Christian H. and Kunzmann, Volker and Einsele, Hermann and Kr{\"a}mer, Alwin and Sch{\"a}fer-Eckart, Kerstin and Neubauer, Andreas and Burchert, Andreas and Giagounidis, Aristoteles and Krause, Stefan W. and Mackensen, Andreas and Aulitzky, Walter and Herbst, Regina and H{\"a}nel, Mathias and Kiani, Alexander and Frickhofen, Norbert and Kullmer, Johannes and Kaiser, Ulrich and Link, Hartmut and Geer, Thomas and Reichle, Albert and Junghanß, Christian and Repp, Roland and Heits, Frank and D{\"u}rk, Heinz and Hase, Jana and Klut, Ina-Maria and Illmer, Thomas and Bornh{\"a}user, Martin and Schaich, Markus and Parmentier, Stefani and G{\"o}rner, Martin and Thiede, Christian and von Bonin, Malte and Schetelig, Johannes and Kramer, Michael and Berdel, Wolfgang E. and Ehninger, Gerhard}, title={Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML)}, subtitle={a multicentre, phase 2, randomised controlled trial}, year={2015}, pages={1691-1699}, language={eng}, issn={1474-5488}, volume={16}, number={16}, note={Gesehen am 02.07.2020}, journal={The lancet}, doi={10.1016/S1470-2045(15)00362-9}, } @article{UBHD-68138563, author={R{\"o}llig, Christoph and Ho, Anthony Dick and Kr{\"a}mer, Alwin}, title={Allogeneic stem-cell transplantation in patients with NPM1-mutated acute myeloid leukemia}, subtitle={results from a prospective donor versus no-donor analysis of patients after upfront HLA typing within the SAL-AML 2003 tria}, year={2015}, pages={403-410}, language={eng}, issn={1527-7755}, volume={33}, number={5}, note={Published online: December 29, 2014 ; Gesehen am 14.07.2017}, journal={Journal of clinical oncology}, doi={10.1200/JCO.2013.54.4973}, } @article{UBHD-68639776, author={R{\"o}llig, Christoph and Kr{\"a}mer, Alwin and M{\"u}ller-Tidow, Carsten and Schliemann, Christoph and Mikesch, Jan-Henrik and Steffen, Bj{\"o}rn and Kr{\"a}mer, Alwin and Noppeney, Richard and Sch{\"a}fer-Eckart, Kerstin and Krause, Stefan W. and H{\"a}nel, Mathias and Herbst, Regina and Kunzmann, Volker and Einsele, Hermann and Jost, Edgar and Br{\"u}mmendorf, Tim H. and Scholl, Sebastian and Hochhaus, Andreas and Neubauer, Andreas and Sohlbach, Kristina and Fransecky, Lars and Kaufmann, Martin and Niemann, Dirk and Schaich, Markus and Frickhofen, Norbert and Kiani, Alexander and Heits, Frank and Kr{\"u}mpelmann, Ulrich and Kaiser, Ulrich and Kullmer, Johannes and Wass, Maxi and St{\"o}lzel, Friedrich and von Bonin, Malte and Middeke, Jan Moritz and Thiede, Christian and Schetelig, Johannes and Berdel, Wolfgang E. and Ehninger, Gerhard and Baldus, Claudia D. and Platzbecker, Uwe and Serve, Hubert and Bornh{\"a}user, Martin}, title={Does time from diagnosis to treatment affect the prognosis of patients with newly diagnosed acute myeloid leukemia?}, year={2020}, pages={823-830}, language={eng}, issn={1528-0020}, volume={136}, number={7}, note={Gesehen am 23.09.2020}, journal={Blood}, doi={10.1182/blood.2019004583}, } @article{UBHD-68565010, author={R{\"o}llig, Christoph and Kr{\"a}mer, Alwin}, title={Intermediate-dose cytarabine plus mitoxantrone versus standard-dose cytarabine plus daunorubicin for acute myeloid leukemia in elderly patients}, year={2018}, pages={973-978}, language={eng}, issn={1569-8041}, volume={29}, number={4}, note={Elektronische Reproduktion der Druckausgabe ; Available online 7 January 2020 ; Gesehen am 16.04.2020}, journal={Annals of oncology}, doi={10.1093/annonc/mdy030}, } @article{UBHD-69180438, author={R{\"o}llig, Christoph and Herold, Sylvia and Sauer, Tim and Brandts, Christian Hubertus and Steffen, Bj{\"o}rn and Sch{\"a}fer-Eckart, Kerstin and Krause, Stefan W. and H{\"a}nel, Mathias and Reichle, Albrecht and Scholl, Sebastian and Neubauer, Andreas and Mikesch, Jan-Henrik and Schetelig, Johannes and St{\"o}lzel, Friedrich and Kramer, Michael and Haake, Annett and Frimmel, Julia and Kr{\"a}mer, Alwin and Schlenk, Richard Friedrich and Platzbecker, Uwe and Serve, Hubert and Baldus, Claudia and M{\"u}ller-Tidow, Carsten and Aust, Daniela E. and Bornh{\"a}user, Martin and Ehninger, Gerhard and Thiede, Christian}, title={Midostaurin in addition to intensive chemotherapy in acute myeloid leukemia with t(8;21) and KIT and/or FLT3- ITD mutations}, subtitle={results of the SAL MIDOKIT trial : letter to the editor}, year={2023}, pages={2520-2525}, language={eng}, issn={1592-8721}, volume={108}, number={9 vom: Sept.}, note={Online verf{\"u}gbar: 9. Februar 2023 ; Gesehen am 08.02.2024}, journal={Haematologica}, doi={10.3324/haematol.2022.281636}, } @article{UBHD-68295738, author={R{\"o}llig, Christoph and Kr{\"a}mer, Alwin}, title={Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia}, year={2012}, pages={1062-1067}, language={eng}, issn={1029-2403}, volume={53}, number={6}, note={Published online: 07 December 2011 ; Gesehen am 15.08.2018}, journal={Leukemia and lymphoma}, doi={10.3109/10428194.2011.637210}, } @article{UBHD-68243158, author={Rønnest, Mads H. and Raab, Marc-Steffen and Anderhub, Simon and Kr{\"a}mer, Alwin}, title={Disparate SAR data of Griseofulvin analogues for the dermatophytes trichophyton mentagrophytes, T. rubrum, and MDA-MB-231 cancer cells}, year={2012}, pages={652-660}, language={eng}, issn={1520-4804}, volume={55}, number={2}, note={Published online December 19, 2011 ; Gesehen am 16.04.2018}, journal={Journal of medicinal chemistry}, doi={10.1021/jm200835c}, } @article{UBHD-68965347, author={Rønnest, Mads H. and Nielsen, M. T. and Leber, B. and Mortensen, U. H. and Kr{\"a}mer, Alwin and Clausen, M. H. and Larsen, T. O. and Harris, P.}, title={(+)-Geodin from Aspergillus terreus}, year={2011}, pages={o125-o128}, language={eng}, issn={2053-2296 and 1600-5759}, volume={67}, number={3}, note={Gesehen am 19.09.2022}, journal={Acta crystallographica}, doi={10.1107/S0108270111005816}, } @article{UBHD-69143103, author={Ross, Jeffrey S. and Sokol, Ethan S. and Moch, Holger and Mileshkin, Linda and Baciarello, Giulia and Losa, Ferran and Beringer, Andreas and Thomas, Marlene and Elvin, Julia A. and Ngo, Nhu and Jin, Dexter X. and Kr{\"a}mer, Alwin}, title={Comprehensive genomic profiling of carcinoma of unknown primary origin}, subtitle={retrospective molecular classification considering the CUPISCO study design}, year={2021}, pages={e394-e402}, language={eng}, issn={1549-490X}, volume={26}, number={3 vom: M{\"a}rz}, note={Online ver{\"o}ffentlicht: 14. Dezember 2020 ; Gesehen am 15.11.2023}, journal={The oncologist}, doi={10.1002/onco.13597}, } @article{UBHD-68971254, author={Schaich, Markus and R{\"o}llig, Christoph and Soucek, Silke and Kramer, Michael and Thiede, Christian and Mohr, Brigitte and Oelschlaegel, Uta and Schmitz, Norbert and Stuhlmann, Reingard and Wandt, Hannes and Sch{\"a}fer-Eckart, Kerstin and Aulitzky, Walter and Kaufmann, Martin and Bodenstein, Heinrich and Tischler, Joachim and Ho, Anthony Dick and Kr{\"a}mer, Alwin and Bornh{\"a}user, Martin and Schetelig, Johannes and Ehninger, Gerhard}, title={Cytarabine dose of 36 g/m2 compared with 12 g/m2 within first consolidation in acute myeloid leukemia}, subtitle={results of patients enrolled onto the prospective randomized AML96 study}, year={2011}, pages={2696-2702}, language={eng}, issn={1527-7755}, volume={29}, number={19}, note={Im Titel ist die Zahl 2 jeweils hochgestellt ; Gesehen am 07.10.2022}, journal={Journal of clinical oncology}, doi={10.1200/JCO.2010.33.7303}, } @article{UBHD-68807902, author={Schneeweiss, Andreas and Sinn, Peter and Ehemann, Volker and Khbeis, Tanja and Neben, Kai and Krause, Ulf and Ho, Anthony Dick and Bastert, Gunther and Kr{\"a}mer, Alwin}, title={Centrosomal aberrations in primary invasive breast cancer are associated with nodal status and hormone receptor expression}, year={2003}, pages={346-352}, language={eng}, issn={1097-0215}, volume={107}, number={3}, note={Gesehen am 03.12.2021}, journal={International journal of cancer}, doi={10.1002/ijc.11408}, } @article{UBHD-68884073, author={Schultheis, Beate and Kr{\"a}mer, Alwin and Willer, Andreas and Hegenbart, Ute and Goldschmidt, Hartmut and Hehlmann, R{\"u}diger}, title={Analysis of p73 and p53 gene deletions in multiple myeloma}, year={1999}, pages={2099-2103}, language={eng}, issn={1476-5551}, volume={13}, number={12}, note={Gesehen am 01.03.2022}, journal={Leukemia}, doi={10.1038/sj.leu.2401609}, } @article{UBHD-68807884, author={Seggewiß-Bernhardt, Ruth and Ho, Anthony Dick and Kr{\"a}mer, Alwin}, title={Remarkable response to rituximab in a patient with atypical CD20++ mantle cell lymphoma of the bone marrow leading to severe pancytopenia}, year={2004}, pages={316-318}, language={eng}, issn={1432-0584}, volume={83}, number={5}, note={Published online: 13 November 2003 ; Die Pluszeichen im Titel sind hochgestellt ; Gesehen am 03.12.2021}, journal={Annals of hematology}, doi={10.1007/s00277-003-0793-z}, } @article{UBHD-69088949, author={Sellner, Leopold and Capper, David and Meyer, Jochen and Langhans, Claus-Dieter and Hartog, Christine-Maria and Pfeifer, Heike Angelika and Serve, Hubert and Ho, Anthony Dick and Okun, J{\"u}rgen G. and Kr{\"a}mer, Alwin and Deimling, Andreas von}, title={Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations}, year={2010}, pages={457-459}, language={eng}, issn={1600-0609}, volume={85}, number={5}, note={Gesehen am 23.06.2023}, journal={European journal of haematology}, doi={10.1111/j.1600-0609.2010.01505.x}, } @article{UBHD-68991099, author={Sertel, Serkan and Fu, Yujie and Zu, Yuangang and Rebacz, Blanka Kamila and Konkimalla, Badireenath and Plinkert, Peter K. and Kr{\"a}mer, Alwin and Gertsch, J{\"u}rg and Efferth, Thomas}, title={Molecular docking and pharmacogenomics of Vinca alkaloids and their monomeric precursors, vindoline and catharanthine}, year={2011}, pages={723-735}, language={eng}, issn={1873-2968}, volume={81}, number={6 vom: M{\"a}rz}, note={Gesehen am 30.11.2022}, journal={Biochemical pharmacology}, doi={10.1016/j.bcp.2010.12.026}, } @article{UBHD-68588480, author={Stasik, Sebastian and Kr{\"a}mer, Alwin and M{\"u}ller-Tidow, Carsten}, title={EZH2 mutations and impact on clinical outcome}, subtitle={an analysis in 1,604 patients with newly diagnosed acute myeloid leukemia}, year={2020}, pages={e228-e231}, language={eng}, issn={1592-8721}, volume={105}, number={5}, note={Im Text ist EZH2 schr{\"a}g gestellt ; Gesehen am 18.06.2020}, journal={Haematologica}, doi={10.3324/haematol.2019.222323}, } @article{UBHD-68826348, author={Stasik, Sebastian and Eckardt, Jan-Niklas and Kramer, Michael and R{\"o}llig, Christoph and Kr{\"a}mer, Alwin and Scholl, Sebastian and Hochhaus, Andreas and Crysandt, Martina and Br{\"u}mmendorf, Tim H. and Naumann, Ralph and Steffen, Bj{\"o}rn and Kunzmann, Volker and Einsele, Hermann and Schaich, Markus and Burchert, Andreas and Neubauer, Andreas and Sch{\"a}fer-Eckart, Kerstin and Schliemann, Christoph and Krause, Stefan and Herbst, Regina and H{\"a}nel, Mathias and Frickhofen, Norbert and Noppeney, Richard and Kaiser, Ulrich and Baldus, Claudia D. and Kaufmann, Martin and Rácil, Zdenek and Platzbecker, Uwe and Berdel, Wolfgang E. and Mayer, Jiri and Serve, Hubert and M{\"u}ller-Tidow, Carsten and Ehninger, Gerhard and Bornh{\"a}user, Martin and Schetelig, Johannes and Middeke, Jan M. and Thiede, Christian}, title={Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia}, year={2021}, pages={3279-3289}, language={eng}, issn={2473-9537}, volume={5}, number={17}, note={Gesehen am 15.12.2021}, journal={Blood advances}, doi={10.1182/bloodadvances.2021004631}, } @article{UBHD-69140844, author={Stein, Stefan and Ott, Marion G. and Schultze-Straßer, Stephan and Jauch, Anna and Burwinkel, Barbara and Kinner, Andrea and Schmidt, Manfred and Kr{\"a}mer, Alwin and Schw{\"a}ble, Joachim and Glimm, Hanno and K{\"o}hl, Ulrike and Preiss, Carolin and Ball, Claudia R. and Martin, Hans and G{\"o}hring, Gudrun and Schwarzw{\"a}lder, Kerstin and Hofmann, Wolf-Karsten and Karakaya, Kadin and Tchatchou, Sandrine and Yang, Rongxi and Reinecke, Petra and K{\"u}hlcke, Klaus and Schlegelberger, Brigitte and Thrasher, Adrian J. and Hoelzer, Dieter and Seger, Reinhard and Kalle, Christof von and Grez, Manuel}, title={Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease}, year={2010}, pages={198-204}, language={eng}, issn={1546-170X}, volume={16}, number={2}, note={Gesehen am 08.11.2023}, journal={Nature medicine}, doi={10.1038/nm.2088}, } @article{UBHD-68578268, author={St{\"o}lzel, Friedrich and Bochtler, Tilmann and Kr{\"a}mer, Alwin}, title={Karyotype complexity and prognosis in acute myeloid leukemia}, year={2016}, pages={7 S.}, language={eng}, issn={2044-5385}, volume={6(2016) Artikel-Nummer e386}, number={7 Seiten}, note={Gesehen am 15.05.2020}, journal={Blood cancer journal}, doi={10.1038/bcj.2015.114}, } @article{UBHD-68877140, author={Sucker, Christoph and Kr{\"a}mer, Alwin and Moos, Marion and Goldschmidt, Hartmut}, title={Concomitant chronic lymphocytic leukemia and multiple myeloma}, subtitle={proof of common clonal origin}, year={2004}, pages={81-84}, language={eng}, issn={1613-9089}, volume={3}, number={2}, note={Gesehen am 11.02.2022}, journal={The Chinese-german journal of clinical oncology}, doi={10.1007/s10330-004-0264-6}, } @article{UBHD-69053706, author={Sumbalova Koledova, Zuzana and Kr{\"a}mer, Alwin and Kafkova, Leona Raskova and Divoky, Vladimir}, title={Cell-cycle regulation in embryonic stem cells}, subtitle={centrosomal decisions on self-renewal}, year={2010}, pages={1663-1678}, language={eng}, issn={1557-8534}, volume={19}, number={11 vom: Nov.}, note={Gesehen am 21.03.2023}, journal={Stem Cells and Development}, doi={10.1089/scd.2010.0136}, } @article{UBHD-69053703, author={Sumbalova Koledova, Zuzana and Kafkova, Leona Raskova and Kr{\"a}mer, Alwin and Divoky, Vladimir}, title={DNA damage-induced degradation of Cdc25A does not lead to inhibition of Cdk2 activity in mouse embryonic stem cells}, year={2010}, pages={450-461}, language={eng}, issn={1549-4918}, volume={28}, number={3 vom: M{\"a}rz}, note={Gesehen am 21.03.2023}, journal={Stem cells}, doi={10.1002/stem.311}, } @article{UBHD-68970405, author={Taube, Franziska and Georgi, Julia Annabell and Kramer, Michael and Stasik, Sebastian and Middeke, Jan Moritz and R{\"o}llig, Christoph and Krug, Utz and Kr{\"a}mer, Alwin and Scholl, Sebastian and Hochhaus, Andreas and Br{\"u}mmendorf, Tim H. and Naumann, Ralph and Petzold, Andreas and Mulet-Lazaro, Roger and Valk, Peter J. M. and Steffen, Bj{\"o}rn and Einsele, Hermann and Schaich, Markus and Burchert, Andreas and Neubauer, Andreas and Sch{\"a}fer-Eckart, Kerstin and Schliemann, Christoph and Krause, Stefan W. and H{\"a}nel, Mathias and Noppeney, Richard and Kaiser, Ulrich and Baldus, Claudia D. and Kaufmann, Martin and Herold, Sylvia and St{\"o}lzel, Friedrich and Sockel, Katja and von Bonin, Malte and M{\"u}ller-Tidow, Carsten and Platzbecker, Uwe and Berdel, Wolfgang E. and Serve, Hubert and Ehninger, Gerhard and Bornh{\"a}user, Martin and Schetelig, Johannes and Thiede, Christian}, title={CEBPA mutations in 4708 patients with acute myeloid leukemia}, subtitle={differential impact of bZIP and TAD mutations on outcome}, year={2022}, pages={87-103}, language={eng}, issn={1528-0020}, volume={139}, number={1 vom: 6. Jan.}, note={Online verf{\"u}gbar 30 July 2021, Version des Artikels 6 January 2022 ; Gesehen am 05.10.2022}, journal={Blood}, doi={10.1182/blood.2020009680}, } @article{UBHD-69041802, author={Vit, Gianmatteo and Hirth, Alexander and Neugebauer, Nicolas and Kraft, Bianca and Sigismondo, Gianluca and Cazzola, Anna and Teßmer, Claudia and Duro, Joana and Krijgsveld, Jeroen and Hofmann, Ilse and Berger, Michael and Kl{\"u}ter, Harald and Niehrs, Christof and Nilsson, Jakob and Kr{\"a}mer, Alwin}, title={Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption}, year={2022}, pages={1-12}, language={eng}, issn={2058-7716}, volume={8}, number={Artikel-ID 484}, note={Gesehen am 15.02.2023}, journal={Cell death discovery}, doi={10.1038/s41420-022-01274-0}, } @article{UBHD-68286005, author={Vulprecht, Julia and Tibelius, Alexandra and Konotop, Gleb and Liu, Fengying and Raab, Marc-Steffen and Kr{\"a}mer, Alwin}, title={STIL is required for centriole duplication in human cells}, year={2012}, pages={1353-1362}, language={eng}, issn={1477-9137}, volume={125}, number={5}, note={Published online April 6, 2012 ; Gesehen am 16.07.2018}, journal={Journal of cell science}, doi={10.1242/jcs.104109}, } @article{UBHD-68621436, author={Wagner, Verena and Hose, Dirk and Seckinger, Anja and Weiz, Ludmila and Meißner, Tobias and Breitkreutz, Iris and Podar, Klaus and Ho, Anthony Dick and Goldschmidt, Hartmut and Kr{\"a}mer, Alwin and Raab, Marc-Steffen}, title={Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1}, year={2014}, pages={10237-10250}, language={eng}, issn={1949-2553}, volume={5}, number={21}, note={Gesehen am 28.07.2020}, journal={OncoTarget}, doi={10.18632/oncotarget.2529}, } @article{UBHD-69206867, author={Westphalen, Christoph Benedikt and Federer-Gsponer, Joël and Pauli, C. and Karapetyan, A. R. and Chalabi, N. and Durán-Pacheco, G. and Beringer, A. and Bochtler, Tilmann and Cook, N. and H{\"o}glander, E. and Jin, D. X. and Losa, F. and Mileshkin, L. and Moch, H. and Ross, J. S. and Sokol, E. S. and Tothill, R. W. and Kr{\"a}mer, Alwin}, title={Baseline mutational profiles of patients with carcinoma of unknown primary origin enrolled in the CUPISCO study☆}, year={2023}, pages={1-9}, language={eng}, issn={2059-7029}, volume={8}, note={Online ver{\"o}ffentlicht am 2 November 2023 ; Gesehen am 23.04.2024}, journal={ESMO open}, doi={10.1016/j.esmoop.2023.102035}, } @article{UBHD-68200729, author={Witzens-Harig, Mathias and Klemmer, Jennifer and Brandt, Julia and Brants, Elke and Meißner, Julia and Dreger, Peter and Lengfelder, Eva and Kr{\"a}mer, Alwin and Ho, Anthony Dick}, title={Rituximab maintenance improves survival in male patients with diffuse large B-cell lymphoma}, subtitle={results of the HD2002 prospective multicentre randomized phase III trial}, year={2015}, pages={710-719}, language={eng}, issn={1365-2141}, volume={171}, number={5}, note={Gesehen am 12.12.2017}, journal={British journal of haematology}, doi={10.1111/bjh.13652}, } @article{UBHD-68741913, author={Yu, Weijia and Lutz, Christoph and Kr{\"a}mer, Alwin and Schmidt-Zachmann, Marion S.}, title={The JmjC-domain protein NO66/RIOX-1 affects the balance between proliferation and maturation in acute myeloid leukemia}, year={2021}, pages={1-14}, language={eng}, issn={1090-2422}, volume={402}, note={Gesehen am 28.05.2021}, journal={Experimental cell research}, doi={10.1016/j.yexcr.2021.112566}, }