@article{UBHD-68404464, author={Elßner, Christin and Goeppert, Benjamin and Longerich, Thomas and Scherr, Anna-Lena and Rupp, Christian and Kather, Jakob Nikolas and Kautz, Nicole and Breuhahn, Kai and Gdynia, Georg and R{\"o}ssler, Stephanie and Schirmacher, Peter and J{\"a}ger, Dirk and Sch{\"o}lch, Sebastian and K{\"o}hler, Bruno Christian}, title={Nuclear translocation of RELB is increased in diseased human liver and promotes ductular reaction and biliary fibrosis in mice}, year={2019}, pages={30 S.}, language={eng}, issn={1528-0012}, volume={156(2019}, note={Available online 13 November 2018 ; Gesehen am 04.07.2019}, journal={Gastroenterology}, doi={10.1053/j.gastro.2018.11.018}, } @article{UBHD-68635187, author={Healy, Marc Eamonn and Scherr, Anna-Lena and Schulze-Bergkamen, Henning and Heikenw{\"a}lder, Mathias}, title={MCL1 is required for maintenance of intestinal homeostasis and prevention of carcinogenesis in mice}, year={2020}, pages={183-199}, language={eng}, issn={1528-0012}, volume={159}, number={1}, note={Gesehen am 07.09.2020}, journal={Gastroenterology}, doi={10.1053/j.gastro.2020.03.017}, } @article{UBHD-68714959, author={K{\"o}hler, Bruno Christian and Scherr, Anna-Lena and Lorenz, Stephan and Urbanik, Toni and Kautz, Nicole and Elßner, Christin and Welte, Stefan Ezechiel and Lorenzo Bermejo, Justo and J{\"a}ger, Dirk and Schulze-Bergkamen, Henning}, title={Beyond cell death}, subtitle={antiapoptotic Bcl-2 proteins regulate migration and invasion of colorectal cancer cells in vitro}, year={2013}, pages={1-12}, language={eng}, issn={1932-6203}, volume={8}, note={Gesehen am 15.12.2021}, journal={PLOS ONE}, doi={10.1371/journal.pone.0076446}, } @article{UBHD-68616755, author={K{\"o}hler, Bruno Christian and Jassowicz, Adam and Scherr, Anna-Lena and Lorenz, Stephan and Radhakrishnan, Praveen and Kautz, Nicole and Elßner, Christin and Weiß, Johanna and J{\"a}ger, Dirk and Schneider, Martin and Schulze-Bergkamen, Henning}, title={Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling}, year={2015}, language={eng}, issn={1471-2407}, volume={15(2015) Artikel-Nummer 919}, number={11 Seiten}, note={Gesehen am 14.07.2020}, journal={BMC cancer}, doi={10.1186/s12885-015-1929-y}, } @article{UBHD-67869281, author={K{\"o}hler, Bruno Christian and Scherr, Anna-Lena and Lorenz, Stephan and Elßner, Christin and Kautz, Nicole and Welte, Stefan Ezechiel and J{\"a}ger, Dirk and Urbanik, Toni and Schulze-Bergkamen, Henning}, title={Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells}, year={2014}, pages={11 S.}, language={eng}, issn={1932-6203}, volume={9(2014}, note={Gesehen am 07.09.2015}, journal={PLOS ONE}, doi={10.1371/journal.pone.0106571}, } @book{UBHD-67942672, author={K{\"o}hler, Bruno Christian and Jassowicz, Adam and Scherr, Anna-Lena and Lorenz, Stephan and Radhakrishnan, Praveen and Kautz, Nicole and Elßner, Christin and Weiß, Johanna and J{\"a}ger, Dirk and Schneider, Martin and Schulze-Bergkamen, Henning}, title={Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling}, publisher={Biomed Central}, address={London}, year={2015}, pages={1 Online-Ressource (11 Seiten)}, language={eng}, note={Aus: BMC Cancer, 15(2015), Nr. 919, pp 1-11. ISSN 1471-2407}, } @article{UBHD-68571333, author={K{\"o}hler, Bruno Christian and Scherr, Anna-Lena and Bruckner, Thomas and Gdynia, Georg and J{\"a}ger, Dirk and Mueller, Sebastian and Seitz, Helmut K.}, title={Possible nechanisms of ethanol-mediated colorectal carcinogenesis}, subtitle={the role of Cytochrome P4502E1, Etheno-DNA Adducts, and the Anti-Apoptotic Protein Mcl-1}, year={2016}, pages={2094-2101}, language={eng}, issn={1530-0277}, volume={40}, number={10}, note={Gesehen am 28.04.2020}, journal={Alcoholism}, doi={10.1111/acer.13180}, } @article{UBHD-68452064, author={Radhakrishnan, Praveen and Ruh, Nadine and Harnoß, Jonathan M. and Kiss, Judit and Mollenhauer, Martin and Scherr, Anna-Lena and Platzer, Lisa K. and Schmidt, Thomas and Podar, Klaus and Weitz, J{\"u}rgen and Schulze-Bergkamen, Henning and K{\"o}hler, Bruno Christian and Ulrich, Alexis and Schneider, Martin}, title={Prolyl hydroxylase 3 attenuates MCL-1-mediated ATP production to suppress the metastatic potential of colorectal cancer cells}, year={2016}, pages={2219-2230}, language={eng}, issn={1538-7445}, volume={76}, number={8}, note={Gesehen am 07.11.2019}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-15-1474}, } @article{UBHD-68330322, author={Scherr, Anna-Lena and Gdynia, Georg and Haffa, Mariam and Radhakrishnan, Praveen and Heller, Anette and Keim, Sophia and Kautz, Nicole and Jassowicz, Adam and Elßner, Christin and J{\"a}ger, Dirk and Schneider, Martin and K{\"o}hler, Bruno Christian}, title={Bcl-xL is an oncogenic driver in colorectal cancer}, year={2016}, pages={10 S.}, language={eng}, issn={2041-4889}, volume={7}, note={Gesehen am 20.11.2018 ; Im Titel ist "L" in Bcl-xL tiefgestellt}, journal={Cell death & disease}, doi={10.1038/cddis.2016.233}, } @article{UBHD-69183534, author={Scherr, Anna-Lena and Nader, Luisa and Xu, Kaiyu and Elssner, Christin and Ridder, Dirk A. and Nichetti, Federico and Mastel, Manuel and Fritzsche, Sarah and Kelmendi, Eblina and Schmitt, Nathalie and Hoffmeister-Wittmann, Paula and Hoffmeister-Wittmann, Paula and Weiler, Sofia Maria Elisabeth and Korell, Felix and Albrecht, Thomas and Schwab, Maximilian and Isele, Hanna and Kessler, Annika and H{\"u}llein, Jennifer and Seretny, Agnieszka and Ye, Liangtao and Urbanik, Toni and Welte, Stefan and Leblond, Anne-Laure and Heilig, Christoph E. and Rahbari, Mohammad and Ali, Sheikh Adnan and Gallage, Suchira and Lenoir, Bénédicte and Wilhelm, Nina and G{\"a}rtner, Ulrike and Ogrodnik, Simon J. and Springfeld, Christoph and Tschaharganeh, Darjus-Felix and Fr{\"o}hling, Stefan and Longerich, Thomas and Schulze-Bergkamen, Henning and J{\"a}ger, Dirk and Brandl, Lydia and Schirmacher, Peter and Straub, Beate Katharina and Weber, Achim and De Toni, Enrico N. and Goeppert, Benjamin and Heikenwalder, Mathias and Jackstadt, René-Filip and R{\"o}ssler, Stephanie and Breuhahn, Kai and K{\"o}hler, Bruno Christian}, title={Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC}, year={2024}, pages={278-294}, language={eng}, issn={1527-3350}, volume={80}, number={2}, note={Gesehen am 19.02.2024}, journal={Hepatology}, doi={10.1097/HEP.0000000000000657}, } @article{UBHD-68671426, author={Scherr, Anna-Lena and Mock, Andreas and Gdynia, Georg and Schmitt, Nathalie and Heilig, Christoph E. and Korell, Felix and Rhadakrishnan, Praveen and Hoffmeister-Wittmann, Paula and Metzeler, Klaus H. and Schulze-Osthoff, Klaus and Illert, Anna Lena and B{\"o}rries, Melanie and Trojan, J{\"o}rg and Waidmann, Oliver and Falkenhorst, Johanna and Siveke, Jens and Jost, Philipp J. and Bitzer, Michael and Malek, Nisar P. and Vecchione, Loredana and Jelas, Ivan and Brors, Benedikt and Glimm, Hanno and Stenzinger, Albrecht and Grekova, Svetlana and Gehrig, Tobias and Schulze-Bergkamen, Henning and J{\"a}ger, Dirk and Schirmacher, Peter and Heikenwalder, Mathias and Goeppert, Benjamin and Schneider, Martin and Fr{\"o}hling, Stefan and K{\"o}hler, Bruno Christian}, title={Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer}, year={2020}, pages={1-16}, language={eng}, issn={2041-4889}, volume={11}, number={10}, note={Gesehen am 10.12.2020}, journal={Cell death & disease}, doi={10.1038/s41419-020-03092-7}, url={https://doi.org/10.1038/s41419-020-03092-7}, library={UB}, } @article{UBHD-68576404, author={Scherr, Anna-Lena and Jassowicz, Adam and Pató, Anna and Elßner, Christin and Ismail, Lars and Schmitt, Nathalie and Hoffmeister-Wittmann, Paula and Neukirch, Lasse and Gdynia, Georg and Goeppert, Benjamin and Schulze-Bergkamen, Henning and J{\"a}ger, Dirk and K{\"o}hler, Bruno Christian}, title={Knockdown of Atg7 induces nuclear-LC3 dependent apoptosis and augments chemotherapy in colorectal cancer cells}, year={2020}, language={eng}, issn={1422-0067 and 1661-6596}, volume={21(2020}, note={Gesehen am 13.05.2020}, journal={International journal of molecular sciences}, doi={10.3390/ijms21031099}, } @book{UBHD-68098746, author={Scherr, Anna-Lena}, organization={Universit{\"a}t Heidelberg}, title={The role of anti-apoptotic Bcl-2 proteins for colorectal cancer development and progression}, address={Heidelberg}, year={2017}, pages={152 Bl{\"a}tter}, language={eng}, school={Dissertation, Ruperto-Carola University of Heidelberg, 2017}, keywords={Zelltod / Dickdarmkrebs}, library={UB [Signatur: 2017 U 197]}, } @book{UBHD-68183480, author={Scherr, Anna-Lena}, title={The role of anti-apoptotic Bcl-2 proteins for colorectal cancer development and progression}, address={Heidelberg}, year={2017}, pages={1 Online-Ressource (152 Seiten)}, language={eng}, school={Dissertation, Ruperto-Carola University of Heidelberg, 2017}, doi={10.11588/heidok.00022654}, keywords={Zelltod / Dickdarmkrebs}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-226545}, library={UB}, } @article{UBHD-68955698, author={Sobol, Benjamin and Azzam Nieto, Osama and Eberlein, Emily Lara and Scherr, Anna-Lena and Ismail, Lars and Keßler, Annika and Nader, Luisa and Schwab, Maximilian and Hoffmeister-Wittmann, Paula and Schmitt, Nathalie and J{\"a}ger, Dirk and Welte, Stefan Ezechiel and Seidensaal, Katharina and Christopoulos, Petros and Heilig, Christoph E. and Kriegsmann, Katharina and Fr{\"o}hling, Stefan and Kriegsmann, Mark and Heß, Jochen and K{\"o}hler, Bruno Christian}, title={Specific targeting of antiapoptotic Bcl-2 proteins as a radiosensitizing approach in solid tumors}, year={2022}, pages={1-13}, language={eng}, issn={1422-0067 and 1661-6596}, volume={23}, note={Gesehen am 19.08.2022}, journal={International journal of molecular sciences}, doi={10.3390/ijms23147850}, } @article{UBHD-69181143, author={Tisch, Nathalie and Mogler, Carolin and Stojanovic, Ana and Luck, Robert and Korhonen, Emilia Anne and Ellerkmann, Alexander and Adler, Heike and Singhal, Mahak and Schermann, Géza and Erkert, Lena and Patankar, Jay V and Karakatsani, Andromachi and Scherr, Anna-Lena and Fuchs, Yaron and Cerwenka, Adelheid and Wirtz, Stefan and K{\"o}hler, Bruno Christian and Augustin, Hellmut and Becker, Christoph and Schmidt, Thomas and Ruiz de Almodóvar, Carmen}, title={Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice}, year={2022}, pages={1-21}, language={eng}, issn={1757-4684}, volume={14}, note={Gesehen am 12.02.2024}, journal={EMBO molecular medicine}, doi={10.15252/emmm.202114121}, } @article{UBHD-67835324, author={Urbanik, Toni and K{\"o}hler, Bruno Christian and Wolpert, Laura and Elßner, Christin and Scherr, Anna-Lena and Longerich, Thomas and Kautz, Nicole and Welte, Stefan Ezechiel and H{\"o}velmeyer, Nadine and J{\"a}ger, Dirk and Waismann, Ari and Schulze-Bergkamen, Henning}, title={CYLD deletion triggers nuclear factor-kappa B-signaling and increases cell death resistance in murine hepatocytes}, year={2014}, pages={17049-17064}, language={eng}, issn={2219-2840}, volume={20}, number={45}, note={Gesehen am 24.06.2015}, journal={World journal of gastroenterology}, doi={10.3748/wjg.v20.i45.17049}, } @article{UBHD-69364958, author={Xu, Kaiyu and Kessler, Annika and Nichetti, Federico and Hoffmeister-Wittmann, Paula and Scherr, Anna-Lena and Nader, Luisa and Kelmendi, Eblina and Schmitt, Nathalie and Schwab, Maximilian and García-Beccaria, María and Sobol, Benjamin and Azzam Nieto, Osama and Isele, Hanna and G{\"a}rtner, Ulrike and Vaquero-Siguero, Nuria and Volk, Julia and Korell, Felix and Mock, Andreas and Heide, Danijela and Ramadori, Pierluigi and Lenoir, Bénédicte and Albrecht, Thomas and H{\"u}llein, Jennifer and J{\"a}ger, Dirk and Fr{\"o}hling, Stefan and Springfeld, Christoph and Jackstadt, Rene and Heikenw{\"a}lder, Mathias and Dill, Michael T. and R{\"o}ssler, Stephanie and Goeppert, Benjamin and K{\"o}hler, Bruno Christian}, title={Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma}, year={2024}, pages={2950-2963}, language={eng}, issn={1478-3231}, volume={44}, number={11 vom: Nov.}, note={Zuerst ver{\"o}ffentlicht: 20. August 2024 ; Gesehen am 11.07.2025}, journal={Liver international}, doi={10.1111/liv.16069}, }