@article{UBHD-68245112, author={Adlung, Lorenz and Wuchter, Patrick and Ho, Anthony Dick and Schilling, Marcel and H{\"o}fer, Thomas and Klingm{\"u}ller, Ursula}, title={Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation}, year={2017}, pages={25 S.}, language={eng}, issn={1744-4292}, volume={13(2017}, note={Gesehen am 11.12.2018}, journal={Molecular systems biology}, doi={10.15252/msb.20167258}, } @article{UBHD-68305730, author={Albrecht, Marco and Stichel, Damian and M{\"u}ller, Benedikt and Sticht, Carsten and Gretz, Norbert and Klingm{\"u}ller, Ursula and Breuhahn, Kai and Matth{\"a}us, Franziska}, title={TTCA}, subtitle={an R package for the identification of differentially expressed genes in time course microarray data}, year={2017}, pages={11 S.}, language={eng}, issn={1471-2105}, volume={18(2017) Artikel-Nummer 33}, number={11 Seiten}, note={Gesehen am 18.09.2018}, journal={BMC bioinformatics}, doi={10.1186/s12859-016-1440-8}, } @book{UBHD-68498397, author={Ammerpohl, Ole and Firnkorn, Daniel and Goldmann, Torsten and Huber, Rudolf M. and Klingm{\"u}ller, Ursula and Meister, Michael and Muley, Thomas and Olchers, Till and Reck, Martin and Risch, Angela and Schw{\"o}rer, Florian and S{\"u}ltmann, Holger and Teucher, Birgit and Thomas, Michael and Tufman, Amanda L. H. and Watermann, Ines and Wessels, Sabine}, organization={Thoraxklinik Heidelberg and Deutsches Zentrum f{\"u}r Lungenforschung}, title={Umfassende Charakterisierung von nicht-kleinzelligem Lungenkarzinom anhand integrierter klinischer und molekularer Analyse}, subtitle={Schlussbericht zum Verwendungsnachweis : Laufzeit des Vorhabens: 01.07.2013-31.12.2016}, publisher={Thoraxklinik am Universit{\"a}tsklinikum Heidelberg}, address={Heidelberg}, year={2016}, pages={23, 3 ungez{\"a}hlte Bl{\"a}tter}, language={ger}, note={F{\"o}rderkennzeichen BMBF 82DZL20402 - 82DZL20404 - 82DZL20104 - 82DZL20105 - 82DZL20302 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, keywords={Lungenkrebs}, } @book{UBHD-68498398, author={Ammerpohl, Ole and Firnkorn, Daniel and Goldmann, Torsten and Huber, Rudolf M. and Klingm{\"u}ller, Ursula and Meister, Michael and Muley, Thomas and Olchers, Till and Reck, Martin and Risch, Angela and Schw{\"o}rer, Florian and S{\"u}ltmann, Holger and Teucher, Birgit and Thomas, Michael and Tufman, Amanda L. H. and Watermann, Ines and Wessels, Sabine}, organization={Thoraxklinik Heidelberg and Deutsches Zentrum f{\"u}r Lungenforschung}, title={Umfassende Charakterisierung von nicht-kleinzelligem Lungenkarzinom anhand integrierter klinischer und molekularer Analyse}, subtitle={Schlussbericht zum Verwendungsnachweis : Laufzeit des Vorhabens: 01.07.2013-31.12.2016}, publisher={Thoraxklinik am Universit{\"a}tsklinikum Heidelberg}, address={Heidelberg}, year={2016}, pages={1 Online-Ressource (27 Seiten, 1,86 MB)}, language={ger}, note={F{\"o}rderkennzeichen BMBF 82DZL20402 - 82DZL20404 - 82DZL20104 - 82DZL20105 - 82DZL20302 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, doi={10.2314/GBV:89088952X}, keywords={Lungenkrebs}, } @article{UBHD-68613087, author={Apweiler, Rolf and Beissbarth, Tim and Berthold, Michael and Bl{\"u}thgen, Nils and Burmeister, Yvonne and Dammann, Olaf and Deutsch, Andreas and Feuerhake, Friedrich and Franke, Andre and Hasenauer, Jan and Hoffmann, Steve and H{\"o}fer, Thomas and Jansen, Peter LM and Kaderali, Lars and Klingm{\"u}ller, Ursula and Koch, Ina and Kohlbacher, Oliver and Kuepfer, Lars and Lammert, Frank and Maier, Dieter and Pfeifer, Nico and Radde, Nicole and Rehm, Markus and Roeder, Ingo and Saez-Rodriguez, Julio and Sax, Ulrich and Schmeck, Bernd and Schuppert, Andreas and Seilheimer, Bernd and Theis, Fabian J. and Vera, Julio and Wolkenhauer, Olaf}, title={Whither systems medicine?}, year={2018}, pages={6 S.}, language={eng}, issn={2092-6413}, volume={50(2018}, note={Gesehen am 02.07.2020}, journal={Experimental & molecular medicine}, doi={10.1038/emm.2017.290}, } @incollection{UBHD-69000173, author={Becker, Verena and Schilling, Marcel and Bachmann, Julie and Baumann, Ute and Raue, Andreas and Maiwald, Thomas and Timmer, Jens and Klingm{\"u}ller, Ursula}, title={Covering a broad dynamic range}, subtitle={information processing at the erythropoietin receptor}, year={2010}, pages={1404-1408}, language={eng}, issn={1095-9203}, note={Gesehen am 21.12.2022}, booktitle={Science}, doi={10.1126/science.1184913}, } @incollection{UBHD-68334931, author={Becker, Verena and Timmer, Jens and Klingm{\"u}ller, Ursula}, title={Receptor dynamics in signaling}, year={2012}, pages={313-323}, language={eng}, isbn={9781441972101}, note={First online: 18 November 2011 ; Gesehen am 03.2.2018}, booktitle={Advances in systems biology}, } @article{UBHD-68314282, author={Bochtler, Tilmann and Kirsch, Michael and Klingm{\"u}ller, Ursula and Ho, Anthony Dick and Kr{\"a}mer, Alwin}, title={Centrosomal targeting of tyrosine kinase activity does not enhance oncogenicity in chronic myeloproliferative disorders}, year={2012}, pages={728-735}, language={eng}, issn={1476-5551}, volume={26}, number={4}, note={Gesehen am 11.10.2018 ; Published online 21 October 2011}, journal={Leukemia}, doi={10.1038/leu.2011.283}, } @article{UBHD-68265335, author={Breitkopf-Heinlein, Katja and Meyer, Christoph and K{\"o}nig, Courtney and Gaitantzi, Haristi and Cai, Chen and Li, Qi and Valous, Nektarios A. and Klingm{\"u}ller, Ursula and Ilkavets, Iryna and Wieland, Matthias and Ebert, Matthias and Augustin, Hellmut and Dooley, Steven}, title={BMP-9 interferes with liver regeneration and promotes liver fibrosis}, year={2017}, pages={939-954}, language={eng}, issn={1468-3288}, volume={66}, number={5}, note={Gesehen am 26.06.2018}, journal={Gut}, doi={10.1136/gutjnl-2016-313314}, } @article{UBHD-68935241, author={Castoldi, Mirco and Spasić Vujić, Maja and Altamura, Sandro and Elmén, Joacim and Lindow, Morten and Kiss, Judit and Stolte, Jens and Sparla, Richard and D'Alessandro, Lorenza and Klingm{\"u}ller, Ursula and Fleming, Robert E. and Longerich, Thomas and Gr{\"o}ne, Hermann-Josef and Benes, Vladimir and Kauppinen, Sakari and Hentze, Matthias W. and Muckenthaler, Martina}, title={The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice}, year={2011}, pages={1386-1396}, language={eng}, issn={1558-8238}, volume={121}, number={4}, note={Gesehen am 28.06.2022}, journal={The journal of clinical investigation}, doi={10.1172/JCI44883}, } @article{UBHD-67251391, author={Castoldi, Mirco and Spasić Vujić, Maja and Altamura, Sandro and Elmén, Joacim and Lindow, Morten and Kiss, Judit and Stolte, Jens and Sparla, Richard and D'Alessandro, Lorenza and Klingm{\"u}ller, Ursula and Fleming, Robert E. and Longerich, Thomas and Gr{\"o}ne, Hermann-Josef and Benes, Vladimir and Kauppinen, Sakari and Hentze, Matthias W. and Muckenthaler, Martina}, title={The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice}, year={2011}, pages={1386-1396}, language={eng}, issn={0021-9738}, volume={121}, number={4}, journal={The journal of clinical investigation}, } @article{UBHD-68996506, author={Chakraborty, Sajib and Andrieux, Geoffroy and Kastl, Philipp and Adlung, Lorenz and Altamura, Sandro and Boehm, Martin E. and Schwarzm{\"u}ller, Luisa E. and Abdullah, Yomn and Wagner, Marie-Christine and Helm, Barbara and Gr{\"o}ne, Hermann-Josef and Lehmann, Wolf-Dieter and B{\"o}rries, Melanie and Busch, Hauke and Muckenthaler, Martina and Schilling, Marcel and Klingm{\"u}ller, Ursula}, title={Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo}, year={2022}, pages={1-18}, language={eng}, issn={2211-1247}, volume={40}, note={Das PDF enth{\"a}lt zus{\"a}tzlich einen Anhang von 8 Seiten ; Gesehen am 13.12.2022}, journal={Cell reports}, doi={10.1016/j.celrep.2022.111360}, } @article{UBHD-68648516, author={D'Alessandro, Lorenza and Hoehme, S. and Henney, A. and Drasdo, D. and Klingm{\"u}ller, Ursula}, title={Unraveling liver complexity from molecular to organ level}, subtitle={challenges and perspectives}, year={2015}, pages={78-86}, language={eng}, issn={1873-1732}, volume={117}, number={1}, note={Available online 26 November 2014 ; Gesehen am 14.10.2020}, journal={Progress in biophysics & molecular biology}, doi={10.1016/j.pbiomolbio.2014.11.005}, } @article{UBHD-69044520, author={Dehlke, Karolin and Krause, Linda and Tyufekchieva, Silvana and Murtha-Lemekhova, Anastasia and Mayer, Philipp and Vlasov, Artyom and Klingm{\"u}ller, Ursula and Mueller, Nikola S. and Hoffmann, Katrin}, title={Predicting liver regeneration following major resection}, year={2022}, pages={1-13}, language={eng}, issn={2045-2322}, volume={12}, number={Artikel-ID 13396}, note={Gesehen am 24.02.2022}, journal={Scientific reports}, doi={10.1038/s41598-022-16968-9}, url={https://doi.org/10.1038/s41598-022-16968-9}, library={UB}, } @article{UBHD-69263435, author={Díaz-Jiménez, Alberto and Ramos, Maria and Helm, Barbara and Chocarro, Sara and Frey, Dario and Agrawal, Shubham and Somogyi, Kálmán and Klingm{\"u}ller, Ursula and Lu, Junyan and Sotillo, Rocio}, title={Concurrent inhibition of ALK and SRC kinases disrupts the ALK lung tumor cell proteome}, year={2024}, pages={101081-1-101081-18}, language={eng}, issn={1532-2084}, volume={74}, number={Artikel-ID 101081}, note={Gesehen am 18.10.2024}, journal={Drug resistance updates}, doi={10.1016/j.drup.2024.101081}, } @article{UBHD-68586751, author={Doleschel, Dennis and Rix, Anne and Arns, Susanne and Palmowski, Karin and Gremse, Felix and Merkle, Ruth and Schw{\"o}rer, Florian and Klingm{\"u}ller, Ursula and Jarsch, Michael and Kiessling, Fabian and Lederle, Wiltrud}, title={Erythropoietin improves the accumulation and therapeutic effects of carboplatin by enhancing tumor vascularization and perfusion}, year={2015}, pages={905-918}, language={eng}, issn={1838-7640}, volume={5}, number={8}, note={Gesehen am 15.06.2020}, journal={Theranostics}, doi={10.7150/thno.11304}, } @article{UBHD-68571156, author={D{\"u}rr, Julia and Leitz, Dominik and Szczygieł, Magdalena and Dvornikov, Dmytro and Fraumann, Simon and Kreutz, Clemens and Zadora, Piotr Kamil and Seyhan Agircan, Ayca and Konietzke, Philip and Engelmann, Theresa A. and Hegermann, Jan and Mulugeta, Surafel and Kawabe, Hiroshi and Knudsen, Lars and Ochs, Matthias and Rotin, Daniela and Muley, Thomas and Kreuter, Michael and Herth, Felix and Wielp{\"u}tz, Mark Oliver and Beers, Michael F. and Klingm{\"u}ller, Ursula and Mall, Marcus A.}, title={Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice}, year={2020}, pages={1-18}, language={eng}, issn={2041-1723}, volume={11}, number={Artikel-ID 2012}, note={Gesehen am 03.02.2025}, journal={Nature Communications}, doi={10.1038/s41467-020-15743-6}, } @article{UBHD-69006758, author={Gegner, Hagen M. and Naake, Thomas and Dugourd, Aurélien and M{\"u}ller, Torsten and Czernilofsky, Felix and Kliewer, Georg and J{\"a}ger, Evelyn and Helm, Barbara and Kunze-Rohrbach, Nina and Klingm{\"u}ller, Ursula and Hopf, Carsten and M{\"u}ller-Tidow, Carsten and Dietrich, Sascha and Sáez Rodríguez, Julio and Huber, Wolfgang and Hell, R{\"u}diger and Poschet, Gernot and Krijgsveld, Jeroen}, title={Pre-analytical processing of plasma and serum samples for combined proteome and metabolome analysis}, year={2022}, pages={1-13}, language={eng}, issn={2296-889X}, volume={9}, number={Artikel-ID 961448}, note={Gesehen am 16.01.2023}, journal={Frontiers in molecular biosciences}, doi={10.3389/fmolb.2022.961448}, url={https://doi.org/10.3389/fmolb.2022.961448}, library={UB}, } @article{UBHD-68240955, author={Gente, Karolina and Spasić Vujić, Maja and Sch{\"a}fer, Sebastian Markus and Stolte, Jens and Baehr-Ivacevic, Tomi and Waldow, Katharina and Zhou-Suckow, Zhe and Klingm{\"u}ller, Ursula and Benes, Vladimir and Mall, Marcus A. and Muckenthaler, Martina}, title={Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation}, year={2012}, pages={12 S.}, language={eng}, issn={1932-6203}, volume={7(2012}, note={Gesehen am 09.04.2018}, journal={PLOS ONE}, doi={10.1371/journal.pone.0039363}, } @article{UBHD-69116930, author={Hammad, Seddik and Ogris, Christoph and Othman, Amnah and Erdoesi, Pia and Schmidt-Heck, Wolfgang and Biermayer, Ina and Helm, Barbara and Gao, Yan and Piorońska, Weronika and Holland, Christian H. and D'Alessandro, Lorenza and Torre, Carolina de la and Sticht, Carsten and Al Aoua, Sherin and Theis, Fabian J. and Bantel, Heike and Ebert, Matthias and Klingm{\"u}ller, Ursula and Hengstler, Jan G. and Dooley, Steven and Mueller, Nikola S.}, title={Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation}, year={2023}, pages={1-13}, language={eng}, issn={2041-4889}, volume={14}, note={Ver{\"o}ffentlicht: 12. Juli 2023 ; Gesehen am 29.08.2023}, journal={Cell death & disease}, doi={10.1038/s41419-023-05855-4}, } @article{UBHD-69166802, author={Hiebinger, Felix and Kudulyte, Aiste and Chi, Huanting and Burbano De Lara Carrillo, Sebastian Rodrigo and Ilic, Doroteja and Helm, Barbara and Welsch, Hendrik and Dao Thi, Viet Loan and Klingm{\"u}ller, Ursula and Binder, Marco}, title={Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression}, year={2023}, pages={1-12}, language={eng}, issn={1475-2867}, volume={23}, note={Gesehen am 29.01.2024}, journal={Cancer cell international}, doi={10.1186/s12935-023-03150-y}, } @article{UBHD-69231682, author={Horvat, Natalie and Chocarro, Sara and Marques, Oriana and Bauer, Tobias A. and Qiu, Ruiyue and Díaz-Jiménez, Alberto and Helm, Barbara and Chen, Yuanyuan and Sawall, Stefan and Sparla, Richard and Su, Lu and Klingm{\"u}ller, Ursula and Barz, Matthias and Hentze, Matthias W. and Sotillo, Rocio and Muckenthaler, Martina}, title={Superparamagnetic iron oxide nanoparticles reprogram the tumor microenvironment and reduce lung cancer regrowth after Crizotinib treatment}, year={2024}, pages={11025-11041}, language={eng}, issn={1936-086X}, volume={18}, number={17}, note={Gesehen am 09.07.2024}, journal={ACS nano}, doi={10.1021/acsnano.3c08335}, } @article{UBHD-68852755, author={Hug, Sabine and Raue, Andreas and Hasenauer, J. and Bachmann, J. and Klingm{\"u}ller, Ursula and Timmer, J. and Theis, Fabian J.}, title={High-dimensional Bayesian parameter estimation}, subtitle={case study for a model of JAK2/STAT5 signaling}, year={2013}, pages={293-304}, language={eng}, issn={1879-3134}, volume={246}, number={2}, note={Gesehen am 22.12.2021}, journal={Mathematical biosciences}, doi={10.1016/j.mbs.2013.04.002}, } @article{UBHD-68244555, author={Kallenberger, Stefan M. and Unger, Anne Lucia Katharina and Klingm{\"u}ller, Ursula and Eils, Roland and Herten, Dirk-Peter}, title={Correlated receptor transport processes buffer single-cell heterogeneity}, year={2017}, pages={14 S.}, language={eng}, issn={1553-7358}, volume={13(2017}, note={Gesehen am 19.04.2018}, journal={PLoS Computational Biology}, doi={10.1371/journal.pcbi.1005779}, url={http://dx.doi.org/10.1371/journal.pcbi.1005779}, library={UB}, } @article{UBHD-68656931, author={Kim-Wanner, Soo-Zin and Assenov, Yassen and Nair, Mridul Balakrishnan and Weichenhan, Dieter and Benner, Axel and Becker, Natalia and Landwehr, Katharina and Kuner, Ruprecht and S{\"u}ltmann, Holger and Esteller, Manel and Koch, Ina and Lindner, Michael and Meister, Michael and Thomas, Michael and Bieg, Matthias and Klingm{\"u}ller, Ursula and Schlesner, Matthias and Warth, Arne and Brors, Benedikt and Seifried, Erhard and B{\"o}nig, Halvard and Plass, Christoph and Risch, Angela and Muley, Thomas}, title={Genome-wide DNA methylation profiling in early stage I lung adenocarcinoma reveals predictive aberrant methylation in the promoter region of the long noncoding RNA PLUT}, subtitle={an exploratory study}, year={2020}, pages={1338-1350}, language={eng}, issn={1556-1380}, volume={15}, number={8}, note={Gesehen am 03.11.2020}, journal={Journal of thoracic oncology}, doi={10.1016/j.jtho.2020.03.023}, } @book{UBHD-2575294, author={Klingm{\"u}ller, Ursula}, title={Interaktion des Enten-Hepatitis-B-Virus (DHBV) mit prim{\"a}ren Entenleberzellen}, subtitle={Charakterisierung des viralen Liganden und Nachweis des zellul{\"a}ren Rezeptors}, year={1992}, language={ger}, school={Heidelberg, Univ., Diss., 1992}, library={UB [Signatur: 92 MN 131] ; UB [Signatur: 92 U 869]}, } @article{UBHD-68641608, author={Kok, Frédérique and Rosenblatt, Marcus and Teusel, Melissa and Nizharadze, Tamar and Gonçalves Magalhães, Vladimir and D{\"a}chert, Christopher and Maiwald, Tim and Vlasov, Artyom and W{\"a}sch, Marvin and Tyufekchieva, Silvana and Hoffmann, Katrin and Damm, Georg and Seehofer, Daniel and B{\"o}ttler, Tobias and Binder, Marco and Timmer, Jens and Schilling, Marcel and Klingm{\"u}ller, Ursula}, title={Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction}, year={2020}, pages={32 S.}, language={eng}, issn={1744-4292}, volume={16(2020}, note={Gesehen am 30.09.2020}, journal={Molecular systems biology}, doi={10.15252/msb.20198955}, } @article{UBHD-69054740, author={Kowarsch, Andreas and Bl{\"o}chl, Florian and Bohl, Sebastian and Saile, Maria and Gretz, Norbert and Klingm{\"u}ller, Ursula and Theis, Fabian J.}, title={Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation}, year={2010}, pages={1-14}, language={eng}, issn={1471-2105}, volume={11}, number={Artikel-ID 585}, note={Gesehen am 22.03.2023}, journal={BMC bioinformatics}, doi={10.1186/1471-2105-11-585}, } @article{UBHD-68162207, author={Kuchenov, Dmitry and Schw{\"o}rer, Florian and Klingm{\"u}ller, Ursula and Schultz, Carsten}, title={High-content imaging platform for profiling intracellular signaling network activity in living cells}, year={2016}, pages={1550-1559}, language={eng}, issn={2451-9448}, volume={23}, number={12}, note={Gesehen am 05.09.2017}, journal={Cell chemical biology}, doi={10.1016/j.chembiol.2016.11.008}, } @article{UBHD-68250367, author={Lucarelli, Philippe and Hoffmann, Katrin and Muciek, Maria and Gretz, Norbert and Klingm{\"u}ller, Ursula}, title={Resolving the combinatorial complexity of smad protein complex formation and its link to gene expression}, year={2018}, pages={75-89}, language={eng}, issn={2405-4720}, volume={6}, number={1}, note={Gesehen am 08.05.2018}, journal={Cell systems}, doi={10.1016/j.cels.2017.11.010}, } @article{UBHD-68300907, author={Maiwald, Thomas and Schilling, Marcel and Becker, Verena and Klingm{\"u}ller, Ursula}, title={In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems}, year={2012}, pages={11 S.}, language={eng}, issn={1752-0509}, volume={6(2012) Artikel-Nummer 13}, number={11 Seiten}, note={Gesehen am 31.08.2018}, journal={BMC systems biology}, doi={10.1186/1752-0509-6-13}, } @article{UBHD-68117434, author={Maiwald, Tim and Sahle, Sven and Gretz, Norbert and Kummer, Ursula and Klingm{\"u}ller, Ursula}, title={Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling}, year={2010}, pages={4741-4754}, language={eng}, issn={1742-4658}, volume={277}, number={22}, note={Gesehen am 09.05.2017}, journal={The FEBS journal}, doi={10.1111/j.1742-4658.2010.07880.x}, } @article{UBHD-68214461, author={Marwitz, Sebastian and Depner, Sofia and Dvornikov, Dmytro and Merkle, Ruth and Szczygieł, Magdalena and M{\"u}ller-Decker, Karin and Lucarelli, Philippe and W{\"a}sch, Marvin and Mairb{\"a}url, Heimo and Rabe, Klaus F. and K{\"u}gler, Christian and Vollmer, Ekkehard Karl Ludwig and Reck, Martin and Scheufele, Swetlana and Kr{\"o}ger, Maren and Ammerpohl, Ole and Siebert, Reiner and Goldmann, Torsten and Klingm{\"u}ller, Ursula}, title={Downregulation of the TGFb pseudoreceptor BAMBI in non-small cell lung cancer enhances TGFb signaling and invasion}, year={2016}, pages={3785-3801}, language={eng}, issn={1538-7445}, volume={76}, number={13}, note={Gesehen am 29.01.2018}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-15-1326}, } @article{UBHD-68558854, author={Melnik, Svitlana and Dvornikov, Dmytro and M{\"u}ller-Decker, Karin and Depner, Sofia and Stannek, Peter and Meister, Michael and Warth, Arne and Thomas, Michael and Muley, Thomas and Risch, Angela and Plass, Christoph and Klingm{\"u}ller, Ursula and Niehrs, Christof and Glinka, Andrei}, title={Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification}, year={2018}, pages={1-17}, language={eng}, issn={2056-5968}, volume={4}, number={Artikel-ID 37}, note={Gesehen am 26.03.2020}, journal={Cell discovery}, doi={10.1038/s41421-018-0033-2}, } @article{UBHD-68327349, author={Meyer, René and D'Alessandro, Lorenza and Kaschek, Daniel and Lehmann, Wolf-Dieter and H{\"o}fer, Thomas and Klingm{\"u}ller, Ursula}, title={Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration}, year={2012}, pages={14 S.}, language={eng}, issn={1664-042X}, volume={3}, number={Artikel-ID 451}, note={Gesehen am 12.11.2018}, journal={Frontiers in physiology}, doi={10.3389/fphys.2012.00451}, } @article{UBHD-68734637, author={Mohapatra, Soumya Ranjan and Sadik, Ahmed and Sharma, Suraj and Poschet, Gernot and Gegner, Hagen M. and Lanz, Tobias and Lucarelli, Philippe and Klingm{\"u}ller, Ursula and Platten, Michael and Heiland, Ines and Opitz, Christiane}, title={Hypoxia routes tryptophan homeostasis towards increased tryptamine production}, year={2021}, pages={1-13}, language={eng}, issn={1664-3224}, volume={12}, number={Artikel-ID 590532}, note={Gesehen am 06.05.2021}, journal={Frontiers in immunology}, doi={10.3389/fimmu.2021.590532}, } @article{UBHD-68032793, author={M{\"u}ller, Stephanie and Huang, Xiaoyun and B{\"o}rner, Kathleen and Grimm, Dirk and Klingm{\"u}ller, Ursula}, title={T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes}, year={2015}, pages={23 S.}, language={eng}, issn={1744-4292}, volume={11(2015}, note={Gesehen am 27.09.2016}, journal={Molecular systems biology}, doi={10.15252/msb.20156032}, } @article{UBHD-68403996, author={Oppelt, Angela and Kaschek, Daniel and Huppelschoten, Suzanna and Sison-Young, Rowena and Zhang, Fang and Buck-Wiese, Marie and Herrmann, Franziska and Malkusch, Sebastian and Kr{\"u}ger, Carmen L. and Meub, Mara and Merkt, Benjamin and Zimmermann, Lea and Schofield, Amy and Jones, Robert P. and Malik, Hassan and Schilling, Marcel and Heilemann, Mike and Water, Bob van de and Goldring, Christopher E. and Park, B. Kevin and Timmer, Jens and Klingm{\"u}ller, Ursula}, title={Model-based identification of TNFα-induced IKKβ-mediated and I[kappa]Bα-mediated regulation of NF[kappa]B signal transduction as a tool to quantify the impact of drug-induced liver injury compounds}, year={2018}, pages={16 S.}, language={eng}, issn={2056-7189}, volume={4(2018}, number={1) Artikel-Nummer 23}, note={Gesehen am 03.07.2019}, journal={npj Systems biology and applications}, doi={10.1038/s41540-018-0058-z}, } @article{UBHD-69070606, author={Pfeifer, Andrea and Kaschek, Daniel and Bachmann, Julie and Klingm{\"u}ller, Ursula and Timmer, Jens}, title={Model-based extension of high-throughput to high-content data}, year={2010}, pages={1-13}, language={eng}, issn={1752-0509}, volume={4(2010) vom: Aug.}, number={Artikel-ID 106}, note={Gesehen am 02.05.2023}, journal={BMC systems biology}, doi={10.1186/1752-0509-4-106}, } @article{UBHD-68122302, author={Pinna, Federico and Sahle, Sven and Beuke, Katharina and Bissinger, Michaela and Aydin, Selcan and D'Alessandro, Lorenza and Gauges, Ralph and Raue, Andreas and Timmer, Jens and Klingm{\"u}ller, Ursula and Schirmacher, Peter and Kummer, Ursula and Breuhahn, Kai}, title={A systems biology study on NF[kappa]B signaling in primary mouse hepatocytes}, year={2012}, pages={14 S.}, language={eng}, issn={1664-042X}, volume={3}, note={Gesehen am 23.05.2017}, journal={Frontiers in physiology}, doi={10.3389/fphys.2012.00466}, } @article{UBHD-68962894, author={Raia, Valentina and Schilling, Marcel and B{\"o}hm, Martin and Hahn, Bettina and Kowarsch, Andreas and Raue, Andreas and Sticht, Carsten and Bohl, Sebastian and Saile, Maria and M{\"o}ller, Peter and Gretz, Norbert and Timmer, Jens and Theis, Fabian and Lehmann, Wolf-Dieter and Lichter, Peter and Klingm{\"u}ller, Ursula}, title={Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets}, year={2011}, pages={693-704}, language={eng}, issn={1538-7445}, volume={71}, number={3}, note={Gesehen am 09.09.2022}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-10-2987}, } @article{UBHD-67209545, author={Raia, Valentina and Schilling, Marcel and B{\"o}hm, Martin and Hahn, Bettina and Kowarsch, Andreas and Raue, Andreas and Sticht, Carsten and Bohl, Sebastian and Saile, Maria and M{\"o}ller, Peter and Gretz, Norbert and Timmer, Jens and Theis, Fabian and Lehmann, Wolf-Dieter and Lichter, Peter and Klingm{\"u}ller, Ursula}, title={Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets}, year={2011}, pages={693-704}, language={eng}, issn={0008-5472}, volume={71}, number={3}, journal={Cancer research}, } @article{UBHD-69306906, author={Richtmann, Sarah and Marwitz, Sebastian and Muley, Thomas and Koistinen, Hannu and Christopoulos, Petros and Thomas, Michael and Kazdal, Daniel and Allg{\"a}uer, Michael and Winter, Hauke and Goldmann, Torsten and Meister, Michael and Klingm{\"u}ller, Ursula and Schneider, Marc}, title={The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer}, year={2024}, pages={177-189}, language={eng}, issn={1878-1810}, volume={272(2024) vom: Okt.}, note={Online verf{\"u}gbar: 13. M{\"a}rz 2024, Artikelversion: 28. Juni 2024 ; Gesehen am 21.02.2025}, journal={Translational research}, doi={10.1016/j.trsl.2024.02.007}, } @article{UBHD-68660384, author={Robichon, Katharina and Maiwald, Tim and Schilling, Marcel and Kopp-Schneider, Annette and Willemsen, Joschka and Schw{\"o}rer, Florian and Teusel, Melissa and Kreutz, Clemens and Ehlting, Christian and Huang, Jun and Chakraborty, Sajib and Huang, Xiaoyun and Damm, Georg and Seehofer, Daniel and Lang, Philipp A. and Bode, Johannes G. and Binder, Marco and Bartenschlager, Ralf and Timmer, Jens and Klingm{\"u}ller, Ursula}, title={Identification of interleukin1β as an amplifier of interferon alpha-induced antiviral responses}, year={2020}, language={eng}, issn={1553-7374}, volume={16(2020}, note={Gesehen am 12.11.2020}, journal={PLoS pathogens}, doi={10.1371/journal.ppat.1008461}, } @article{UBHD-69168499, author={Samarin, Jana and Fabrowski, Piotr and Kurilov, Roman and Nůsková, Hana and Hummel-Eisenbeiß, Johanna and Pink, Hannelore and Li, Nan and Weru, Vivienn and Alborzinia, Hamed and Yildiz, Umut and Grob, Laura and T{\"a}ubert, Minerva Jazmin and Czech, Marie and Morgen, Michael and Brandst{\"a}dter, Christina and Becker, Katja and Mao, Lianghao and Jayavelu, Ashok Kumar and Goncalves, Angela and Uhrig, Ulrike and Seiler, Jeanette and Lyu, Yanhong and Diederichs, Sven and Klingm{\"u}ller, Ursula and Muckenthaler, Martina and Kopp-Schneider, Annette and Teleman, Aurelio A. and Miller, Aubry K. and Gunkel, Nikolas}, title={Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs}, year={2023}, pages={1-19}, language={eng}, issn={2213-2317}, volume={62}, number={Artikel-ID 102639}, note={Gesehen am 01.02.2024}, journal={Redox Biology}, doi={10.1016/j.redox.2023.102639}, } @article{UBHD-68300000, author={Schilling, Marcel and Klingm{\"u}ller, Ursula}, title={Mathematical modeling of hematological malignancies}, year={2012}, pages={1648-1653}, language={eng}, issn={1945-0508}, volume={E4}, number={1}, note={Gesehen am 29.08.2018}, journal={Frontiers in bioscience}, } @article{UBHD-68274797, author={Schneider, Marc and Christopoulos, Petros and Muley, Thomas and Warth, Arne and Klingm{\"u}ller, Ursula and Thomas, Michael and Herth, Felix and Dienemann, Hendrik and Meister, Michael}, title={AURKA, DLGAP5, TPX2, KIF11 and CKAP5}, subtitle={five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients}, year={2017}, pages={365-372}, language={eng}, issn={1791-2423}, volume={50}, number={2}, note={Published online 2017 Jan 2 ; Gesehen am 27.06.2018}, journal={International journal of oncology}, doi={10.3892/ijo.2017.3834}, } @article{UBHD-68299571, author={Sobotta, Svantje and Lehmann, Wolf-Dieter and Gretz, Norbert and Schilling, Marcel and Klingm{\"u}ller, Ursula}, title={Model based targeting of IL-6-induced inflammatory responses in cultured primary hepatocytes to improve application of the JAK inhibitor ruxolitinib}, year={2017}, pages={25 S.}, language={eng}, issn={1664-042X}, volume={8(2017) Artikel-Nummer 775}, number={25 Seiten}, note={Gesehen am 28.08.2018}, journal={Frontiers in physiology}, doi={10.3389/fphys.2017.00775}, } @article{UBHD-68244218, author={Stichel, Damian and Middleton, Alistair and M{\"u}ller, Benedikt and Depner, Sofia and Klingm{\"u}ller, Ursula and Breuhahn, Kai and Matth{\"a}us, Franziska}, title={An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors}, year={2017}, pages={5}, language={eng}, issn={2056-7189}, volume={3}, number={1}, note={Gesehen am 01.09.2020}, journal={npj Systems biology and applications}, doi={10.1038/s41540-017-0006-3}, } @article{UBHD-67210001, author={St{\"o}hr, Katharina and Siegberg, Daniel Wolfgang and Ehrhard, Tanja and Lymperopoulos, Konstantinos and {\"O}z, Aliye Simin and Schulmeister, Sonja Elke and Pfeifer, Andrea and Bachmann, Julie and Klingm{\"u}ller, Ursula and Sourjik, Victor and Herten, Dirk-Peter}, title={Quenched substrates for live-cell labeling of SNAP-tagged fusion proteins with improved fluorescent background}, year={2010}, pages={8186-8193}, language={eng}, issn={0003-2700}, volume={82}, number={19}, journal={Analytical chemistry}, } @article{UBHD-69116163, author={St{\"o}hr, Katharina and Siegberg, Daniel Wolfgang and Ehrhard, Tanja and Lymperopoulos, Konstantinos and {\"O}z, Aliye Simin and Schulmeister, Sonja Elke and Pfeifer, Andrea and Bachmann, Julie and Klingm{\"u}ller, Ursula and Sourjik, Victor and Herten, Dirk-Peter}, title={Quenched substrates for live-cell labeling of SNAP-tagged fusion proteins with improved fluorescent background}, year={2010}, pages={8186-8193}, language={eng}, issn={1520-6882}, volume={82}, number={19}, note={Gesehen am 25.08.2023}, journal={Analytical chemistry}, doi={10.1021/ac101521y}, } @article{UBHD-68121902, author={Wegner, Katja and Bachmann, Anastasia and Schad, Jan-Ulrich and Lucarelli, Philippe and Sahle, Sven and Nickel, Peter J. and Meyer, Christoph and Klingm{\"u}ller, Ursula and Dooley, Steven and Kummer, Ursula}, title={Dynamics and feedback loops in the transforming growth factor β signaling pathway}, year={2012}, pages={22-34}, language={eng}, issn={1873-4200}, volume={162}, note={Gesehen am 22.05.2017}, journal={Biophysical chemistry}, doi={10.1016/j.bpc.2011.12.003}, } @article{UBHD-69328597, author={Wesener, Marie C. and Weiler, Sofia Maria Elisabeth and Bissinger, Michaela and Klessinger, Tobias F. and Rose, Fabian and Merker, Sabine and Luzarowski, Marcin and Ruppert, Thomas and Helm, Barbara and Klingm{\"u}ller, Ursula and Schirmacher, Peter and Breuhahn, Kai}, title={CRKL enhances YAP signaling through binding and JNK/JUN pathway activation in liver cancer}, year={2024}, pages={1-18}, language={eng}, issn={1422-0067 and 1661-6596}, volume={25}, note={Gesehen am 07.04.2025}, journal={International journal of molecular sciences}, doi={10.3390/ijms25158549}, } @article{UBHD-68680721, author={Wessels, Sabine and Muley, Thomas and Christopoulos, Petros and Meister, Michael and Heinzmann-Groth, Ingrid and Warth, Arne and Herpel, Esther and Hummler, Simone and Klingm{\"u}ller, Ursula and Kuon, Jonas and Heußel, Claus Peter and Eberhardt, Ralf and Herth, Felix and Winter, Hauke and Bischoff, Helge and Stenzinger, Albrecht and Thomas, Michael and Schneider, Marc}, title={Comprehensive serial biobanking in advanced NSCLC}, subtitle={feasibility, challenges and perspectives}, year={2020}, pages={1000-1014}, language={eng}, issn={2226-4477}, volume={9}, number={4}, note={Gesehen am 26.10.2021}, journal={Translational Lung Cancer Research}, doi={10.21037/tlcr-20-137}, } @article{UBHD-69127844, author={Wolf, Stephanie and Ehlting, Christian and M{\"u}ller-Dott, Sophia and Poschmann, Gereon and Petzsch, Patrick and Lautwein, Tobias and Wang, Sai and Helm, Barbara and Schilling, Marcel and Sáez Rodríguez, Julio and Vucur, Mihael and St{\"u}hler, Kai and K{\"o}hrer, Karl and Tacke, Frank and Dooley, Steven and Klingm{\"u}ller, Ursula and Luedde, Tom and Bode, Johannes G.}, title={Hepatocytes reprogram liver macrophages involving control of TGF-β activation, influencing liver regeneration and injury}, year={2023}, pages={1-17}, language={eng}, issn={2471-254X}, volume={7}, note={Gesehen am 09.10.2023}, journal={Hepatology communications}, doi={10.1097/HC9.0000000000000208}, }