@article{UBHD-68657397, author={Abu-Remaileh, Monther and Bender, Sebastian and Raddatz, G{\"u}nter and Ansari, Ihab and Cohen, Daphne and Gutekunst, Julian and Musch, Tanja and Linhart, Heinz and Breiling, Achim and Pikarsky, Eli and Bergman, Yehudit and Lyko, Frank}, title={Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer}, year={2015}, pages={2120-2130}, language={eng}, issn={1538-7445}, volume={75}, number={10}, note={Gesehen am 04.11.2020}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-14-3295}, } @article{UBHD-68867356, author={Bormann, Felix and Tuorto, Francesca and Cirzi, Cansu and Lyko, Frank and Legrand, Carine}, title={BisAMP}, subtitle={a web-based pipeline for targeted RNA cytosine-5 methylation analysis}, year={2019}, pages={121-127}, language={eng}, issn={1095-9130}, volume={156}, note={Gesehen am 17.01.2022 ; Online publiziert am 24. Oktober 2018}, journal={Methods}, doi={10.1016/j.ymeth.2018.10.013}, } @article{UBHD-68559657, author={Bormann, Felix and Rodríguez Paredes, Manuel and Lasitschka, Felix and Edelmann, Dominic and Musch, Tanja and Benner, Axel and Bergman, Yehudit and Dieter, Sebastian M. and Ball, Claudia R. and Glimm, Hanno and Linhart, Heinz G. and Lyko, Frank}, title={Cell-of-origin DNA methylation signatures are maintained during colorectal carcinogenesis}, year={2018}, pages={3407-3418}, language={eng}, issn={2211-1247}, volume={23}, number={11}, note={Gesehen am 31.03.2020}, journal={Cell reports}, doi={10.1016/j.celrep.2018.05.045}, } @article{UBHD-68768450, author={Cunha Navarro, Isabela and Tuorto, Francesca and Jordan, David and Legrand, Carine and Price, Jonathan and Braukmann, Fabian and Hendrick, Alan G and Akay, Alper and Kotter, Annika and Helm, Mark and Lyko, Frank and Miska, Eric}, title={Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans}, year={2021}, pages={1-18}, language={eng}, issn={1460-2075}, volume={40}, note={Ver{\"o}ffentlicht am 7. Dezember 2020 ; Gesehen am 10.08.2021}, journal={The EMBO journal}, doi={10.15252/embj.2020105496}, } @article{UBHD-68676924, author={Durdevic, Zeljko and Hanna, Katharina and Gold, Beth and Pollex, Tim and Cherry, Sara and Lyko, Frank and Schaefer, Matthias R.}, title={Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2}, year={2013}, pages={269-275}, language={eng}, issn={1469-3178}, volume={14}, number={3}, note={Gesehen am 05.01.2021}, journal={EMBO reports}, doi={10.1038/embor.2013.3}, } @article{UBHD-68676925, author={Durdevic, Zeljko and Mobin, Mehrpouya Balaghy and Hanna, Katharina and Lyko, Frank and Schaefer, Matthias R.}, title={The RNA methyltransferase Dnmt2 is required for efficient Dicer-2-dependent siRNA pathway activity in drosophila}, year={2013}, pages={931-937}, language={eng}, issn={2211-1247}, volume={4}, number={5}, note={Gesehen am 05.01.2021}, journal={Cell reports}, doi={10.1016/j.celrep.2013.07.046}, } @article{UBHD-68704079, author={Falckenhayn, Cassandra and Boerjan, Bart and Raddatz, G{\"u}nter and Frohme, Marcus and Schoofs, Liliane and Lyko, Frank}, title={Characterization of genome methylation patterns in the desert locust Schistocerca gregaria}, year={2013}, pages={1423-1429}, language={eng}, issn={1477-9145}, volume={216}, number={8}, note={Gesehen am 25.02.2021}, journal={The journal of experimental biology}, doi={10.1242/jeb.080754}, } @article{UBHD-68575812, author={Falckenhayn, Cassandra and Carneiro, Vitor Coutinho and Amarante, Anderson de Mendonça and Schmid, Katharina and Hanna, Katharina and Kang, Seokyoung and Helm, Mark and Dimopoulos, George and Fantappié, Marcelo Rosado and Lyko, Frank}, title={Comprehensive DNA methylation analysis of the Aedes aegypti genome}, year={2016}, language={eng}, issn={2045-2322}, volume={6(2016) Artikel-Nummer 36444}, number={8 Seiten}, note={Gesehen am 12.05.2020}, journal={Scientific reports}, doi={10.1038/srep36444}, } @book{UBHD-68324973, author={Gatzmann, Fanny and Falckenhayn, Cassandra and Gutekunst, Julian and Raddatz, G{\"u}nter and Coutinho Carneiro, Vitor and Lyko, Frank}, title={The methylome of the marbled crayfish links gene body methylation to stable expression of poorly accessible genes}, publisher={BioMed Central}, address={London}, year={2018}, pages={1 Online-Ressource (Seite 1-12)}, language={eng}, note={Aus: Epigenetics & Chromatin, 11 (2018), Nr. 57. pp. 1-12. ISSN 1756-8935}, doi={10.1186/s13072-018-0229-6}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-254758}, library={UB}, } @article{UBHD-68867355, author={Genenncher, Bianca and Durdevic, Zeljko and Hanna, Katharina and Zinkl, Daniela and Mobin, Mehrpouya Balaghy and Sent{\"u}rk Cetin, Nevcin and Silva, Bruno Da and Legrand, Carine and Carré, Clément and Lyko, Frank and Schaefer, Matthias R.}, title={Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats}, year={2018}, pages={1861-1874}, language={eng}, issn={2211-1247}, volume={22}, number={7}, note={Gesehen am 17.01.2022}, journal={Cell reports}, doi={10.1016/j.celrep.2018.01.061}, } @article{UBHD-68849461, author={Hummel-Eisenbeiß, Johanna and Hascher, Antje and Hals, Petter-Arnt and Sandvold, Marit Liland and M{\"u}ller-Tidow, Carsten and Lyko, Frank and Rius, Maria}, title={The role of human equilibrative nucleoside transporter 1 on the cellular transport of the DNA methyltransferase inhibitors 5-azacytidine and CP-4200 in human leukemia cells}, year={2013}, pages={438-450}, language={eng}, issn={1521-0111}, volume={84}, number={3}, journal={Molecular pharmacology}, doi={10.1124/mol.113.086801}, } @article{UBHD-69131580, author={Koch, Jonas and Neuberger, Manuel and Schmidt-Dengler, Martina and Xu, Jinyun and Coutinho Carneiro, Vitor and Ellinger, J{\"o}rg and Kriegmair, Maximilian and Nuhn, Philipp and Erben, Philipp and Michel, Maurice Stephan and Helm, Mark and Rodríguez Paredes, Manuel and Nientiedt, Malin and Lyko, Frank}, title={Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder}, year={2023}, pages={1-17}, language={eng}, issn={2589-0042}, volume={26}, note={Online verf{\"u}gbar: 11. Juli 2023, Artikelversion: 27. Juli 2023 ; Im Titel ist die Zahl 6 hochgestellt ; Gesehen am 18.10.2023}, journal={iScience}, doi={10.1016/j.isci.2023.107300}, } @article{UBHD-68715645, author={K{\"o}hler, Florian and Bormann, Felix and Raddatz, G{\"u}nter and Gutekunst, Julian and Corless, Samuel and Musch, Tanja and Lonsdorf, Anke Susanne and Erhardt, Sylvia and Lyko, Frank and Rodríguez Paredes, Manuel}, title={Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome}, year={2020}, pages={1-16}, language={eng}, issn={1756-994X}, volume={12}, number={Artikel-ID 46}, note={Gesehen am 23.03.2021}, journal={Genome medicine}, doi={10.1186/s13073-020-00749-y}, } @article{UBHD-68275735, author={Legrand, Carine and Tuorto, Francesca and Hartmann, Mark and Liebers, Reinhard and Jacob, Dominik and Helm, Mark and Lyko, Frank}, title={Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs}, year={2017}, pages={1589-1596}, language={eng}, issn={1549-5469}, volume={27}, number={9}, note={Published in Advance July 6, 2017 ; Gesehen am 29.06.2018}, journal={Genome research}, doi={10.1101/gr.210666.116}, } @article{UBHD-69206877, author={Legrand, Carine and Andriantsoa, Ranja and Lichter, Peter and Raddatz, G{\"u}nter and Lyko, Frank}, title={Time-resolved, integrated analysis of clonally evolving genomes}, edition={Version 2}, year={2023}, pages={1-19}, language={eng}, issn={1553-7404}, volume={19}, note={Gesehen am 23.04.2024}, journal={PLoS Genetics}, doi={10.1371/journal.pgen.1011085}, } @article{UBHD-68320592, author={Linhart, Heinz and Bormann, Felix and Hutter, Barbara and Lyko, Frank}, title={Genetic and epigenetic profiling of a solitary Peutz-Jeghers colon polyp}, year={2017}, pages={9 S.}, language={eng}, issn={2373-2873}, volume={3}, note={Gesehen am 24.10.2018}, journal={Cold Spring Harbor molecular case studies}, doi={10.1101/mcs.a001610}, } @article{UBHD-68320602, author={Lyko, Frank}, title={The DNA methyltransferase family}, subtitle={a versatile toolkit for epigenetic regulation}, year={2018}, pages={81-92}, language={eng}, issn={1471-0064}, volume={19}, number={2}, note={Published online: 16 October 2017 ; Gesehen am 24.10.2018}, journal={Nature reviews}, doi={10.1038/nrg.2017.80}, } @book{UBHD-9823452, author={Lyko, Frank}, title={Identifikation und Charakterisierung von Silencingelementen in cis-regulatorischen Regionen gepr{\"a}gter S{\"a}ugergene mit Hilfe transgener Drosophila melanogaster}, year={1998}, pages={78 Bl.}, language={ger}, school={Heidelberg, Univ., Diss., 1998}, library={UB [Signatur: 98 U 652]}, } @article{UBHD-68320596, author={Lyko, Frank}, title={The marbled crayfish (Decapoda: Cambaridae) represents an independent new species}, year={2017}, pages={544-552}, language={eng}, issn={1175-5334}, volume={4363}, number={4}, note={Gesehen am 24.10.2018}, journal={Zootaxa}, doi={10.11646/zootaxa.4363.4.6}, } @article{UBHD-68867361, author={Maiakovska, Olena and Andriantsoa, Ranja and T{\"o}nges, Sina and Legrand, Carine and Gutekunst, Julian and Hanna, Katharina and Pârvulescu, Lucian and Novitsky, Roman and Weiperth, András and Sciberras, Arnold and Deidun, Alan and Ercoli, Fabio and Kouba, Antonin and Lyko, Frank}, title={Genome analysis of the monoclonal marbled crayfish reveals genetic separation over a short evolutionary timescale}, year={2021}, pages={1-7}, language={eng}, issn={2399-3642}, volume={4}, number={Artikel-ID 74}, note={Gesehen am 17.01.2022}, journal={Communications biology}, doi={10.1038/s42003-020-01588-8}, } @article{UBHD-69072477, author={Motorin, Yuri and Lyko, Frank and Helm, Mark}, title={5-methylcytosine in RNA}, subtitle={detection, enzymatic formation and biological functions}, year={2010}, pages={1415-1430}, language={eng}, issn={1362-4962}, volume={38}, number={5}, note={Erstmals am 08. Dezember 2009 online ver{\"o}ffentlicht ; Gesehen am 05.05.2023}, journal={Nucleic acids research}, doi={10.1093/nar/gkp1117}, } @article{UBHD-68867357, author={M{\"u}ller, Martin and Samel-Pommerencke, Anke and Legrand, Carine and Tuorto, Francesca and Lyko, Frank and Ehrenhofer-Murray, Ann Elizabeth}, title={Division of labour}, subtitle={tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast}, year={2019}, pages={249-256}, language={eng}, issn={1555-8584}, volume={16}, number={3}, note={Gesehen am 17.01.2022}, journal={RNA biology}, doi={10.1080/15476286.2019.1568819}, } @article{UBHD-68867358, author={M{\"u}ller, Martin and Legrand, Carine and Tuorto, Francesca and Kelly, Vincent P. and Atlasi, Yaser and Lyko, Frank and Ehrenhofer-Murray, Ann Elizabeth}, title={Queuine links translational control in eukaryotes to a micronutrient from bacteria}, year={2019}, pages={3711-3727}, language={eng}, issn={1362-4962}, volume={47}, number={7}, note={Ver{\"o}ffentlicht am 1. Februar 2019 ; Gesehen am 17.01.2022}, journal={Nucleic acids research}, doi={10.1093/nar/gkz063}, } @article{UBHD-68320587, author={Peng, Yanxian and Lyko, Frank}, editor={Bocker, Michael}, title={Human fibroblast matrices bio-assembled under macromolecular crowding support stable propagation of human embryonic stem cells}, year={2012}, pages={e74-e86}, language={eng}, issn={1932-7005}, volume={6}, number={10}, note={First published: 03 July 2012 ; Gesehen am 24.10.2018}, journal={Journal of tissue engineering and regenerative medicine}, doi={10.1002/term.1560}, } @article{UBHD-68819232, author={Raddatz, G{\"u}nter and Hagemann, Sabine and Aran, Dvir and S{\"o}hle, J{\"o}rn and Kulkarni, Pranav P. and Kaderali, Lars and Hellman, Asaf and Winnefeld, Marc and Lyko, Frank}, title={Aging is associated with highly defined epigenetic changes in the human epidermis}, year={2013}, pages={1-12}, language={eng}, issn={1756-8935}, volume={6}, note={Gesehen am 13.12.2021}, journal={Epigenetics & chromatin}, doi={10.1186/1756-8935-6-36}, } @article{UBHD-68864202, author={Raddatz, G{\"u}nter and Guzzardo, Paloma M. and Olova, Nelly and Fantappié, Marcelo Rosado and Rampp, Markus and Schaefer, Matthias R. and Reik, Wolf and Hannon, Gregory J. and Lyko, Frank}, title={Dnmt2-dependent methylomes lack defined DNA methylation patterns}, year={2013}, pages={8627-8631}, language={eng}, issn={1091-6490}, volume={110}, number={21}, note={Gesehen am 11.01.2022}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.1306723110}, } @article{UBHD-68319603, author={Raddatz, G{\"u}nter and Bender, Sebastian and Lyko, Frank}, title={Dnmt3a protects active chromosome domains against cancer-associated hypomethylation}, year={2012}, pages={11 S.}, language={eng}, issn={1553-7404}, volume={8}, number={12}, note={Gesehen am 22.10.2018}, journal={PLoS Genetics}, doi={10.1371/journal.pgen.1003146}, } @article{UBHD-68563945, author={Rodríguez Paredes, Manuel and Lucena Porcel, Carlota and Feuerbach, Lars and Brors, Benedikt and Herpel, Esther and Hofmann, Thomas G. and Lyko, Frank}, title={Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin}, year={2018}, pages={1-9}, language={eng}, issn={2041-1723}, volume={9}, number={Artikel-ID 577}, note={Gesehen am 14.04.2020}, journal={Nature Communications}, doi={10.1038/s41467-018-03025-1}, } @article{UBHD-69108386, author={Schaefer, Matthias R. and Pollex, Tim and Hanna, Katharina and Tuorto, Francesca and Meusburger, Madeleine and Helm, Mark and Lyko, Frank}, title={RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage}, year={2010}, pages={1590-1595}, language={eng}, issn={1549-5477}, volume={24}, number={15}, note={Gesehen am 10.08.2023}, journal={Genes & development}, doi={10.1101/gad.586710}, } @article{UBHD-69130726, author={Sch{\"u}tz, Sabrina and Solé-Boldo, Llorenç and Lucena Porcel, Carlota and Hoffmann, Jochen and Brobeil, Alexander and Lonsdorf, Anke Susanne and Rodríguez Paredes, Manuel and Lyko, Frank}, title={Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma}, year={2023}, pages={1-14}, language={eng}, issn={2041-1723}, volume={14}, number={Artikel-ID 5413}, note={Ver{\"o}ffentlicht: 05. September 2023 ; Gesehen am 17.10.2023}, journal={Nature Communications}, doi={10.1038/s41467-023-41141-9}, } @book{UBHD-66562211, editor={Lyko, Frank and Martoglio, Bruno and Jungnickel, Berit and Rapoport, Tom A. and Dobberstein, Bernhard}, title={Signal sequence processing in rough microsomes}, publisher={Universit{\"a}tsbibliothek der Universit{\"a}t Heidelberg}, address={Heidelberg}, year={1995}, pages={Online-Ressource}, language={eng}, note={Wissenschaftl. Aufsatz in: The Journal of Biological Chemistry 1995, 270 (34): 19873-19878 ; Online publiziert: 2008}, url={http://www.ub.uni-heidelberg.de/archiv/8560}, library={UB}, } @article{UBHD-68987842, author={Solé-Boldo, Llorenç and Raddatz, G{\"u}nter and Gutekunst, Julian and Gilliam, Oliver and Bormann, Felix and Liberio, Michelle S and Hasche, Daniel and Antonopoulos, Wiebke and Mallm, Jan-Philipp and Lonsdorf, Anke Susanne and Rodríguez Paredes, Manuel and Lyko, Frank}, title={Differentiation-related epigenomic changes define clinically distinct keratinocyte cancer subclasses}, year={2022}, pages={22 S.}, language={eng}, issn={1744-4292}, volume={18}, note={Gesehen am 22.11.2022}, journal={Molecular systems biology}, doi={10.15252/msb.202211073}, } @article{UBHD-68398917, author={Tuorto, Francesca and Legrand, Carine and Cirzi, Cansu and Federico, Giuseppina and Liebers, Reinhard and M{\"u}ller, Martin and Ehrenhofer-Murray, Ann Elizabeth and Dittmar, Gunnar and Gr{\"o}ne, Hermann-Josef and Lyko, Frank}, title={Queuosine‐modified tRNAs confer nutritional control of protein translation}, year={2018}, pages={14 S.}, language={eng}, issn={1460-2075}, volume={37(2018}, note={Gesehen am 14.06.2019}, journal={The EMBO journal}, doi={10.15252/embj.201899777}, } @article{UBHD-68067264, author={Tuorto, Francesca and Herbst, Friederike and Alerasool, Nader and Bender, Sebastian and Reitter, Sonja and Liebers, Reinhard and Stoecklin, Georg and Glimm, Hanno and Lyko, Frank}, title={The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis}, year={2015}, pages={2350-2362}, language={eng}, issn={1460-2075}, volume={34}, number={18}, note={Gesehen am 21.12.2016}, journal={The EMBO journal}, doi={10.15252/embj.201591382}, } @article{UBHD-68626362, author={Wiehle, Laura and Lyko, Frank and Breiling, Achim}, title={Tet1 and Tet2 protect DNA methylation canyons against hypermethylation}, year={2016}, pages={452-461}, language={eng}, issn={1098-5549}, volume={36}, number={3}, note={Gesehen am 19.08.2020}, journal={Molecular and cellular biology}, doi={10.1128/MCB.00587-15}, }