@article{UBHD-68573649, author={Allg{\"a}uer, Michael and Budczies, Jan and Christopoulos, Petros and Endris, Volker and Lier, Amelie and Rempel, Eugen and Volckmar, Anna-Lena and Kirchner, Martina and Winterfeld, Moritz von and Leichsenring, Jonas and Neumann, Olaf and Fr{\"o}hling, Stefan and Penzel, Roland and Thomas, Michael and Schirmacher, Peter and Stenzinger, Albrecht}, title={Implementing tumor mutational burden (TMB) analysis in routine diagnostics}, subtitle={a primer for molecular pathologists and clinicians}, year={2018}, pages={703-715}, language={eng}, issn={2226-4477}, volume={7}, number={6}, note={Gesehen am 05.05.2020}, journal={Translational Lung Cancer Research}, doi={10.21037/tlcr.2018.08.14}, } @article{UBHD-68443711, author={Blume, Rachel and Rempel, Eugen and Manta, Linda and Saeed, Borhan R. and Wang, Wenwen and Raffel, Simon and Ermakova, Olga and Eckstein, Volker and Trumpp, Andreas and Ho, Anthony Dick and Lutz, Christoph}, title={The molecular signature of AML with increased ALDH activity suggests a stem cell origin}, year={2018}, pages={2201-2210}, language={eng}, issn={1029-2403}, volume={59}, number={9}, note={Gesehen am 22.10.2019}, journal={Leukemia and lymphoma}, doi={10.1080/10428194.2017.1422862}, } @article{UBHD-68360071, author={Buchhalter, Ivo and Rempel, Eugen and Endris, Volker and Allg{\"a}uer, Michael and Neumann, Olaf and Volckmar, Anna-Lena and Kirchner, Martina and Leichsenring, Jonas and Lier, Amelie and Winterfeld, Moritz von and Penzel, Roland and Christopoulos, Petros and Thomas, Michael and Fr{\"o}hling, Stefan and Schirmacher, Peter and Budczies, Jan and Stenzinger, Albrecht}, title={Size matters}, subtitle={Dissecting key parameters for panel-based tumor mutational burden analysis}, year={2019}, pages={848-858}, language={eng}, issn={1097-0215}, volume={144}, number={4}, note={Online 21 September 2018 ; Gesehen am 19.02.2019}, journal={International journal of cancer}, doi={10.1002/ijc.31878}, } @article{UBHD-68468671, author={Budczies, Jan and Allg{\"a}uer, Michael and Rempel, Eugen and Christopoulos, Petros and Kazdal, Daniel and Endris, Volker and Thomas, Michael and Fr{\"o}hling, Stefan and Schirmacher, Peter and Stenzinger, Albrecht}, title={Optimizing panel-based tumor mutational burden (TMB) measurement}, year={2019}, pages={1496-1506}, language={eng}, issn={1569-8041}, volume={30}, number={9}, note={Gesehen am 17.12.2019}, journal={Annals of oncology}, doi={10.1093/annonc/mdz205}, } @article{UBHD-68578220, author={Budczies, Jan and Kazdal, Daniel and Allg{\"a}uer, Michael and Christopoulos, Petros and Rempel, Eugen and Pfarr, Nicole and Weichert, Wilko and Fr{\"o}hling, Stefan and Thomas, Michael and Peters, Solange and Endris, Volker and Schirmacher, Peter and Stenzinger, Albrecht}, title={Quantifying potential confounders of panel-based tumor mutational burden (TMB) measurement}, year={2020}, pages={114-119}, language={eng}, issn={1872-8332}, volume={142}, note={Gesehen am 15.05.2020}, journal={Lung cancer}, doi={10.1016/j.lungcan.2020.01.019}, } @article{UBHD-68392483, author={Endris, Volker and Allg{\"a}uer, Michael and Rempel, Eugen and Lier, Amelie and Volckmar, Anna-Lena and Winterfeld, Moritz von and Leichsenring, Jonas and Neumann, Olaf and Penzel, Roland and Glimm, Hanno and Fr{\"o}hling, Stefan and Winter, Hauke and Herth, Felix and Thomas, Michael and Schirmacher, Peter and Budczies, Jan and Stenzinger, Albrecht}, title={Measurement of tumor mutational burden (TMB) in routine molecular diagnostics}, subtitle={in silico and real-life analysis of three larger gene panels}, year={2019}, pages={2303-2312}, language={eng}, issn={1097-0215}, volume={144}, number={9}, note={First published: 17 November 2018 ; Gesehen am 23.05.2019}, journal={International journal of cancer}, doi={10.1002/ijc.32002}, } @article{UBHD-68264335, author={Himmels, Patricia and Paredes Ugarte, Isidora B. and Adler, Heike and Karakatsani, Andromachi and Luck, Robert and Marti, Hugo and Ermakova, Olga and Rempel, Eugen and Ruiz de Almodóvar, Carmen}, title={Motor neurons control blood vessel patterning in the developing spinal cord}, year={2017}, pages={16 S.}, language={eng}, issn={2041-1723}, volume={8(2017) Article number 14583}, number={16 Seiten}, note={Published 6 Mar 2017 ; Gesehen am 22.06.2018}, journal={Nature Communications}, doi={10.1038/ncomms14583}, } @article{UBHD-68869061, author={Kazdal, Daniel and Rempel, Eugen and Oliveira, Cristiano and Allg{\"a}uer, Michael and Harms, Alexander and Singer, Kerstin and Kohlwes, Elke and Ormanns, Steffen and Fink, Ludger and Kriegsmann, J{\"o}rg and Leichsenring, Michael and Kriegsmann, Katharina and St{\"o}gbauer, Fabian and Tavernar, Luca and Leichsenring, Jonas and Volckmar, Anna-Lena and Longuespée, Rémi and Winter, Hauke and Eichhorn, Martin E. and Heußel, Claus Peter and Herth, Felix and Christopoulos, Petros and Reck, Martin and Muley, Thomas and Weichert, Wilko and Budczies, Jan and Thomas, Michael and Peters, Solange and Warth, Arne and Schirmacher, Peter and Stenzinger, Albrecht and Kriegsmann, Mark}, title={Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma}, year={2021}, pages={1-15}, language={eng}, issn={2226-4477}, volume={10}, number={Artikel-ID 4}, note={Gesehen am 20.01.2021}, journal={Translational Lung Cancer Research}, doi={10.21037/tlcr-20-1168}, } @article{UBHD-68469264, author={Kazdal, Daniel and Endris, Volker and Allg{\"a}uer, Michael and Kriegsmann, Mark and Leichsenring, Jonas and Volckmar, Anna-Lena and Harms, Alexander and Kirchner, Martina and Kriegsmann, Katharina and Neumann, Olaf and Brandt, Regine and Talla, Suranand Babu and Rempel, Eugen and Pl{\"o}ger, Carolin and Winterfeld, Moritz von and Christopoulos, Petros and Bischoff, Helge and Meister, Michael and Muley, Thomas and Herth, Felix and Penzel, Roland and Warth, Arne and Winter, Hauke and Fr{\"o}hling, Stefan and Thomas, Michael and Schirmacher, Peter and Budczies, Jan and Stenzinger, Albrecht}, title={Spatial and temporal heterogeneity of panel-based tumor mutational burden in pulmonary adenocarcinoma}, subtitle={separating biology from technical artifacts}, year={2019}, pages={1935-1947}, language={eng}, issn={1556-1380}, volume={14}, number={11}, note={Gesehen am 18.12.2019}, journal={Journal of thoracic oncology}, doi={10.1016/j.jtho.2019.07.006}, } @article{UBHD-68440744, author={Kirchner, Martina and Neumann, Olaf and Volckmar, Anna-Lena and St{\"o}gbauer, Fabian and Allg{\"a}uer, Michael and Kazdal, Daniel and Budczies, Jan and Rempel, Eugen and Brandt, Regine and Talla, Suranand Babu and Winterfeld, Moritz von and Leichsenring, Jonas and Bochtler, Tilmann and Kr{\"a}mer, Alwin and Springfeld, Christoph and Schirmacher, Peter and Penzel, Roland and Endris, Volker and Stenzinger, Albrecht}, title={RNA-based detection of gene fusions in formalin-fixed and paraffin-embedded solid cancer samples}, year={2019}, pages={17 S.}, language={eng}, issn={2072-6694}, volume={11(2019}, note={Gesehen am 15.10.2019}, journal={Cancers}, doi={10.3390/cancers11091309}, url={https://doi.org/10.3390/cancers11091309}, library={UB}, } @article{UBHD-68447463, author={Leichsenring, Jonas and Horak, Peter and Heining, Christoph and Christopoulos, Petros and Volckmar, Anna-Lena and Neumann, Olaf and Kirchner, Martina and Budczies, Jan and Heilig, Christoph E. and Kazdal, Daniel and Allg{\"a}uer, Michael and Harms, Alexander and Rempel, Eugen and Thomas, Michael and Longerich, Thomas and Schirmacher, Peter and Penzel, Roland and Endris, Volker and Fr{\"o}hling, Stefan and Stenzinger, Albrecht}, title={Variant classification in precision oncology}, year={2019}, pages={2996-3010}, language={eng}, issn={1097-0215}, volume={145}, number={11}, note={Gesehen am 29.10.2019}, journal={International journal of cancer}, doi={10.1002/ijc.32358}, } @article{UBHD-68413214, author={Leichsenring, Jonas and Kazdal, Daniel and Pl{\"o}ger, Carolin and Allg{\"a}uer, Michael and Endris, Volker and Volckmar, Anna-Lena and Neumann, Olaf and Kirchner, Matthias and Penzel, Roland and Rempel, Eugen and Budczies, Jan and Schirmacher, Peter and Fr{\"o}hling, Stefan and Stenzinger, Albrecht}, title={Von der Paneldiagnostik zu umfassenden genomischen Analysen}, year={2019}, pages={235-242}, language={ger}, issn={1432-1963}, volume={40}, number={3}, note={Gesehen am 29.07.2019}, journal={Der Pathologe}, doi={10.1007/s00292-019-0608-1}, } @article{UBHD-68444288, author={Longerich, Thomas and Endris, Volker and Neumann, Olaf and Rempel, Eugen and Kirchner, Martina and Abadi, Zahra and Kriegsmann, Mark and Weiss, Karl Heinz and Breuhahn, Kai and Mehrabi, Arianeb and Weber, Tim and Fr{\"o}hling, Stefan and Pellegrino, Rossella and Budczies, Jan and Schirmacher, Peter and Stenzinger, Albrecht}, title={RSPO2 gene rearrangement}, subtitle={a powerful driver of β-catenin activation in liver tumours}, year={2019}, pages={1287-1296}, language={eng}, issn={1468-3288}, volume={68}, number={7}, note={Published online first 2 February 2019 ; Gesehen am 23.10.2019}, journal={Gut}, doi={10.1136/gutjnl-2018-317632}, } @article{UBHD-68306454, author={Marchan, Rosemarie and Rempel, Eugen}, title={Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma}, year={2017}, pages={4589-4601}, language={eng}, issn={1538-7445}, volume={77}, number={17}, note={Gesehen am 20.09.2018}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-16-2065}, } @article{UBHD-68119334, author={Pfeiffer, Anne and Janocha, Denis and Dong, Yihan and Medzihradszky, Anna and Daum, Gabor and Suzaki, Takuya and Forner, Joachim and Rempel, Eugen and Wirtz, Markus and Hell, R{\"u}diger and Lohmann, Jan U.}, title={Integration of light and metabolic signals for stem cell activation at the shoot apical meristem}, year={2016}, pages={21 S.}, language={eng}, issn={2050-084X}, volume={5(2016) Artikel-Nr. e17023}, number={21 Seiten}, note={Gesehen am 15.05.2017}, journal={eLife}, doi={10.7554/eLife.17023}, } @article{UBHD-68943370, author={Rempel, Eugen and Kluck, Klaus and Beck, Susanne and Ourailidis, Iordanis and Kazdal, Daniel and Neumann, Olaf and Volckmar, Anna-Lena and Kirchner, Martina and Goldschmid, Hannah and Pfarr, N. and Weichert, Wilko and H{\"u}bschmann, Daniel and Fr{\"o}hling, Stefan and Sutter, Christian and Schaaf, Christian P. and Schirmacher, Peter and Endris, Volker and Stenzinger, Albrecht and Budczies, Jan}, title={Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD)}, year={2022}, pages={1-13}, language={eng}, issn={2397-768X}, volume={6}, number={Artikel-ID 36}, note={Gesehen am 18.07.2022}, journal={npj precision oncology}, doi={10.1038/s41698-022-00276-6}, url={https://doi.org/10.1038/s41698-022-00276-6}, library={UB}, } @article{UBHD-68588479, author={Rempel, Eugen and Hoelting, Lisa and Waldmann, Tanja and Balmer, Nina V. and Schildknecht, Stefan and Grinberg, Marianna and Das Gaspar, John Antony and Shinde, Vaibhav and St{\"o}ber, Regina and Marchan, Rosemarie and Thriel, Christoph van and Liebing, Julia and Meisig, Johannes and Bl{\"u}thgen, Nils and Sachinidis, Agapios and Rahnenf{\"u}hrer, J{\"o}rg and Hengstler, Jan G. and Leist, Marcel}, title={A transcriptome-based classifier to identify developmental toxicants by stem cell testing}, subtitle={design, validation and optimization for histone deacetylase inhibitors}, year={2015}, pages={1599-1618}, language={eng}, issn={1432-0738}, volume={89}, number={9}, note={Gesehen am 18.06.2020}, journal={Archives of toxicology}, doi={10.1007/s00204-015-1573-y}, } @article{UBHD-68489583, author={Rinaldetti, Sébastien and Rempel, Eugen and Worst, Thomas and Steidler, Annette and Erben, Philipp}, title={Subclassification, survival prediction and drug target analyses of chemotherapy-nai͏̈ve muscle-invasive bladder cancer with a molecular screening}, year={2018}, pages={25935-25945}, language={eng}, issn={1949-2553}, volume={9}, number={40}, note={Gesehen am 17.02.2020}, journal={OncoTarget}, doi={10.18632/oncotarget.25407}, } @article{UBHD-68685002, author={Rinaldetti, Sébastien and Worst, Thomas and Rempel, Eugen and Kriegmair, Maximilian and Hartmann, Arndt and Porubsky, Stefan and Bolenz, Christian and Erben, Philipp}, title={Subtype specific expression and survival prediction of pivotal lncRNAs in muscle invasive bladder cancer}, year={2020}, pages={9 S.}, language={eng}, issn={2045-2322}, volume={10(2020) Artikel-Nummer 20472}, number={9 Seiten}, note={Gesehen am 28.01.2021}, journal={Scientific reports}, doi={10.1038/s41598-020-77252-2}, url={https://doi.org/10.1038/s41598-020-77252-2}, library={UB}, } @article{UBHD-68292489, author={Shinde, Vaibhav and Rempel, Eugen}, title={Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development}, subtitle={introduction of the STOP-Toxukn and STOP-Toxukk tests}, year={2017}, pages={839-864}, language={eng}, issn={1432-0738}, volume={91}, number={2}, note={Published online: 17 May 2016 ; Im Titel sind "ukn" und "ukk" tiefer gestellt ; Gesehen am 06.08.2018}, journal={Archives of toxicology}, doi={10.1007/s00204-016-1741-8}, } @article{UBHD-68496134, author={Stenzinger, Albrecht and Endris, Volker and Budczies, Jan and Merkelbach-Bruse, Sabine and Kazdal, Daniel and Dietmaier, Wolfgang and Pfarr, Nicole and Siebolts, Udo and Hummel, Michael and Herold, Sylvia and Andreas, Johanna and Zoche, Martin and T{\"o}gel, Lars and Rempel, Eugen and Maas, J{\"o}rg and Merino, Diana and Stewart, Mark and Plath, Karim and Schlesner, Matthias and Glimm, Hanno and Fr{\"o}hling, Stefan and Allen, Jeff and Horst, David and Baretton, Gustavo and Wickenhauser, Claudia and Tiemann, Markus and Evert, Matthias and Moch, Holger and Kirchner, Thomas and B{\"u}ttner, Reinhard and Schirmacher, Peter and Jung, Andreas and Haller, Florian and Weichert, Wilko and Dietel, Manfred}, title={Harmonization and standardization of panel-based tumor mutational burden (TMB) measurement}, subtitle={real-world results and recommendations of the QuIP study}, year={2020}, pages={1177-1189}, language={eng}, issn={1556-1380}, volume={15}, number={7}, note={Gesehen am 04.03.2020}, journal={Journal of thoracic oncology}, doi={10.1016/j.jtho.2020.01.023}, } @article{UBHD-68863944, author={Talla, Suranand Babu and Rempel, Eugen and Endris, Volker and Jenzer, Maximilian and Allg{\"a}uer, Michael and Schwab, Constantin and Kazdal, Daniel and St{\"o}gbauer, Fabian and Volckmar, Anna-Lena and Kocsmar, Ildiko and Neumann, Olaf and Schirmacher, Peter and Zsch{\"a}bitz, Stefanie and Duensing, Stefan and Budczies, Jan and Stenzinger, Albrecht and Kirchner, Martina}, title={Immuno-oncology gene expression profiling of formalin-fixed and paraffin-embedded clear cell renal cell carcinoma}, subtitle={Performance comparison of the NanoString nCounter technology with targeted RNA sequencing}, year={2020}, pages={406-416}, language={eng}, issn={1098-2264}, volume={59}, number={7}, note={First published: 25 March 2020 ; Gesehen am 10.01.2022}, journal={Genes, chromosomes & cancer}, doi={10.1002/gcc.22843}, url={https://doi.org/10.1002/gcc.22843}, library={UB}, } @article{UBHD-68387453, author={Tamirisa, Srividya and Papagiannouli, Fani and Rempel, Eugen and Ermakova, Olga and Trost, Nils and Zhou, Jun and Ruhland, Naima and Boutros, Michael and Lohmann, Jan U. and Lohmann, Ingrid}, title={Decoding the regulatory logic of the Drosophila male stem cell system}, year={2018}, pages={3072-3086}, language={eng}, issn={2211-1247}, volume={24}, number={11}, note={Gesehen am 07.05.2019}, journal={Cell reports}, doi={10.1016/j.celrep.2018.08.013}, } @article{UBHD-68909992, author={Thomann, Stefan and Weiler, Sofia Maria Elisabeth and Marquard, Simone and Rose, Fabian and Ball, Claudia R. and Tóth, Marcell and Wei, Teng and Sticht, Carsten and Fritzsche, Sarah and R{\"o}ssler, Stephanie and Torre, Carolina de la and Ryschich, Eduard and Ermakova, Olga and Mogler, Carolin and Kazdal, Daniel and Gretz, Norbert and Glimm, Hanno and Rempel, Eugen and Schirmacher, Peter and Breuhahn, Kai}, title={YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis}, year={2020}, pages={5502-5514}, language={eng}, issn={1538-7445}, volume={80}, number={24}, note={Gesehen am 23.04.2022}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-20-0242}, } @article{UBHD-68395247, author={Trost, Nils and Rempel, Eugen and Ermakova, Olga and Tamirisa, Srividya and Pârcălăbescu, Letiția and Lohmann, Jan U. and Lohmann, Ingrid}, title={WEADE}, subtitle={a workflow for enrichment analysis and data exploration}, year={2018}, pages={10 S.}, language={eng}, issn={1932-6203}, volume={13(2018}, note={Gesehen am 04.06.2019}, journal={PLOS ONE}, doi={10.1371/journal.pone.0204016}, } @article{UBHD-68359655, author={Volckmar, Anna-Lena and Leichsenring, Jonas and Kirchner, Martina and Christopoulos, Petros and Neumann, Olaf and Budczies, Jan and Oliveira, Cristiano and Rempel, Eugen and Buchhalter, Ivo and Brandt, Regine and Allg{\"a}uer, Michael and Talla, Suranand Babu and Winterfeld, Moritz von and Herpel, Esther and Goeppert, Benjamin and Lier, Amelie and Winter, Hauke and Fr{\"o}hling, Stefan and Heußel, Claus Peter and Herth, Felix and Lasitschka, Felix and Schirmacher, Peter and Thomas, Michael and Endris, Volker and Penzel, Roland and Stenzinger, Albrecht}, title={Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics}, subtitle={analysis of the first 3000 Heidelberg cases}, year={2019}, pages={649-661}, language={eng}, issn={1097-0215}, volume={145}, number={3}, note={Accepted manuscript online: 17 January 2019 ; Gesehen am 18.02.2019}, journal={International journal of cancer}, doi={10.1002/ijc.32133}, } @article{UBHD-68741506, author={Volckmar, Anna-Lena and Christopoulos, Petros and Kirchner, Martina and Allg{\"a}uer, Michael and Neumann, Olaf and Budczies, Jan and Rempel, Eugen and Horak, Peter and Glade, Julia and Goldschmid, Hannah and Şeker-Cin, Huriye and Brandt, Regine and Kriegsmann, Mark and Leichsenring, Jonas and Winter, Hauke and Faehling, Martin and Fischer, J{\"u}rgen and Heußel, Claus Peter and Herth, Felix and Brummer, Tilman and Fr{\"o}hling, Stefan and Schirmacher, Peter and Thomas, Michael and Endris, Volker and Penzel, Roland and Kazdal, Daniel and Bochtler, Tilmann and Stenzinger, Albrecht}, title={Targeting rare and non-canonical driver variants in NSCLC}, subtitle={an uncharted clinical field}, year={2021}, pages={131-141}, language={eng}, issn={1872-8332}, volume={154(2021) vom: Apr.}, note={Gesehen am 27.05.2021}, journal={Lung cancer}, doi={10.1016/j.lungcan.2021.02.022}, }