@article{UBHD-68797201, author={Alfarouk, Khalid and Alqahtani, Saad S. and Alshahrani, Saeed and Morgenstern, Jakob and Supuran, Claudiu T. and Reshkin, Stephan J.}, title={The possible role of methylglyoxal metabolism in cancer}, year={2021}, pages={2010-2015}, language={eng}, issn={1475-6374}, volume={36}, number={1}, note={Gesehen am 05.11.2021}, journal={Journal of enzyme inhibition and medicinal chemistry}, doi={10.1080/14756366.2021.1972994}, } @article{UBHD-68707540, author={Chen, Jessy and Fleming, Thomas and Katz, Sylvia and Dewenter, Matthias and Hofmann, Kai and Saadatmand, Ali R. and Kronlage, Mariya and Werner, Moritz P. and Pokrandt, Bianca and Schreiter, Friederike and Lin, Jihong and Katz, Daniel and Morgenstern, Jakob and Elwakiel, Ahmed and Sinn, Peter and Gr{\"o}ne, Hermann-Josef and Hammes, Hans-Peter and Nawroth, Peter Paul and Isermann, Berend and Sticht, Carsten and Br{\"u}gger, Britta and Katus, Hugo and Hagenmueller, Marco and Backs, Johannes}, title={CaM kinase II-δ is required for diabetic hyperglycemia and retinopathy but not nephropathy}, year={2021}, pages={616-626}, language={eng}, issn={1939-327X}, volume={70}, number={2}, note={Epub 2020 Nov 25 ; Gesehen am 05.03.2021}, journal={Diabetes}, doi={10.2337/db19-0659}, } @article{UBHD-68963730, author={Garcia Cortizo, Fabiola and Pfaff, Daniel and Wirth, Angela and Schlotterer, Andrea and Medert, Rebekka and Morgenstern, Jakob and Weber, Tobias and Hammes, Hans-Peter and Fleming, Thomas and Nawroth, Peter Paul and Freichel, Marc and Teleman, Aurelio A.}, title={The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136}, year={2022}, pages={1-11}, language={eng}, issn={2212-8778}, volume={55(2022) vom: Jan.}, number={Artikel-ID 101406}, note={Available online 25 November 2021 ; Gesehen am 13.09.2022}, journal={Molecular metabolism}, doi={10.1016/j.molmet.2021.101406}, } @article{UBHD-68659354, author={Jende, Johann and Kender, Zoltán and Rother, Christian and Alvarez-Ramos, Lucia and Gr{\"o}ner, Jan and Pham, Mirko and Morgenstern, Jakob and Oikonomou, Dimitrios and Hahn, Artur and J{\"u}rchott, Alexander and Hayes, Jennifer and Heiland, Sabine and Kopf, Stefan and Nawroth, Peter Paul and Bendszus, Martin and Kurz, Felix T.}, title={Diabetic polyneuropathy is associated with pathomorphological changes in human dorsal root ganglia}, subtitle={a study using 3T MR neurography}, year={2020}, language={eng}, issn={1662-453X}, volume={14(2020) Artikel-Nummer 570744}, number={9 Seiten}, note={Gesehen am 10.11.2020}, journal={Frontiers in neuroscience}, doi={10.3389/fnins.2020.570744}, url={https://doi.org/10.3389/fnins.2020.570744}, library={UB}, } @article{UBHD-68879091, author={Jende, Johann and Kender, Zoltán and Morgenstern, Jakob and Renn, Pascal and Mooshage, Christoph and J{\"u}rchott, Alexander and Kopf, Stefan and Nawroth, Peter Paul and Bendszus, Martin and Kurz, Felix T.}, title={Fractional anisotropy and troponin T parallel structural nerve damage at the upper extremities in a group of patients with prediabetes and type 2 diabetes}, subtitle={a study using 3T magnetic resonance neurography}, year={2022}, pages={1-8}, language={eng}, issn={1662-453X}, volume={15}, number={Artikel-ID 741494}, note={Gesehen am 16.02.2022}, journal={Frontiers in neuroscience}, doi={10.3389/fnins.2021.741494}, url={https://doi.org/10.3389/fnins.2021.741494}, library={UB}, } @article{UBHD-68581705, author={Jende, Johann and Gr{\"o}ner, Jan and Kender, Zoltán and Hahn, Artur and Morgenstern, Jakob and Heiland, Sabine and Nawroth, Peter Paul and Bendszus, Martin and Kopf, Stefan and Kurz, Felix T.}, title={Troponin T parallels structural nerve damage in type 2 diabetes}, subtitle={a cross-sectional study using magnetic resonance neurography}, year={2020}, pages={713-723}, language={eng}, issn={1939-327X}, volume={69}, number={4}, note={Gesehen am 28.05.2020}, journal={Diabetes}, doi={10.2337/db19-1094}, } @article{UBHD-68701997, author={Li, Xiaogang and Schm{\"o}hl, Felix and Qi, Haozhe and Bennewitz, Katrin and Tabler, Christoph Tobias and Poschet, Gernot and Hell, R{\"u}diger and Volk, Nadine and Poth, Tanja and Haußer-Siller, Ingrid and Morgenstern, Jakob and Fleming, Thomas and Nawroth, Peter Paul and Kroll, Jens}, title={Regulation of gluconeogenesis by Aldo-keto-reductase 1a1b in zebrafish}, year={2020}, pages={29 S.}, language={eng}, issn={2589-0042}, volume={23(2020}, note={Gesehen am 22.02.2021}, journal={iScience}, doi={10.1016/j.isci.2020.101763}, } @article{UBHD-68451049, author={Lodd, Elisabeth and Wiggenhauser, Lucas and Morgenstern, Jakob and Fleming, Thomas and Poschet, Gernot and B{\"u}ttner, Michael and Tabler, Christoph Tobias and Wohlfart, David Philipp and Nawroth, Peter Paul and Kroll, Jens}, title={The combination of loss of glyoxalase1 and obesity results in hyperglycemia}, year={2019}, language={eng}, issn={2379-3708}, volume={4(2019}, note={Published June 20, 2019 ; Gesehen am 06.11.2019}, journal={JCI insight}, doi={10.1172/jci.insight.126154}, } @article{UBHD-68696609, author={Lou, Bowen and Boger, Mike and Bennewitz, Katrin and Sticht, Carsten and Kopf, Stefan and Morgenstern, Jakob and Fleming, Thomas and Hell, R{\"u}diger and Yuan, Zuyi and Nawroth, Peter Paul and Kroll, Jens}, title={Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans}, year={2020}, pages={16 S.}, language={eng}, issn={2213-2317}, volume={37(2020) Artikel-Nummer 101723}, number={16 Seiten}, note={Gesehen am 08.02.2021}, journal={Redox Biology}, doi={10.1016/j.redox.2020.101723}, } @article{UBHD-68664854, author={Morgenstern, Jakob and Campos Campos, Marta and Nawroth, Peter Paul and Fleming, Thomas}, title={The glyoxalase system}, subtitle={new insights into an ancient metabolism}, year={2020}, pages={15 S.}, language={eng}, issn={2076-3921}, volume={9(2020}, note={Gesehen am 24.11.2020}, journal={Antioxidants}, doi={10.3390/antiox9100939}, } @book{UBHD-68358266, author={Morgenstern, Jakob}, organization={Universit{\"a}t Heidelberg}, title={Importance of alternative enzymatic pathways involved in the detoxification of methylglyoxal in Diabetes}, address={Heidelberg}, year={2017}, pages={78 Bl{\"a}tter}, language={eng}, school={Dissertation, Ruprecht-Karls-Universit{\"a}t Heidelberg, 2018}, library={UB [Signatur: 2019 U 168]}, } @article{UBHD-68251838, author={Morgenstern, Jakob and Fleming, Thomas and Schumacher, Dagmar and Eckstein, Volker and Freichel, Marc and Herzig, Stephan and Nawroth, Peter Paul}, title={Loss of glyoxalase 1 induces compensatory mechanism to achieve dicarbonyl detoxification in mammalian schwann cells}, year={2017}, pages={3224-3238}, language={eng}, issn={1083-351X}, volume={292}, number={8}, note={First Published on December 12, 2016 ; Gesehen am 14.05.2018}, journal={The journal of biological chemistry}, doi={10.1074/jbc.M116.760132}, } @article{UBHD-69102304, author={Morgenstern, Jakob and Gr{\"o}ner, Jan and Jende, Johann and Kurz, Felix T. and Strom, Alexander and G{\"o}pfert, Jens Christian and Kender, Zoltán and Le Marois, Maxime and Brune, Maik and Kuner, Rohini and Herzig, Stephan and Roden, Michael and Ziegler, Dan and Bendszus, Martin and Szendr{\"o}di, Julia and Nawroth, Peter Paul and Kopf, Stefan and Fleming, Thomas}, title={Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy}, year={2021}, pages={2843-2855}, language={eng}, issn={1432-0428}, volume={64}, number={12}, note={Gesehen am 28.07.2023}, journal={Diabetologia}, doi={10.1007/s00125-021-05557-6}, url={https://doi.org/10.1007/s00125-021-05557-6}, library={UB}, } @article{UBHD-68656849, author={Morgenstern, Jakob and Katz, Sylvia and Krebs-Haupenthal, Jutta and Chen, Jessy and Saadatmand, Ali R. and Garcia Cortizo, Fabiola and Zemva, Johanna and Campos Campos, Marta and Teleman, Aurelio A. and Backs, Johannes and Nawroth, Peter Paul and Fleming, Thomas}, title={Phosphorylation of T107 by CamKII[delta] regulates the detoxification efficiency and proteomic integrity of glyoxalase 1}, year={2020}, pages={14 S.}, language={eng}, issn={2211-1247}, volume={32(2020}, note={Im Titel wird delta als griechischer Buchstabe dargestellt ; Gesehen am 03.11.2020}, journal={Cell reports}, doi={10.1016/j.celrep.2020.108160}, } @article{UBHD-68703384, author={Morgenstern, Jakob and Fleming, Thomas and Kliemank, Elisabeth and Brune, Maik and Nawroth, Peter Paul and Fischer, Andreas}, title={Quantification of all-trans retinoic acid by liquid chromatography-tandem mass spectrometry and association with lipid profile in patients with Type 2 diabetes}, year={2021}, pages={1-10}, language={eng}, issn={2218-1989}, volume={11}, note={Gesehen am 24.02.2021}, journal={Metabolites}, doi={10.3390/metabo11010060}, } @article{UBHD-68251830, author={Morgenstern, Jakob and Fleming, Thomas and Kadiyska, Ivelina and Brings, Sebastian and Gr{\"o}ner, Jan and Nawroth, Peter Paul and Hecker, Markus and Brune, Maik}, title={Sensitive mass spectrometric assay for determination of 15-deoxy-Δ12,14-prostaglandin J2 and its application in human plasma samples of patients with diabetes}, year={2018}, pages={521-528}, language={eng}, issn={1618-2650}, volume={410}, number={2}, note={Published online: 16 November 2017 ; Gesehen am 14.05.2018 ; Die Zahlen im Titel 12,14 sind hochgestellt, die 2 ist tiefgestellt}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-017-0748-1}, } @article{UBHD-69166884, author={Qian, Xin and Klatt, Stephan and Bennewitz, Katrin and Wohlfart, David Philipp and Lou, Bowen and Meng, Ye and B{\"u}ttner, Michael and Poschet, Gernot and Morgenstern, Jakob and Fleming, Thomas and Sticht, Carsten and Haußer-Siller, Ingrid and Fleming, Ingrid and Szendr{\"o}di, Julia and Nawroth, Peter Paul and Kroll, Jens}, title={Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease}, year={2024}, pages={1-17}, language={eng}, issn={2198-3844}, volume={11}, note={Online verf{\"u}gbar: 7. Dezember 2023 ; Gesehen am 29.01.2024}, journal={Advanced science}, doi={10.1002/advs.202302325}, } @article{UBHD-68992846, author={Qi, Haozhe and Schm{\"o}hl, Felix and Li, Xiaogang and Qian, Xin and Tabler, Christoph Tobias and Bennewitz, Katrin and Sticht, Carsten and Morgenstern, Jakob and Fleming, Thomas and Volk, Nadine and Haußer-Siller, Ingrid and Heidenreich, Elena and Hell, R{\"u}diger and Nawroth, Peter Paul and Kroll, Jens}, title={Reduced acrolein detoxification in akr1a1a zebrafish mutants causes impaired insulin receptor signaling and microvascular alterations}, year={2021}, pages={1-15}, language={eng}, issn={2198-3844}, volume={8}, note={Gesehen am 05.12.2022}, journal={Advanced science}, doi={10.1002/advs.202101281}, url={https://doi.org/10.1002/advs.202101281}, library={UB}, } @book{UBHD-68384914, author={Schmitt, Felix and Uhle, Florian and Weigand, Markus A. and Brenner, Thorsten and Morgenstern, Jakob and Manolov, Vasil and Fleming, Thomas and Saeedi, Mohammed al and Hackert, Thilo and Bruckner, Thomas}, title={Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study}, publisher={Springer}, address={Heidelberg}, year={2019}, pages={1 Online-Ressource (15 Seiten)}, language={eng}, note={In: Annals of intensive care, 9 (2019), Nr. 19. pp. 1-15. ISSN 2110-8520}, doi={10.1186/s13613-019-0499-6}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-260204}, library={UB}, } @article{UBHD-68360933, author={Schmitt, Felix and Uhle, Florian and Weigand, Markus A. and Brenner, Thorsten and Morgenstern, Jakob and Manolov, Vasil and Fleming, Thomas and Saeedi, Mohammed al and Hackert, Thilo and Bruckner, Thomas}, title={Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality}, subtitle={results of an observational pilot study}, year={2019}, pages={15 S.}, language={eng}, issn={2110-5820}, volume={9(2019) Artikel-Nummer 19}, number={15 Seiten}, note={Gesehen am 21.02.2019}, journal={Annals of intensive care}, doi={10.1186/s13613-019-0499-6}, url={http://dx.doi.org/10.1186/s13613-019-0499-6}, library={UB}, } @article{UBHD-68109315, author={Schmoch, Thomas and Uhle, Florian and Siegler, Benedikt Hermann and Fleming, Thomas and Morgenstern, Jakob and Nawroth, Peter Paul and Weigand, Markus A. and Brenner, Thorsten}, title={The glyoxalase system and methylglyoxal-derived carbonyl stress in sepsis}, subtitle={glycotoxic aspects of sepsis pathophysiology}, year={2017}, language={eng}, issn={1422-0067 and 1661-6596}, volume={18(2017}, note={Gesehen am 12.04.2017}, journal={International journal of molecular sciences}, doi={10.3390/ijms18030657}, url={http://dx.doi.org/10.3390/ijms18030657}, library={UB}, } @article{UBHD-68561899, author={Schm{\"o}hl, Felix and Peters, Verena and Schmitt, Claus P. and Poschet, Gernot and B{\"u}ttner, Michael and Li, Xiaogang and Poth, Tanja and Volk, Nadine and Morgenstern, Jakob and Fleming, Thomas and Nawroth, Peter Paul and Kroll, Jens}, title={CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications}, year={2019}, pages={4551-4568}, language={eng}, issn={1420-9071}, volume={76}, number={22}, note={Gesehen am 06.04.2020}, journal={Cellular and molecular life sciences}, doi={10.1007/s00018-019-03127-z}, } @article{UBHD-68424690, author={Schumacher, Dagmar and Morgenstern, Jakob and Oguchi, Yoko and Volk, Nadine and Kopf, Stefan and Gr{\"o}ner, Jan and Nawroth, Peter Paul and Fleming, Thomas and Freichel, Marc}, title={Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes}, year={2018}, pages={143-152}, language={eng}, issn={2212-8778}, volume={18}, note={Gesehen am 28.08.2019}, journal={Molecular metabolism}, doi={10.1016/j.molmet.2018.09.005}, } @article{UBHD-69032599, author={Tabler, Christoph Tobias and Lodd, Elisabeth and Bennewitz, Katrin and Middel, Chiara Simone and Erben, Vanessa and Schr{\"o}der, Hannes and Poth, Tanja and Fleming, Thomas and Morgenstern, Jakob and Haußer-Siller, Ingrid and Sticht, Carsten and Poschet, Gernot and Szendr{\"o}di, Julia and Nawroth, Peter Paul and Kroll, Jens}, title={Loss of glyoxalase 2 alters the glucose metabolism in zebrafish}, year={2023}, pages={1-15}, language={eng}, issn={2213-2317}, volume={59(2023) vom: Feb.}, number={Artikel-ID 102576}, note={Online ver{\"o}ffentlicht am 14. Dezember 2022, Dateiversion vom 17. Dezember 2022 ; Gesehen am 01.02.2023}, journal={Redox Biology}, doi={10.1016/j.redox.2022.102576}, } @article{UBHD-69150955, author={Taylor, Jacqueline and Uhl, Leonie and Moll, Iris and Hasan, Sana Safatul and Wiedmann, Lena and Morgenstern, Jakob and Giaimo, Benedetto Daniele and Friedrich, Tobias and Alsina Sanchis, Elisenda and De Angelis Rigotti, Francesca and M{\"u}lfarth, Ronja and Kaltenbach, Sarah and Schenk, Darius and Nickel, Felix and Fleming, Thomas and Sprinzak, David and Mogler, Carolin and Korff, Thomas and Billeter, Adrian and M{\"u}ller, Beat P. and Berriel Diaz, Mauricio and Borggrefe, Tilman and Herzig, Stephan and Rohm, Maria and Rodriguez-Vita, Juan and Fischer, Andreas}, title={Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia}, year={2023}, pages={1544-1560}, language={eng}, issn={2662-1347}, volume={4}, number={11}, note={Insgesamt 38 Seiten (S. 1544-1560, 15 ungez{\"a}hlte Seiten, S. 1-6) ; Online ver{\"o}ffentlicht: 25. September 2023 ; Gesehen am 08.12.2023}, journal={Nature cancer}, doi={10.1038/s43018-023-00622-y}, } @article{UBHD-68569395, author={Urban, Ivelina and Turinsky, Martin and Gehrmann, Sviatlana and Morgenstern, Jakob and Brune, Maik and Milewski, Moritz R. and Wagner, Andreas H. and Rumig, Cordula and Fleming, Thomas and Leuschner, Florian and Gleißner, Christian A. and Hecker, Markus}, title={15-deoxy-[delta]12,14-prostaglandin J2 reinforces the anti-inflammatory capacity of endothelial cells with a genetically determined NO deficit}, year={2019}, pages={282-294}, language={eng}, issn={1524-4571}, volume={125}, number={3}, note={Im Titel ist [delta] als griechischer Buchstabe dargestellt ; Im Titel ist die Zahl 2 bei J2 tiefgestellt ; Gesehen am 22.04.2020}, journal={Circulation research}, doi={10.1161/CIRCRESAHA.118.313820}, } @article{UBHD-68924871, author={Wohlfart, David Philipp and Lou, Bowen and Middel, Chiara Simone and Morgenstern, Jakob and Fleming, Thomas and Sticht, Carsten and Haußer-Siller, Ingrid and Hell, R{\"u}diger and Hammes, Hans-Peter and Szendr{\"o}di, Julia and Nawroth, Peter Paul and Kroll, Jens}, title={Accumulation of acetaldehyde in aldh2.1-/- zebrafish causes increased retinal angiogenesis and impaired glucose metabolism}, year={2022}, pages={1-15}, language={eng}, issn={2213-2317}, volume={50(2022) vom: Apr.}, number={Artikel-ID 102249}, note={Im Titel ist "-/-" hochgestellt ; Gesehen am 01.06.2022}, journal={Redox Biology}, doi={10.1016/j.redox.2022.102249}, } @article{UBHD-68945319, author={Wolff, Gretchen and Sakurai, Minako and Mhamane, Amit and Troullinaki, Maria and Maida, Adriano and Deligiannis, Ioannis K. and Yin, Kelvin and Weber, Peter and Morgenstern, Jakob and Wieder, Annika and Kwon, Yun and Sekar, Revathi and Zeigerer, Anja and Roden, Michael and Bl{\"u}her, Matthias and Volk, Nadine and Poth, Tanja and Hackert, Thilo and Wiedmann, Lena and De Angelis Rigotti, Francesca and Rodriguez-Vita, Juan and Fischer, Andreas and Mukthavaram, Rajesh and Limphong, Pattraranee and Tachikawa, Kiyoshi and Karmali, Priya and Payne, Joseph and Chivukula, Padmanabh and {\"U}st{\"u}nel, Bilgen Ekim and Martinez-Jimenez, Celia P. and Szendr{\"o}di, Julia and Nawroth, Peter Paul and Herzig, Stephan}, title={Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function}, year={2022}, pages={1-13}, language={eng}, issn={2212-8778}, volume={60(2022) vom: Juni}, number={Artikel-ID 101487}, note={Gesehen am 21.07.2022}, journal={Molecular metabolism}, doi={10.1016/j.molmet.2022.101487}, }