@article{UBHD-68410751, author={Brachs, Sebastian and Kannt, Aimo}, title={Genetic nicotinamide N-methyltransferase (Nnmt) deficiency in male mice improves insulin sensitivity in diet-induced obesity but does not affect glucose tolerance}, year={2019}, pages={527-542}, language={eng}, issn={1939-327X}, volume={68}, number={3}, note={Published first December 14, 2018 ; Gesehen am 22.07.2019}, journal={Diabetes}, doi={10.2337/db18-0780}, } @article{UBHD-68800432, author={Dommel, Sebastian and Hoffmann, Anne and Berger, Claudia and Kern, Matthias and Kl{\"o}ting-Bl{\"u}her, Nora and Kannt, Aimo and Bl{\"u}her, Matthias}, title={Effects of whole-body Adenylyl cyclase 5 (Adcy5) deficiency on systemic insulin sensitivity and adipose tissue}, year={2021}, pages={1-21}, language={eng}, issn={1422-0067 and 1661-6596}, volume={22}, note={Gesehen am 11.11.2021}, journal={International journal of molecular sciences}, doi={10.3390/ijms22094353}, } @article{UBHD-69323605, author={Duriez, Marion and Jacquet, Agnes and Hoet, Lucile and Roche, Sandrine and Bock, Marie-Dominique and Rocher, Corinne and Haussy, Gilles and Vigé, Xavier and Bocskei, Zsolt and Slavnic, Tamara and Martin, Valérie and Guillemot, Jean-Claude and Didier, Michel and Kannt, Aimo and Orsini, Cécile and Mikol, Vincent and Fèvre, Anne-Céline Le}, title={A 3D human liver model of nonalcoholic steatohepatitis}, year={2020}, pages={359-370}, language={eng}, issn={2310-8819}, volume={8}, number={4}, note={Gesehen am 31.03.2025}, journal={Journal of clinical and translational hepatology}, doi={10.14218/JCTH.2020.00015}, } @article{UBHD-68443738, author={Elvert, Ralf and Kannt, Aimo}, title={Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control}, subtitle={A comparative study between mice and non-human primates}, year={2018}, pages={1836-1851}, language={eng}, issn={1463-1326}, volume={20}, number={8}, note={Gesehen am 22.10.2019}, journal={Diabetes, obesity and metabolism}, doi={10.1111/dom.13212}, } @article{UBHD-68443715, author={Elvert, Ralf and Kannt, Aimo}, title={Team players or opponents}, subtitle={coadministration of selective glucagon and GLP-1 receptor agonists in obese diabetic monkeys}, year={2018}, pages={3105-3119}, language={eng}, issn={1945-7170}, volume={159}, number={8}, note={Gesehen am 22.10.2019}, journal={Endocrinology}, doi={10.1210/en.2018-00399}, } @article{UBHD-68443810, author={Gordin, Daniel and Kannt, Aimo}, title={Characterization of glycolytic enzymes and pyruvate kinase M2 in Type 1 and 2 diabetic nephropathy}, year={2019}, pages={1263-1273}, language={eng}, issn={1935-5548}, volume={42}, number={7}, note={Gesehen am 22.10.2019}, journal={Diabetes care}, doi={10.2337/dc18-2585}, } @book{UBHD-68114414, author={Kannt, Aimo}, organization={Universit{\"a}t Heidelberg}, title={Drug discovery in cardiovascular and metabolic diseases}, address={Heidelberg}, year={2016}, pages={1 Band (verschiedene Seitenz{\"a}hlungen)}, language={eng}, note={Publikationsbasierte Habilitationsschrift bestehend aus 6 Beitr{\"a}gen}, school={Habilitationsschrift, Ruprecht-Karls-Universit{\"a}t Heidelberg, 2017}, library={UB [Signatur: 2017 U 290] ; UW [Signatur: Habil. 17.7]}, } @article{UBHD-68227081, author={Kannt, Aimo}, title={Management of nicotinamide N-methyltransferase overexpression}, subtitle={inhibit the enzyme or reduce nicotinamide intake? : reply to Zhou S, Li D, Zhou Y [letter]}, year={2015}, pages={2193-2194}, language={eng}, issn={1432-0428}, volume={58}, number={9}, note={Gesehen am 06.03.2018}, journal={Diabetologia}, doi={10.1007/s00125-015-3678-5}, } @article{UBHD-68437738, author={Kannt, Aimo}, title={A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders}, year={2018}, pages={15 S.}, language={eng}, issn={2045-2322}, volume={8(2018) Artikel-Nummer 3660}, number={15 Seiten}, note={Gesehen am 10.10.2019}, journal={Scientific reports}, doi={10.1038/s41598-018-22081-7}, } @article{UBHD-68378873, author={Kannt, Aimo and Wieland, Thomas}, title={Managing risks in drug discovery}, subtitle={reproducibility of published findings}, year={2016}, pages={353-360}, language={eng}, issn={1432-1912}, volume={389}, number={4}, note={Gesehen am 08.04.2019}, journal={Naunyn-Schmiedeberg's archives of pharmacology}, doi={10.1007/s00210-016-1216-8}, } @article{UBHD-69210752, author={Mishra, Anurag and Castañeda, Tamara R. and Bader, Erik and Elshorst, Bettina and Cummings, Sheila and Scherer, Petra and Bangari, Dinesh S. and Loewe, Claudia and Schreuder, Herman and P{\"o}verlein, Christoph and Helms, Mike and Jones, Seth and Zech, Gernot and Licher, Thomas and Wagner, Michael and Schudok, Manfred and de Hoop, Meltsje and Plowright, Alleyn T. and Atzrodt, Jens and Kannt, Aimo and Laitinen, Iina and Derdau, Volker}, title={Triantennary GalNAc molecular imaging probes for monitoring hepatocyte function in a rat model of nonalcoholic steatohepatitis}, year={2020}, pages={1-9}, language={eng}, issn={2198-3844}, volume={7}, note={Online ver{\"o}ffentlicht: 9. November 2020 ; Gesehen am 03.05.2024}, journal={Advanced science}, doi={10.1002/advs.202002997}, } @article{UBHD-68995790, author={Qiu, Jiedong and Yard, Benito A. and Kr{\"a}mer, Bernhard and van Goor, Harry and van Dijk, Peter and Kannt, Aimo}, title={Association between serum carnosinase concentration and activity and renal function impairment in a type-2 diabetes cohort}, year={2022}, pages={1-8}, language={eng}, issn={1663-9812}, volume={13}, number={Artikel-ID 899057}, note={Gesehen am 05.12.2022}, journal={Frontiers in pharmacology}, doi={10.3389/fphar.2022.899057}, } @article{UBHD-68436876, author={Qiu, Jiedong and Hauske, Sibylle J. and Zhang, Shiqi and Albrecht, Thomas and Pastene, Diego O. and Peters, Verena and Kannt, Aimo and Yard, Benito A. and Kr{\"a}mer, Bernhard and Hammes, Hans-Peter and Rodriguez-Niño, Angelica}, title={Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity}, year={2019}, pages={7-16}, language={eng}, issn={1438-2199}, volume={51}, number={1}, note={Published online: 20 June 2018 ; Gesehen am 09.10.2019}, journal={Amino acids}, doi={10.1007/s00726-018-2601-z}, } @article{UBHD-69366534, author={Qiu, Jiedong and Yard, Benito A. and Kr{\"a}mer, Bernhard and van Goor, Harry and van Dijk, Peter R. and Kannt, Aimo}, title={Serum carnosinase 1 is not associated with insulin resistance or glucose metabolism in a type 1 diabetes cohort}, year={2025}, pages={1-8}, language={eng}, issn={2227-9059}, volume={13}, note={Gesehen am 17.07.2025}, journal={Biomedicines}, doi={10.3390/biomedicines13020366}, } @article{UBHD-68619546, author={Ruf, Sven and Kannt, Aimo}, title={Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase}, year={2018}, pages={922-925}, language={eng}, issn={1464-3405}, volume={28}, number={5}, note={Gesehen am 22.07.2020}, journal={Bioorganic & medicinal chemistry letters}, doi={10.1016/j.bmcl.2018.01.058}, } @article{UBHD-68315296, author={Swaminathan, Srinivasan and Kannt, Aimo}, title={Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide}, year={2017}, pages={416-422}, language={eng}, issn={1090-2104}, volume={491}, number={2}, note={Gesehen am 15.10.2018 ; Available online 15 July 2017}, journal={Biochemical and biophysical research communications}, doi={10.1016/j.bbrc.2017.07.087}, } @article{UBHD-68212977, author={Winkel, Angelika F. and Kannt, Aimo}, title={Characterization of RA839, a noncovalent small molecule binder to keap1 and selective activator of Nrf2 signaling}, year={2015}, pages={28446-28455}, language={eng}, issn={1083-351X}, volume={290}, number={47}, note={Gesehen am 24.01.2018}, journal={The journal of biological chemistry}, doi={10.1074/jbc.M115.678136}, } @article{UBHD-68681826, author={Zavaritskaya, Olga and Dudem, Srikanth and Ma, Dongyu and Rabab, Kaneez E. and Albrecht, Sarah and Tsvetkov, Dmitry and Kassmann, Mario and Thornbury, Keith and Mladenov, Mitko and Kammermeier, Claire and Sergeant, Gerard and Mullins, Nicholas and Wouappi, Ornella and Wurm, Hannah and Kannt, Aimo and Gollasch, Maik and Hollywood, Mark A. and Schubert, Rudolf}, title={Vasodilation of rat skeletal muscle arteries by the novel BK channel opener GoSlo is mediated by the simultaneous activation of BK and Kv7 channels}, year={2020}, pages={1164-1186}, language={eng}, issn={1476-5381}, volume={177}, number={5}, note={First published: 28 October 2019 ; Im Titel ist "v" bei "Kv7" tiefgestellt ; Gesehen am 20.01.2021}, journal={British journal of pharmacology}, doi={10.1111/bph.14910}, url={https://doi.org/10.1111/bph.14910}, library={UB}, }