@article{UBHD-68749880, author={Dentro, Stefan C. and Kleinheinz, Kortine and Schlesner, Matthias}, title={Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes}, year={2021}, pages={2239-2254.e39}, language={eng}, issn={1097-4172}, volume={184}, number={8}, note={Gesehen am 17.06.2021}, journal={Cell}, doi={10.1016/j.cell.2021.03.009}, } @article{UBHD-68613375, author={Gerstung, Moritz and Jolly, Clemency and Leshchiner, Ignaty and Dentro, Stefan C. and Gonzalez, Santiago and Rosebrock, Daniel and Mitchell, Thomas J. and Rubanova, Yulia and Anur, Pavana and Yu, Kaixian and Tarabichi, Maxime and Deshwar, Amit and Wintersinger, Jeff and Kleinheinz, Kortine and Vázquez-García, Ignacio and Haase, Kerstin and Jerman, Lara and Sengupta, Subhajit and Macintyre, Geoff and Malikic, Salem and Donmez, Nilgun and Livitz, Dimitri G. and Cmero, Marek and Demeulemeester, Jonas and Schumacher, Steven and Fan, Yu and Yao, Xiaotong and Lee, Juhee and Schlesner, Matthias and Boutros, Paul C. and Bowtell, David D. and Zhu, Hongtu and Getz, Gad and Imielinski, Marcin and Beroukhim, Rameen and Sahinalp, S. Cenk and Ji, Yuan and Peifer, Martin and Markowetz, Florian and Mustonen, Ville and Yuan, Ke and Wang, Wenyi and Morris, Quaid D. and Spellman, Paul T. and Wedge, David C. and Loo, Peter Van}, title={The evolutionary history of 2,658 cancers}, year={2020}, pages={122-128}, language={eng}, issn={1476-4687}, volume={578}, number={7793}, note={Das pdf beteht aus 23 Seiten ; Gesehen am 03.07.2020}, journal={Nature}, doi={10.1038/s41586-019-1907-7}, } @article{UBHD-68263864, author={Gießler, Klara Monika and Kleinheinz, Kortine and H{\"u}bschmann, Daniel and Balasubramanian, Gnana Prakash and Dubash, Taronish Dorab and Dieter, Sebastian M. and Siegl, Christine and Herbst, Friederike and Weber, Sarah and Hoffmann, Christopher M. and Fronza, Raffaele and Buchhalter, Ivo and Paramasivam, Nagarajan and Eils, Roland and Schmidt, Manfred and Kalle, Christof von and Schneider, Martin and Ulrich, Alexis and Scholl, Claudia and Fr{\"o}hling, Stefan and Weichert, Wilko and Brors, Benedikt and Schlesner, Matthias and Ball, Claudia R. and Glimm, Hanno}, title={Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer}, year={2017}, pages={2073-2088}, language={eng}, issn={1540-9538}, volume={214}, number={7}, note={Published June 1, 2017 ; Gesehen am 20.06.2018}, journal={Journal of experimental medicine}, doi={10.1084/jem.20162017}, } @article{UBHD-68394778, author={Gr{\"o}schel, Stefan and H{\"u}bschmann, Daniel and Raimondi, Francesco and Horak, Peter and Kleinheinz, Kortine and Chudasama, Priya and Heilig, Christoph E. and Eils, Roland and Kalle, Christof von and Scholl, Claudia and Stenzinger, Albrecht and Brors, Benedikt and Russell, Robert B. and Glimm, Hanno and Fr{\"o}hling, Stefan}, title={Defective homologous recombination DNA repair as therapeutic target in advanced chordoma}, year={2019}, pages={9 S.}, language={eng}, issn={2041-1723}, volume={10(2019) Artikel-Nummer 1635}, number={9 Seiten}, note={Gesehen am 03.06.2019}, journal={Nature Communications}, doi={10.1038/s41467-019-09633-9}, } @article{UBHD-68351910, author={Haller, Florian and K{\"o}rner, Cindy and Weichenhan, Dieter and Lutsik, Pavlo and Kleinheinz, Kortine and Eils, Roland and Plass, Christoph and Wiemann, Stefan}, title={Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands}, year={2019}, language={eng}, issn={2041-1723}, volume={10(2019) Artikel-Nummer 368}, number={13 Seiten}, note={Gesehen am 25.01.2019}, journal={Nature Communications}, doi={10.1038/s41467-018-08069-x}, } @article{UBHD-68873825, author={H{\"u}bschmann, Daniel and Kleinheinz, Kortine and Wagener, Rabea and Bernhart, Stephan H. and López, Cristina and Toprak, Umut and Sungalee, Stéphanie and Ishaque, Naveed and Kretzmer, Helene and Kreuz, Markus and Waszak, Sebastian Martin and Paramasivam, Nagarajan and Ammerpohl, Ole and Aukema, Sietse M. and Beekman, Renée and Bergmann, Anke K. and Bieg, Matthias and Binder, Hans and Borkhardt, Arndt and Borst, Christoph and Brors, Benedikt and Bruns, Philipp and Carrillo de Santa Pau, Enrique and Claviez, Alexander and Doose, Gero and Haake, Andrea and Karsch, Dennis and Haas, Siegfried and Hansmann, Martin-Leo and Hoell, Jessica I. and Hovestadt, Volker and Huang, Bingding and Hummel, Michael and J{\"a}ger-Schmidt, Christina and Kerssemakers, Jules and Korbel, Jan Oliver and Kube, Dieter and Lawerenz, Christian and Lenze, Dido and Martens, Joost H. A. and Ott, German and Radlwimmer, Bernhard and Reisinger, Eva and Richter, Julia and Rico, Daniel and Rosenstiel, Philip and Rosenwald, Andreas and Schillhabel, Markus and Stilgenbauer, Stephan and Stadler, Peter F. and Martín-Subero, José I. and Szczepanowski, Monika and Warsow, Gregor and Weniger, Marc A. and Zapatka, Marc and Valencia, Alfonso and Stunnenberg, Hendrik G. and Lichter, Peter and M{\"o}ller, Peter and Loeffler, Markus and Eils, Roland and Klapper, Wolfram and Hoffmann, Steve and Tr{\"u}mper, Lorenz and K{\"u}ppers, Ralf and Schlesner, Matthias and Siebert, Reiner}, title={Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas}, year={2021}, pages={2002-2016}, language={eng}, issn={1476-5551}, volume={35}, number={7}, note={Affiliations: Daniel H{\"u}bschmann, Kortine Kleinheinz, Rabea Wagener, Stephan H. Bernhart, Cristina López, Umut H. Toprak, Stephanie Sungalee, Naveed Ishaque, Helene Kretzmer, Markus Kreuz, Sebastian M. Waszak, Nagarajan Paramasivam, Ole Ammerpohl, Sietse M. Aukema, Renée Beekman, Anke K. Bergmann, Matthias Bieg, Hans Binder, Arndt Borkhardt, Christoph Borst, Benedikt Brors, Philipp Bruns, Enrique Carrillo de Santa Pau, Alexander Claviez, Gero Doose, Andrea Haake, Dennis Karsch, Siegfried Haas, Martin-Leo Hansmann, Jessica I. Hoell, Volker Hovestadt, Bingding Huang, Michael Hummel, Christina J{\"a}ger-Schmidt, Jules N.A. Kerssemakers, Jan O. Korbel, Dieter Kube, Chris Lawerenz, Dido Lenze, Joost H.A. Martens, German Ott, Bernhard Radlwimmer, Eva Reisinger, Julia Richter, Daniel Rico, Philip Rosenstiel, Andreas Rosenwald, Markus Schillhabel, Stephan Stilgenbauer, Peter F. Stadler, José I. Martín-Subero, Monika Szczepanowski, Gregor Warsow, Marc A. Weniger, Marc Zapatka, Alfonso Valencia, Hendrik G. Stunnenberg, Peter Lichter, Peter M{\"o}ller, Markus Loeffler, Roland Eils, Wolfram Klapper, Steve Hoffmann, Lorenz Tr{\"u}mper, ICGC MMML-Seq consortium, ICGC DE-Mining consortium, BLUEPRINT consortium, Ralf K{\"u}ppers, Matthias Schlesner, Reiner Siebert ; Gesehen am 03.02.2022}, journal={Leukemia}, doi={10.1038/s41375-021-01251-z}, } @article{UBHD-68491160, author={Ishaque, Naveed and Abba, Mohammed L. and Patil, Nitin and Paramasivam, Nagarajan and H{\"u}bschmann, Daniel and Leupold, J{\"o}rg and Balasubramanian, Gnana Prakash and Kleinheinz, Kortine and Toprak, Umut and Hutter, Barbara and Benner, Axel and Kerssemakers, Jules and Marx, Alexander and Eils, J{\"u}rgen and Schlesner, Matthias and Eils, Roland and Brors, Benedikt and Allgayer, Heike}, title={Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer}, year={2018}, pages={14 S.}, language={eng}, issn={2041-1723}, volume={9(2018) Artikel-Nummer 4782}, number={14 Seiten}, note={Gesehen am 19.02.2020}, journal={Nature Communications}, doi={10.1038/s41467-018-07041-z}, } @article{UBHD-68325157, author={Jabs, Julia and Park, Jeongbin and Jechow, Katharina and Kleinheinz, Kortine and Schneider, Marc and Meister, Michael and Spaich, Saskia and S{\"u}tterlin, Marc and Schlesner, Matthias and Eils, Roland and Conrad, Christian}, title={Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations}, year={2017}, pages={16 S.}, language={eng}, issn={1744-4292}, volume={13}, note={Gesehen am 06.11.2018}, journal={Molecular systems biology}, doi={10.15252/msb.20177697}, } @book{UBHD-68209953, author={Kleinheinz, Kortine}, organization={Universit{\"a}t Heidelberg}, title={ACEseq - allele-specific copy number estimation from whole genome sequencing and its application in heterogeneity and integrative analyses of cancer}, address={Heidelberg}, year={2017}, pages={xxi, 154 Seiten}, language={eng}, school={Dissertation, Ruperto-Carola University of Heidelberg, 2017}, library={UB [Signatur: 2018 U 15]}, } @article{UBHD-69055063, author={López, Cristina and Schleußner, Nikolai and Bernhart, Stephan H. and Kleinheinz, Kortine and Sungalee, Stephanie and Sczakiel, Henrike L. and Kretzmer, Helene and Toprak, Umut and Glaser, Selina and Wagener, Rabea and Ammerpohl, Ole and Bens, Susanne and Giefing, Maciej and González Sánchez, Juan Carlos and Apic, Gordana and H{\"u}bschmann, Daniel and Janz, Martin and Kreuz, Markus and Mottok, Anja and Muller, Judith M. and Seufert, Julian and Hoffmann, Steve and Korbel, Jan Oliver and Russell, Robert B. and Schule, Roland and Trumper, Lorenz and Klapper, Wolfram and Radlwimmer, Bernhard and Lichter, Peter and Kuppers, Ralf and Schlesner, Matthias and Mathas, Stephan and Siebert, Reiner}, title={Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas}, year={2023}, pages={543-554}, language={eng}, issn={1592-8721}, volume={108}, number={2 vom: Feb.}, note={Vorver{\"o}ffentlicht: April 28, 2022 ; Gesehen am 23.03.2023}, journal={Haematologica}, doi={10.3324/haematol.2021.280005}, } @article{UBHD-68392776, author={López, Cristina and Kleinheinz, Kortine and H{\"u}bschmann, Daniel and Raimondi, Francesco and Russell, Robert B. and Eils, Roland}, title={Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma}, year={2019}, pages={19 S.}, language={eng}, issn={2041-1723}, volume={10(2019) Artikel-Nummer 1459}, number={19 Seiten}, note={Gesehen am 24.05.2019}, journal={Nature Communications}, doi={10.1038/s41467-019-08578-3}, } @article{UBHD-68261293, author={Sahm, Felix and H{\"u}bschmann, Daniel and Kleinheinz, Kortine and Buchhalter, Ivo and Sill, Martin and Stichel, Damian and Schrimpf, Daniel and Herold-Mende, Christel and Eils, Roland and Sturm, Dominik and Jones, David T. W. and Pfister, Stefan and Deimling, Andreas von}, title={Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature}, year={2017}, pages={155-158}, language={eng}, issn={1432-0533}, volume={134}, number={1}, note={Published online: 4 May 2017 ; Gesehen am 14.06.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-017-1715-9}, } @article{UBHD-68380484, author={Wagener, Rabea and Kleinheinz, Kortine and H{\"u}bschmann, Daniel}, title={IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas}, year={2018}, pages={2280-2285}, language={eng}, issn={1528-0020}, volume={132}, number={21}, note={Im Titel ist "+" hochgestellt ; Gesehen am 15.04.2019}, journal={Blood}, doi={10.1182/blood-2018-03-842088}, } @article{UBHD-68380521, author={Wagener, Rabea and Raimondi, Francesco and Kleinheinz, Kortine and H{\"u}bschmann, Daniel and Russell, Robert B.}, title={The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma}, year={2019}, pages={962-966}, language={eng}, issn={1528-0020}, volume={133}, number={9}, note={Prepublished online as Blood First Edition paper, 19 December 2018 ; Gesehen am 15.04.2019}, journal={Blood}, doi={10.1182/blood-2018-07-864025}, } @article{UBHD-68401989, author={Warsow, Gregor and H{\"u}bschmann, Daniel and Kleinheinz, Kortine and Nientiedt, Cathleen and Heller, Martina and Van Coile, Laura and Tolstov, Yanis and Trennheuser, Lukas and Wieczorek, Kathrin and Pecqueux, Carine and Gasch, Claudia and Kuru, Timur Hasan and Nyarangi-Dix, Joanne and Hatiboglu, Gencay and Teber, Dogu and Stenzinger, Albrecht and Roth, Wilfried and Hadaschik, Boris and Pahernik, Sascha and J{\"a}ger, Dirk and Gr{\"u}llich, Carsten and Duensing, Anette and Eils, Roland and Schlesner, Matthias and S{\"u}ltmann, Holger and Hohenfellner, Markus and Duensing, Stefan}, title={Genomic features of renal cell carcinoma with venous tumor thrombus}, year={2018}, pages={12 S.}, language={eng}, issn={2045-2322}, volume={8(2018) Artikel-Nummer 7477}, number={12 Seiten}, note={Gesehen am 26.06.2019}, journal={Scientific reports}, doi={10.1038/s41598-018-25544-z}, }