@article{UBHD-68646183, author={Berger, Anne Katrin and Mughal, Sadaf Shabbir and Allg{\"a}uer, Michael and Springfeld, Christoph and Hackert, Thilo and Weber, Tim and Naumann, Patrick and Hutter, Barbara and Horak, Peter and Jahn, Arne and Schr{\"o}ck, Evelin and Haag, Georg Martin and Apostolidis, Leonidas and J{\"a}ger, Dirk and Stenzinger, Albrecht and Fr{\"o}hling, Stefan and Glimm, Hanno and Heining, Christoph}, title={Metastatic adult pancreatoblastoma}, subtitle={multimodal treatment and molecular characterization of a very rare disease}, year={2020}, pages={425-432}, language={eng}, issn={1424-3911}, volume={20}, number={3}, note={Gesehen am 08.10.2020}, journal={Pancreatology}, doi={10.1016/j.pan.2020.02.017}, } @article{UBHD-68176403, author={Breitkreutz, Iris and Kosely, Florentina and Heining, Christoph and Hillengaß, Jens and Egerer, Gerlinde and Ho, Anthony Dick and Goldschmidt, Hartmut and Raab, Marc-Steffen}, title={Dose-intensified bendamustine followed by autologous peripheral blood stem cell support in relapsed and refractory multiple myeloma with impaired bone marrow function}, year={2016}, pages={200-207}, language={eng}, issn={1099-1069}, volume={34}, number={4}, note={First published: 18 March 2015 ; Gesehen am 06.10.2017}, journal={Hematological oncology}, doi={10.1002/hon.2199}, } @article{UBHD-68430763, author={Busch, Elena and Heining, Christoph and Weber, Tim and Lasitschka, Felix and Schemmer, Peter and Schirmacher, Peter and Weiss, Karl Heinz and Glimm, Hanno and Brors, Benedikt and Weichert, Wilko and J{\"a}ger, Dirk and Fr{\"o}hling, Stefan and Springfeld, Christoph}, title={Dauerhafte Remission unter dualer HER2-Blockade mit Trastuzumab und Pertuzumab bei metastasiertem Gallenblasenkarzinom}, year={2016}, pages={426-430}, language={ger and eng}, issn={1439-7803}, volume={54}, number={05}, note={Gesehen am 17.09.2019}, journal={Zeitschrift f{\"u}r Gastroenterologie}, doi={10.1055/s-0042-103498}, } @article{UBHD-68288210, author={Chudasama, Priya and Renner, Marcus and Alldinger, Ingo and Schimmack, Simon and J{\"a}ger, Dirk and Kalle, Christof von and Schirmacher, Peter and Heining, Christoph and Gr{\"o}schel, Stefan and Glimm, Hanno and Mechtersheimer, Gunhild and Fr{\"o}hling, Stefan}, title={Targeting fibroblast growth factor receptor 1 for treatment of soft-tissue sarcoma}, year={2017}, pages={962-973}, language={eng}, issn={1557-3265}, volume={23}, number={4}, note={Gesehen am 24.07.2018}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-16-0860}, } @article{UBHD-68320075, author={Dieter, Sebastian M. and Heining, Christoph and H{\"u}bschmann, Daniel and Hutter, Barbara and Ehrenberg, Karl Roland and Fr{\"o}hlich, Martina and Scholl, Claudia and Mavratzas, Athanasios and Jung, Carla Sabine and Gr{\"o}schel, Stefan and Kalle, Christof von and Eils, Roland and Brors, Benedikt and Penzel, Roland and Kriegsmann, Mark and Reuss, David and Schirmacher, Peter and Stenzinger, Albrecht and Federspil, Philippe A. and Weichert, Wilko and Glimm, Hanno and Fr{\"o}hling, Stefan}, title={Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma}, year={2017}, pages={142-148}, language={eng}, issn={1569-8041}, volume={28}, number={1}, note={Published online 29 September 2016 ; Gesehen am 23.10.2018}, journal={Annals of oncology}, doi={10.1093/annonc/mdw446}, } @incollection{UBHD-68557956, author={Glocker, Katrin and Ahlbrandt, Janko and Knurr, Alexander and Horak, Peter and Heining, Christoph and {\"U}ckert, Frank}, title={Finding options beyond standard of care in oncology}, subtitle={a proposal for workflows utilizing knowledge databases}, year={2019}, pages={950-953}, language={eng}, isbn={9781643680033}, note={Gesehen am 25.03.2020}, booktitle={MEDINFO 2019}, editor={Ohno-Machado, Lucila and Séroussi, Brigitte}, doi={10.3233/SHTI190364}, } @article{UBHD-68286163, author={Heining, Christoph and Horak, Peter and Richter, Daniela and Penzel, Roland and Endris, Volker and Ehrenberg, Karl Roland and Frank, Stephanie and Giese, Nathalia and Strobel, Oliver and Hackert, Thilo and Springfeld, Christoph and Bergmann, Frank and Kalle, Christof von and Scholl, Claudia and Ball, Claudia R. and Stenzinger, Albrecht and Fr{\"o}hling, Stefan and Glimm, Hanno}, title={NRG1 fusions in KRAS wild-type pancreatic cancer}, year={2018}, pages={1087-1095}, language={eng}, issn={2159-8290}, volume={8}, number={9}, note={Published onlinefirst May 25, 2018 ; Gesehen am 17.07.2018}, journal={Cancer discovery}, doi={10.1158/2159-8290.CD-18-0036}, } @article{UBHD-68244716, author={Heining, Christoph and Horak, Peter and Gr{\"o}schel, Stefan and Glimm, Hanno and Fr{\"o}hling, Stefan}, title={Personalisierte Onkologie}, year={2017}, pages={804-811}, language={ger}, issn={1432-2102}, volume={57}, number={10}, note={Gesehen am 19.04.2018}, journal={Der Radiologe}, doi={10.1007/s00117-017-0297-9}, } @article{UBHD-68575749, author={Heining, Christoph and Horak, Peter and Gr{\"o}schel, Stefan and Glimm, Hanno and Fr{\"o}hling, Stefan}, title={Personalisierte Medizin}, subtitle={Strukturen, Tumorboards, Visionen}, year={2016}, pages={452-459}, language={ger}, issn={1863-5490}, volume={28}, number={4}, note={Online publiziert: 24. Januar 2017 ; Gesehen am 12.05.2020}, journal={Medizinische Genetik}, doi={10.1007/s11825-016-0111-5}, } @article{UBHD-68514220, author={Heining, Christoph and Kalle, Christof von}, title={Zuk{\"u}nftige Aufgaben onkologischer Spitzenzentren in der Forschung}, subtitle={ =}, year={2016}, pages={152-157}, language={ger and eng}, issn={1433-0415}, volume={22}, number={3}, note={Gesehen am 13.03.2020}, journal={Der Onkologe}, doi={10.1007/s00761-015-2935-z}, } @article{UBHD-68301919, author={Horak, Peter and Heining, Christoph and Gr{\"o}schel, Stefan and Hutter, Barbara and Fr{\"o}hlich, Martina and H{\"u}bschmann, Daniel and Schlesner, Matthias and Eils, Roland and Richter, Daniela and Pf{\"u}tze, Katrin and Ge{\"o}rg, Christina and Meissburger, Bettina and Wolf, Stephan and Penzel, Roland and Herpel, Esther and Kirchner, Martina and Lier, Amelie and Endris, Volker and Singer, Stephan and Schirmacher, Peter and Stenzinger, Albrecht and Schlenk, Richard Friedrich and Brors, Benedikt and Kalle, Christof von and Glimm, Hanno and Fr{\"o}hling, Stefan}, title={Precision oncology based on omics data}, subtitle={the NCT Heidelberg experience}, year={2017}, pages={877-886}, language={eng}, issn={1097-0215}, volume={141}, number={5}, note={Gesehen am 04.09.2018}, journal={International journal of cancer}, doi={10.1002/ijc.30828}, } @article{UBHD-68588678, author={Horak, Peter and Weischenfeldt, Joachim and Amsberg, Gunhild von and Beyer, Burkhard and Sch{\"u}tte, Andreas and Uhrig, Sebastian and Gieldon, Laura and Klink, Barbara and Feuerbach, Lars and H{\"u}bschmann, Daniel and Kreutzfeldt, Simon and Heining, Christoph and Maier, Sebastian and Hutter, Barbara and Penzel, Roland and Schlesner, Matthias and Eils, Roland and Sauter, Guido and Stenzinger, Albrecht and Brors, Benedikt and Schr{\"o}ck, Evelin and Glimm, Hanno and Fr{\"o}hling, Stefan and Schlomm, Thorsten}, title={Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance}, year={2019}, pages={10 S.}, language={eng}, issn={2373-2873}, volume={5(2019}, note={Gesehen am 18.06.2020}, journal={Cold Spring Harbor molecular case studies}, doi={10.1101/mcs.a003657}, } @article{UBHD-68460155, author={Kordes, Maximilian and Heining, Christoph and Hutter, Barbara and Richter, Daniela and Ge{\"o}rg, Christina and Scholl, Claudia and Gr{\"o}schel, Stefan and Roth, Wilfried and Kalle, Christof von and J{\"a}ger, Dirk and Brors, Benedikt and Weichert, Wilko and Gr{\"u}llich, Carsten and Glimm, Hanno and Fr{\"o}hling, Stefan}, title={Cooperation of BRAF F595L and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling}, year={2016}, pages={937-946}, language={eng}, issn={1476-5551}, volume={30}, number={4}, note={Advance online publication, 18 December 2015 ; Gesehen am 26.11.2019}, journal={Leukemia}, doi={10.1038/leu.2015.319}, } @article{UBHD-69143062, author={Lauinger, Manuel and Christen, Daniel and Klar, Rhena F. U. and Roubaty, Carole and Heilig, Christoph E. and Stumpe, Michael and Knox, Jennifer J. and Radulovich, Nikolina and Tamblyn, Laura and Xie, Irene Y. and Horak, Peter and Forschner, Andrea and Bitzer, Michael and Wittel, Uwe Alexander and B{\"o}rries, Melanie and Ball, Claudia R. and Heining, Christoph and Glimm, Hanno and Fr{\"o}hlich, Martina and H{\"u}bschmann, Daniel and Gallinger, Steven and Fritsch, Ralph and Fr{\"o}hling, Stefan and O’Kane, Grainne M. and Dengjel, J{\"o}rn and Brummer, Tilman}, title={BRAFΔβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability}, year={2023}, pages={1-22}, language={eng}, issn={2375-2548}, volume={9}, note={Ver{\"o}ffentlicht: 1. September 2023 ; Gesehen am 15.11.2023 ; Der Ausdruck "Δβ3-αC" ist im Titel hochgestellt}, journal={Science advances}, doi={10.1126/sciadv.ade7486}, } @article{UBHD-68447463, author={Leichsenring, Jonas and Horak, Peter and Heining, Christoph and Christopoulos, Petros and Volckmar, Anna-Lena and Neumann, Olaf and Kirchner, Martina and Budczies, Jan and Heilig, Christoph E. and Kazdal, Daniel and Allg{\"a}uer, Michael and Harms, Alexander and Rempel, Eugen and Thomas, Michael and Longerich, Thomas and Schirmacher, Peter and Penzel, Roland and Endris, Volker and Fr{\"o}hling, Stefan and Stenzinger, Albrecht}, title={Variant classification in precision oncology}, year={2019}, pages={2996-3010}, language={eng}, issn={1097-0215}, volume={145}, number={11}, note={Gesehen am 29.10.2019}, journal={International journal of cancer}, doi={10.1002/ijc.32358}, } @article{UBHD-68563771, author={Mock, Andreas and Heilig, Christoph E. and Kreutzfeldt, Simon and H{\"u}bschmann, Daniel and Heining, Christoph and Schr{\"o}k, Evelin and Brors, Benedikt and Stenzinger, Albrecht and J{\"a}ger, Dirk and Schlenk, Richard Friedrich and Glimm, Hanno and Fr{\"o}hling, Stefan and Horak, Peter and Griesinger, Frank}, title={Community-driven development of a modified progression-free survival ratio for precision oncology}, year={2019}, pages={6 S.}, language={eng}, issn={2059-7029}, volume={4(2019) Artikel-Nummer e00058}, number={6 Seiten}, note={Gesehen am 14.04.2020}, journal={ESMO open}, doi={10.1136/esmoopen-2019-000583}, } @article{UBHD-68957380, author={M{\"o}hrmann, Lino and Werner, Maximilian and Oleś, Małgorzata and Mock, Andreas and Uhrig, Sebastian and Jahn, Arne and Kreutzfeldt, Simon and Fr{\"o}hlich, Martina and Hutter, Barbara and Paramasivam, Nagarajan and Richter, Daniela and Beck, Katja and Winter, Ulrike and Pf{\"u}tze, Katrin and Heilig, Christoph E. and Teleanu, Maria-Veronica and Lipka, Daniel and Zapatka, Marc and Hanf, Dorothea and List, Catrin and Allg{\"a}uer, Michael and Penzel, Roland and R{\"u}ter, Gina and Jelas, Ivan and Hamacher, Rainer W. and Falkenhorst, Johanna and Wagner, Sebastian and Brandts, Christian H. and B{\"o}rries, Melanie and Illert, Anna Lena and Metzeler, Klaus H. and Westphalen, C. Benedikt and Desuki, Alexander and Kindler, Thomas and Folprecht, Gunnar and Weichert, Wilko and Brors, Benedikt and Stenzinger, Albrecht and Schr{\"o}ck, Evelin and H{\"u}bschmann, Daniel and Horak, Peter and Heining, Christoph and Fr{\"o}hling, Stefan and Glimm, Hanno}, title={Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity}, year={2022}, pages={1-15}, language={eng}, issn={2041-1723}, volume={13}, number={Artikel-ID 4485}, note={Gesehen am 25.08.2022}, journal={Nature Communications}, doi={10.1038/s41467-022-31866-4}, } @article{UBHD-68568600, author={Perera-Bel, Júlia and Hutter, Barbara and Heining, Christoph and Fr{\"o}hlich, Martina and Fr{\"o}hling, Stefan and Glimm, Hanno and Brors, Benedikt}, title={From somatic variants towards precision oncology}, subtitle={evidence-driven reporting of treatment options in molecular tumor boards}, year={2018}, pages={15 S.}, language={eng}, issn={1756-994X}, volume={10(2018) Artikel-Nummer 18}, number={15 Seiten}, note={Gesehen am 21.04.2020}, journal={Genome medicine}, doi={10.1186/s13073-018-0529-2}, } @article{UBHD-68495264, author={Ronellenfitsch, Michael Wilfried and Harter, Patrick N. and Kirchner, Martina and Heining, Christoph and Hutter, Barbara and Gieldon, Laura and Schittenhelm, Jens Florian and Schuhmann, Martin U. and Tatagiba, Marcos and Marquardt, Gerhard and Wagner, Marlies and Endris, Volker and Brandts, Christian H. and Mautner, Victor-Felix and Schr{\"o}ck, Evelin and Weichert, Wilko and Brors, Benedikt and Deimling, Andreas von and Mittelbronn, Michel and Steinbach, Joachim P. and Reuss, David and Glimm, Hanno and Stenzinger, Albrecht and Fr{\"o}hling, Stefan}, title={Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors}, year={2020}, pages={2488-2495}, language={eng}, issn={1558-8238}, volume={130}, number={5}, note={First published February 4, 2020 ; Gesehen am 02.032020}, journal={The journal of clinical investigation}, doi={10.1172/JCI130787}, } @article{UBHD-68647801, author={Voronina, Natalia and Wong, John K. L. and H{\"u}bschmann, Daniel and Hlevnjak, Mario and Uhrig, Sebastian and Heilig, Christoph E. and Horak, Peter and Kreutzfeldt, Simon and Mock, Andreas and Stenzinger, Albrecht and Hutter, Barbara and Fr{\"o}hlich, Martina and Brors, Benedikt and Jahn, Arne and Klink, Barbara and Gieldon, Laura and Sieverling, Lina Katharine and Feuerbach, Lars and Chudasama, Priya and Beck, Katja and Kroiss, Matthias and Heining, Christoph and M{\"o}hrmann, Lino and Fischer, Andrea and Schr{\"o}ck, Evelin and Glimm, Hanno and Zapatka, Marc and Lichter, Peter and Fr{\"o}hling, Stefan and Ernst, Aurélie}, title={The landscape of chromothripsis across adult cancer types}, year={2020}, pages={13 S.}, language={eng}, issn={2041-1723}, volume={11(2020) Artikel-Nummer 2320}, number={13 Seiten}, note={Gesehen am 13.10.2020}, journal={Nature Communications}, doi={10.1038/s41467-020-16134-7}, }