@article{UBHD-68409806, author={Brabetz, Sebastian and Korshunov, Andrey and Balasubramanian, Gnana Prakash and Chavez, Lukas and Jones, David T. W. and Pfister, Stefan and Kool, Marcel}, title={A biobank of patient-derived pediatric brain tumor models}, year={2018}, pages={1752-1761}, language={eng}, issn={1546-170X}, volume={24}, number={11}, note={Gesehen am 18.07.2019}, journal={Nature medicine}, doi={10.1038/s41591-018-0207-3}, } @article{UBHD-68746998, author={Ecker, Jonas and Thatikonda, Venu and Sigismondo, Gianluca and Selt, Florian and Valinciute, Gintvile and Oehme, Ina and M{\"u}ller, Carina and Buhl, Juliane and Ridinger, Johannes and Usta, Diren and Qin, Nan and Tilburg, Cornelis M. van and Herold-Mende, Christel and Remke, Marc and Sahm, Felix and Westermann, Frank and Kool, Marcel and Wechsler-Reya, Robert J. and Chavez, Lukas and Krijgsveld, Jeroen and J{\"a}ger, Natalie and Pfister, Stefan and Witt, Olaf and Milde, Till}, title={Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma}, year={2021}, pages={226-239}, language={eng}, issn={1523-5866}, volume={23}, number={2 vom: Feb.}, note={Gesehen am 10.06.2021 ; First published: 21 August 2020}, journal={Neuro-Oncology}, doi={10.1093/neuonc/noaa191}, } @article{UBHD-68377942, author={Erkek, Serap and Johann, Pascal-David and Zapatka, Marc and Sturm, Dominik and Jones, David T. W. and Korshunov, Andrey and Wolf, Stephan and Mallm, Jan-Philipp and Witt, Olaf and Kulozik, Andreas and Korbel, Jan Oliver and Lichter, Peter and Eils, Roland and Chavez, Lukas and Pfister, Stefan and Kool, Marcel}, editor={Northcott, Michael}, title={Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation}, year={2019}, pages={25 S.}, language={eng}, issn={1878-3686}, volume={35(2019}, note={Available online 27 December 2018 ; Gesehen am 08.05.2019}, journal={Cancer cell}, doi={10.1016/j.ccell.2018.11.014}, } @article{UBHD-68564560, author={Forget, Antoine and Brabetz, Sebastian and Sieber, Laura and Chavez, Lukas and Okonechnikov, Konstantin and Sharma, Tanvi and Thatikonda, Venu and Korshunov, Andrey and Kool, Marcel and Pfister, Stefan and Kawauchi, Daisuke}, title={Aberrant ERBB4-SRC signaling as a hallmark of group 4 medulloblastoma revealed by integrative phosphoproteomic profiling}, year={2018}, pages={24 S.}, language={eng}, issn={1878-3686}, volume={34(2018}, note={Gesehen am 15.04.2020}, journal={Cancer cell}, doi={10.1016/j.ccell.2018.08.002}, } @article{UBHD-68306118, author={Gojo, Johannes and Pajtler, Kristian Wilfried and Hovestadt, Volker and Chavez, Lukas and Korshunov, Andrey and Pfister, Stefan and Kool, Marcel}, title={Telomerase activation in posterior fossa group a ependymomas is associated with dismal prognosis and chromosome 1q gain}, year={2017}, pages={1183-1194}, language={eng}, issn={1523-5866}, volume={19}, number={9}, note={Gesehen am 19.09.2018}, journal={Neuro-Oncology}, doi={10.1093/neuonc/nox027}, } @article{UBHD-68436251, author={Huang, Miller and Chavez, Lukas and Reiners-Koch, Philipp-Sebastian and Kool, Marcel and Pfister, Stefan}, title={Engineering genetic predisposition in human neuroepithelial stem cells recapitulates medulloblastoma tumorigenesis}, year={2019}, pages={433-446.e7}, language={eng}, issn={1875-9777}, volume={25}, number={3}, note={Gesehen am 08.10.2019}, journal={Cell stem cell}, doi={10.1016/j.stem.2019.05.013}, } @article{UBHD-68313290, author={Huse, Jason T. and Jones, David T. W. and Capper, David and Chavez, Lukas}, title={Polymorphous low-grade neuroepithelial tumor of the young (PLNTY)}, subtitle={an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway}, year={2017}, pages={417-429}, language={eng}, issn={1432-0533}, volume={133}, number={3}, note={Published online: 3 November 2016 ; im Zusatz zum HST ist die Zahl "34" tiefgestellt ; Gesehen am 09.10.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-016-1639-9}, } @article{UBHD-68332967, author={Hwang, Eugene and Kool, Marcel and Capper, David and Chavez, Lukas and Deimling, Andreas von and Jones, David T. W. and Pfister, Stefan and Brabetz, Sebastian}, title={Extensive molecular and clinical heterogeneity in patients with histologically diagnosed cns-pnet treated as a single entity}, subtitle={a report from the children’s oncology group randomized ACNS0332 trial}, year={2018}, pages={3388-3395}, language={eng}, issn={1527-7755}, volume={36}, number={34}, note={Gesehen am 27.11.2018}, journal={Journal of clinical oncology}, doi={10.1200/JCO.2017.76.4720}, } @article{UBHD-68320609, author={Korshunov, Andrey and Chavez, Lukas and Sharma, Tanvi and Jones, David T. W. and Deimling, Andreas von and Pfister, Stefan and Kool, Marcel}, title={DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma}, year={2017}, pages={965-967}, language={eng}, issn={1432-0533}, volume={134}, number={6}, note={Gesehen am 24.10.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-017-1776-9}, } @article{UBHD-68320623, author={Korshunov, Andrey and Chavez, Lukas and Schrimpf, Daniel and Stichel, Damian and Capper, David and Sturm, Dominik and Kool, Marcel and Habel, Antje and Lichter, Peter and Pfister, Stefan and Jones, David T. W. and Deimling, Andreas von}, title={Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis}, year={2018}, pages={656-662}, language={eng}, issn={1750-3639}, volume={28}, number={5}, note={First published: 09 October 2017 ; Gesehen am 22.01.2020}, journal={Brain pathology}, doi={10.1111/bpa.12566}, } @article{UBHD-68431123, author={Korshunov, Andrey and Casalini, Belén and Chavez, Lukas and Hielscher, Thomas and Sill, Martin and Schrimpf, Daniel and Stichel, Damian and Capper, David and Sturm, Dominik and Lichter, Peter and Herold-Mende, Christel and Wick, Wolfgang and Pfister, Stefan and Kool, Marcel and Jones, David T. W. and Deimling, Andreas von and Sahm, Felix}, title={Integrated molecular characterization of IDH-mutant glioblastomas}, year={2019}, pages={108-118}, language={eng}, issn={1365-2990}, volume={45}, number={2}, note={First published: 16 October 2018 ; Gesehen am 18.09.2019}, journal={Neuropathology & applied neurobiology}, doi={10.1111/nan.12523}, } @article{UBHD-68458669, author={Lin, Charles Y. and Zapatka, Marc and Jones, Barbara Christine and Jones, David T. W. and Kool, Marcel and Buchhalter, Ivo and Johann, Pascal-David and Chavez, Lukas and Gr{\"o}schel, Stefan and Eils, Roland and Lichter, Peter and Pfister, Stefan and Kawauchi, Daisuke and Korbel, Jan Oliver}, title={Active medulloblastoma enhancers reveal subgroup-specific cellular origins}, year={2016}, pages={57-62}, language={eng}, issn={1476-4687}, volume={530}, number={7588}, note={Gesehen am 21.11.2019}, journal={Nature}, doi={10.1038/nature16546}, } @article{UBHD-68289802, author={Mack, Stephen C. and Pajtler, Kristian Wilfried and Chavez, Lukas and Okonechnikov, Konstantin and Erkek, Serap and Zapatka, Marc and Milde, Till and Witt, Hendrik and Jones, David T. W. and Lichter, Peter and Korshunov, Andrey and Pfister, Stefan and Kool, Marcel}, title={Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling}, year={2018}, pages={101-105}, language={eng}, issn={1476-4687}, volume={553}, number={7686}, note={Published 20 December 2017 ; Published online 20 December 2017 ; Gesehen am 27.07.2018}, journal={Nature}, doi={10.1038/nature25169}, } @article{UBHD-68292494, author={Neumann, Julia and Wefers, Annika K. and Korshunov, Andrey and Chavez, Lukas and Kool, Marcel}, title={A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-Hedgehog inhibitors}, year={2017}, pages={1191-1202}, language={eng}, issn={1546-170X}, volume={23}, number={10}, note={Gesehen am 06.08.2018}, journal={Nature medicine}, doi={10.1038/nm.4402}, } @article{UBHD-68496117, author={Pajtler, Kristian Wilfried and Sill, Martin and Chavez, Lukas and Witt, Hendrik and Jones, David T. W. and Pfister, Stefan and Kool, Marcel}, title={Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas}, year={2018}, pages={211-226}, language={eng}, issn={1432-0533}, volume={136}, number={2}, note={Gesehen am 03.03.2020}, journal={Acta neuropathologica}, doi={10.1007/s00401-018-1877-0}, } @article{UBHD-68480819, author={Sharma, Tanvi and Schwalbe, Edward C. and Williamson, Daniel and Sill, Martin and Hovestadt, Volker and Mynarek, Martin and Rutkowski, Stefan and Robinson, Giles W. and Gajjar, Amar and Cavalli, Florence M. G. and Ramaswamy, Vijay and Taylor, Michael D. and Lindsey, Janet C. and Hill, Rebecca M. and J{\"a}ger, Natalie and Korshunov, Andrey and Hicks, Debbie and Bailey, Simon and Kool, Marcel and Chavez, Lukas and Northcott, Paul A. and Pfister, Stefan and Clifford, Steven C.}, title={Second-generation molecular subgrouping of medulloblastoma}, subtitle={an international meta-analysis of Group 3 and Group 4 subtypes}, year={2019}, pages={309-326}, language={eng}, issn={1432-0533}, volume={138}, number={2}, note={Gesehen am 27.01.2020}, journal={Acta neuropathologica}, doi={10.1007/s00401-019-02020-0}, } @article{UBHD-68468701, author={Snuderl, Matija and Kannan, Kasthuri and Pfaff, Elke and Wang, Shiyang and Stafford, James M. and Serrano, Jonathan and Heguy, Adriana and Ray, Karina and Faustin, Arline and Aminova, Olga and Dolgalev, Igor and Stapleton, Stacie L. and Zagzag, David and Chiriboga, Luis and Gardner, Sharon L. and Wisoff, Jeffrey H. and Golfinos, John G. and Capper, David and Hovestadt, Volker and Rosenblum, Marc K. and Placantonakis, Dimitris G. and LeBoeuf, Sarah E. and Papagiannakopoulos, Thales Y. and Chavez, Lukas and Ahsan, Sama and Eberhart, Charles G. and Pfister, Stefan and Jones, David T. W. and Karajannis, Matthias A.}, title={Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma}, year={2018}, pages={10 S.}, language={eng}, issn={2041-1723}, volume={9(2018) Artikel-Nummer 2868}, number={10 Seiten}, note={Gesehen am 17.12.2019}, journal={Nature Communications}, doi={10.1038/s41467-018-05029-3}, } @article{UBHD-68384310, author={Wang, Anthony C. and Jones, David T. W. and Chavez, Lukas and Capper, David and Korshunov, Andrey}, title={Desmoplastic infantile ganglioglioma/astrocytoma (DIG/DIA) are distinct entities with frequent BRAFV600 mutations}, year={2018}, pages={1491-1498}, language={eng}, issn={1557-3125}, volume={16}, number={10}, note={Gesehen am 03.05.2019}, journal={Molecular cancer research}, doi={10.1158/1541-7786.MCR-17-0507}, }