@article{UBHD-69270146, author={Cirrincione, Anthony and Poos, Alexandra and Ziccheddu, Bachisio and Kaddoura, Marcella and B{\"a}rtsch, Marc-Andrea and Maclachlan, Kylee and Chojnacka, Monika and Diamond, Benjamin and John, Lukas and Reichert, Philipp and Huhn, Stefanie and Blaney, Patrick and Gagler, Dylan and Rippe, Karsten and Zhang, Yanming and Dogan, Ahmet and Lesokhin, Alexander M. and Davies, Faith and Goldschmidt, Hartmut and Fenk, Roland and Weisel, Katja C. and Mai, Elias K. and Korde, Neha and Morgan, Gareth J. and Usmani, Saad and Landgren, Ola and Raab, Marc-Steffen and Weinhold, Niels and Maura, Francesco}, title={The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma}, year={2024}, pages={771-783}, language={eng}, issn={1528-0020}, volume={144}, number={7 vom: Aug.}, note={Gesehen am 06.11.2024}, journal={Blood}, doi={10.1182/blood.2024024299}, } @article{UBHD-69007734, author={Darawshi, Odai and Muz, Barbara and Naamat, Shiri Gershon and Praveen, Bellam and Mahameed, Mohamed and Goldberg, Karin and Dipta, Priya and Shmuel, Miriam and Forno, Francesca and Boukeileh, Shatha and Pahima, Hadas and Hermann, Julia and Raab, Marc-Steffen and Poos, Alexandra and Weinhold, Niels and Rosenbluh, Chaggai and Gatt, Moshe E. and Palm, Wilhelm and Azab, Abdel Kareem and Tirosh, Boaz}, title={An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma}, year={2022}, pages={1-12}, language={eng}, issn={2041-4889}, volume={13}, note={Gesehen am 18.01.2023}, journal={Cell death & disease}, doi={10.1038/s41419-022-05421-4}, } @article{UBHD-69085845, author={Giesen, Nicola and Chatterjee, Manik and Scheid, Christof and Poos, Alexandra and Besemer, Britta and Miah, Kaya and Benner, Axel and Becker, Nicole and Moehler, Thomas and Metzler, Ivana and Khandanpour, Cyrus and Seidel-Gl{\"a}tzer, Andrea and Trautmann-Grill, Karolin and Kort{\"u}m, K. Martin and M{\"u}ller-Tidow, Carsten and Mechtersheimer, Gunhild and Goeppert, Benjamin and Stenzinger, Albrecht and Weinhold, Niels and Goldschmidt, Hartmut and Weisel, Katja and Raab, Marc-Steffen}, title={A phase 2 clinical trial of combined BRAF/MEK inhibition for BRAFV600E-mutated multiple myeloma}, year={2023}, pages={1685-1690}, language={eng}, issn={1528-0020}, volume={141}, number={14 vom: Apr.}, note={Gesehen am 15.06.2023}, journal={Blood}, doi={10.1182/blood.2022017789}, } @article{UBHD-68949410, author={Heinemann, Luca and M{\"o}llers, Klara Maria and Ahmed, Helal Mohammed Mohammed and Wei, Lanying and Sun, Kaiyan and Nimmagadda, Subbaiah Chary and Frank, Daria and Baumann, Anja and Poos, Alexandra and Dugas, Martin and Varghese, Julian and Raab, Marc-Steffen and Khandanpour, Cyrus}, title={Inhibiting PI3K-AKT-mTOR signaling in multiple myeloma-associated mesenchymal stem cells impedes the proliferation of multiple myeloma cells}, year={2022}, pages={1-11}, language={eng}, issn={2234-943X}, volume={12}, number={Artikel-ID 874325}, note={Gesehen am 02.08.2022}, journal={Frontiers in oncology}, doi={10.3389/fonc.2022.874325}, } @article{UBHD-68676126, author={H{\"o}flmayer, Doris and Poos, Alexandra and Rippe, Karsten}, title={Expression of CCCTC-binding factor (CTCF) is linked to poor prognosis in prostate cancer}, year={2020}, pages={129-138}, language={eng}, issn={1878-0261}, volume={14}, number={1}, note={Gesehen am 23.12.2020 ; Available online: 29 November 2019}, journal={Molecular oncology}, doi={10.1002/1878-0261.12597}, } @article{UBHD-69159435, author={John, Lukas and Poos, Alexandra and Brobeil, Alexander and Schinke, Carolina and Huhn, Stefanie and Prokoph, Nina and Lutz, Raphael and Wagner, Barbara and Zangari, Maurizio and Tirier, Stephan Marius and Mallm, Jan-Philipp and Schumacher, Sabrina and Vonficht, Dominik and Solé-Boldo, Llorenç and Quick, Sabine and Steiger, Simon and Przybilla, Moritz Jakob and Bauer, Katharina and Baumann, Anja and Hemmer, Stefan and Rehnitz, Christoph and L{\"u}ckerath, Christian and Sachpekidis, Christos and Mechtersheimer, Gunhild and Haberkorn, Uwe and Dimitrakopoulou-Strauss, Antonia and Reichert, Philipp and Barlogie, Bart and M{\"u}ller-Tidow, Carsten and Goldschmidt, Hartmut and Hillengaß, Jens and Rasche, Leo and Haas, Simon and Van Rhee, Frits and Rippe, Karsten and Raab, Marc-Steffen and Sauer, Sandra and Weinhold, Niels}, title={Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level}, year={2023}, pages={1-17}, language={eng}, issn={2041-1723}, volume={14}, number={Artikel-ID 5011}, note={Gesehen am 09.01.2024}, journal={Nature Communications}, doi={10.1038/s41467-023-40584-4}, } @article{UBHD-69051075, author={Mai, Elias K. and Huhn, Stefanie and Miah, Kaya and Poos, Alexandra and Scheid, Christoph and Weisel, Katja and Bertsch, Uta and Munder, Markus and Berlanga, Oscar and Hose, Dirk and Seckinger, Anja and Jauch, Anna and Blau, Igor-Wolfgang and H{\"a}nel, Mathias and Salwender, Hans and Benner, Axel and Raab, Marc-Steffen and Goldschmidt, Hartmut and Weinhold, Niels}, title={Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma}, year={2023}, pages={1-9}, language={eng}, issn={2044-5385}, volume={13}, note={Gesehen am 13.03.2023}, journal={Blood cancer journal}, doi={10.1038/s41408-022-00772-9}, url={https://doi.org/10.1038/s41408-022-00772-9}, library={UB}, } @article{UBHD-68412232, author={Mallm, Jan-Philipp and ̇Iskar, Murat and Klett, Lara C. and Poos, Alexandra and Erdel, Fabian and Tavernari, Daniele and Schumacher, Sabrina and Brors, Benedikt and Lichter, Peter and Zapatka, Marc and Rippe, Karsten}, title={Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks}, year={2019}, pages={20 S.}, language={eng}, issn={1744-4292}, volume={15(2019}, note={Gesehen am 25.07.2019}, journal={Molecular systems biology}, doi={10.15252/msb.20188339}, } @article{UBHD-69281478, author={Maura, Francesco and Rajanna, Arjun Raj and Ziccheddu, Bachisio and Poos, Alexandra and Derkach, Andriy and Maclachlan, Kylee and Durante, Michael and Diamond, Benjamin and Papadimitriou, Marios and Davies, Faith and Boyle, Eileen M. and Walker, Brian and Hultcrantz, Malin and Silva, Ariosto and Hampton, Oliver and Teer, Jamie K. and Siegel, Erin M. and Bolli, Niccolò and Jackson, Graham H. and Kaiser, Martin and Pawlyn, Charlotte and Cook, Gordon and Kazandjian, Dickran and Stein, Caleb and Chesi, Marta and Bergsagel, Leif and Mai, Elias K. and Goldschmidt, Hartmut and Weisel, Katja C. and Fenk, Roland and Raab, Marc-Steffen and Van Rhee, Fritz and Usmani, Saad and Shain, Kenneth H. and Weinhold, Niels and Morgan, Gareth and Landgren, Ola}, title={Genomic classification and individualized prognosis in multiple myeloma}, year={2024}, pages={1229-1240}, language={eng}, issn={1527-7755}, volume={42}, number={11 vom: Apr.}, note={Gesehen am 09.12.2024}, journal={Journal of clinical oncology}, doi={10.1200/JCO.23.01277}, } @article{UBHD-68360069, author={Minner, Sarah and Poos, Alexandra and Rippe, Karsten}, title={Loss of CCAAT-enhancer-binding protein alpha (CEBPA) is linked to poor prognosis in PTEN deleted and TMPRSS2}, subtitle={ERG fusion type prostate cancers}, year={2019}, pages={302-311}, language={eng}, issn={1097-0045}, volume={79}, number={3}, note={First published: 14 November 2018 ; Gesehen am 18.02.2019 ; Im Titel sind "PTEN", "TMPRSS2" und "ERG" kursiv geschrieben}, journal={The prostate}, doi={10.1002/pros.23736}, } @book{UBHD-68557343, author={Poos, Alexandra}, title={Mixed integer linear programming based approaches to study telomere maintenance mechanisms}, address={Heidelberg}, year={2019}, pages={1 Online-Ressource (xxi, 112, XL Seiten)}, language={eng}, school={Dissertation, Ruperto Carola University Heidelberg, 2019}, doi={10.11588/heidok.00026499}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-264991}, library={UB}, } @book{UBHD-68424833, author={Poos, Alexandra}, organization={Universit{\"a}t Heidelberg}, title={Mixed Integer Linear Programming based approaches to study telomere meintenance mechanisms}, address={Heidelberg}, year={2019}, pages={xxi, 112, XL Seiten}, language={eng}, school={Dissertation, Ruperto Carola University Heidelberg, 2019}, library={UB [Signatur: 2019 U 665]}, } @article{UBHD-68656941, author={Poos, Alexandra and Maicher, André and Dieckmann, Anna Katharina and Oswald, Marcus and Eils, Roland and Kupiec, Martin and Luke, Brian and K{\"o}nig, Rainer}, title={Mixed integer linear programming based machine learning approach identifies regulators of telomerase in yeast}, year={2016}, pages={9 S.}, language={eng}, issn={1362-4962}, volume={44(2016}, note={Published online 22 February 2016 ; Gesehen am 03.11.2020}, journal={Nucleic acids research}, doi={10.1093/nar/gkw111}, } @article{UBHD-68561094, author={Poos, Alexandra and Kordaß, Theresa and Kolte, Amol and Ast, Volker and Oswald, Marcus and Rippe, Karsten and K{\"o}nig, Rainer}, title={Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach}, year={2019}, language={eng}, issn={1471-2105}, volume={20(2019) Artikel-Nummer 737}, number={12 Seiten}, note={Gesehen am 03.04.2020}, journal={BMC bioinformatics}, doi={10.1186/s12859-019-3323-2}, } @article{UBHD-68904220, author={Poos, Alexandra and Schroeder, Cornelia and Jaishankar, Neeraja and R{\"o}ll, Daniela and Oswald, Marcus and Meiners, Jan and Braun, Delia and Knotz, Caroline and Frank, Lukas and Gunkel, Manuel and Spilger, Roman and Wollmann, Thomas and Polonski, Adam and Makrypidi-Fraune, Georgia and Fraune, Christoph and Graefen, Markus and Chung, Inn and Stenzel, Alexander and Erfle, Holger and Rohr, Karl and Baniahmad, Aria and Sauter, Guido and Rippe, Karsten and Simon, Ronald and K{\"o}nig, Rainer}, title={PITX1 is a regulator of TERT expression in prostate cancer with prognostic power}, year={2022}, pages={-23}, language={eng}, issn={2072-6694}, volume={14}, note={Gesehen am 06.04.2022}, journal={Cancers}, doi={10.3390/cancers14051267}, } @article{UBHD-69146494, author={Poos, Alexandra and Prokoph, Nina and Przybilla, Moritz Jakob and Mallm, Jan-Philipp and Steiger, Simon and Seufert, Isabelle and John, Lukas and Tirier, Stephan Marius and Bauer, Katharina and Baumann, Anja and Rohleder, Jennifer and Munawar, Umair and Rasche, Leo and Kort{\"u}m, K. Martin and Giesen, Nicola and Reichert, Philipp and Huhn, Stefanie and M{\"u}ller-Tidow, Carsten and Goldschmidt, Hartmut and Stegle, Oliver and Raab, Marc-Steffen and Rippe, Karsten and Weinhold, Niels}, title={Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis}, year={2023}, pages={1633-1646}, language={eng}, issn={1528-0020}, volume={142}, number={19}, note={Gesehen am 27.11.2023}, journal={Blood}, doi={10.1182/blood.2023019758}, } @article{UBHD-68959497, author={Rasche, Leo and Schinke, Carolina and Maura, Francesco and Bauer, Michael A. and Ashby, Cody and Deshpande, Shayu and Poos, Alexandra and Zangari, Maurizio and Thanendrarajan, Sharmilan and Davies, Faith E. and Walker, Brian A. and Barlogie, Bart and Landgren, Ola and Morgan, Gareth J. and van Rhee, Frits and Weinhold, Niels}, title={The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states}, year={2022}, pages={1-13}, language={eng}, issn={2041-1723}, volume={13}, number={Artikel-ID 4517}, note={Gesehen am 01.09.2022}, journal={Nature Communications}, doi={10.1038/s41467-022-32145-y}, url={https://doi.org/10.1038/s41467-022-32145-y}, library={UB}, } @article{UBHD-69068324, author={Schinke, Carolina and Poos, Alexandra and Bauer, Michael and John, Lukas and Johnson, Sarah and Deshpande, Shayu and Carrillo, Luis and Alapat, Daisy and Rasche, Leo and Thanendrarajan, Sharmilan and Zangari, Maurizio and Al Hadidi, Samer and Van Rhee, Frits and Davies, Faith and Raab, Marc-Steffen and Morgan, Gareth and Weinhold, Niels}, title={Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level}, year={2022}, pages={5873-5883}, language={eng}, issn={2473-9537}, volume={6}, number={22}, note={Gesehen am 24.04.2023}, journal={Blood advances}, doi={10.1182/bloodadvances.2022007217}, } @article{UBHD-69197571, author={Schreiner, Sarah and Berghaus, Natalie and Poos, Alexandra and Raab, Marc-Steffen and Besemer, Britta and Fenk, Roland and Goldschmidt, Hartmut and Mai, Elias K. and M{\"u}ller-Tidow, Carsten and Weinhold, Niels and Hegenbart, Ute and Huhn, Stefanie and Sch{\"o}nland, Stefan}, title={Sequence diversity of kappa light chains from patients with AL amyloidosis and multiple myeloma}, year={2024}, pages={86-94}, language={eng}, issn={1744-2818}, volume={31}, number={2}, note={Gesehen am 04.04.2024}, journal={Amyloid}, doi={10.1080/13506129.2023.2295221}, } @article{UBHD-68807760, author={Tirier, Stephan Marius and Mallm, Jan-Philipp and Steiger, Simon and Poos, Alexandra and Awwad, Mohamed and Giesen, Nicola and Casiraghi, Nicola and Susak, Hana and Bauer, Katharina and Baumann, Anja and John, Lukas and Seckinger, Anja and Hose, Dirk and M{\"u}ller-Tidow, Carsten and Goldschmidt, Hartmut and Stegle, Oliver and Hundemer, Michael and Weinhold, Niels and Raab, Marc-Steffen and Rippe, Karsten}, title={Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics}, year={2021}, pages={1-16}, language={eng}, issn={2041-1723}, volume={12}, number={Artikel-ID 6960}, note={Gesehen am 03.12.2021}, journal={Nature Communications}, doi={10.1038/s41467-021-26951-z}, } @article{UBHD-69149698, author={Zhao, Duoduo and Rohde, Christian and G{\"o}llner, Stefanie and Zhou, Fengbiao and Pauli, Cornelius and Blank, Maximilian Felix and Zinz, Rafael and Grab, Anna Luise and Poos, Alexandra and John, Lukas and Huhn, Stefanie and Raab, Marc-Steffen and M{\"u}ller-Tidow, Carsten and Weinhold, Niels}, title={The landscape of small nucleolar RNA expression in multiple myeloma is determined by cytogenetic alterations}, year={2023}, pages={2526-2531}, language={eng}, issn={1476-5551}, volume={37}, note={Gesehen am 05.12.2023}, journal={Leukemia}, doi={10.1038/s41375-023-02060-2}, }