@article{UBHD-68466773, author={Abu Sammour, Denis and Marsching, Christian and Geisel, Alexander and Erich, Katrin and Schulz, Sandra and Ramallo Guevara, Carina and Rabe, Jan-Hinrich and Marx, Alexander and Findeisen, Peter and Hohenberger, Peter and Hopf, Carsten}, title={Quantitative mass spectrometry imaging reveals mutation status-independent lack of imatinib in liver metastases of gastrointestinal stromal tumors}, year={2019}, pages={9 S.}, language={eng}, issn={2045-2322}, volume={9(2019) Artikel-Nummer 10698}, number={9 Seiten}, note={Gesehen am 11.12.2019}, journal={Scientific reports}, doi={10.1038/s41598-019-47089-5}, } @article{UBHD-69321434, author={Cairns, James L. and Huber, Johanna and Lewen, Andrea and Jung, Jessica and Maurer, Stefan J. and Bausbacher, Tobias and Schmidt, Stefan and Levkin, Pavel and Sévin, Daniel Charles and G{\"o}pfrich, Kerstin and Koch, Philipp and Kann, Oliver and Hopf, Carsten}, title={Mass-guided single-cell MALDI imaging of low-mass metabolites reveals cellular activation markers}, year={2025}, pages={1-15}, language={eng}, issn={2198-3844}, volume={12}, note={Gesehen am 24.03.2025}, journal={Advanced science}, doi={10.1002/advs.202410506}, } @article{UBHD-69290967, author={Enzlein, Thomas and Lashley, Tammaryn and Sammour, Denis Abu and Hopf, Carsten and Chávez-Gutiérrez, Lucía}, title={Integrative single-plaque analysis reveals signature Aβ and lipid profiles in the Alzheimer’s brain}, year={2024}, pages={9799-9807}, language={eng}, issn={1520-6882}, volume={96}, number={24}, note={Online ver{\"o}ffentlicht: 3. Juni 2024 ; Gesehen am 15.01.2025}, journal={Analytical chemistry}, doi={10.1021/acs.analchem.3c05557}, } @article{UBHD-68295703, author={Erich, Katrin and Marx, Alexander and Hopf, Carsten}, title={Scores for standardization of on-tissue digestion of formalin-fixed paraffin-embedded tissue in MALDI-MS imaging}, year={2017}, pages={907-915}, language={eng}, issn={1878-1454}, volume={1865}, number={7}, note={Gesehen am 15.08.2018 ; Available online 6 September 2016}, journal={Biochimica et biophysica acta}, doi={10.1016/j.bbapap.2016.08.020}, } @article{UBHD-68403640, author={Erich, Katrin and M{\"u}ller, Torsten and Abu Sammour, Denis and Hinsenkamp, Isabel and Gutting, Tobias and Burgermeister, Elke and Findeisen, Peter and Ebert, Matthias and Krijgsveld, Jeroen and Hopf, Carsten}, title={Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI Mass Spectrometry Imaging}, year={2019}, pages={151-161}, language={eng}, issn={1535-9484}, volume={18}, number={1}, note={Gesehen am 02.07.2019}, journal={Molecular & cellular proteomics}, doi={10.1074/mcp.RA118.000980}, } @article{UBHD-67659208, author={F{\"u}l{\"o}p, Annabelle and Hopf, Carsten}, title={4-phenyl-alpha-cyanocinnamic acid amide}, subtitle={screening for a negative ion matrix for MALDI-MS imaging of multiple lipid classes}, year={2013}, pages={9156-9163}, language={eng}, issn={1520-6882}, volume={85}, number={19}, note={Gesehen am: 11.08.2014}, journal={Analytical chemistry}, doi={10.1021/ac4018154}, } @article{UBHD-69004645, author={F{\"u}l{\"o}p, Annabelle and Marsching, Christian and Barka, Frederik and Ucal, Yasemin and Holfelder, Pauline and Opitz, Christiane and Barka, G{\"u}nes and Hopf, Carsten}, title={Device-controlled microcondensation for spatially confined on-tissue digests in MALDI imaging of N-glycans}, year={2022}, pages={1-11}, language={eng}, issn={1424-8247}, volume={15}, note={Gesehen am 11.01.2023 ; This article belongs to the special issue "Mass spectrometry imaging in pharmaceutical research"}, journal={Pharmaceuticals}, doi={10.3390/ph15111356}, } @article{UBHD-68416918, author={F{\"u}l{\"o}p, Annabelle and Hopf, Carsten}, title={Molecular imaging of brain localization of liposomes in mice using MALDI mass spectrometry}, year={2016}, pages={10 S.}, language={eng}, issn={2045-2322}, volume={6(2016) Artikel-Nummer 33791}, number={10 Seiten}, note={Gesehen am 06.08.2019}, journal={Scientific reports}, doi={10.1038/srep33791}, } @article{UBHD-69248917, author={Gaikwad, Manasi and Richter, Florian and G{\"o}tz, Rabea and D{\"o}rrbaum, Aline and Schumacher, Lena and Tonillo, Jason and Frech, Christian and Kellner, Roland and Hopf, Carsten}, title={Site-specific structural changes in long-term-stressed monoclonal antibody revealed with DEPC covalent-labeling and quantitative mass spectrometry}, year={2023}, pages={1-20}, language={eng}, issn={1424-8247}, volume={16}, note={Gesehen am 30.08.2024}, journal={Pharmaceuticals}, doi={10.3390/ph16101418}, } @article{UBHD-68348402, author={Gaißmaier, Tanja and Siebenhaar, Markus and Hopf, Carsten}, title={Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry}, year={2016}, pages={892-901}, language={eng}, issn={1364-5528}, volume={141}, number={3}, note={Gesehen am 16.01.2019}, journal={The analyst}, doi={10.1039/C5AN02302E}, } @article{UBHD-68469820, author={Gerichten, Johanna von and Marsching, Christian and Engel, Robert and Herzer, Silke and Galy, Bruno and Nordstr{\"o}m, Viola and Hopf, Carsten and Gr{\"o}ne, Hermann-Josef and Sandhoff, Roger}, title={Bacterial immunogenic α-galactosylceramide identified in the murine large intestine}, subtitle={dependency on diet and inflammation}, year={2019}, pages={1892-1904}, language={eng}, issn={1539-7262}, volume={60}, number={11}, note={Gesehen am 19.12.2019}, journal={Journal of lipid research}, doi={10.1194/jlr.RA119000236}, } @article{UBHD-68471866, author={Herzer, Silke and Hagan, Cassidy and Gerichten, Johanna von and Dieterle, Vanessa and Munteanu, Bogdan and Sandhoff, Roger and Hopf, Carsten and Nordstr{\"o}m, Viola}, title={Deletion of specific sphingolipids in distinct neurons improves spatial memory in a mouse model of Alzheimer’s Disease}, year={2018}, language={eng}, issn={1662-5099}, volume={11(2018) Artikel-Nummer 206}, number={21 Seiten}, note={Gesehen am 08.01.2020}, journal={Frontiers in molecular neuroscience}, doi={10.3389/fnmol.2018.00206}, } @article{UBHD-69291904, author={Heuer, Sophie and Burghaus, Ina and Gose, Maria and Keßler, Tobias and Sahm, Felix and Vollmuth, Philipp and Venkataramani, Varun and Hoffmann, Dirk C. and Schlesner, Matthias and Ratliff, Miriam and Hopf, Carsten and Herrlinger, Ulrich and Ricklefs, Franz Lennard and Bendszus, Martin and Krieg, Sandro and Wick, Antje and Wick, Wolfgang and Winkler, Frank}, title={PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma}, year={2024}, pages={1-13}, language={eng}, issn={1471-2407}, volume={24}, note={Gesehen am 17.01.2024}, journal={BMC cancer}, doi={10.1186/s12885-024-11846-1}, } @article{UBHD-68424018, author={Hinsenkamp, Isabel and Roscher, Mareike and Sch{\"o}nberg, Stefan and Ebert, Matthias and W{\"a}ngler, Bj{\"o}rn and Hopf, Carsten and Burgermeister, Elke}, title={Inhibition of Rho-associated kinase 1/2 attenuates tumor growth in murine gastric cancer}, year={2016}, pages={500-511}, language={eng}, issn={1476-5586}, volume={18}, number={8}, note={Gesehen am 26.08.2019}, journal={Neoplasia}, doi={10.1016/j.neo.2016.07.002}, } @article{UBHD-69213326, author={Koch, Matthias and Enzlein, Thomas and Chen, Shu‐Yu and Petit, Dieter and Lismont, Sam and Zacharias, Martin and Hopf, Carsten and Chávez‐Gutiérrez, Lucía}, title={APP substrate ectodomain defines amyloid‐β peptide length by restraining γ‐secretase processivity and facilitating product release}, year={2023}, pages={1-19}, language={eng}, issn={1460-2075}, volume={42}, note={Gesehen am 14.05.2024}, journal={The EMBO journal}, doi={10.15252/embj.2023114372}, } @article{UBHD-68445071, author={Ly, Alice and Longuespée, Rémi and Marsching, Christian and Kriegsmann, Katharina and Hopf, Carsten and Schirmacher, Peter and Kriegsmann, Mark}, title={Site-to-site reproducibility and spatial resolution in MALDI-MSI of peptides from formalin-fixed paraffin-embedded samples}, year={2019}, language={eng}, issn={1862-8354}, volume={13(2019}, note={First published: 08 November 2018 ; Gesehen am 24.10.2019}, journal={Proteomics}, doi={10.1002/prca.201800029}, } @article{UBHD-67813509, author={Marsching, Christian and Hopf, Carsten}, title={Quantitative imaging mass spectrometry of renal sulfatides}, subtitle={validation by classical mass spectrometric methods}, year={2014}, pages={2343-2353}, language={eng}, issn={1539-7262}, volume={55}, number={11}, note={Gesehen am: 05.05.2015}, journal={Journal of lipid research}, doi={10.1194/jlr.M051821}, } @article{UBHD-67813513, author={Marsching, Christian and Porubský, Štefan and Bolenz, Christian and Hopf, Carsten}, title={Renal sulfatides}, subtitle={sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction}, year={2014}, pages={2354-2369}, language={eng}, issn={1539-7262}, volume={55}, number={11}, note={Gesehen am: 05.05.2015}, journal={Journal of lipid research}, doi={10.1194/jlr.M051839}, } @article{UBHD-67957392, author={Munteanu, Bogdan and Burgermeister, Elke and Ebert, Matthias and Hopf, Carsten}, title={Label-free in situ monitoring of histone deacetylase drug target engagement by matrix-assisted laser desorption ionization-mass spectrometry biotyping and imaging}, year={2014}, pages={4642-4647}, language={eng}, issn={1520-6882}, volume={86}, number={10}, note={Gesehen am: 16.03.2016}, journal={Analytical chemistry}, doi={10.1021/ac500038j}, } @article{UBHD-68299936, author={Munteanu, Bogdan and Reitzenstein, Carolina von and H{\"a}nsch, Gertrud Maria and Meyer, Bj{\"o}rn and Hopf, Carsten}, title={Sensitive, robust and automated protein analysis of cell differentiation and of primary human blood cells by intact cell MALDI mass spectrometry biotyping}, year={2012}, pages={2277-2286}, language={eng}, issn={1618-2650}, volume={404}, number={8}, note={Gesehen am 29.08.2018}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-012-6357-0}, } @article{UBHD-67375781, author={Munteanu, Bogdan and Reitzenstein, Carolina von and H{\"a}nsch, Gertrud Maria and Meyer, Bj{\"o}rn and Hopf, Carsten}, title={Sensitive, robust and automated protein analysis of cell differentiation and of primary human blood cells by intact cell MALDI mass spectrometry biotyping}, year={2012}, pages={2277-2286}, language={eng}, issn={1618-2642}, volume={404}, number={8}, journal={Analytical & bioanalytical chemistry}, } @article{UBHD-68571360, author={Rabe, Jan-Hinrich and Hohenberger, Peter and Marx, Alexander and Platten, Michael and Opitz, Christiane and Hopf, Carsten}, title={Fourier transform infrared microscopy enables guidance of automated mass spectrometry imaging to predefined tissue morphologies}, year={2018}, pages={11 S.}, language={eng}, issn={2045-2322}, volume={8(2018) Artikel-Nummer 313}, number={11 Seiten}, note={Gesehen am 28.04.2020}, journal={Scientific reports}, doi={10.1038/s41598-017-18477-6}, } @article{UBHD-68251873, author={Ruh, Hermelindis and Hopf, Carsten}, title={Identification of serum proteins bound to industrial nanomaterials}, year={2012}, pages={41-50}, language={eng}, issn={1879-3169}, volume={208}, number={1}, note={Available online 3 October 2011 ; Gesehen am 14.05.2018}, journal={Toxicology letters}, doi={10.1016/j.toxlet.2011.09.009}, } @article{UBHD-67544491, author={Ruh, Hermelindis and Sticht, Carsten and Gretz, Norbert and Hopf, Carsten}, title={MALDI imaging MS reveals candidate lipid markers of polycystic kidney disease}, year={2013}, pages={2785-2794}, language={eng}, issn={1873-2194}, volume={54}, number={10}, note={Gesehen am: 27.02.2014}, journal={Progress in lipid research}, doi={10.1194/jlr.M040014}, } @article{UBHD-67506695, author={Ruh, Hermelindis and Gretz, Norbert and Hopf, Carsten}, title={Quantitative characterization of tissue globotetraosylceramides in a rat model of polycystic kidney disease by primadrop sample preparation and indirect high-performance thin layer chromatography-matrix-assisted laser desorption/ionization-time-of-flight-mass spectrometry with automated data acquisition}, year={2013}, pages={6233-6240}, language={eng}, issn={1520-6882}, volume={85}, number={13}, note={Gesehen am: 04.12.2013}, journal={Analytical chemistry}, doi={10.1021/ac400931u}, } @article{UBHD-69343421, author={Schmidt, Stefan Michael Walter and Geisel, Alexander and Enzlein, Thomas and Fr{\"o}hlich, Bj{\"o}rn C. and Pritchett, Louise and Verneret, Melanie and Graf, Christian and Hopf, Carsten}, title={Label-free assessment of complement-dependent cytotoxicity of therapeutic antibodies via a whole-cell MALDI mass spectrometry bioassay}, year={2024}, pages={21462-1-21462-11}, language={eng}, issn={2045-2322}, volume={14}, number={Artikel-ID 21462}, note={Gesehen am 09.05.2025}, journal={Scientific reports}, doi={10.1038/s41598-024-71483-3}, } @article{UBHD-67598797, author={Schulz, Sandra and Hopf, Carsten}, title={DMSO-enhanced MALDI MS imaging with normalization against a deuterated standard for relative quantification of dasatinib in serial mouse pharmacology studies}, year={2013}, pages={9467-9476}, language={eng}, issn={1618-2650}, volume={405}, number={29}, note={Gesehen am: 18.06.2014}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-013-7393-0}, } @article{UBHD-67554970, author={Schwamb, Sebastian and Hopf, Carsten and Hafner, Mathias}, title={Monitoring CHO cell cultures}, subtitle={cell stress and early apoptosis assessment by mass spectrometry}, year={2013}, pages={452-461}, language={eng}, issn={1873-4863}, volume={168}, number={4}, note={Gesehen am: 20.03.2014}, journal={Journal of biotechnology}, doi={10.1016/j.jbiotec.2013.10.014}, } @article{UBHD-68202331, author={Schwartz, Matthias and Hopf, Carsten}, title={Standardized processing of MALDI imaging raw data for enhancement of weak analyte signals in mouse models of gastric cancer and Alzheimer’s disease}, year={2015}, pages={2255-2264}, language={eng}, issn={1618-2650}, volume={407}, number={8}, note={Gesehen am 15.12.2017}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-014-8356-9}, } @article{UBHD-68287037, author={Seyrantepe, Volkan and Marsching, Christian and Erich, Katrin and Hopf, Carsten}, title={Murine sialidase neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease}, year={2018}, pages={26-41}, language={eng}, issn={1090-2430}, volume={299}, note={Published online: 30 September 2017 ; Gesehen am 19.07.2018}, journal={Experimental neurology}, doi={10.1016/j.expneurol.2017.09.012}, } @article{UBHD-68230505, author={Siebenhaar, Markus and Hopf, Carsten}, title={Personalized monitoring of therapeutic salicylic acid in dried blood spots using a three-layer setup and desorption electrospray ionization mass spectrometry}, year={2015}, pages={7229-7238}, language={eng}, issn={1618-2650}, volume={407}, number={23}, note={Gesehen am 14.03.2018}, journal={Analytical and bioanalytical chemistry}, doi={10.1007/s00216-015-8887-8}, } @article{UBHD-67772415, author={Stettner, Paula and Hopf, Carsten}, title={Sulfatides are required for renal adaptation to chronic metabolic acidosis}, year={2013}, pages={9998-10003}, language={eng}, issn={1091-6490}, volume={110}, number={24}, note={Gesehen am: 12.02.2015}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.1217775110}, } @article{UBHD-68404020, author={Weigt, David and Abu Sammour, Denis and Ulrich, Timon and Munteanu, Bogdan and Hopf, Carsten}, title={Automated analysis of lipid drug-response markers by combined fast and high-resolution whole cell MALDI mass spectrometry biotyping}, year={2018}, pages={9 S.}, language={eng}, issn={2045-2322}, volume={8(2018) Artikel-Nummer 11260}, number={9 Seiten}, note={Gesehen am 03.07.2019}, journal={Scientific reports}, doi={10.1038/s41598-018-29677-z}, } @article{UBHD-68433012, author={Weigt, David and Hopf, Carsten and Médard, Guillaume}, title={Studying epigenetic complexes and their inhibitors with the proteomics toolbox}, year={2016}, language={eng}, issn={1868-7083}, volume={8(2016) Artikel-Nummer 76}, number={16 Seiten}, note={Gesehen am 25.09.2019}, journal={Clinical epigenetics}, doi={10.1186/s13148-016-0244-z}, } @article{UBHD-69316568, author={Zoltowska, Katarzyna Marta and Das, Utpal and Lismont, Sam and Enzlein, Thomas and Maesako, Masato and Houser, Mei CQ and Franco, Maria Luisa and {\"O}zcan, Burcu and Gomes Moreira, Diana and Karachentsev, Dmitry and Becker, Ann and Hopf, Carsten and Vilar, Marçal and Berezovska, Oksana and Mobley, William and Chávez-Gutiérrez, Lucía}, title={Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling}, year={2024}, pages={1-34}, language={eng}, issn={2050-084X}, volume={12}, number={Artikel-ID RP90690}, note={Gesehen am 24.02.2024}, journal={eLife}, doi={10.7554/eLife.90690}, }