@article{UBHD-68620249, author={Alsara, Mohammad and L{\"o}ffler, Harald and Fechter, Anne and Bartek, Jiri and Kr{\"a}mer, Alwin}, title={Cep63 recruits Cdk1 to the centrosome}, subtitle={letter}, year={2015}, pages={777-778}, language={eng}, issn={1538-7445}, volume={75}, number={4}, note={Gesehen am 23.07.2020}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-14-3431}, } @article{UBHD-68319534, author={Bochtler, Tilmann and L{\"o}ffler, Harald and Kr{\"a}mer, Alwin}, title={Diagnosis and management of metastatic neoplasms with unknown primary}, year={2018}, pages={199-206}, language={eng}, issn={1930-1111}, volume={35}, number={3}, note={Gesehen am 22.10.2018 ; Available online 26 November 2017}, journal={Seminars in diagnostic pathology}, doi={10.1053/j.semdp.2017.11.013}, } @article{UBHD-68679921, author={Bochtler, Tilmann and Reiling, Anna and Endris, Volker and Hielscher, Thomas and Volckmar, Anna-Lena and Neumann, Olaf and Kirchner, Martina and Budczies, Jan and Heukamp, Lukas C. and Leichsenring, Jonas and Allg{\"a}uer, Michael and Kazdal, Daniel and L{\"o}ffler, Harald and Weichert, Wilko and Schirmacher, Peter and Stenzinger, Albrecht and Kr{\"a}mer, Alwin}, title={Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary}, year={2020}, pages={3053-3064}, language={eng}, issn={1097-0215}, volume={146}, number={11}, note={Gesehen am 14.01.2021}, journal={International journal of cancer}, doi={10.1002/ijc.32882}, } @book{UBHD-67905205, editor={Kr{\"a}mer, Alwin and L{\"o}ffler, Harald}, title={Cancer of unknown primary}, publisher={Springer}, address={Cham}, year={2016}, pages={VI, 194 Seiten}, language={eng}, isbn={978-3-319-22580-7}, library={UB [Signatur: UBN/XH 2000 K89]}, } @book{UBHD-67957356, editor={Kr{\"a}mer, Alwin and L{\"o}ffler, Harald}, title={Cancer of unknown primary}, publisher={Springer}, address={Cham}, year={2016}, pages={Online-Ressource (VI, 194 p. 33 illus., 30 illus. in color, online resource)}, language={eng}, isbn={978-3-319-22581-4}, series={SpringerLink : B{\"u}cher}, note={Includes bibliographical references at the end of each chapters}, doi={10.1007/978-3-319-22581-4}, } @article{UBHD-69064194, author={Heilig, Christoph E. and L{\"o}ffler, Harald and Mahlknecht, Ulrich Rudolph and Janssen, Johannes W. G. and Ho, Anthony Dick and Jauch, Anna and Kr{\"a}mer, Alwin}, title={Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group}, year={2010}, pages={895-902}, language={eng}, issn={1582-4934}, volume={14}, number={4 vom: Apr.}, note={First published: 10 May 2010 ; Gesehen am 11.04.2023}, journal={Journal of cellular and molecular medicine}, doi={10.1111/j.1582-4934.2009.00905.x}, } @article{UBHD-68575790, author={Hemminki, Kari and Chen, Bowang and Kumar, Abhishek and Melander, Olle and Manjer, Jonas and Hallmans, G{\"o}ran and Pettersson-Kymmer, Ulrika and Ohlsson, Claes and Folprecht, Gunnar and L{\"o}ffler, Harald and Kr{\"a}mer, Alwin and F{\"o}rsti, Asta}, title={Germline genetics of cancer of unknown primary (CUP) and its specific subtypes}, year={2016}, pages={22140-22149}, language={eng}, issn={1949-2553}, volume={7}, number={16}, note={Gesehen am 12.05.2020}, journal={OncoTarget}, doi={10.18632/oncotarget.7903}, } @article{UBHD-68264860, author={Karakaya, Kadin and Herbst, Friederike and Ball, Claudia R. and Glimm, Hanno and Kr{\"a}mer, Alwin and L{\"o}ffler, Harald}, title={Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase}, year={2012}, pages={3492-3503}, language={eng}, issn={1551-4005}, volume={11}, number={18}, note={Im Titel ist 0/1 tiefgestellt ; Published online: 16 Aug 2012 ; Gesehen am 25.06.2018}, journal={Cell cycle}, doi={10.4161/cc.21801}, } @article{UBHD-68920072, author={Kr{\"a}mer, Alwin and L{\"o}ffler, Harald and Bergmann, J{\"o}rg Stefan and Hochhaus, Andreas and Hehlmann, R{\"u}diger}, title={Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia}, year={2001}, pages={62-68}, language={eng}, issn={1476-5551}, volume={15}, number={1}, note={Gesehen am 18.05.2022}, journal={Leukemia}, doi={10.1038/sj.leu.2402005}, } @article{UBHD-68447565, author={Kriegsmann, Katharina and L{\"o}ffler, Harald and Eckstein, Volker and Schulz, Renate and Kr{\"a}ker, Sandra and Braun, Ute and Luft, Thomas and Hegenbart, Ute and Sch{\"o}nland, Stefan and Dreger, Peter and Kr{\"a}mer, Alwin and Ho, Anthony Dick and M{\"u}ller-Tidow, Carsten and Hundemer, Michael}, title={CD7 is expressed on a subset of normal CD34-positive myeloid precursors}, year={2018}, pages={318-325}, language={eng}, issn={1600-0609}, volume={101}, number={3}, note={Gesehen am 29.10.2019}, journal={European journal of haematology}, doi={10.1111/ejh.13100}, } @article{UBHD-68965770, author={L{\"o}ffler, Harald and Fechter, Anne and Matuszewska, Marc and Saffrich, Rainer and Mistrik, Martin and Marhold, Joachim and Hornung, Christin and Westermann, Frank and Bartek, Jiri and Kr{\"a}mer, Alwin}, title={Cep63 recruits Cdk1 to the centrosome}, subtitle={implications for regulation of mitotic entry, centrosome amplification, and genome maintenance}, year={2011}, pages={2129-2139}, language={eng}, issn={1538-7445}, volume={71}, number={6}, note={Gesehen am 20.09.2022}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-10-2684}, } @article{UBHD-67821444, author={L{\"o}ffler, Harald and Neben, Kai and Kr{\"a}mer, Alwin}, title={CUP-Syndrom}, subtitle={Epidemiologie und Pathogenese}, year={2014}, pages={107-111}, language={ger}, issn={1432-2102}, volume={54}, number={2}, note={Gesehen am 22.05.2015}, journal={Der Radiologe}, doi={10.1007/s00117-013-2544-z}, } @article{UBHD-68315881, author={L{\"o}ffler, Harald and Fechter, Anne and Liu, Fang and Kr{\"a}mer, Alwin}, title={DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites}, year={2013}, pages={2963-2972}, language={eng}, issn={1476-5594}, volume={32}, number={24}, note={Gesehen am 16.10.2018}, journal={Oncogene}, doi={10.1038/onc.2012.310}, } @article{UBHD-68791956, author={L{\"o}ffler, Harald and Bochtler, Tilmann and Tews, Britta and Tews, Bj{\"o}rn and Ho, Anthony Dick and Lukas, Jiri and Bartek, Jiri and Kr{\"a}mer, Alwin}, title={DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function}, year={2007}, pages={2541-2548}, language={eng}, issn={1551-4005}, volume={6}, number={20}, note={Gesehen am 20.10.2021}, journal={Cell cycle}, doi={10.4161/cc.6.20.4810}, } @book{UBHD-9916200, author={L{\"o}ffler, Harald}, title={Freisetzung und Charakterisierung einer spezifisch mit DNA interagierenden Phosphatase}, year={1999}, pages={92 S.}, language={ger}, school={Heidelberg, Univ., Diss., 1999}, library={UB [Signatur: 99 U 390]}, } @book{UBHD-67820935, author={L{\"o}ffler, Harald}, title={Mechanismen und Konsequenzen chromosomaler Instabilit{\"a}t in malignen Zellen}, year={2013}, pages={Getr. Z{\"a}hlung}, language={ger}, note={Enth. Sonderabdr. - Beitr. engl}, school={Heidelberg, Univ., Habil.-Schr., 2013}, library={UB [Signatur: 2015 U 454]}, } @article{UBHD-68347165, author={L{\"o}ffler, Harald and Pfarr, Nicole and Kriegsmann, Mark and Endris, Volker and Stenzinger, Albrecht and Weichert, Wilko and Kr{\"a}mer, Alwin}, title={Molecular driver alterations and their clinical relevance in cancer of unknown primary site}, year={2016}, pages={44322-44329}, language={eng}, issn={1949-2553}, volume={7}, number={28}, note={Gesehen am 14.01.2019}, journal={OncoTarget}, doi={10.18632/oncotarget.10035}, } @article{UBHD-67963640, author={L{\"o}ffler, Harald and Puthenparambil, Joe and Neben, Kai and Kr{\"a}mer, Alwin}, title={Patients with cancer of unknown primary}, subtitle={a retrospective analysis of 223 patients with adeno carcinoma or undifferentiated carcinoma}, year={2014}, pages={481-487}, language={eng}, issn={1866-0452}, volume={111}, number={27-28}, note={Gesehen am 05.04.2016}, journal={Deutsches {\"A}rzteblatt international}, doi={10.3238/arztebl.2014.0481}, } @article{UBHD-68238481, author={L{\"o}ffler, Harald and Kr{\"a}mer, Alwin}, title={Prognostisch g{\"u}nstige Subgruppen bei Krebs mit unklarem Primarius}, year={2017}, pages={993-999}, language={ger}, issn={1433-0415}, volume={23}, number={12}, note={Gesehen am 03.04.2018}, journal={Der Onkologe}, doi={10.1007/s00761-017-0241-7}, } @article{UBHD-68920061, author={L{\"o}ffler, Harald and Bergmann, J{\"o}rg Stefan and Hochhaus, Andreas and Hehlmann, R{\"u}diger and Kr{\"a}mer, Alwin}, title={Reduced risk for chronic myelogenous leukemia in individuals with the cytochrome P-450 gene polymorphism CYP1A1*2A}, year={2001}, pages={3874-3875}, language={eng}, issn={1528-0020}, volume={98}, number={13}, note={Gesehen am 18.05.2022}, journal={Blood}, doi={10.1182/blood.V98.13.3874}, } @article{UBHD-67820995, author={L{\"o}ffler, Harald and Neben, Kai and Kr{\"a}mer, Alwin}, title={Strukturierte Diagnostik und internistische Therapie des CUP-Syndroms}, year={2014}, pages={112-116}, language={ger}, issn={1432-2102}, volume={54}, number={2}, note={Gesehen am 21.05.2015}, journal={Der Radiologe}, doi={10.1007/s00117-013-2545-y}, } @article{UBHD-68169336, author={Menon, Roopika and Bochtler, Tilmann and L{\"o}ffler, Harald and Kr{\"a}mer, Alwin}, title={Identification of therapeutically targetable genomic alterations in a cohort of patients with CUP using a hybrid-capture based next generation sequencing assay}, year={2016}, pages={S55-S55}, language={eng}, issn={1879-0852}, volume={69}, number={69(2016) Supplement 1}, note={Gesehen am 26.09.2017}, journal={European journal of cancer}, doi={10.1016/S0959-8049(16)32751-4}, } @article{UBHD-68492136, author={Paredes, Roberto and L{\"o}ffler, Harald}, title={EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association}, year={2018}, pages={7662-7674}, language={eng}, issn={1362-4962}, volume={46}, number={15}, note={Gesehen am 21.02.2020}, journal={Nucleic acids research}, doi={10.1093/nar/gky536}, }