@article{UBHD-68805543, author={Behrouz, Somayeh and K{\"u}hl, Nikos and Klein, Christian D.}, title={A facile approach towards amidinophenylalanine derivatives as building blocks for the synthesis of non-natural peptides and peptidomimetics}, year={2021}, pages={1-7}, language={eng}, issn={1873-3581}, volume={81}, number={Artikel-ID 153342}, note={Gesehen am 26.11.2021}, journal={Tetrahedron letters}, doi={10.1016/j.tetlet.2021.153342}, } @article{UBHD-69078957, author={Behrouz, Somayeh and K{\"u}hl, Nikos and Klein, Christian D.}, title={N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors}, year={2023}, pages={1-14}, language={eng}, issn={1768-3254}, volume={251(2023) vom: M{\"a}rz}, number={Artikel-ID 115227}, note={Online verf{\"u}gbar 1. M{\"a}rz 2023, Artikelversion 7. M{\"a}rz 2023 ; Gesehen am 24.05.2023}, journal={European journal of medicinal chemistry}, doi={10.1016/j.ejmech.2023.115227}, } @article{UBHD-68802738, author={Dražić, Tonko and K{\"u}hl, Nikos and Gottscheber, Nicole and Hacker, Christina N. and Klein, Christian D.}, title={The spectrum between substrates and inhibitors}, subtitle={Pinpointing the binding mode of dengue protease ligands with modulated basicity and hydrophobicity}, year={2021}, pages={1-16}, language={eng}, issn={1464-3391}, volume={48}, number={Artikel-ID 116412}, note={Gesehen am 17.11.2021}, journal={Bioorganic & medicinal chemistry}, doi={10.1016/j.bmc.2021.116412}, } @article{UBHD-68749325, author={K{\"u}hl, Nikos and Leuthold, Mila and Behnam, Mira A. M. and Klein, Christian D.}, title={Beyond basicity}, subtitle={discovery of nonbasic DENV-2 protease inhibitors with potent activity in cell culture}, year={2021}, pages={4567-4587}, language={eng}, issn={1520-4804}, volume={64}, number={8}, note={Gesehen am 16.06.2021}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.0c02042}, } @article{UBHD-68983009, author={K{\"u}hl, Nikos and Lang, Johannes and Leuthold, Mila and Klein, Christian D.}, title={Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases}, year={2022}, pages={1-14}, language={eng}, issn={1768-3254}, volume={240}, number={Artikel-ID 114585}, note={Gesehen am 08.11.2022}, journal={European journal of medicinal chemistry}, doi={10.1016/j.ejmech.2022.114585}, } @book{UBHD-68744471, author={K{\"u}hl, Nikos}, organization={Universit{\"a}t Heidelberg}, title={Entwicklung und Optimierung von Hemmstoffen flaviviraler Proteasen mit antiviraler Wirksamkeit}, address={Heidelberg}, year={2021}, pages={248 Seiten}, language={ger}, school={Dissertation, Ruprecht-Karls-Universit{\"a}t Heidelberg, 2021}, library={UB [Signatur: 2021 U 382]}, } @article{UBHD-68640015, author={K{\"u}hl, Nikos and Graf, Dominik Korbinian and Bock, Josephine and Behnam, Mira A. M. and Leuthold, Mila and Klein, Christian D.}, title={A new class of Dengue and west Nile virus protease inhibitors with submicromolar activity in reporter gene DENV-2 protease and viral replication assays}, year={2020}, pages={8179-8197}, language={eng}, issn={1520-4804}, volume={63}, number={15}, note={Gesehen am 24.09.2020}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.0c00413}, } @article{UBHD-69338243, author={Lang, Johannes and Dutta, Sudip Kumar and Leuthold, Mila and Reichert, Lisa and K{\"u}hl, Nikos and Martina, Byron and Klein, Christian D.}, title={Antiviral drug discovery with an optimized biochemical dengue protease assay}, subtitle={Improved predictive power for antiviral efficacy}, year={2025}, pages={1-12}, language={eng}, issn={1872-9096}, volume={234(2025) vom: Feb.}, number={Artikel-ID 106053}, note={Gesehen am 23.04.2025}, journal={Antiviral research}, doi={10.1016/j.antiviral.2024.106053}, } @article{UBHD-68999829, author={Pander, Giulia and Uhl, Philipp and K{\"u}hl, Nikos and Haberkorn, Uwe and Anderl, Jan and Mier, Walter}, title={Antibody-drug conjugates}, subtitle={what drives their progress?}, year={2022}, pages={1-10}, language={eng}, issn={1878-5832}, volume={27}, note={Gesehen am 20.12.2022}, journal={Drug discovery today}, doi={10.1016/j.drudis.2022.06.011}, }