@article{UBHD-68849231, author={Bohaumilitzky, Lena and Kluck, Klaus and H{\"u}neburg, Robert and Gallon, Richard and Nattermann, Jacob and Kirchner, Martina and Kristiansen, Glen and Hommerding, Oliver and Pfuderer, Pauline Luise and Wagner, Lelia and Echterdiek, Fabian Friedrich and K{\"o}segi, Svenja and M{\"u}ller, Nico and Fischer, Konstantin and Nelius, Nina and Hartog, Ben and Borthwick, Gillian and Busch, Elena and Haag, Georg Martin and Bl{\"a}ker, Hendrik and M{\"o}slein, Gabriela and Knebel Doeberitz, Magnus von and Sepp{\"a}l{\"a}, Toni T. and Ahtiainen, Maarit and Mecklin, Jukka-Pekka and Bishop, D Timothy and Burn, John and Stenzinger, Albrecht and Budczies, Jan and Kloor, Matthias and Ahadova, Aysel}, title={The different immune profiles of normal colonic mucosa in cancer-free Lynch syndrome carriers and Lynch syndrome colorectal cancer patients}, year={2022}, pages={907-919.e10}, language={eng}, issn={1528-0012}, volume={162}, number={3 vom: M{\"a}rz}, note={Available online 2 December 2021 ; Gesehen am 24.02.2022}, journal={Gastroenterology}, doi={10.1053/j.gastro.2021.11.029}, } @article{UBHD-69072590, author={Budczies, Jan and Kirchner, Martina and Kluck, Klaus and Kazdal, Daniel and Glade, Julia and Allg{\"a}uer, Michael and Kriegsmann, Mark and Heußel, Claus Peter and Herth, Felix and Winter, Hauke and Meister, Michael and Muley, Thomas and Goldmann, Torsten and Fr{\"o}hling, Stefan and Wermke, Martin and Waller, Cornelius and Tufman, Amanda L. H. and Reck, Martin and Peters, Solange and Schirmacher, Peter and Thomas, Michael and Christopoulos, Petros and Stenzinger, Albrecht}, title={Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma}, year={2022}, pages={251-265}, language={eng}, issn={1432-0851}, volume={71}, number={2}, note={Gesehen am 05.05.2023}, journal={Cancer immunology immunotherapy}, doi={10.1007/s00262-021-02981-w}, url={https://doi.org/10.1007/s00262-021-02981-w}, library={UB}, } @article{UBHD-68706901, author={Budczies, Jan and Kirchner, Martina and Kluck, Klaus and Kazdal, Daniel and Glade, Julia and Allg{\"a}uer, Michael and Kriegsmann, Mark and Heußel, Claus Peter and Herth, Felix and Winter, Hauke and Meister, Michael and Muley, Thomas and Fr{\"o}hling, Stefan and Peters, Solange and Seliger, Barbara and Schirmacher, Peter and Thomas, Michael and Christopoulos, Petros and Stenzinger, Albrecht}, title={A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma}, year={2021}, pages={1-14}, language={eng}, issn={2162-402X}, volume={10}, number={Artikel-ID 1860586}, note={Gesehen am 04.03.2021}, journal={OncoImmunology}, doi={10.1080/2162402x.2020.1860586}, } @article{UBHD-69262473, author={Budczies, Jan and Kazdal, Daniel and Menzel, Michael and Beck, Susanne and Kluck, Klaus and Altb{\"u}rger, Christian and Schwab, Constantin and Allg{\"a}uer, Michael and Ahadova, Aysel and Kloor, Matthias and Schirmacher, Peter and Peters, Solange and Kr{\"a}mer, Alwin and Christopoulos, Petros and Stenzinger, Albrecht}, title={Tumour mutational burden}, subtitle={clinical utility, challenges and emerging improvements}, year={2024}, pages={725-742}, language={eng}, issn={1759-4782}, volume={21}, number={10 vom: Okt.}, note={Zuerst ver{\"o}ffentlicht: 27. August 2024 ; Gesehen am 15.10.2024}, journal={Nature reviews}, doi={10.1038/s41571-024-00932-9}, } @article{UBHD-68958037, author={Christopoulos, Petros and Kluck, Klaus and Kirchner, Martina and L{\"u}ders, Heike and Roeper, Julia and Falkenstern-Ge, Roger-Fei and Szewczyk, Marlen and Sticht, Florian and Saalfeld, Felix C. and Wesseler, Claas and Hackanson, Bj{\"o}rn and Dintner, Sebastian and Faehling, Martin and Kuon, Jonas and Janning, Melanie and Kauffmann-Guerrero, Diego and Kazdal, Daniel and Kurz, Sylke and Eichhorn, Florian and Bozorgmehr, Farastuk and Shah, Rajiv and Tufman, Amanda and Wermke, Martin and Loges, Sonja and Brueckl, Wolfgang M. and Schulz, Christian and Misch, Daniel and Frost, Nikolaj and Kollmeier, Jens and Reck, Martin and Griesinger, Frank and Grohé, Christian and Hong, Jin-Liern and Lin, Huamao M. and Budczies, Jan and Stenzinger, Albrecht and Thomas, Michael}, title={The impact of TP53 co-mutations and immunologic microenvironment on outcome of lung cancer with EGFR exon 20 insertions}, year={2022}, pages={106-118}, language={eng}, issn={1879-0852}, volume={170(2022) vom: Juli}, note={Gesehen am 29.08.2022}, journal={European journal of cancer}, doi={10.1016/j.ejca.2022.04.020}, } @article{UBHD-69112611, author={Goldschmid, Hannah and Kluck, Klaus and Ball, Markus and Kirchner, Martina and Allg{\"a}uer, Michael and Winter, Hauke and Herth, Felix and Heußel, Claus Peter and Pullamsetti, Soni Savai and Savai, Rajkumar and Yong, Timothy Tay Kwang and Schirmacher, Peter and Peters, Solange and Thomas, Michael and Christopoulos, Petros and Budczies, Jan and Stenzinger, Albrecht and Kazdal, Daniel}, title={Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naïve lung adenocarcinomas}, year={2023}, pages={1-9}, language={eng}, issn={1872-8332}, volume={180(2023) vom: Juni}, number={Artikel-ID 107212}, note={Online verf{\"u}gbar: 23. April 2023, Artikelversion: 2. Mai 2023 ; Gesehen am 15.08.2023}, journal={Lung cancer}, doi={10.1016/j.lungcan.2023.107212}, } @article{UBHD-68872046, author={Kirchner, Martina and Kluck, Klaus and Brandt, Regine and Volckmar, Anna-Lena and Penzel, Roland and Kazdal, Daniel and Endris, Volker and Neumann, Olaf and Şeker-Cin, Huriye and Goldschmid, Hannah and Glade, Julia and Allg{\"a}uer, Michael and Kriegsmann, Mark and Winter, Hauke and Muley, Thomas and Perner, Sven Roger and Frost, N. and Reck, M. and Fr{\"o}hling, Stefan and Schirmacher, Peter and Thomas, Michael and Budczies, Jan and Christopoulos, Petros and Stenzinger, Albrecht}, title={The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma}, year={2021}, pages={1-12}, language={eng}, issn={2059-7029}, volume={6}, note={Gesehen am 28.01.2022}, journal={ESMO open}, doi={10.1016/j.esmoop.2021.100253}, } @article{UBHD-69106096, author={Menzel, Michael and Endris, Volker and Schwab, Constantin and Kluck, Klaus and Neumann, Olaf and Beck, Susanne and Ball, Markus and Schaaf, Christian P. and Fr{\"o}hling, Stefan and Lichtner, Peter and Schirmacher, Peter and Kazdal, Daniel and Stenzinger, Albrecht and Budczies, Jan}, title={Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD)}, year={2023}, pages={1-10}, language={eng}, issn={1936-5233}, volume={35(2023) vom: Sept.}, number={Artikel-ID 101706}, note={Online verf{\"u}gbar: 14. Juni 2023 ; Gesehen am 03.08.2023}, journal={Translational oncology}, doi={10.1016/j.tranon.2023.101706}, } @article{UBHD-69196458, author={Menzel, Michael and Kirchner, Martina and Kluck, Klaus and Ball, Markus and Beck, Susanne and Allg{\"a}uer, Michael and Assmann, Christin and Schnorbach, Johannes and Volckmar, Anna-Lena and Tay, Timothy Kwang Yong and Goldschmid, Hannah and Tan, Daniel SW and Thomas, Michael and Kazdal, Daniel and Budczies, Jan and Stenzinger, Albrecht and Christopoulos, Petros}, title={Genomic heterogeneity at baseline is associated with T790M resistance mutations in EGFR-mutated lung cancer treated with the first-/second-generation tyrosine kinase inhibitors}, year={2024}, pages={1-10}, language={eng}, issn={2056-4538}, volume={10}, note={Vorab ver{\"o}ffentlicht: 17. Januar 2024 ; Gesehen am 02.04.2024}, journal={The journal of pathology: clinical research}, doi={10.1002/cjp2.354}, } @article{UBHD-69152024, author={Menzel, Michael and Ossowski, Stephan and Kral, Sebastian and Metzger, Patrick and Horak, Peter and Marienfeld, Ralf and B{\"o}rries, Melanie and Wolter, Steffen and Ball, Markus and Neumann, Olaf and Armeanu-Ebinger, Sorin and Schroeder, Christopher and Matysiak, Uta and Goldschmid, Hannah and Schipperges, Vincent and F{\"u}rstberger, Axel and Allg{\"a}uer, Michael and Eberhardt, Timo and Niew{\"o}hner, Jakob and Blaumeiser, Andreas and Pl{\"o}ger, Carolin and Haack, Tobias and Tay, Timothy Kwang Yong and Kelemen, Olga and Pauli, Thomas Dieter and Kirchner, Martina and Kluck, Klaus and Ott, Alexander and Renner, Marcus and Admard, Jakob and Gschwind, Axel and Laßmann, Silke and Kestler, Hans A. and Fend, Falko and Illert, Anna Lena and Werner, Martin and M{\"o}ller, Peter and Seufferlein, Thomas Theodor Werner and Malek, Nisar Peter and Schirmacher, Peter and Fr{\"o}hling, Stefan and Kazdal, Daniel and Budczies, Jan and Stenzinger, Albrecht}, title={Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients}, year={2023}, pages={1-11}, language={eng}, issn={2397-768X}, volume={7}, note={Gesehen am 12.12.2023}, journal={npj precision oncology}, doi={10.1038/s41698-023-00457-x}, } @article{UBHD-69216576, author={Pouyiourou, Maria and Kraft, Bianca and Wohlfromm, Timothy and Stahl, Michael and Kubuschok, Boris and L{\"o}ffler, Harald and Hacker, Ulrich T. and H{\"u}bner, Gerdt and Weiss, Lena and Bitzer, Michael and Ernst, Thomas and Sch{\"u}tt, Philipp and Hielscher, Thomas and Delorme, Stefan and Kirchner, Martina and Kazdal, Daniel and Ball, Markus and Kluck, Klaus and Stenzinger, Albrecht and Bochtler, Tilmann and Kr{\"a}mer, Alwin}, title={Nivolumab and ipilimumab in recurrent or refractory cancer of unknown primary}, subtitle={a phase II trial}, year={2023}, pages={1-21}, language={eng}, issn={2041-1723}, volume={14}, number={Artikel-ID 6761}, note={Gesehen am 17.05.2024}, journal={Nature Communications}, doi={10.1038/s41467-023-42400-5}, } @article{UBHD-68943370, author={Rempel, Eugen and Kluck, Klaus and Beck, Susanne and Ourailidis, Iordanis and Kazdal, Daniel and Neumann, Olaf and Volckmar, Anna-Lena and Kirchner, Martina and Goldschmid, Hannah and Pfarr, N. and Weichert, Wilko and H{\"u}bschmann, Daniel and Fr{\"o}hling, Stefan and Sutter, Christian and Schaaf, Christian P. and Schirmacher, Peter and Endris, Volker and Stenzinger, Albrecht and Budczies, Jan}, title={Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD)}, year={2022}, pages={1-13}, language={eng}, issn={2397-768X}, volume={6}, number={Artikel-ID 36}, note={Gesehen am 18.07.2022}, journal={npj precision oncology}, doi={10.1038/s41698-022-00276-6}, url={https://doi.org/10.1038/s41698-022-00276-6}, library={UB}, } @article{UBHD-69144256, author={Romanovsky, Eva and Kluck, Klaus and Ourailidis, Iordanis and Menzel, Michael and Beck, Susanne and Ball, Markus and Kazdal, Daniel and Christopoulos, Petros and Schirmacher, Peter and Stiewe, Thorsten and Stenzinger, Albrecht and Budczies, Jan}, title={Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis}, year={2023}, pages={1-14}, language={eng}, issn={2058-7716}, volume={9(2023) vom: Apr.}, number={Artikel-ID 126}, note={Gesehen am 20.11.2023}, journal={Cell death discovery}, doi={10.1038/s41420-023-01413-1}, } @article{UBHD-69149505, author={Şeker-Cin, Huriye and Tay, Timothy Kwang Yong and Kazdal, Daniel and Kluck, Klaus and Ball, Markus and Neumann, Olaf and Winter, Hauke and Herth, Felix and Heußel, Claus Peter and Savai, Rajkumar and Schirmacher, Peter and Thomas, Michael and Budczies, Jan and Allg{\"a}uer, Michael and Christopoulos, Petros and Stenzinger, Albrecht and Volckmar, Anna-Lena}, title={Analysis of rare fusions in NSCLC}, subtitle={genomic architecture and clinical implications}, year={2023}, pages={1-14}, language={eng}, issn={1872-8332}, volume={184(2023) vom: Okt.}, number={Artikel-ID 107317}, note={Online verf{\"u}gbar: 27. Juli 2023, Artikelversion: 14. August 2023 ; Gesehen am 05.12.2023}, journal={Lung cancer}, doi={10.1016/j.lungcan.2023.107317}, } @article{UBHD-68697237, author={Sha, Dan and Jin, Zhaohui and Budczies, Jan and Kluck, Klaus and Stenzinger, Albrecht and Sinicrope, Frank A.}, title={Tumor mutational burden as a predictive biomarker in solid tumors}, year={2020}, pages={1808-1825}, language={eng}, issn={2159-8290}, volume={10}, number={12}, note={Gesehen am 09.02.2021}, journal={Cancer discovery}, doi={10.1158/2159-8290.CD-20-0522}, } @article{UBHD-69365385, author={Thunnissen, Erik and Blaauwgeers, Hans and Filipello, Federica and Lissenberg-Witte, Birgit and Minami, Yuko and Noguchi, Masayuki and Quesne, John Le and Papotti, Mauro Giulio and Flieder, Douglas B. and Pelosi, Giuseppe and Sansano, Irene and Berezowska, Sabina and Ryška, Aleš and Brcic, Luka and Motoi, Noriko and Nakatani, Yukio and Kuempers, Christiane and Hofman, Paul and Hofman, Veronique and Dale, Vibeke Grotnes and Rossi, Giulio and Ambrosi, Francesca and Matsubara, Daisuke and Ishikawa, Yuichi and Weynand, Birgit and Calabrese, Fiorella and Pezzuto, Federica and Kern, Izidor and Nicholson, Siobhan and Mutka, Aino and Dacic, Sanja and Beasley, Mary Beth and Arrigoni, Gianluigi and Timens, Wim and Ooft, Marc and Brinkhuis, Mariel and Bulkmans, Nicole and Britstra, Rieneke and Vreuls, Willem and Jones, Kirk D. and von der Th{\"u}sen, Jan H. and Hager, Hendrik and Perner, Sven and Moore, David and Leonte, Diana Gabriela and Al-Janabi, Shaimaa and Schønau, Andreas and Neumann, Olaf and Kluck, Klaus and Ourailidis, Iordanis and Ball, Markus and Budczies, Jan and Kazdal, Daniel and Stenzinger, Albrecht}, title={A reproducibility study on invasion in small pulmonary adenocarcinoma according to the WHO and a modified classification, supported by biomarkers}, year={2025}, pages={1-13}, language={eng}, issn={1872-8332}, volume={199(2025) vom: Jan.}, number={Artikel-ID 108060}, note={Gesehen am 14.07.2025}, journal={Lung cancer}, doi={10.1016/j.lungcan.2024.108060}, }