@book{UBHD-68078286, author={Albrecht, Marco and Stichel, Damian and M{\"u}ller, Benedikt and Sticht, Carsten and Gretz, Norbert and Breuhahn, Kai and Matth{\"a}us, Franziska}, title={TTCA}, subtitle={an R package for the identification of differentially expressed genes in time course microarray data}, publisher={BioMed Central; Springer}, address={London; Berlin; Heidelberg}, year={2017}, pages={1 Online-Ressource (11 Seiten)}, language={eng}, note={Aus: BMC Bioinformatics, 18 (2017), Nr. 33. pp. 1-11. ISSN 1471-2105}, doi={10.1186/s12859-016-1440-8}, url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-224886}, library={UB}, } @article{UBHD-68305730, author={Albrecht, Marco and Stichel, Damian and M{\"u}ller, Benedikt and Sticht, Carsten and Gretz, Norbert and Klingm{\"u}ller, Ursula and Breuhahn, Kai and Matth{\"a}us, Franziska}, title={TTCA}, subtitle={an R package for the identification of differentially expressed genes in time course microarray data}, year={2017}, pages={11 S.}, language={eng}, issn={1471-2105}, volume={18(2017) Artikel-Nummer 33}, number={11 Seiten}, note={Gesehen am 18.09.2018}, journal={BMC bioinformatics}, doi={10.1186/s12859-016-1440-8}, } @article{UBHD-69281528, author={Albrecht, Thomas and Rossberg, Annik and Rose, Fabian and Breuhahn, Kai and Baumann, Eva-Marie and Tóth, Marcell and Brinkmann, Fritz and Charbel, Alphonse and Vogel, Monika Nadja and K{\"o}hler, Bruno Christian and Mehrabi, Arianeb and B{\"u}chler, Markus W. and Singer, Stephan and Solass, Wiebke and Straub, Beate and Schirmacher, Peter and R{\"o}ssler, Stephanie and Goeppert, Benjamin}, title={Combined analysis of albumin in situ hybridisation and C reactive protein immunohistochemistry for the diagnosis of intrahepatic cholangiocarcinoma}, subtitle={towards a molecular classification paradigm}, edition={Early view}, year={2024}, pages={1-10}, language={eng}, issn={1472-4146}, number={early view}, note={Gesehen am 09.12.2024}, journal={Journal of clinical pathology}, doi={10.1136/jcp-2024-209429}, url={https://doi.org/10.1136/jcp-2024-209429}, library={UB}, } @article{UBHD-69356968, author={Assal, Reem Amr and Abd El-bary, Rowan Bahaa El-din and Youness, Rana A. and Abdelrahman, Mohamed Mamdouh and Zahran, Hala and Hosny, Karim Adel and Esmat, Gamal and Breuhahn, Kai and El-Ekiaby, Nada and Fawzy, Injie Omar and Abdelaziz, Ahmed Ihab}, title={OncomiR-181a promotes carcinogenesis by repressing the extracellular matrix proteoglycan decorin in hepatocellular carcinoma}, year={2024}, pages={1-14}, language={eng}, issn={1471-230X}, volume={24}, number={Artikel-ID 337}, note={Gesehen am 17.06.2025}, journal={BMC gastroenterology}, doi={10.1186/s12876-024-03413-6}, } @article{UBHD-68260782, author={Beuke, Katharina and Pinna, Federico and Liebe, Roman and Bissinger, Michaela and Schirmacher, Peter and Dooley, Steven and Kummer, Ursula and Breuhahn, Kai and Sahle, Sven}, title={Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction}, year={2017}, pages={796-813}, language={eng}, issn={1742-4658}, volume={284}, number={5}, note={Gesehen am 13.06.2018}, journal={The FEBS journal}, doi={10.1111/febs.14022}, } @article{UBHD-69046243, author={Breuhahn, Kai and Schirmacher, Peter}, title={A cellular view of Nf2 in liver homeostasis and tumorigenesis}, year={2010}, pages={363-364}, language={eng}, issn={1878-1551}, volume={19}, number={3}, note={Gesehen am 01.03.2023}, journal={Developmental cell}, doi={10.1016/j.devcel.2010.08.015}, } @article{UBHD-69046212, author={Breuhahn, Kai}, title={Molekulare Progressionsmechanismen der humanen Hepatokarzinogenese}, year={2010}, pages={170-176}, language={ger and eng}, issn={1432-1963}, volume={31}, number={2}, note={Gesehen am 01.03.2023}, journal={Der Pathologe}, doi={10.1007/s00292-010-1337-7}, } @book{UBHD-66840277, author={Breuhahn, Kai}, title={Molekulare Progressionsmechanismen der humanen Hepatokarzinogenese}, year={2009}, pages={Getr. Z{\"a}hl.}, language={ger}, note={Enth{\"a}lt Zeitschriftenaufs{\"a}tze}, school={Heidelberg, Univ., Habil.-Schr., 2009}, library={UB [Signatur: 2010 U 66]}, } @article{UBHD-68933477, author={Breuhahn, Kai and Gores, Gregory J. and Schirmacher, Peter}, title={Reply}, year={2011}, pages={738-739}, language={eng}, issn={1527-3350}, volume={54}, number={2}, note={Gesehen am 22.06.2022}, journal={Hepatology}, doi={10.1002/hep.24425}, } @article{UBHD-69046223, author={Breuhahn, Kai and Schirmacher, Peter}, title={Signaling networks in human hepatocarcinogenesis}, subtitle={novel aspects and therapeutic options}, year={2010}, pages={251-277}, language={eng}, issn={1878-0814}, volume={97}, note={Gesehen am 01.03.2023}, journal={Progress in molecular biology and translational science}, doi={10.1016/B978-0-12-385233-5.00009-X.}, } @article{UBHD-67242008, author={Breuhahn, Kai and Gores, Gregory J. and Schirmacher, Peter}, title={Strategies for hepatocellular carcinoma therapy and diagnostics}, subtitle={lessons learned from high throughput and profiling approaches}, year={2011}, pages={2112-2121}, language={eng}, issn={0270-9139}, volume={53}, number={6}, journal={Hepatology}, } @article{UBHD-68138506, author={Delogu, Salvatore and Longerich, Thomas and Waldburger, Nina and Breuhahn, Kai}, title={SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice}, year={2015}, pages={2222-2234}, language={eng}, issn={1949-2553}, volume={6}, number={4}, note={Published online December 10, 2014 ; Gesehen am 14.07.2017}, journal={OncoTarget}, doi={10.18632/oncotarget.2945}, } @article{UBHD-69276353, author={Dropmann, Anne and Alex, Sophie and Schorn, Katharina and Tong, Chenhao and Caccamo, Tiziana and Godoy, Patricio and Ilkavets, Iryna and Liebe, Roman and González Leiva, Daniela Fernanda and Hengstler, Jan G. and Piiper, Albrecht and Quagliata, Luca and Matter, Matthias S. and Waidmann, Oliver and Finkelmeier, Fabian and Feng, Teng and Weiss, Thomas S. and Rahbari, Nuh Nabi and Birgin, Emrullah and Rasbach, Erik and R{\"o}ssler, Stephanie and Breuhahn, Kai and Tóth, Marcell and Ebert, Matthias and Dooley, Steven and Hammad, Seddik and Meindl-Beinker, Nadja M.}, title={The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects}, year={2024}, pages={1-10}, language={eng}, issn={1090-2104}, volume={732}, number={Artikel-ID 150409}, note={Online verf{\"u}gbar: 16. Juli 2024, Artikelversion: 20. Juli 2024 ; Gesehen am 25.11.2024}, journal={Biochemical and biophysical research communications}, doi={10.1016/j.bbrc.2024.150409}, } @article{UBHD-68480911, author={Drucker, Elisabeth and Pusch, Stefan and Herpel, Esther and Goeppert, Benjamin and R{\"o}ssler, Stephanie and Schirmacher, Peter and Breuhahn, Kai}, title={Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer}, year={2019}, pages={14 S.}, language={eng}, issn={1478-811X}, volume={17(2019}, note={Gesehen am 27.01.2020}, journal={Cell communication and signaling}, doi={10.1186/s12964-019-0456-x}, } @article{UBHD-67694290, author={Dzieran, Johanna and Feng, Teng and Breuhahn, Kai and Dooley, Steven and Meindl-Beinker, Nadja M.}, title={Comparative analysis of TGF-beta/smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines}, year={2013}, pages={e72252}, language={eng}, issn={1932-6203}, volume={8}, number={8}, note={Gesehen am: 29.10.2014}, journal={PLOS ONE}, doi={10.1371/journal.pone.0072252}, } @book{UBHD-68615092, organization={Universit{\"a}t Heidelberg / Pathologisches Institut and BioQuant}, title={eBio - Modul II - Verbundprojekt: MS_DILI - Multi-Skalen Modellierung der Medikament-induzierten Lebersch{\"a}digung - Teilprojekt H}, subtitle={Abschlussbericht zum Forschungsvorhaben}, publisher={[Universit{\"a}tsklinik Heidelberg]}, address={Heidelberg}, year={2019}, pages={9 Bl{\"a}tter}, language={ger}, note={F{\"o}rderkennzeichen BMBF 031L0074H ; Verbundnummer 01167549 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, keywords={Arzneimittelforschung / Arzneimittelnebenwirkung / Hepatose / Hepatotoxizit{\"a}t / Signaltransduktion / Paracetamol / Systemmedizin}, } @book{UBHD-68988066, organization={Universit{\"a}t Heidelberg / Pathologisches Institut and BioQuant}, title={eBio - Modul II - Verbundprojekt: MS_DILI - Multi-Skalen Modellierung der Medikament-induzierten Lebersch{\"a}digung - Teilprojekt H}, subtitle={Abschlussbericht zum Forschungsvorhaben}, publisher={Universit{\"a}tsklinik Heidelberg}, address={Heidelberg}, year={2019}, pages={1 Online-Ressource (9 Seiten, 983,84 KB)}, language={ger}, note={F{\"o}rderkennzeichen BMBF 031L0074H ; Verbundnummer 01167549 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, doi={10.2314/KXP:172501579X}, keywords={Arzneimittelforschung / Arzneimittelnebenwirkung / Hepatose / Hepatotoxizit{\"a}t / Signaltransduktion / Paracetamol / Systemmedizin}, } @article{UBHD-68404464, author={Elßner, Christin and Goeppert, Benjamin and Longerich, Thomas and Scherr, Anna-Lena and Rupp, Christian and Kather, Jakob Nikolas and Kautz, Nicole and Breuhahn, Kai and Gdynia, Georg and R{\"o}ssler, Stephanie and Schirmacher, Peter and J{\"a}ger, Dirk and Sch{\"o}lch, Sebastian and K{\"o}hler, Bruno Christian}, title={Nuclear translocation of RELB is increased in diseased human liver and promotes ductular reaction and biliary fibrosis in mice}, year={2019}, pages={30 S.}, language={eng}, issn={1528-0012}, volume={156(2019}, note={Available online 13 November 2018 ; Gesehen am 04.07.2019}, journal={Gastroenterology}, doi={10.1053/j.gastro.2018.11.018}, } @article{UBHD-68402292, author={El Tayebi, Hend M. and Breuhahn, Kai}, title={miR-615-5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma}, year={2012}, pages={3309-3316}, language={eng}, issn={1873-3468}, volume={586}, number={19}, note={Gesehen am 27.06.2019}, journal={FEBS letters}, doi={10.1016/j.febslet.2012.06.054}, } @article{UBHD-68712648, author={Fiegler, Nathalie and Textor, Sonja and Arnold, Annette and R{\"o}lle, Alexander and Oehme, Ina and Breuhahn, Kai and Moldenhauer, Gerhard and Witzens-Harig, Mathias and Cerwenka, Adelheid}, title={Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells}, year={2013}, pages={684-693}, language={eng}, issn={1528-0020}, volume={122}, number={5}, note={Gesehen am 15.03.2021}, journal={Blood}, doi={10.1182/blood-2013-02-482513}, } @article{UBHD-68261873, author={Ganzinger, Matthias and He, Shan and Breuhahn, Kai and Knaup-Gregori, Petra}, title={On the ontology based representation of cell lines}, year={2012}, pages={12 S.}, language={eng}, issn={1932-6203}, volume={7(2012}, note={Gesehen am 15.06.2018}, journal={PLOS ONE}, doi={10.1371/journal.pone.0048584}, } @article{UBHD-67660550, author={Géraud, Cyrill and Weiß, Christel and Damm, Friederike and Schmieder, Astrid and Schirmacher, Peter and Augustin, Hellmut and Goerdt, Sergij and Mogler, Carolin and Evdokimov, Konstantin and Lu, Shun and Schledzewski, Kai and Reiners-Koch, Philipp-Sebastian and Breuhahn, Kai and Longerich, Thomas and Marx, Alexander}, title={Endothelial transdifferentiation in hepatocellular carcinoma}, subtitle={loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival}, year={2013}, pages={1428-1440}, language={eng}, issn={1478-3231}, volume={33}, number={9}, note={Gesehen am: 13.08.2014}, journal={Liver international}, doi={10.1111/liv.12262}, } @article{UBHD-68964255, author={Gerber, Tiemo Sven and Ridder, Dirk Andreas and Schindeldecker, Mario and Weinmann, Arndt and Duret, Diane and Breuhahn, Kai and Galle, Peter R. and Schirmacher, Peter and Roth, Wilfried and Lang, Hauke and Straub, Beate Katharina}, title={Constitutive occurrence of E}, subtitle={N-cadherin heterodimers in adherens junctions of hepatocytes and derived tumors}, year={2022}, pages={1-25}, language={eng}, issn={2073-4409}, volume={11}, note={Gesehen am 14.09.2022}, journal={Cells}, doi={10.3390/cells11162507}, } @article{UBHD-69064740, author={Goeppert, Benjamin and Schmezer, Peter and Dutruel, Céline and Oakes, Christopher C. and Renner, Marcus and Breinig, Marco and Warth, Arne and Vogel, Monika Nadja and Mittelbronn, Michel Guy André and Mehrabi, Arianeb and Gdynia, Georg and Penzel, Roland and Longerich, Thomas and Breuhahn, Kai and Popanda, Odilia and Plass, Christoph and Schirmacher, Peter and Kern, Michael A.}, title={Down-regulation of tumor suppressor a kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms}, year={2010}, pages={2023-2033}, language={eng}, issn={1527-3350}, volume={52}, number={6}, note={Gesehen am 12.04.2023}, journal={Hepatology}, doi={10.1002/hep.23939}, } @article{UBHD-67686327, author={Goeppert, Benjamin and Mehrabi, Arianeb and Hafezi, Mohammadreza and Stenzinger, Albrecht and Warth, Arne and Breuhahn, Kai and Renner, Marcus and Weichert, Wilko and Schirmacher, Peter}, title={Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway}, year={2014}, pages={544-554}, language={eng}, issn={1527-3350}, volume={59}, number={2}, note={Gesehen am 13.10.2014}, journal={Hepatology}, doi={10.1002/hep.26721}, } @article{UBHD-68389248, author={González-Vallinas, Margarita and Rodríguez Paredes, Manuel and Sticht, Carsten and Stichel, Damian and Lorenzo Bermejo, Justo and Torre, Carolina de la and Warth, Arne and Gretz, Norbert and Tschaharganeh, Darjus-Felix and Schirmacher, Peter and Matth{\"a}us, Franziska and Breuhahn, Kai}, title={Epigenetically regulated chromosome 14q32 miRNA cluster induces metastasis and predicts poor prognosis in lung adenocarcinoma patients}, year={2018}, pages={390-402}, language={eng}, issn={1557-3125}, volume={16}, number={3}, note={Gesehen am 13.05.2019}, journal={Molecular cancer research}, doi={10.1158/1541-7786.MCR-17-0334}, } @article{UBHD-68621797, author={González-Vallinas, Margarita and Breuhahn, Kai}, title={MicroRNAs are key regulators of hepatocellular carcinoma (HCC) cell dissemination}, subtitle={what we learned from microRNA-494}, year={2016}, pages={372-376}, language={eng}, issn={2304-389X}, volume={5}, number={4}, note={Gesehen am 29.07.2020}, journal={Hepatobiliary surgery and nutrition}, doi={10.21037/hbsn.2016.05.07}, } @article{UBHD-67903438, author={Gutschner, Tony and H{\"a}mmerle, Monika and Hofmann, Nina and Longerich, Thomas and Breuhahn, Kai and Schirmacher, Peter and Diederichs, Sven}, title={Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hHepatocellular carcinoma}, year={2014}, pages={1900-1911}, language={eng}, issn={1527-3350}, volume={59}, number={5}, note={Gesehen am 17.11.2015}, journal={Hepatology}, doi={10.1002/hep.26997}, } @article{UBHD-68701998, author={H{\"a}mmerle, Monika and Gutschner, Tony and Uckelmann, Hannah Julia and {\"O}zg{\"u}r, Sevim and Fiškin, Evgenij Ilʹič and Groß, Matthias and Skawran, Britta and Geffers, Robert and Longerich, Thomas and Breuhahn, Kai and Schirmacher, Peter and Stoecklin, Georg and Diederichs, Sven}, title={Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)}, year={2013}, pages={1703-1712}, language={eng}, issn={1527-3350}, volume={58}, number={5}, note={Gesehen am 19.10.2021}, journal={Hepatology}, doi={10.1002/hep.26537}, } @article{UBHD-68486667, author={Holzer, Kerstin and Drucker, Elisabeth and Oliver, Scott and Winkler, Juliane and Eiteneuer, Eva and Herpel, Esther and Breuhahn, Kai and Singer, Stephan}, title={Cellular apoptosis susceptibility (CAS) is overexpressed in thyroid carcinoma and maintains tumor cell growth}, subtitle={a potential link to the BRAFV600E mutation}, year={2016}, pages={1679-1687}, language={eng}, issn={1791-2423}, volume={48}, number={4}, note={Gesehen am 07.02.2020 ; Im Titel ist "V600E" in BRAFV600E hochgestellt}, journal={International journal of oncology}, doi={10.3892/ijo.2016.3388}, } @article{UBHD-68410840, author={Holzer, Kerstin and Drucker, Elisabeth and Baßler, Jochen and R{\"o}ssler, Stephanie and Breuhahn, Kai and Hurt, Ed and Schirmacher, Peter and Singer, Stephan}, title={Nucleoporin Nup155 is part of the p53 network in liver cancer}, year={2019}, pages={13 S.}, language={eng}, issn={2041-1723}, volume={10(2019) Artikel-Nummer 2147}, number={13 Seiten}, note={Gesehen am 22.07.2019}, journal={Nature Communications}, doi={10.1038/s41467-019-10133-z}, } @article{UBHD-68299572, author={Holzer, Kerstin and Drucker, Elisabeth and R{\"o}ssler, Stephanie and Waldburger, Nina and Eiteneuer, Eva and Herpel, Esther and Breuhahn, Kai and Schirmacher, Peter and Singer, Stephan}, title={Proteomic analysis reveals GMP synthetase as p53 repression target in liver cancer}, year={2017}, pages={228-235}, language={eng}, issn={1525-2191}, volume={187}, number={2}, note={Available online 7 December 2016 ; Gesehen am 28.08.2018}, journal={The American journal of pathology}, doi={10.1016/j.ajpath.2016.09.022}, } @article{UBHD-67887732, author={Horwitz, Elad and Koschny, Ronald and Ganten, Tom M. and Mogler, Carolin and Heß, Jochen and Breuhahn, Kai and Schirmacher, Peter}, title={Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment}, year={2014}, pages={730-743}, language={eng}, issn={2159-8290}, volume={4}, number={6}, note={Gesehen am 16.10.2015}, journal={Cancer discovery}, doi={10.1158/2159-8290.CD-13-0782}, } @article{UBHD-68476570, author={Jansen, Peter and Breuhahn, Kai and Teufel, Andreas and Dooley, Steven}, title={Editorial}, subtitle={Systems biology and bioinformatics in gastroenterology and hepatology}, year={2019}, language={eng}, issn={1664-042X}, volume={10(2019) Artikel-Nummer 1438}, number={4 Seiten}, note={Gesehen am 15.01.2020}, journal={Frontiers in physiology}, doi={10.3389/fphys.2019.01438}, } @article{UBHD-68576248, author={Kittas, Aristotelis and Delobelle, Aurélien and Schmitt, Sabrina and Breuhahn, Kai and Guziolowski, Carito and Grabe, Niels}, title={Directed random walks and constraint programming reveal active pathways in hepatocyte growth factor signaling}, year={2016}, pages={350-360}, language={eng}, issn={1742-4658}, volume={283}, number={2}, note={Gesehen am 13.05.2020}, journal={The FEBS journal}, doi={10.1111/febs.13580}, } @article{UBHD-68716976, author={Koschny, Ronald and Brost, Sylvia and Hinz, Ulf and Sykora, Jaromir and Batke, Emanuela M. and Singer, Stephan and Breuhahn, Kai and Stremmel, Wolfgang and Walczak, Henning and Schemmer, Peter and Schirmacher, Peter and Ganten, Tom M.}, title={Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma}, year={2013}, pages={1-11}, language={eng}, issn={1471-2407}, volume={13}, number={Artikel-ID 532}, note={Gesehen am 04.11.2021}, journal={BMC cancer}, doi={10.1186/1471-2407-13-532}, } @article{UBHD-69054725, author={Kossatz-B{\"o}hlert, Uta and Breuhahn, Kai and Wolf, Benita and Hardtke-Wolenski, Matthias and Wilkens, Ludwig and Steinemann, Doris and Singer, Stephan and Brass, Felicitas and Kubicka, Stefan and Schlegelberger, Brigitte and Schirmacher, Peter and Manns, Michael P. and Singer, Jeffrey D. and Malek, Nisar P.}, title={The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells}, year={2010}, pages={3820-3833}, language={eng}, issn={1558-8238}, volume={120}, number={11 vom: Nov.}, note={Gesehen am 22.03.2023}, journal={The journal of clinical investigation}, doi={10.1172/JCI41959}, } @article{UBHD-69276319, author={Krieg, Stephan and Rohde, Thomas and Rausch, Tobias and Butthof, Luise and Wendler-Link, Lena and Eckert, Christoph and Breuhahn, Kai and Galy, Bruno and Korbel, Jan Oliver and Billmann, Maximilian and Breinig, Marco and Tschaharganeh, Darjus-Felix}, title={Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers}, year={2024}, pages={1-21}, language={eng}, issn={1756-994X}, volume={16}, number={Artikel-ID 83}, note={Gesehen am 25.11.2024}, journal={Genome medicine}, doi={10.1186/s13073-024-01357-w}, } @article{UBHD-68749356, author={Kruse, Michael and Seki, Yoshinori and Vuguin, Patricia M. and Du, Xiu Quan and Fiallo, Ariana and Glenn, Alan S. and Singer, Stephan and Breuhahn, Kai and Katz, Ellen B. and Charron, Maureen J.}, title={High-Fat intake during pregnancy and lactation exacerbates high-fat diet-induced complications in male offspring in mice}, year={2013}, pages={3565-3576}, language={eng}, issn={1945-7170}, volume={154}, number={10 vom: Okt.}, note={Gesehen am 16.06.2021}, journal={Endocrinology}, doi={10.1210/en.2012-1877}, } @article{UBHD-69259088, author={Liu, Kaijing and Wehling, Lilija and Wan, Shan and Weiler, Sofia Maria Elisabeth and Tóth, Marcell and Ibberson, David and Marhenke, Silke and Ali, Adnan and Lam, Macrina and Guo, Te and Pinna, Federico and Pedrini, Fabiola and Damle-Vartak, Amruta and Dropmann, Anne and Rose, Fabian and Colucci, Silvia and Cheng, Wenxiang and Bissinger, Michaela and Schmitt, Jennifer and Birner, Patrizia and Poth, Tanja and Angel, Peter and Dooley, Steven and Muckenthaler, Martina and Longerich, Thomas and Vogel, Arndt and Heikenw{\"a}lder, Mathias and Schirmacher, Peter and Breuhahn, Kai}, title={Dynamic YAP expression in the non-parenchymal liver cell compartment controls heterologous cell communication}, year={2024}, pages={1-19}, language={eng}, issn={1420-9071}, volume={81}, note={Gesehen am 01.10.2024}, journal={Cellular and molecular life sciences}, doi={10.1007/s00018-024-05126-1}, } @article{UBHD-68241861, author={Longerich, Thomas and M{\"u}ller, Michael and Breuhahn, Kai and Schirmacher, Peter and Benner, Axel and Heiß, Christiane}, title={Oncogenetic tree modeling of human hepatocarcinogenesis}, year={2012}, pages={575-583}, language={eng}, issn={1097-0215}, volume={130}, number={3}, note={First published: 11 March 2011 ; Gesehen am 11.04.2018}, journal={International journal of cancer}, doi={10.1002/ijc.26063}, } @article{UBHD-68444288, author={Longerich, Thomas and Endris, Volker and Neumann, Olaf and Rempel, Eugen and Kirchner, Martina and Abadi, Zahra and Kriegsmann, Mark and Weiss, Karl Heinz and Breuhahn, Kai and Mehrabi, Arianeb and Weber, Tim and Fr{\"o}hling, Stefan and Pellegrino, Rossella and Budczies, Jan and Schirmacher, Peter and Stenzinger, Albrecht}, title={RSPO2 gene rearrangement}, subtitle={a powerful driver of β-catenin activation in liver tumours}, year={2019}, pages={1287-1296}, language={eng}, issn={1468-3288}, volume={68}, number={7}, note={Published online first 2 February 2019 ; Gesehen am 23.10.2019}, journal={Gut}, doi={10.1136/gutjnl-2018-317632}, } @article{UBHD-68220649, author={Lotz, Joachim and M{\"u}ller, Beat P. and González-Vallinas, Margarita and Warth, Arne and Lahrmann, Bernd and Grabe, Niels and Breuhahn, Kai}, title={Patch-based nonlinear image registration for gigapixel whole slide images}, year={2016}, pages={1812-1819}, language={eng}, issn={1558-2531}, volume={63}, number={9}, note={Date of publication: November 23, 2015 ; Gesehen am 15.02.2018}, journal={IEEE transactions on biomedical engineering}, doi={10.1109/TBME.2015.2503122}, } @book{UBHD-68614974, editor={Schirmacher, Peter and Kauczor, Hans-Ulrich and Breuhahn, Kai and Warth, Arne and Sedlaczek, Oliver}, organization={Universit{\"a}t Heidelberg / Pathologisches Institut}, title={LungSys II Systembiologie des Lungenkrebses - Dynamischen Eigenschaften der fr{\"u}hen Metastasierung und therapeutische Optionen}, subtitle={Schlussbericht : Laufzeit: 01.02.2012-31.07.2015}, publisher={[Universit{\"a}tsklinik Heidelberg, Pathologisches Institut]}, address={Heidelberg}, year={2016}, pages={19 Bl{\"a}tter, 1 ungez{\"a}hltes Blatt}, language={ger}, note={F{\"o}rderkennzeichen BMBF 0316042B. - Verbund-Nummer 01099805 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, keywords={Lungenkrebs / Nicht-kleinzelliges Bronchialkarzinom / Metastase / Signaltransduktion / Bildgebendes Verfahren / Systembiologie / Insulin-like Growth Factor I / Epidermaler Wachstumsfaktor}, } @book{UBHD-68614976, editor={Schirmacher, Peter and Kauczor, Hans-Ulrich and Breuhahn, Kai and Warth, Arne and Sedlaczek, Oliver}, organization={Universit{\"a}t Heidelberg / Pathologisches Institut}, title={LungSys II Systembiologie des Lungenkrebses - Dynamischen Eigenschaften der fr{\"u}hen Metastasierung und therapeutische Optionen}, subtitle={Schlussbericht : Laufzeit: 01.02.2012-31.07.2015}, publisher={[Universit{\"a}tsklinik Heidelberg, Pathologisches Institut]}, address={Heidelberg}, year={2016}, pages={1 Online-Ressource (20 Seiten, 686,87 KB)}, language={ger}, note={F{\"o}rderkennzeichen BMBF 0316042B. - Verbund-Nummer 01099805 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, doi={10.2314/GBV:880541989}, keywords={Lungenkrebs / Nicht-kleinzelliges Bronchialkarzinom / Metastase / Signaltransduktion / Bildgebendes Verfahren / Systembiologie / Insulin-like Growth Factor I / Epidermaler Wachstumsfaktor}, } @article{UBHD-68314827, author={Malz, Mona and Aulmann, Antje and Samarin, Jana and Bissinger, Michaela and Longerich, Thomas and Schmitt, Sabrina and Schirmacher, Peter and Breuhahn, Kai}, title={Nuclear accumulation of seven in absentia homologue-2 supports motility and proliferation of liver cancer cells}, year={2012}, pages={2016-2026}, language={eng}, issn={1097-0215}, volume={131}, number={9}, note={Gesehen am 12.10.2018}, journal={International journal of cancer}, doi={10.1002/ijc.27473}, } @article{UBHD-67819076, author={Malz, Mona and Ganzinger, Matthias and Gretz, Norbert and Schirmacher, Peter and Breuhahn, Kai and Bovet, Michael and Samarin, Jana and Sticht, Carsten and Bissinger, Michaela and R{\"o}ssler, Stephanie and Lorenzo Bermejo, Justo and Renner, Marcus and Singer, Stephan}, title={Overexpression of Far Upstream Element (FUSE) Binding Protein (FBP)-Interacting Repressor (FIR) supports growth of hepatocellular carcinoma}, year={2014}, pages={1241-1250}, language={eng}, issn={1527-3350}, volume={60}, number={4}, note={Gesehen am: 18.05.2015}, journal={Hepatology}, doi={10.1002/hep.27218}, } @article{UBHD-68314838, author={Malz, Mona and Pinna, Federico and Schirmacher, Peter and Breuhahn, Kai}, title={Transcriptional regulators in hepatocarcinogenesis}, subtitle={key integrators of malignant transformation}, year={2012}, pages={186-195}, language={eng}, issn={1600-0641}, volume={57}, number={1}, note={Gesehen am 12.10.2018}, journal={Journal of hepatology}, doi={10.1016/j.jhep.2011.11.029}, } @article{UBHD-68275403, author={Marquard, Simone and Thomann, Stefan and Weiler, Sofia Maria Elisabeth and Sticht, Carsten and Gretz, Norbert and Schirmacher, Peter and Breuhahn, Kai}, title={Nichtautonome Effekte des Onkogens YAP in der Hepatokarzinogenese}, year={2017}, pages={175-179}, language={ger}, issn={1432-1963}, volume={38}, number={Supplement 2}, note={Online publiziert: 10. Oktober 2017 ; Mit englischer Zusammenfassung unter dem Titel: Nonautonomous effects of oncogenic YAP in hepatocarcinogenesis ; Gesehen am 28.06.2018}, journal={Der Pathologe}, doi={10.1007/s00292-017-0361-2}, } @article{UBHD-68735702, author={Marquard, Simone and Thomann, Stefan and Weiler, Sofia Maria Elisabeth and Bissinger, Michaela and Lutz, Teresa and Sticht, Carsten and Tóth, Marcell and Torre, Carolina de la and Gretz, Norbert and Straub, Beate Katharina and Marquardt, Jens and Schirmacher, Peter and Breuhahn, Kai}, title={Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis}, year={2020}, pages={1-15}, language={eng}, issn={1478-811X}, volume={18}, number={Artikel-ID 166}, note={Gesehen am 10.05.2021}, journal={Cell communication and signaling}, doi={10.1186/s12964-020-00634-6}, url={https://doi.org/10.1186/s12964-020-00634-6}, library={UB}, } @article{UBHD-68070305, author={Marquardt, Jens and Gomez-Quiroz, Luis and Arreguin Camacho, Lucrezia O. and Pinna, Federico and Lee, Yun-Han and Kitade, Mitsuteru and Palestino Domínguez, Mayrel and Castven, Darko and Breuhahn, Kai and Conner, Elizabeth A. and Galle, Peter R. and Andersen, Jesper B. and Factor, Valentina M. and Thorgeirsson, Snorri S.}, title={Curcumin effectively inhibits oncogenic NF-kB signaling and restrains stemness features in liver cancer}, year={2015}, pages={661-669}, language={eng}, issn={1600-0641}, volume={63}, number={3}, note={Gesehen am 10.01.2017}, journal={Journal of hepatology}, doi={10.1016/j.jhep.2015.04.018}, } @article{UBHD-68323679, author={Milewski, David and Dienemann, Hendrik and Warth, Arne and Breuhahn, Kai}, title={FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas}, year={2017}, pages={21 S.}, language={eng}, issn={1553-7404}, volume={13}, note={Gesehen am 31.10.2018}, journal={PLoS Genetics}, doi={10.1371/journal.pgen.1007097}, } @article{UBHD-68254482, author={M{\"u}hlich, Susanne and Singer, Stephan and Breuhahn, Kai}, title={The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1}, year={2012}, pages={3913-3923}, language={eng}, issn={1476-5594}, volume={31}, number={35}, note={Published online: 05 December 2011 ; Gesehen am 24.05.2018}, journal={Oncogene}, doi={10.1038/onc.2011.560}, } @article{UBHD-68034664, author={M{\"u}ller, Benedikt and Bovet, Michael and Stichel, Damian and Malz, Mona and González-Vallinas, Margarita and Middleton, Alistair and Ehemann, Volker and Schmitt, Jennifer and Muley, Thomas and Meister, Michael and Herpel, Esther and Singer, Stephan and Warth, Arne and Schirmacher, Peter and Matth{\"a}us, Franziska and Breuhahn, Kai}, title={Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer (NSCLC) cells}, year={2015}, pages={390-401}, language={eng}, issn={1096-9896}, volume={237}, number={3}, note={Gesehen am 29.09.2016}, journal={The journal of pathology}, doi={10.1002/path.4588}, } @article{UBHD-68617775, author={Namineni, Sukumar and O'Connor, Tracy and Faure-Dupuy, Suzanne and Johansen, Pal and Riedl, Tobias and Liu, Kaijing and Xu, Haifeng and Singh, Indrabahadur and Shinde, Prashant and Li, Fanghui and Pandyra, Aleksandra and Sharma, Piyush and Ringelhan, Marc and Muschaweckh, Andreas and Borst, Katharina and Blank, Patrick and Lampl, Sandra and Neuhaus, Katharina and Durantel, David and Farhat, Rayan and Weber, Achim and Lenggenhager, Daniela and K{\"u}ndig, Thomas M. and St{\"a}heli, Peter and Protzer, Ulrike and Wohlleber, Dirk and Holzmann, Bernhard and Binder, Marco and Breuhahn, Kai and Heikenw{\"a}lder, Mathias}, title={A dual role for hepatocyte-intrinsic canonical NF-[kappa]B signaling in virus control}, year={2020}, pages={960-975}, language={eng}, issn={1600-0641}, volume={72}, number={5}, note={Gesehen am 16.07.2020 ; Im Titel ist "kappa" als griechischer Buchstabe dargestellt}, journal={Journal of hepatology}, doi={10.1016/j.jhep.2019.12.019}, } @book{UBHD-68614970, organization={Universit{\"a}t Heidelberg / Pathologisches Institut}, title={Netzwerk Virtuelle Leber - Virtual Liver Network (VLN)}, subtitle={Schlussbericht : Laufzeit: 01.02.2012-31.12.2015}, publisher={Universit{\"a}tsklinik Heidelberg, Pathologisches Institut}, address={Heidelberg}, year={2016}, pages={23 Bl{\"a}tter, 1 ungez{\"a}hltes Blatt}, language={ger}, note={F{\"o}rderkennzeichen BMBF 0315761. - Verbund-Nummer 01078981 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, keywords={Leberepithelzelle / Leber / Systembiologie / Tiermodell}, } @book{UBHD-68614972, organization={Universit{\"a}t Heidelberg / Pathologisches Institut}, title={Netzwerk Virtuelle Leber - Virtual Liver Network (VLN)}, subtitle={Schlussbericht : Laufzeit: 01.02.2012-31.12.2015}, publisher={Universit{\"a}tsklinik Heidelberg, Pathologisches Institut}, address={Heidelberg}, year={2016}, pages={1 Online-Ressource (24 Seiten, 2,37 MB)}, language={ger}, note={F{\"o}rderkennzeichen BMBF 0315761. - Verbund-Nummer 01078981 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, doi={10.2314/GBV:873062175}, keywords={Leberepithelzelle / Leber / Systembiologie / Tiermodell}, } @article{UBHD-68934813, author={Pellegrino, Rossella and Castoldi, Mirco and Ticconi, Fabio and Skawran, Britta and Budczies, Jan and Rose, Fabian and Schwab, Constantin and Breuhahn, Kai and Neumann, Ulf P. and Gaisa, Nadine T. and Loosen, Sven H. and Luedde, Tom and Costa, Ivan G. and Longerich, Thomas}, title={LINC00152 drives a competing endogenous RNA network in human hepatocellular carcinoma}, year={2022}, pages={1-20}, language={eng}, issn={2073-4409}, volume={11}, note={Gesehen am 27.06.2022}, journal={Cells}, doi={10.3390/cells11091528}, } @article{UBHD-68314283, author={Pinna, Federico and Bissinger, Michaela and Beuke, Katharina and Huber, Nicolas Peter and Kummer, Ursula and Schirmacher, Peter and Sahle, Sven and Breuhahn, Kai}, title={A20/TNFAIP3 discriminates tumor necrosis factor (TNF)-induced NF-[kappa]B from JNK pathway activation in hepatocytes}, year={2017}, pages={13 S.}, language={eng}, issn={1664-042X}, volume={8}, number={Artikel-ID 610}, note={Gesehen am 11.10.2018}, journal={Frontiers in physiology}, doi={10.3389/fphys.2017.00610}, } @article{UBHD-68122302, author={Pinna, Federico and Sahle, Sven and Beuke, Katharina and Bissinger, Michaela and Aydin, Selcan and D'Alessandro, Lorenza and Gauges, Ralph and Raue, Andreas and Timmer, Jens and Klingm{\"u}ller, Ursula and Schirmacher, Peter and Kummer, Ursula and Breuhahn, Kai}, title={A systems biology study on NF[kappa]B signaling in primary mouse hepatocytes}, year={2012}, pages={14 S.}, language={eng}, issn={1664-042X}, volume={3}, note={Gesehen am 23.05.2017}, journal={Frontiers in physiology}, doi={10.3389/fphys.2012.00466}, } @article{UBHD-68217738, author={Pl{\"o}ger, Carolin and Waldburger, Nina and Fraas, Angelika and Goeppert, Benjamin and Pusch, Stefan and Breuhahn, Kai and Schirmacher, Peter and R{\"o}ssler, Stephanie}, title={Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma}, year={2016}, pages={828-842}, language={eng}, issn={1527-3350}, volume={64}, number={3}, note={Gesehen am 06.02.2018}, journal={Hepatology}, doi={10.1002/hep.28684}, } @article{UBHD-68967785, author={Pl{\"o}ger, Carolin and Schreck, Johannes and Huth, Thorben and Fraas, Angelika and Albrecht, Thomas and Charbel, Alphonse and Ji, Junfang and Singer, Stephan and Breuhahn, Kai and Pusch, Stefan and K{\"o}hler, Bruno Christian and Springfeld, Christoph and Schirmacher, Peter and Mehrabi, Arianeb and Goeppert, Benjamin and R{\"o}ssler, Stephanie}, title={STAT1 and STAT3 exhibit a crosstalk and are associated with increased inflammation in hepatocellular carcinoma}, year={2022}, pages={16 S.}, language={eng}, issn={2072-6694}, volume={14}, note={Published: 23 February 2022 ; Gesehen am 27.09.2022}, journal={Cancers}, doi={10.3390/cancers14051154}, } @article{UBHD-67515306, author={Safferling, Kai and S{\"u}tterlin, Thomas and Westphal, Kathi and Ernst, Claudia and Breuhahn, Kai and James, Merlin and J{\"a}ger, Dirk and Halama, Niels and Grabe, Niels}, title={Wound healing revised}, subtitle={novel reepithelialization mechanism revealed by in vitro and in silico models}, year={2013}, pages={691-709}, language={eng}, issn={1540-8140}, volume={203}, number={4}, note={Gesehen am 20.12.2013}, journal={The journal of cell biology}, doi={10.1083/jcb.201212020}, } @article{UBHD-68871400, author={Salnikova, Olga and Breuhahn, Kai and Hartmann, Natalie and Schmidt, Jan and Ryschich, Eduard}, title={Endothelial plasticity governs the site-specific leukocyte recruitment in hepatocellular cancer}, year={2013}, pages={2372-2382}, language={eng}, issn={1097-0215}, volume={133}, number={10 vom: 15. Nov.}, note={Gesehen am 27.01.2022}, journal={International journal of cancer}, doi={10.1002/ijc.28268}, } @article{UBHD-68367449, author={Samarin, Jana and Malz, Mona and R{\"o}ssler, Stephanie and Singer, Stephan and Bissinger, Michaela and Dooley, Steven and Schirmacher, Peter and Breuhahn, Kai}, title={PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells}, year={2016}, pages={813-826}, language={eng}, issn={1527-3350}, volume={63}, number={3}, note={Gesehen am 07.03.2019 ; First published: 24 November 2015}, journal={Hepatology}, doi={10.1002/hep.28357}, } @article{UBHD-69183534, author={Scherr, Anna-Lena and Nader, Luisa and Xu, Kaiyu and Elssner, Christin and Ridder, Dirk A. and Nichetti, Federico and Mastel, Manuel and Fritzsche, Sarah and Kelmendi, Eblina and Schmitt, Nathalie and Hoffmeister-Wittmann, Paula and Hoffmeister-Wittmann, Paula and Weiler, Sofia Maria Elisabeth and Korell, Felix and Albrecht, Thomas and Schwab, Maximilian and Isele, Hanna and Kessler, Annika and H{\"u}llein, Jennifer and Seretny, Agnieszka and Ye, Liangtao and Urbanik, Toni and Welte, Stefan and Leblond, Anne-Laure and Heilig, Christoph E. and Rahbari, Mohammad and Ali, Sheikh Adnan and Gallage, Suchira and Lenoir, Bénédicte and Wilhelm, Nina and G{\"a}rtner, Ulrike and Ogrodnik, Simon J. and Springfeld, Christoph and Tschaharganeh, Darjus-Felix and Fr{\"o}hling, Stefan and Longerich, Thomas and Schulze-Bergkamen, Henning and J{\"a}ger, Dirk and Brandl, Lydia and Schirmacher, Peter and Straub, Beate Katharina and Weber, Achim and De Toni, Enrico N. and Goeppert, Benjamin and Heikenwalder, Mathias and Jackstadt, René-Filip and R{\"o}ssler, Stephanie and Breuhahn, Kai and K{\"o}hler, Bruno Christian}, title={Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC}, year={2024}, pages={278-294}, language={eng}, issn={1527-3350}, volume={80}, number={2}, note={Gesehen am 19.02.2024}, journal={Hepatology}, doi={10.1097/HEP.0000000000000657}, } @article{UBHD-68757651, author={Schmitt, Sabrina and Safferling, Kai and Westphal, Kathi and Hrabowski, Manuel and M{\"u}ller, Ute and Angel, Peter and Wiechert, Lars and Ehemann, Volker and M{\"u}ller, Benedikt and Holland-Cunz, Stefan and Stichel, Damian and Harder, Nathalie and Rohr, Karl and Germann, G{\"u}nter and Matth{\"a}us, Franziska and Schirmacher, Peter and Grabe, Niels and Breuhahn, Kai}, title={Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration}, year={2013}, pages={1-15}, language={eng}, issn={1932-6203}, volume={8}, note={Gesehen am 08.07.2021}, journal={PLOS ONE}, doi={10.1371/journal.pone.0075075}, } @article{UBHD-68985592, author={Sch{\"u}ller, Stefanie and Sieker, Jan and Riemenschneider, Philip and K{\"o}hler, Bianca and Drucker, Elisabeth and Weiler, Sofia Maria Elisabeth and Dauch, Daniel and Sticht, Carsten and Goeppert, Benjamin and R{\"o}ssler, Stephanie and Ribback, Silvia and Breuhahn, Kai and Fend, Falko and Dombrowski, Frank and Singer, Kerstin and Singer, Stephan}, title={HELLS Is negatively regulated by wild-type P53 in liver cancer by a mechanism involving P21 and FOXM1}, year={2022}, pages={1-20}, language={eng}, issn={2072-6694}, volume={14}, note={Gesehen am 15.11.2022}, journal={Cancers}, doi={10.3390/cancers14020459}, } @article{UBHD-68573834, author={Shatirishvili, Marine and Burk, Alexandra Serena and Breuhahn, Kai and Tanaka, Motomu}, title={Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress}, year={2016}, pages={12 S.}, language={eng}, issn={2041-4889}, volume={7(2016}, note={Gesehen am 06.05.2020}, journal={Cell death & disease}, doi={10.1038/cddis.2016.342}, } @article{UBHD-67387612, author={Singer, Stephan and Breuhahn, Kai and Neumann, Olaf and Longerich, Thomas and Heß, Jochen and Schirmacher, Peter}, title={Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes}, year={2012}, pages={799-810}, language={eng}, issn={1097-2765}, volume={48}, number={5}, journal={Molecular cell}, } @article{UBHD-68244218, author={Stichel, Damian and Middleton, Alistair and M{\"u}ller, Benedikt and Depner, Sofia and Klingm{\"u}ller, Ursula and Breuhahn, Kai and Matth{\"a}us, Franziska}, title={An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors}, year={2017}, pages={5}, language={eng}, issn={2056-7189}, volume={3}, number={1}, note={Gesehen am 01.09.2020}, journal={npj Systems biology and applications}, doi={10.1038/s41540-017-0006-3}, } @article{UBHD-68248408, author={Straßburger, Katrin and Pinna, Federico and Breuhahn, Kai and Teleman, Aurelio A.}, title={Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP}, year={2012}, pages={187-196}, language={eng}, issn={1095-564X}, volume={367}, number={2}, note={Gesehen am 26.08.2020}, journal={Developmental biology}, doi={10.1016/j.ydbio.2012.05.008}, } @article{UBHD-69117946, author={Straub, Beate Katharina and Herpel, Esther and Singer, Stephan and Zimbelmann, Ralf and Breuhahn, Kai and Macher-G{\"o}ppinger, Stephan and Warth, Arne and Lehmann-Koch, Judith and Longerich, Thomas and Heid, Hans and Schirmacher, Peter}, title={Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis}, year={2010}, pages={480-492}, language={eng}, issn={1530-0285}, volume={23}, number={3 vom: M{\"a}rz}, note={Gesehen am 01.09.2023}, journal={Modern pathology}, doi={10.1038/modpathol.2009.191}, } @article{UBHD-69113532, author={Tang, Yingyue and Thiess, Lena and Weiler, Sofia Maria Elisabeth and Tóth, Marcell and Rose, Fabian and Merker, Sabine and Ruppert, Thomas and Schirmacher, Peter and Breuhahn, Kai}, title={α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration}, year={2023}, pages={1-19}, language={eng}, issn={1478-811X}, volume={21}, number={Artikel-ID 162}, note={Ver{\"o}ffentlicht: 28. Juni 2023 ; Gesehen am 17.08.2023}, journal={Cell communication and signaling}, doi={10.1186/s12964-023-01169-2}, url={https://doi.org/10.1186/s12964-023-01169-2}, library={UB}, } @article{UBHD-68579819, author={Textor, Sonja and Boßler, Felicitas Martha and Henrich, Kai-Oliver and Gartlgruber, Moritz and Pollmann, Julia and Fiegler, Nathalie and Arnold, Annette and Westermann, Frank and Waldburger, Nina and Breuhahn, Kai and Golfier, Sven and Witzens-Harig, Mathias and Cerwenka, Adelheid}, title={The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells}, year={2016}, pages={12 S.}, language={eng}, issn={2162-402X}, volume={5(2016}, note={Gesehen am 20.05.2020}, journal={OncoImmunology}, doi={10.1080/2162402X.2015.1116674}, } @article{UBHD-69107510, author={Thomann, Stefan and Weiler, Sofia Maria Elisabeth and Wei, Teng and Sticht, Carsten and Torre, Carolina de la and Tóth, Marcell and Rose, Fabian and Tang, Yingyue and Ritz, Thomas and Ball, Claudia and Glimm, Hanno and Ryschich, Eduard and Schirmacher, Peter and Breuhahn, Kai}, title={YAP-induced Ccl2 expression is associated with a switch in hepatic macrophage identity and vascular remodelling in liver cancer}, year={2021}, pages={3011-3023}, language={eng}, issn={1478-3231}, volume={41}, number={12}, note={Gesehen am 08.08.2023}, journal={Liver international}, doi={10.1111/liv.15048}, url={https://doi.org/10.1111/liv.15048}, library={UB}, } @article{UBHD-68909992, author={Thomann, Stefan and Weiler, Sofia Maria Elisabeth and Marquard, Simone and Rose, Fabian and Ball, Claudia R. and Tóth, Marcell and Wei, Teng and Sticht, Carsten and Fritzsche, Sarah and R{\"o}ssler, Stephanie and Torre, Carolina de la and Ryschich, Eduard and Ermakova, Olga and Mogler, Carolin and Kazdal, Daniel and Gretz, Norbert and Glimm, Hanno and Rempel, Eugen and Schirmacher, Peter and Breuhahn, Kai}, title={YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis}, year={2020}, pages={5502-5514}, language={eng}, issn={1538-7445}, volume={80}, number={24}, note={Gesehen am 23.04.2022}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-20-0242}, } @article{UBHD-68803779, author={Tóth, Marcell and Wehling, Lilija and Thiess, Lena and Rose, Fabian and Schmitt, Jennifer and Weiler, Sofia Maria Elisabeth and Sticht, Carsten and Torre, Carolina de la and Rausch, Melina and Albrecht, Thomas and Grabe, Niels and Duwe, Lea and Andersen, Jesper B. and K{\"o}hler, Bruno Christian and Springfeld, Christoph and Mehrabi, Arianeb and Kulu, Yakup and Schirmacher, Peter and R{\"o}ssler, Stephanie and Goeppert, Benjamin and Breuhahn, Kai}, title={Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma}, year={2021}, pages={1-14}, language={eng}, issn={1471-2407}, volume={21}, number={Artikel-ID 1079}, note={Gesehen am 22.11.2021}, journal={BMC cancer}, doi={10.1186/s12885-021-08794-5}, url={https://doi.org/10.1186/s12885-021-08794-5}, library={UB}, } @article{UBHD-68877718, author={Tschaharganeh, Darjus-Felix and Chen, Xin and Latzko, Philipp and Malz, Mona and Gaida, Matthias and Felix, Klaus M. and Ladu, Sara and Singer, Stephan and Pinna, Federico and Gretz, Norbert and Sticht, Carsten and Tomasi, Maria Lauda and Delogu, Salvatore and Evert, Matthias and Fan, Biao and Ribback, Silvia and Jiang, Lijie and Brozzetti, Stefania and Bergmann, Frank and Dombrowski, Frank and Schirmacher, Peter and Calvisi, Diego Francesco and Breuhahn, Kai}, title={Yes-associated protein up-regulates Jagged-1 and activates the NOTCH pathway in human hepatocellular carcinoma}, year={2013}, pages={1530-1542}, language={eng}, issn={1528-0012}, volume={144}, number={7}, note={Gesehen am 14.02.2022}, journal={Gastroenterology}, doi={10.1053/j.gastro.2013.02.009}, } @article{UBHD-67454905, author={Tschaharganeh, Darjus-Felix and Breuhahn, Kai and Latzko, Philipp and Malz, Mona and Gaida, Matthias and Felix, Klaus M. and Singer, Stephan and Gretz, Norbert and Sticht, Carsten and Bergmann, Frank and Schirmacher, Peter}, title={Yes-associated protein up-regulates Jagged-1 and activates the NOTCH pathway in human hepatocellular carcinoma}, year={2013}, pages={1530-1542}, language={eng}, issn={0016-5085}, volume={144}, number={7}, journal={Gastroenterology}, } @article{UBHD-68284467, author={Wachter, David Lukas and Breuhahn, Kai}, title={Insulin-like growth factor II mRNA-binding protein 3 (IMP3) expression in hepatocellular carcinoma}, subtitle={a clinicopathological analysis with emphasis on diagnostic value}, year={2012}, pages={278-286}, language={eng}, issn={1365-2559}, volume={60}, number={2}, note={First published: 23 December 2011 ; Gesehen am 11.07.2018}, journal={Histopathology}, doi={10.1111/j.1365-2559.2011.04091.x}, } @article{UBHD-68364609, author={Waly, Amr A. and Breuhahn, Kai}, title={Methylation in MIRLET7A3 gene induces the expression of IGF-II and its mRNA binding proteins IGF2BP-2 and 3 in hepatocellular carcinoma}, year={2019}, language={eng}, issn={1664-042X}, volume={9(2019) Artikel-Nummer 01918}, number={10 Seiten}, note={Gesehen am 01.03.2019}, journal={Frontiers in physiology}, doi={10.3389/fphys.2018.01918}, } @article{UBHD-68329794, author={Wan, Shan and Weiler, Sofia Maria Elisabeth and Rupp, Christian and Tóth, Marcell and Sticht, Carsten and Singer, Stephan and Thomann, Stefan and R{\"o}ssler, Stephanie and Schmitt, Jennifer and Gretz, Norbert and Tschaharganeh, Darjus-Felix and Schirmacher, Peter and Pinna, Federico and Breuhahn, Kai}, title={Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness}, year={2018}, pages={1842-1856}, language={eng}, issn={1527-3350}, volume={67}, number={5}, note={Accepted manuscript online: 20 November 2017 ; Gesehen am 19.11.2018}, journal={Hepatology}, doi={10.1002/hep.29669}, } @article{UBHD-68997083, author={Wehling, Lilija and Keegan, Liam and Fernández-Palanca, Paula and Hassan, Reham and Ghallab, Ahmed and Schmitt, Jennifer and Tang, Yingyue and Le Marois, Maxime and R{\"o}ssler, Stephanie and Schirmacher, Peter and Kummer, Ursula and Hengstler, Jan G and Sahle, Sven and Breuhahn, Kai}, title={Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury}, year={2022}, pages={1-28}, language={eng}, issn={2050-084X}, volume={11}, number={Artikel-ID e78540}, note={Gesehen am 14.12.2022}, journal={eLife}, doi={10.7554/eLife.78540}, } @article{UBHD-68313268, author={Weiler, Sofia Maria Elisabeth and Pinna, Federico and Lutz, Teresa and Sticht, Carsten and Knaub, Maria and Thomann, Stefan and Bissinger, Michaela and Wan, Shan and R{\"o}ssler, Stephanie and Gretz, Norbert and Bergmann, Frank and Singer, Stephan and Schirmacher, Peter and Breuhahn, Kai}, title={Induction of chromosome instability by activation of yes-associated protein and forkhead box M1 in liver cancer}, year={2017}, pages={2037-2051.e22}, language={eng}, issn={1528-0012}, volume={152}, number={8}, note={Gesehen am 09.10.2018}, journal={Gastroenterology}, doi={10.1053/j.gastro.2017.02.018}, } @article{UBHD-69233102, author={Weiler, Sofia Maria Elisabeth and Bissinger, Michaela and Rose, Fabian and von Bubnoff, Fabian and Lutz, Teresa and Ori, Alessandro and Schirmacher, Peter and Breuhahn, Kai}, title={SEPTIN10-mediated crosstalk between cytoskeletal networks controls mechanotransduction and oncogenic YAP/TAZ signaling}, year={2024}, pages={1-13}, language={eng}, issn={1872-7980}, volume={584(2024) vom: M{\"a}rz}, number={Artikel-ID 216637}, note={Online verf{\"u}gbar: 17. Januar 2024, Artikelversion: 25. Januar 2024 ; Gesehen am 12.07.2024}, journal={Cancer letters}, doi={10.1016/j.canlet.2024.216637}, } @article{UBHD-68562616, author={Weiler, Sofia Maria Elisabeth and Lutz, Teresa and Bissinger, Michaela and Sticht, Carsten and Knaub, Maria and Gretz, Norbert and Schirmacher, Peter and Breuhahn, Kai}, title={TAZ target gene ITGAV regulates invasion and feeds back positively on YAP and TAZ in liver cancer cells}, year={2020}, pages={164-175}, language={eng}, issn={1872-7980}, volume={473}, note={Gesehen am 07.04.2020}, journal={Cancer letters}, doi={10.1016/j.canlet.2019.12.044}, } @article{UBHD-68411712, author={Wei, Teng and Weiler, Sofia Maria Elisabeth and Tóth, Marcell and Sticht, Carsten and Lutz, Teresa and Thomann, Stefan and Torre, Carolina de la and Straub, Beate Katharina and Merker, Sabine and Ruppert, Thomas and Marquardt, Jens and Singer, Stephan and Gretz, Norbert and Schirmacher, Peter and Breuhahn, Kai}, title={YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells}, year={2019}, pages={5541--5550}, language={eng}, issn={1476-5594}, volume={38}, number={27}, note={Gesehen am 24.07.2019}, journal={Oncogene}, doi={10.1038/s41388-019-0801-y}, } @article{UBHD-67939398, author={Welte, Stefan Ezechiel and Urbanik, Toni and Elßner, Christin and Kautz, Nicole and K{\"o}hler, Bruno Christian and Waldburger, Nina and Lorenzo Bermejo, Justo and Pinna, Federico and Weiss, Karl Heinz and Schemmer, Peter and J{\"a}ger, Dirk and Longerich, Thomas and Breuhahn, Kai and Schulze-Bergkamen, Henning}, title={Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma}, year={2014}, pages={9 S.}, language={eng}, issn={1932-6203}, volume={9(2014}, note={Gesehen am 10.02.2016}, journal={PLOS ONE}, doi={10.1371/journal.pone.0110591}, } @article{UBHD-69328597, author={Wesener, Marie C. and Weiler, Sofia Maria Elisabeth and Bissinger, Michaela and Klessinger, Tobias F. and Rose, Fabian and Merker, Sabine and Luzarowski, Marcin and Ruppert, Thomas and Helm, Barbara and Klingm{\"u}ller, Ursula and Schirmacher, Peter and Breuhahn, Kai}, title={CRKL enhances YAP signaling through binding and JNK/JUN pathway activation in liver cancer}, year={2024}, pages={1-18}, language={eng}, issn={1422-0067 and 1661-6596}, volume={25}, note={Gesehen am 07.04.2025}, journal={International journal of molecular sciences}, doi={10.3390/ijms25158549}, } @article{UBHD-68381801, author={Winkler, Juliane and R{\"o}ssler, Stephanie and Sticht, Carsten and Drucker, Elisabeth and Holzer, Kerstin and Eiteneuer, Eva and Herpel, Esther and Breuhahn, Kai and Gretz, Norbert and Schirmacher, Peter and Singer, Stephan}, title={Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC)}, year={2016}, pages={22883-22892}, language={eng}, issn={1949-2553}, volume={7}, number={16}, note={Gesehen am 23.04.2019}, journal={OncoTarget}, doi={10.18632/oncotarget.8256}, } @article{UBHD-67846345, author={Winkler, Juliane and Gretz, Norbert and Schirmacher, Peter and Singer, Stephan and Holzer, Kerstin and Sticht, Carsten and Eiteneuer, Eva and Pinna, Federico and Ehemann, Volker and Breuhahn, Kai and Longerich, Thomas and Lorenzo Bermejo, Justo}, title={Prosurvival function of the cellular apoptosis susceptibility/importin-alpha 1 transport cycle is repressed by p53 in liver cancer}, year={2014}, pages={884-895}, language={eng}, issn={1527-3350}, volume={60}, number={3}, note={Gesehen am: 15.07.2015}, journal={Hepatology}, doi={10.1002/hep.27207}, } @article{UBHD-68205136, author={Wolf, Benita and Breuhahn, Kai}, title={Inducing differentiation of premalignant hepatic cells as a novel therapeutic strategy in hepatocarcinoma}, year={2016}, pages={5550-5561}, language={eng}, issn={1538-7445}, volume={76}, number={18}, note={Gesehen am 21.12.2017}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-15-3453}, } @article{UBHD-68569338, author={Yin, Yi and Sedlaczek, Oliver and M{\"u}ller, Benedikt and Warth, Arne and González-Vallinas, Margarita and Lahrmann, Bernd and Grabe, Niels and Kauczor, Hans-Ulrich and Breuhahn, Kai and Vignon-Clementel, Irene E. and Drasdo, Dirk}, title={Tumor cell load and heterogeneity estimation from diffusion-weighted mri calibrated with histological data}, subtitle={an example from lung cancer}, year={2018}, pages={35-46}, language={eng}, issn={1558-254X}, volume={37}, number={1}, note={Date of publication: 27 April 2017 ; Gesehen am 22.04.2020}, journal={IEEE transactions on medical imaging}, doi={10.1109/TMI.2017.2698525}, }