@article{UBHD-68618528, author={Bandapalli, Obul Reddy and Sch{\"u}ssele, Stephanie and Kunz, Joachim and Rausch, Tobias and St{\"u}tz, Adrian M. and Tal, Noa and Geron, Ifat and Gershman, Nava and Izraeli, Shai and Eilers, Juliane and Vaezipour, Nina and Kirschner-Schwabe, Renate and Hof, Jana and Stackelberg, Arend von and Schrappe, Martin and Stanulla, Martin and Zimmermann, Martin and K{\"o}hler, Rolf and Avigad, Smadar and Handgretinger, Rupert and Frismantas, Viktoras and Bourquin, Jean Pierre and Bornhauser, Beat and Korbel, Jan Oliver and Muckenthaler, Martina and Kulozik, Andreas}, title={The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse}, year={2014}, pages={e188-e192}, language={eng}, issn={1592-8721}, volume={99}, number={10}, note={Gesehen am 20.07.2020}, journal={Haematologica}, doi={10.3324/haematol.2014.104992}, } @article{UBHD-68654912, author={Bandapalli, Obul Reddy and Zimmermann, Martin and Kox, Corinne and Stanulla, Martin and Schrappe, Martin and Ludwig, Wolf-Dieter and K{\"o}hler, Rolf and Muckenthaler, Martina and Kulozik, Andreas}, title={NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia}, year={2013}, pages={928-936}, language={eng}, issn={1592-8721}, volume={98}, number={6}, note={Gesehen am 28.10.2020}, journal={Haematologica, the hematology journal}, doi={10.3324/haematol.2012.073585}, } @article{UBHD-68320615, author={Bartram, Claus R. and K{\"o}hler, Rolf}, title={Acute lymphoblastic leukemia in children}, subtitle={treatment planning via minimal residual disease assessment}, year={2012}, pages={652-658}, language={eng}, issn={1866-0452}, volume={109}, number={40}, note={Gesehen am 24.10.2018}, journal={Deutsches {\"A}rzteblatt international}, doi={10.3238/arztebl.2012.0652}, } @article{UBHD-68894640, author={Bartram, Thies and Sch{\"u}tte, Peter and M{\"o}ricke, Anja and Houlston, Richard and Ellinghaus, Eva and Zimmermann, Martin and Bergmann, Anke Katharina and L{\"o}scher, Britt-Sabina and Klein, Norman and Hinze, Laura and Junk, Stefanie V. and Forster, Michael and Bartram, Claus R. and K{\"o}hler, Rolf and Franke, Andre and Schrappe, Martin and Kratz, Christian Peter and Cario, Gunnar and Stanulla, Martin}, title={Genetic variation in ABCC4 and CFTR and acute pancreatitis during treatment of pediatric acute lymphoblastic leukemia}, year={2021}, pages={1-17}, language={eng}, issn={2077-0383}, volume={10}, note={Gesehen am 04.05.2022}, journal={Journal of Clinical Medicine}, doi={10.3390/jcm10214815}, } @article{UBHD-69072540, author={Bokkasa, Rashmi Prasad and Hosking, Fay J. and Vijayakrishnan, Jayaram and Papaemmanuil, Elli and K{\"o}hler, Rolf and Greaves, Mel and Sheridan, Eamonn and Gast, Andreas and Kinsey, Sally E. and Lightfoot, Tracy and Roman, Eve and Taylor, Malcolm and Pritchard-Jones, Kathy and Stanulla, Martin and Schrappe, Martin and Bartram, Claus R. and Houlston, Richard S. and Kumar, Rajiv and Hemminki, Kari}, title={Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood}, year={2010}, pages={1765-1767}, language={eng}, issn={1528-0020}, volume={115}, number={9 vom: M{\"a}rz}, note={Online vorver{\"o}ffentlicht als "Blood First Edition paper": 30. Dezember 2009 ; Gesehen am 05.05.2023}, journal={Blood}, doi={10.1182/blood-2009-09-241513}, } @article{UBHD-69082949, author={Conter, Valentino and Bartram, Claus R. and Valsecchi, Maria Grazia and Schrauder, André and Panzer-Gr{\"u}mayer, Renate and M{\"o}ricke, Anja and Aricò, Maurizio and Zimmermann, Martin and Mann, Georg and De Rossi, Giulio and Stanulla, Martin and Locatelli, Franco and Basso, Giuseppe and Niggli, Felix and Barisone, Elena and Henze, G{\"u}nter and Ludwig, Wolf-Dieter and Haas, Oskar A. and Cazzaniga, Giovanni and K{\"o}hler, Rolf and Silvestri, Daniela and Bradtke, Jutta and Parasole, Rosanna and Beier, Rita and van Dongen, Jacques J. M. and Biondi, Andrea and Schrappe, Martin}, title={Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia}, subtitle={results in 3184 patients of the AIEOP-BFM ALL 2000 study}, year={2010}, pages={3206-3214}, language={eng}, issn={1528-0020}, volume={115}, number={16}, note={Gesehen am 06.06.2023}, journal={Blood}, doi={10.1182/blood-2009-10-248146}, } @article{UBHD-68674392, author={D{\"o}rge, Petra and Meissner, Barbara and Zimmermann, Martin and M{\"o}ricke, Anja and Schrauder, André and Bouquin, Jean-Pierre and Schewe, Denis and Harbott, Jochen and Teigler-Schlegel, Andrea and Ratei, Richard and Ludwig, Wolf-Dieter and K{\"o}hler, Rolf and Bartram, Claus R. and Schrappe, Martin and Stanulla, Martin and Cario, Gunnar}, title={IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol}, year={2013}, pages={428-432}, language={eng}, issn={1592-8721}, volume={98}, number={3}, note={Gesehen am 17.12.2020}, journal={Haematologica, the hematology journal}, doi={10.3324/haematol.2011.056135}, } @article{UBHD-68902996, author={Eckert, Cornelia and Flohr, T. and K{\"o}hler, Rolf and Hagedorn, N. and Moericke, A. and Stanulla, M. and Kirschner-Schwabe, R. and Cario, G. and Stackelberg, Av and Bartram, Claus R. and Henze, G. and Schrappe, M. and Schrauder, A.}, title={Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment}, year={2011}, pages={1305-1313}, language={eng}, issn={1476-5551}, volume={25}, number={8}, note={Gesehen am 04.04.2022}, journal={Leukemia}, doi={10.1038/leu.2011.89}, } @article{UBHD-68409329, author={Hoffmann, Jana and K{\"o}hler, Rolf}, title={High sensitivity and clonal stability of the genomic fusion as single marker for response monitoring in ETV6-RUNX1-positive acute lymphoblastic leukemia}, year={2019}, pages={11 S.}, language={eng}, issn={1545-5017}, volume={66(2019}, note={Gesehen am 16.07.2019}, journal={Pediatric blood & cancer}, doi={10.1002/pbc.27780}, } @book{UBHD-68564115, author={Jauch, Anna and Hinderhofer, Katrin and K{\"o}hler, Rolf}, organization={Universit{\"a}t Heidelberg / Institut f{\"u}r Humangenetik}, title={Genomische Analysen monoklonaler Plasmazellen zur Verbesserung des Verst{\"a}ndnisses der Amyloidbildung und Prognose der Leichtketten Amyloidose}, subtitle={Schlussbericht BMBF-Fkz: 1GM1107F =}, publisher={Institut f{\"u}r Humangenetik, Universit{\"a}t Heidelberg}, address={Heidelberg}, year={2017}, pages={18 ungez{\"a}hlte Seiten}, language={ger}, note={F{\"o}rderkennzeichen BMBF 01GM1107F. - Verbund-Nummer 01120185 ; Titel, Autoren und durchf{\"u}hrende Institution dem Berichtsblatt entnommen ; Paralleltitel dem englischen Berichtsblatt entnommen ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, keywords={Amyloidose / Immunglobuline / Plasmazelle / Molekulare Medizin / Fluoreszenz-in-situ-Hybridisierung / Interphase}, } @book{UBHD-68564116, author={Jauch, Anna and Hinderhofer, Katrin and K{\"o}hler, Rolf}, organization={Universit{\"a}t Heidelberg / Institut f{\"u}r Humangenetik}, title={Genomische Analysen monoklonaler Plasmazellen zur Verbesserung des Verst{\"a}ndnisses der Amyloidbildung und Prognose der Leichtketten Amyloidose}, subtitle={Schlussbericht BMBF-Fkz: 1GM1107F}, publisher={Institut f{\"u}r Humangenetik, Universit{\"a}t Heidelberg}, address={Heidelberg}, year={2017}, pages={1 Online-Ressource (17 Seiten, 3,31 MB)}, language={ger}, note={F{\"o}rderkennzeichen BMBF 01GM1107F. - Verbund-Nummer 01120185 ; Titel, Autoren und durchf{\"u}hrende Institution dem Berichtsblatt entnommen ; Paralleltitel dem englischen Berichtsblatt entnommen ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, doi={10.2314/GBV:892774924}, keywords={Amyloidose / Immunglobuline / Plasmazelle / Molekulare Medizin / Fluoreszenz-in-situ-Hybridisierung / Interphase}, } @article{UBHD-69054572, author={Junk, Stefanie Verena and Schaeffeler, Elke and Zimmermann, Martin and M{\"o}ricke, Anja and Beier, Rita and Sch{\"u}tte, Peter and Fedders, Birthe and Alten, Julia and Hinze, Laura and Klein, Norman and Kulozik, Andreas and Muckenthaler, Martina and K{\"o}hler, Rolf and Borkhardt, Arndt and Vijayakrishnan, Jayaram and Ellinghaus, David and Forster, Michael and Franke, Andre and Wintering, Astrid and Kratz, Christian P. and Schrappe, Martin and Schwab, Matthias and Houlston, Richard and Cario, Gunnar and Stanulla, Martin}, title={Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia}, subtitle={a genome-wide association study from the AIEOP-BFM ALL study group}, year={2023}, pages={1-15}, language={eng}, issn={1756-9966}, volume={42(2023) vom: Jan.}, number={Artikel-ID 21}, note={Gesehen am 22.03.2023}, journal={Journal of experimental & clinical cancer research}, doi={10.1186/s13046-022-02585-x}, } @article{UBHD-68503718, author={Kazman, Pamina and Vielberg, Marie-Theres and Pulido Cendales, María Daniela and Hunziger, Lioba and Weber, Benedikt and Hegenbart, Ute and Zacharias, Martin and K{\"o}hler, Rolf and Sch{\"o}nland, Stefan and Groll, Michael and Buchner, Johannes}, title={Fatal amyloid formation in a patient’s antibody light chain is caused by a single point mutation}, year={2020}, language={eng}, issn={2050-084X}, volume={9(2020) Artikel-Nummer e52300}, number={23 Seiten}, note={Gesehen am 11.03.2020}, journal={eLife}, doi={10.7554/eLife.52300}, } @article{UBHD-69054744, author={Kox, Corinne and Zimmermann, M. and Stanulla, M. and Leible, S. and Schrappe, M. and Ludwig, W.-D. and K{\"o}hler, Rolf and Tolle, G. and Bandapalli, Obul Reddy and Breit, S. and Muckenthaler, Martina and Kulozik, Andreas}, title={The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function}, year={2010}, pages={2005-2013}, language={eng}, issn={1476-5551}, volume={24}, number={12}, note={Gesehen am 22.03.2023}, journal={Leukemia}, doi={10.1038/leu.2010.203}, } @article{UBHD-68583325, author={Kunz, Joachim and Rausch, Tobias and Bandapalli, Obul Reddy and Eilers, Juliane and Richter-Pechańska, Paulina and Sch{\"u}ssele, Stephanie and Assenov, Yassen and St{\"u}tz, Adrian M. and Kirschner-Schwabe, Renate and Hof, Jana and Eckert, Cornelia and Stackelberg, Arend von and Schrappe, Martin and Stanulla, Martin and K{\"o}hler, Rolf and Avigad, Smadar and Elitzur, Sarah and Handgretinger, Rupert and Benes, Vladimir and Weischenfeldt, Joachim and Korbel, Jan Oliver and Muckenthaler, Martina and Kulozik, Andreas}, title={Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation}, year={2015}, pages={1442-1450}, language={eng}, issn={1592-8721}, volume={100}, number={11}, note={Gesehen am 03.06.2020}, journal={Haematologica}, doi={10.3324/haematol.2015.129692}, } @article{UBHD-67694937, author={Meißner, Barbara and Bartram, Claus R. and K{\"o}hler, Rolf}, title={Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia}, year={2014}, pages={590-601}, language={eng}, issn={1460-2083}, volume={23}, number={3}, note={Gesehen am 30.10.2014}, journal={Human molecular genetics}, doi={10.1093/hmg/ddt447}, } @article{UBHD-68740266, author={Migliorini, Gabriele and Fiege, Bettina and Hosking, Fay J. and Ma, Yussanne and Kumar, Rajiv and Sherborne, Amy L. and Silva Filho, Miguel Inacio da and Vijayakrishnan, Jayaram and K{\"o}hler, Rolf and Thomsen, Hauke and Irving, Julie A. and Allan, James M. and Lightfoot, Tracy and Roman, Eve and Kinsey, Sally E. and Sheridan, Eamonn and Thompson, Pamela and Hoffmann, Per and N{\"o}then, Markus M. and M{\"u}hleisen, Thomas W. and Eisele, Lewin and Zimmermann, Martin and Bartram, Claus R. and Schrappe, Martin and Greaves, Mel and Stanulla, Martin and Hemminki, Kari and Houlston, Richard S.}, title={Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype}, year={2013}, pages={3298-3307}, language={eng}, issn={1528-0020}, volume={122}, number={19}, note={Gesehen am 21.05.2021}, journal={Blood}, doi={10.1182/blood-2013-03-491316}, } @article{UBHD-68297438, author={M{\"u}nch, Vera and Trentin, Luca and Herzig, Julia Katharina and K{\"o}hler, Rolf}, title={Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor}, year={2017}, pages={643-654}, language={eng}, issn={1528-0020}, volume={130}, number={5}, note={Gesehen am 21.08.2018}, journal={Blood}, doi={10.1182/blood-2017-03-769315}, } @article{UBHD-68978755, author={Schrappe, Martin and Valsecchi, Maria Grazia and Bartram, Claus R. and Schrauder, André and Panzer-Gr{\"u}mayer, Renate and M{\"o}ricke, Anja and Parasole, Rosanna and Zimmermann, Martin and Dworzak, Michael and Buldini, Barbara and Reiter, Alfred and Basso, Giuseppe and Klingebiel, Thomas and Messina, Chiara and Ratei, Richard and Cazzaniga, Giovanni and K{\"o}hler, Rolf and Locatelli, Franco and Sch{\"a}fer, Beat W. and Aricò, Maurizio and Welte, Karl and van Dongen, Jacques J.M. and Gadner, Helmut and Biondi, Andrea and Conter, Valentino}, title={Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL}, subtitle={results of the AIEOP-BFM-ALL 2000 study}, year={2011}, pages={2077-2084}, language={eng}, issn={1528-0020}, volume={118}, number={8 vom: Aug.}, note={Gesehen am 26.10.2022}, journal={Blood}, doi={10.1182/blood-2011-03-338707}, } @article{UBHD-69095955, author={Sherborne, Amy and Hosking, Fay J. and Bokkasa, Rashmi Prasad and Kumar, Rajiv and K{\"o}hler, Rolf and Vijayakrishnan, Jayaram and Papaemmanuil, Elli and Bartram, Claus R. and Stanulla, Martin and Schrappe, Martin and Gast, Andreas and Dobbins, Sara E. and Ma, Yussanne and Sheridan, Eamonn and Taylor, Malcolm and Kinsey, Sally E. and Lightfoot, Tracey and Roman, Eve and Irving, Julie A. E. and Allan, James M. and Moorman, Anthony V. and Harrison, Christine J. and Tomlinson, Ian P. and Richards, Sue and Zimmermann, Martin and Szalai, Csaba and Semsei, Ágnes F. and Erdelyi, Daniel J. and Krajinovic, Maja and Sinnett, Daniel and Healy, Jasmine and Neira, Anna Gonzalez and Kawamata, Norihiko and Ogawa, Seishi and Koeffler, H. Phillip and Hemminki, Kari and Greaves, Melvyn F. and Houlston, Richard S.}, title={Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk}, year={2010}, pages={492-494}, language={eng}, issn={1546-1718}, volume={42}, number={6}, note={Gesehen am 12.07.2023}, journal={Nature genetics}, doi={10.1038/ng.585}, } @article{UBHD-68563102, author={Stanulla, Martin and Dagdan, Elif and Zaliova, Marketa and M{\"o}ricke, Anja and Palmi, Chiara and Cazzaniga, Giovanni and Eckert, Cornelia and te Kronnie, Geertruy and Bourquin, Jean-Pierre and Bornhauser, Beat and K{\"o}hler, Rolf and Bartram, Claus R. and Ludwig, Wolf-Dieter and Bleckmann, Kirsten and Groeneveld-Krentz, Stefanie and Schewe, Denis and Junk, Stefanie V. and Hinze, Laura and Klein, Norman and Kratz, Christian P. and Biondi, Andrea and Borkhardt, Arndt and Kulozik, Andreas and Muckenthaler, Martina and Basso, Giuseppe and Valsecchi, Maria Grazia and Izraeli, Shai and Petersen, Britt-Sabina and Franke, Andre and D{\"o}rge, Petra and Steinemann, Doris and Haas, Oskar A. and Panzer-Gr{\"u}mayer, Renate and Cavé, Hélène and Houlston, Richard S. and Cario, Gunnar and Schrappe, Martin and Zimmermann, Martin}, title={IKZF1plus defines a new minimal residual disease-dependent very-poor prognostic profile in pediatric B-cell precursor acute lymphoblastic leukemia}, year={2018}, pages={1240-1249}, language={eng}, issn={1527-7755}, volume={36}, number={12}, note={Gesehen am 08.04.2020 ; Im Titel ist "plus" in IKZF1plus hochgestellt}, journal={Journal of clinical oncology}, doi={10.1200/JCO.2017.74.3617}, } @article{UBHD-68366432, author={Vijayakrishnan, Jayaram and Rachakonda, P. Sivaramakrishna and K{\"o}hler, Rolf and Bartram, Claus R. and Hemminki, Kari and Kumar, Rajiv}, title={Author correction}, subtitle={genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia}, year={2019}, pages={3 S.}, language={eng}, issn={2041-1723}, volume={10(2019) Artikel-Nummer 419}, number={3 Seiten}, note={#Jayaram Vijayakrishnan, Sivaramakrishna Rachakonda, Rolf Koehler, Claus R. Bartram, Kari Hemminki [und weitere] ; Gesehen am 06.03.2019}, journal={Nature Communications}, doi={10.1038/s41467-018-08106-9}, } @article{UBHD-68305372, author={Vijayakrishnan, Jayaram and Kumar, Rajiv and Rachakonda, P. Sivaramakrishna and K{\"o}hler, Rolf and Thomsen, Hauke and Bartram, Claus R. and Hemminki, Kari}, title={A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1}, year={2017}, pages={573-579}, language={eng}, issn={1476-5551}, volume={31}, number={3}, note={Advance online publication, 11 November 2016 ; Gesehen am 17.09.2018}, journal={Leukemia}, doi={10.1038/leu.2016.271}, } @article{UBHD-68249963, author={Vijayakrishnan, Jayaram and Rachakonda, P. Sivaramakrishna and K{\"o}hler, Rolf and Bartram, Claus R. and Hemminki, Kari and Kumar, Rajiv and Brenner, Hermann}, title={Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia}, year={2018}, pages={9 S.}, language={eng}, issn={2041-1723}, volume={9(2018) Artikel-Nummer 1340}, number={9 Seiten}, note={Gesehen am 07.03.2019 ; Hermann Brenner is a member of the PRACTICAL consortium}, journal={Nature Communications}, doi={10.1038/s41467-018-03178-z}, } @article{UBHD-68594306, author={Wesołowska, Agata and Borst, L. and Dalgaard, M. D. and Yadav, R. and Rasmussen, K. K. and Wehner, P. S. and Rasmussen, M. and Ørntoft, T. F. and Nordentoft, I. and K{\"o}hler, Rolf and Bartram, Claus R. and Schrappe, M. and Sicheritz-Ponten, T. and Gautier, L. and Marquart, H. and Madsen, H. O. and Brunak, S. and Stanulla, M. and Gupta, R. and Schmiegelow, K.}, title={Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients}, year={2015}, pages={297-303}, language={eng}, issn={1476-5551}, volume={29}, number={2}, note={advance online publication, 25 July 2014 ; Gesehen am 30.06.2020}, journal={Leukemia}, doi={10.1038/leu.2014.205}, } @article{UBHD-67580842, author={Zaliova, Mau and K{\"o}hler, Rolf and Bartram, Claus R.}, title={ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia}, year={2014}, pages={182-185}, language={eng}, issn={1476-5551}, volume={28}, number={1}, journal={Leukemia}, doi={10.1038/leu.2013.282}, } @article{UBHD-68323182, author={Zeidler, Lutz and K{\"o}hler, Rolf and Bartram, Claus R.}, title={Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome}, year={2012}, pages={402-409}, language={eng}, issn={1592-8721}, volume={97}, number={3}, note={Gesehen am 30.10.2018}, journal={Haematologica, the hematology journal}, doi={10.3324/haematol.2011.045229}, } @article{UBHD-68420587, author={Zuna, Jan and K{\"o}hler, Rolf}, title={Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia}, year={2016}, pages={742-748}, language={eng}, issn={1365-2141}, volume={173}, number={5}, note={Gesehen am 14.08.2019}, journal={British journal of haematology}, doi={10.1111/bjh.13989}, }