@article{UBHD-67436521, author={Abel, Ulrich and Deichmann, Annette and Nowrouzi, Ali and Gabriel, Richard and Bartholom{\"a}, Cynthia C. and Glimm, Hanno and Kalle, Christof von and Schmidt, Manfred}, title={Analyzing the number of common integration sites of viral vectors}, subtitle={new methods and computer programs}, year={2011}, pages={8 S.}, language={eng}, issn={1932-6203}, volume={6(2011}, note={Gesehen am 26.06.2013}, journal={PLOS ONE}, doi={10.1371/journal.pone.0024247}, } @article{UBHD-68301963, author={Afzal, Saira and Wilkening, Stefan and Kalle, Christof von and Schmidt, Manfred and Fronza, Raffaele}, title={GENE-IS}, subtitle={time-efficient and accurate analysis of viral integration events in large-scale gene therapy data}, year={2017}, pages={133-139}, language={eng}, issn={2162-2531}, volume={6}, note={Published online: 1 December 2016 ; Gesehen am 04.09.2018}, journal={Molecular therapy}, doi={10.1016/j.omtn.2016.12.001}, } @article{UBHD-68303081, author={Afzal, Saira and Gil-Fariña, Irene and Gabriel, Richard and Kalle, Christof von and Schmidt, Manfred and Fronza, Raffaele}, title={Systematic comparative study of computational methods for T-cell receptor sequencing data analysis}, year={2019}, pages={222-234}, language={eng}, issn={1477-4054}, volume={20}, number={1}, note={ Published: 23 September 2017 ; Gesehen am 08.07.2019}, journal={Briefings in bioinformatics}, doi={10.1093/bib/bbx111}, } @article{UBHD-68081318, author={Alaee, Farhang and Bartholom{\"a}, Cynthia C. and Schmidt, Manfred}, title={Biodistribution of LV-TSTA transduced rat bone marrow cells used for “ex-vivo” regional gene therapy for bone repair}, year={2015}, pages={481-491}, language={eng}, issn={1875-5631}, volume={15}, number={5}, note={Gesehen am 07.02.2017}, journal={Current gene therapy}, doi={10.2174/1566523215666150812120229}, } @article{UBHD-68302821, author={Ball, Claudia R. and Oppel, Felix and Ehrenberg, Karl Roland and Dubash, Taronish Dorab and Dieter, Sebastian M. and Hoffmann, Christopher M. and Abel, Ulrich and Herbst, Friederike and Koch, Moritz and Werner, Jens and Bergmann, Frank and Schmidt, Manfred and Kalle, Christof von and Scholl, Claudia and Fr{\"o}hling, Stefan and Brors, Benedikt and Weichert, Wilko and Weitz, J{\"u}rgen and Glimm, Hanno}, title={Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts}, year={2017}, pages={918-932}, language={eng}, issn={1757-4684}, volume={9}, number={7}, note={Gesehen am 06.09.2018}, journal={EMBO molecular medicine}, doi={10.15252/emmm.201607354}, } @article{UBHD-67994479, author={Bartholom{\"a}, Cynthia C. and Kutschera, Ina and Kalle, Christof von and Schmidt, Manfred}, title={Integration-deficient lentiviral vectors expressing codon-optimized R338L human FIX restore normal hemostasis in hemophilia B mice}, year={2014}, pages={567-574}, language={eng}, issn={1525-0024}, volume={22}, number={3}, note={Gesehen am 10.06.2016}, journal={Molecular therapy}, doi={10.1038/mt.2013.188}, } @article{UBHD-67436524, author={Bartholom{\"a}, Cynthia C. and Arens, Anne and Balaggan, Kamaljit S. and Yáñez-Muñoz, Rafael J. and Montini, Eugenio and Howe, Steven J. and Paruzynski, Anna and Korn, Bernhard and Appelt, Jens-Uwe and MacNeil, Angus and Cesana, Daniela and Abel, Ulrich and Glimm, Hanno and Naldini, Luigi and Ali, Robin R. and Thrasher, Adrian J. and Kalle, Christof von and Schmidt, Manfred}, title={Lentiviral vector integration profiles differ in rodent postmitotic tissues}, year={2011}, pages={703-710}, language={eng}, issn={1525-0016}, volume={19}, number={4}, journal={Molecular therapy}, } @article{UBHD-68879816, author={Bartholom{\"a}, Cynthia C. and Arens, Anne and Balaggan, Kamaljit S. and Yáñez-Muñoz, Rafael J. and Montini, Eugenio and Howe, Steven J. and Paruzynski, Anna and Korn, Bernhard and Appelt, Jens-Uwe and MacNeil, Angus and Cesana, Daniela and Abel, Ulrich and Glimm, Hanno and Naldini, Luigi and Ali, Robin R. and Thrasher, Adrian J. and Kalle, Christof von and Schmidt, Manfred}, title={Lentiviral vector integration profiles differ in rodent postmitotic tissues}, year={2011}, pages={703-710}, language={eng}, issn={1525-0024}, volume={19}, number={4 vom: Apr.}, note={First published online: 14 December 2016 ; Gesehen am 17.02.2022}, journal={Molecular therapy}, doi={10.1038/mt.2011.19}, } @article{UBHD-68120867, author={Bergot, Anne-Sophie and Ruggiero, Eliana and Schmidt, Manfred and Kalle, Christof von}, title={TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice}, year={2015}, pages={1524-1534}, language={eng}, issn={1521-4141}, volume={45}, number={5}, note={Gesehen am 18.05.2017}, journal={European journal of immunology}, doi={10.1002/eji.201445269}, } @article{UBHD-68898712, author={Biasco, Luca and Ambrosi, Alessandro and Pellin, Danilo and Bartholom{\"a}, Cynthia C. and Brigida, Immacolata and Roncarolo, Maria Grazia and Di Serio, Clelia and Kalle, Christof von and Schmidt, Manfred and Aiuti, Alessandro}, title={Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell}, year={2011}, pages={89-101}, language={eng}, issn={1757-4684}, volume={3}, number={2}, note={Gesehen am 23.03.2022}, journal={EMBO molecular medicine}, doi={10.1002/emmm.201000108}, } @article{UBHD-68898768, author={Biffi, Alessandra and Bartholom{\"a}, Cynthia C. and Cesana, Daniela and Cartier, Natalie and Aubourg, Patrik and Ranzani, Marco and Cesani, Martina and Benedicenti, Fabrizio and Plati, Tiziana and Rubagotti, Enrico and Merella, Stefania and Capotondo, Alessia and Sgualdino, Jacopo and Zanetti, Gianluigi and Kalle, Christof von and Schmidt, Manfred and Naldini, Luigi and Montini, Eugenio}, title={Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection}, year={2011}, pages={5332-5339}, language={eng}, issn={1528-0020}, volume={117}, number={20}, note={Gesehen am 23.03.2022}, journal={Blood}, doi={10.1182/blood-2010-09-306761}, } @article{UBHD-69042258, author={Boztug, Kaan and Schmidt, Manfred and Schwarzer, Adrian and Banerjee, Pinaki P. and Díez, Inés Avedillo and Dewey, Ricardo A. and B{\"o}hm, Marie and Nowrouzi, Ali and Ball, Claudia R. and Glimm, Hanno and Naundorf, Sonja and K{\"u}hlcke, Klaus and Blasczyk, Rainer and Kondratenko, Irina and Maródi, László and Orange, Jordan S. and Kalle, Christof von and Klein, Christoph}, title={Stem-cell gene therapy for the Wiskott-Aldrich Syndrome}, year={2010}, pages={1918-1927}, language={eng}, issn={1533-4406}, volume={363}, number={20}, note={Gesehen am 15.02.2023}, journal={The New England journal of medicine}, doi={10.1056/NEJMoa1003548}, } @article{UBHD-68028128, author={B{\"u}ning, Hildegard and Schmidt, Manfred}, title={Adeno-associated vector toxicity}, subtitle={to be or not to be?}, year={2015}, pages={1673-1675}, language={eng}, issn={1525-0024}, volume={23}, number={11}, note={Gesehen am 13.09.2016}, journal={Molecular therapy}, doi={10.1038/mt.2015.182}, } @article{UBHD-68167907, author={Cantore, Alessio and Bartholom{\"a}, Cynthia C. and Schmidt, Manfred}, title={Liver-directed lentiviral gene therapy in a dog model of hemophilia B}, year={2015}, pages={12 S.}, language={eng}, issn={1946-6242}, volume={7(2015}, note={Gesehen am 20.09.2017}, journal={Science translational medicine}, doi={10.1126/scitranslmed.aaa1405}, } @article{UBHD-69010630, author={Cattoglio, Claudia and Maruggi, Giulietta and Bartholom{\"a}, Cynthia C. and Malani, Nirav and Pellin, Danilo and Cocchiarella, Fabienne and Magnani, Zulma and Ciceri, Fabio and Ambrosi, Alessandro and Kalle, Christof von and Bushman, Frederic D. and Bonini, Chiara and Schmidt, Manfred and Mavilio, Fulvio and Recchia, Alessandra}, title={High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion}, year={2010}, pages={1-14}, language={eng}, issn={1932-6203}, volume={5}, note={Gesehen am 26.01.2023}, journal={PLOS ONE}, doi={10.1371/journal.pone.0015688}, } @article{UBHD-67837659, author={Cavazzana, Marina and Schmidt, Manfred and Kalle, Christof von}, title={Study Hgb-205}, subtitle={outcomes of gene therapy for hemoglobinopathies via transplantation of autologous hematopoietic stem cells Transduced ex vivo with a lentiviral beta(A-T87Q)-globin vector (LentiGlobin (R) BB305 drug product)}, year={2014}, pages={1 S.}, language={eng}, issn={1528-0020}, volume={124(2014}, note={Gesehen am 30.06.2015}, journal={Blood}, } @article{UBHD-67924038, author={Cesana, Daniela and Bartholom{\"a}, Cynthia C. and Kalle, Christof von and Schmidt, Manfred}, title={Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo}, year={2014}, pages={774-785}, language={eng}, issn={1525-0024}, volume={22}, number={4}, note={Gesehen am 12.01.2016}, journal={Molecular therapy}, doi={10.1038/mt.2014.3}, } @article{UBHD-68378047, author={Chan, Jerry K. Y. and Gil-Fariña, Irene and Schmidt, Manfred}, title={Therapeutic expression of human clotting factors IX and X following adeno-associated viral vector-mediated intrauterine gene transfer in early-gestation fetal macaques}, year={2019}, pages={3954-3967}, language={eng}, issn={1530-6860}, volume={33}, number={3}, note={Gesehen am 01.04.2019}, journal={The FASEB journal}, doi={10.1096/fj.201801391R}, } @article{UBHD-68670403, author={Darche, Fabrice Fernand and Rivinius, Rasmus and K{\"o}llensperger, Eva and Leimer, Uwe and Germann, G{\"u}nter and Seckinger, Anja and Hose, Dirk and Schr{\"o}ter, Julian and Bruehl, Claus and Draguhn, Andreas and Gabriel, Richard and Schmidt, Manfred and Koenen, Michael and Thomas, Dierk and Katus, Hugo and Schweizer, Patrick Alexander}, title={Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells}, year={2019}, pages={1-16}, language={eng}, issn={1879-0631}, volume={232}, number={Artikel-ID 116620}, note={Gesehen am 08.12.2020}, journal={Life sciences}, doi={10.1016/j.lfs.2019.116620}, } @article{UBHD-68199262, author={D'Avola, Delia and Gil-Fariña, Irene and Schmidt, Manfred}, title={Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria}, year={2016}, pages={776-783}, language={eng}, issn={1600-0641}, volume={65}, number={4}, note={Gesehen am 07.12.2017}, journal={Journal of hepatology}, doi={10.1016/j.jhep.2016.05.012}, } @article{UBHD-68913891, author={Deichmann, Annette and Brugman, Martijn H and Bartholom{\"a}, Cynthia C. and Schwarzwaelder, Kerstin and Verstegen, Monique MA and Howe, Steven J and Arens, Anne and Ott, Marion G and Hoelzer, Dieter and Seger, Reinhard and Grez, Manuel and Hacein-Bey-Abina, Salima and Cavazzana-Calvo, Marina and Fischer, Alain and Paruzynski, Anna and Gabriel, Richard and Glimm, Hanno and Abel, Ulrich and Cattoglio, Claudia and Mavilio, Fulvio and Cassani, Barbara and Aiuti, Alessandro and Dunbar, Cynthia E and Baum, Christopher and Gaspar, H Bobby and Thrasher, Adrian J and Kalle, Christof von and Schmidt, Manfred and Wagemaker, Gerard}, title={Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after ´gammaretroviral vector gene therapy}, year={2011}, pages={2031-2039}, language={eng}, issn={1525-0024}, volume={19}, number={11}, note={Gesehen am 03.05.2022}, journal={Molecular therapy}, doi={10.1038/mt.2011.178}, } @article{UBHD-68929706, author={Dieter, Sebastian M. and Ball, Claudia R. and Hoffmann, Christopher M. and Nowrouzi, Ali and Herbst, Friederike and Zavidij, Oksana and Abel, Ulrich and Arens, Anne and Weichert, Wilko and Brand, Karsten and Koch, Moritz and Weitz, J{\"u}rgen and Schmidt, Manfred and Kalle, Christof von and Glimm, Hanno}, title={Distinct types of tumor-initiating cells form human colon cancer tumors and metastases}, year={2011}, pages={357-365}, language={eng}, issn={1875-9777}, volume={9}, number={4}, note={Gesehen am 10.06.2022}, journal={Cell stem cell}, doi={10.1016/j.stem.2011.08.010}, } @article{UBHD-68302355, author={Dieter, Sebastian M. and Gießler, Klara Monika and Kriegsmann, Mark and Dubash, Taronish Dorab and Siegl, Christine and Weber, Sarah and Heger, Ulrike and Gao, Jianpeng and Hartinger, Eva-Maria and Oppel, Felix and Hoffmann, Christopher M. and Ha, Nati and Brors, Benedikt and Lasitschka, Felix and Ulrich, Alexis and Strobel, Oliver and Schmidt, Manfred and Kalle, Christof von and Schneider, Martin and Weichert, Wilko and Glimm, Hanno and Ball, Claudia R.}, title={Patient-derived xenografts of gastrointestinal cancers are susceptible to rapid and delayed B-lymphoproliferation}, year={2017}, pages={1356-1363}, language={eng}, issn={1097-0215}, volume={140}, number={6}, note={First published: 09 December 2016 ; Gesehen am 05.09.2018}, journal={International journal of cancer}, doi={10.1002/ijc.30561}, } @article{UBHD-68571143, author={Dubash, Taronish Dorab and Hoffmann, Christopher M. and Oppel, Felix and Gießler, Klara Monika and Weber, Sarah and Dieter, Sebastian M. and H{\"u}llein, Jennifer and Zenz, Thorsten and Herbst, Friederike and Scholl, Claudia and Weichert, Wilko and Werft, Wiebke and Benner, Axel and Schmidt, Manfred and Schneider, Martin and Glimm, Hanno and Ball, Claudia R.}, title={Phenotypic differentiation does not affect tumorigenicity of primary human colon cancer initiating cells}, year={2016}, pages={326-333}, language={eng}, issn={1872-7980}, volume={371}, number={2}, note={Available online 8 December 2015 ; Gesehen am 28.04.2020}, journal={Cancer letters}, doi={10.1016/j.canlet.2015.11.037}, } @article{UBHD-68581688, author={Fronza, Raffaele and Vasciaveo, Alessandro and Benso, Alfredo and Schmidt, Manfred}, title={A graph based framework to model virus integration sites}, year={2016}, pages={69-77}, language={eng}, issn={2001-0370}, volume={14}, note={Available online 30 November 2015 ; Gesehen am 28.05.2020}, journal={Computational and structural biotechnology journal}, doi={10.1016/j.csbj.2015.10.006}, } @article{UBHD-67977734, author={Gabriel, Richard and Kutschera, Ina and Bartholom{\"a}, Cynthia C. and Kalle, Christof von and Schmidt, Manfred}, title={Linear amplification mediated PCR}, subtitle={localization of genetic elements and characterization of unknown flanking DNA}, year={2014}, pages={1 Online-Ressource (1 Videodatei, 11:57 min)}, language={eng}, issn={1940-087X}, volume={(2014}, note={Enth{\"a}lt auch Textversion ; Gesehen am 12.05.2016 ; Wissenschaftlicher Film. Deutschland. 2014}, journal={JoVE}, doi={10.3791/51543}, } @article{UBHD-68128583, author={Gabriel, Richard and Kalle, Christof von and Schmidt, Manfred}, title={Mapping the precision of genome editing}, year={2015}, pages={150-152}, language={eng}, issn={1546-1696}, volume={33}, number={2}, note={Gesehen am 14.06.2017}, journal={Nature biotechnology}, doi={10.1038/nbt.3142}, } @article{UBHD-69093647, author={Gabriel, Richard and Lombardo, Angelo and Arens, Anne and Miller, Jeffrey C. and Genovese, Pietro and K{\"a}ppel, Christine and Nowrouzi, Ali and Bartholom{\"a}, Cynthia C. and Wang, Jianbin and Friedman, Geoffrey and Holmes, Michael C. and Gregory, Philip D. and Glimm, Hanno and Schmidt, Manfred and Naldini, Luigi and Kalle, Christof von}, title={An unbiased genome-wide analysis of zinc-finger nuclease specificity}, year={2011}, pages={816-823}, language={eng}, issn={1546-1696}, volume={29}, number={9 vom: Sept.}, note={Gesehen am 05.07.2023}, journal={Nature biotechnology}, doi={10.1038/nbt.1948}, } @article{UBHD-69142573, author={Gama-Norton, Leonor and Herrmann, S. and Schucht, R. and Coroadinha, A. S. and L{\"o}w, R. and Alves, P. M. and Bartholom{\"a}, Cynthia C. and Schmidt, Manfred and Baum, C. and Schambach, A. and Hauser, H. and Wirth, D.}, title={Retroviral vector performance in defined chromosomal loci of modular packaging cell lines}, year={2010}, pages={979-991}, language={eng}, issn={1557-7422}, volume={21}, number={8 vom: Aug.}, note={Gesehen am 14.11.2023}, journal={Human gene therapy}, doi={10.1089/hum.2009.089}, } @article{UBHD-68140742, author={Gardyan, Adriane and Z{\"o}rnig, Inka and Aulmann, Sebastian and Ruggiero, Eliana and Schmidt, Manfred and Halama, Niels and Kalle, Christof von and Schneeweiss, Andreas and J{\"a}ger, Dirk and Eichm{\"u}ller, Stefan B.}, title={Identification of NY-BR-1-specific CD4+ T cell epitopes using HLA-transgenic mice}, year={2015}, pages={2588-2597}, language={eng}, issn={2167-9118}, volume={136}, number={11}, note={Gesehen am 20.07.2017}, journal={International journal of Cancer Studies & Research}, doi={10.1002/ijc.29322}, } @article{UBHD-68263864, author={Gießler, Klara Monika and Kleinheinz, Kortine and H{\"u}bschmann, Daniel and Balasubramanian, Gnana Prakash and Dubash, Taronish Dorab and Dieter, Sebastian M. and Siegl, Christine and Herbst, Friederike and Weber, Sarah and Hoffmann, Christopher M. and Fronza, Raffaele and Buchhalter, Ivo and Paramasivam, Nagarajan and Eils, Roland and Schmidt, Manfred and Kalle, Christof von and Schneider, Martin and Ulrich, Alexis and Scholl, Claudia and Fr{\"o}hling, Stefan and Weichert, Wilko and Brors, Benedikt and Schlesner, Matthias and Ball, Claudia R. and Glimm, Hanno}, title={Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer}, year={2017}, pages={2073-2088}, language={eng}, issn={1540-9538}, volume={214}, number={7}, note={Published June 1, 2017 ; Gesehen am 20.06.2018}, journal={Journal of experimental medicine}, doi={10.1084/jem.20162017}, } @article{UBHD-68176401, author={Gil-Fariña, Irene and Schmidt, Manfred}, title={Interaction of vectors and parental viruses with the host genome}, year={2016}, pages={35-40}, language={eng}, issn={1879-6265}, volume={21}, number={Supplement C}, note={Gesehen am 06.10.2017}, journal={Current opinion in virology}, doi={10.1016/j.coviro.2016.07.004}, } @article{UBHD-68374240, author={Gil-Fariña, Irene and Fronza, Raffaele and Schmidt, Manfred}, title={Recombinant AAV integration is not associated with hepatic genotoxicity in nonhuman primates and patients}, year={2016}, pages={1100-1105}, language={eng}, issn={1525-0024}, volume={24}, number={6}, note={Gesehen am 29.03.2019}, journal={Molecular therapy}, doi={10.1038/mt.2016.52}, } @article{UBHD-68768838, author={Giordano, Frank Anton and Appelt, Jens-Uwe and Link, Barbara and Gerdes, Sebastian and Scholz, Simone and Paruzynski, Anna and R{\"o}der, Ingo and Wenz, Frederik and Glimm, Hanno and Kalle, Christof von and Grez, Manuel and Schmidt, Manfred and Maier-Laufs, Stephanie}, title={High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies}, year={2015}, pages={1-8}, language={eng}, issn={2329-0501}, volume={2}, number={Artikel-ID 14061}, note={Elektronische Reproduktion der Druckausgabe ; Gesehen am 11.08.2021}, journal={Molecular therapy}, doi={10.1038/mtm.2014.61}, } @article{UBHD-68238458, author={Gonzaléz-Prieto, Coral and Gabriel, Richard and Schmidt, Manfred}, title={The conjugative relaxase TrwC promotes integration of foreign DNA in the human genome}, year={2017}, pages={16 S.}, language={eng}, issn={1098-5336}, volume={83(2017}, note={Gesehen am 03.04.2018}, journal={Applied and environmental microbiology}, doi={10.1128/AEM.00207-17}, } @article{UBHD-68884471, author={Hanna, Bola and Llaó Cid, Laura and ̇Iskar, Murat and R{\"o}ßner, Philipp M. and Klett, Lara C. and Wong, John K. L. and Paul, Yashna and Ioannou, Nikolaos and {\"O}zt{\"u}rk, Selcen and Mack, Norman and Kalter, Verena and Colomer, Dolors and Campo, Elías and Bloehdorn, Johannes and Stilgenbauer, Stephan and Dietrich, Sascha and Schmidt, Manfred and Gabriel, Richard and Rippe, Karsten and Feuerer, Markus and Ramsay, Alan G. and Lichter, Peter and Zapatka, Marc and Seiffert, Martina}, title={Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity}, year={2021}, pages={2825-2841}, language={eng}, issn={1097-4180}, volume={54}, number={12}, note={Gesehen am 02.03.2022 ; Im Titel sind "int" und "+" hochgestellt}, journal={Immunity}, doi={10.1016/j.immuni.2021.11.004}, } @article{UBHD-68405369, author={Hanna, Bola S. and Schmidt, Manfred and Gabriel, Richard and Lichter, Peter and Seiffert, Martina}, title={Control of chronic lymphocytic leukemia development by clonally-expanded CD8 + T-cells that undergo functional exhaustion in secondary lymphoid tissues}, year={2019}, pages={625-637}, language={eng}, issn={1476-5551}, volume={33}, number={3}, note={Published: 28 September 2018 ; Gesehen am 05.07.2019}, journal={Leukemia}, doi={10.1038/s41375-018-0250-6}, } @article{UBHD-68971042, author={Herbst, Friederike and Ball, Claudia R. and Zavidij, Oksana and Fessler, Sylvia and Schmidt, Manfred and Veelken, Hendrik and Kalle, Christof von and Glimm, Hanno}, title={10-year stability of clinical-grade serum-free γ-retroviral vector-containing medium}, year={2011}, pages={210-212}, language={eng}, issn={1476-5462}, volume={18}, number={2}, note={Published: 11 November 2010 ; Gesehen am 06.10.2022}, journal={Gene therapy}, doi={10.1038/gt.2010.126}, } @article{UBHD-68744618, author={Herbst, Friederike and Lang, Tonio and Eckert, Elias S. P. and W{\"u}nsche, Peer and Wurm, Alexander A. and Kindinger, Tim and Laaber, Karin and Hemmati, Shayda and Hotz-Wagenblatt, Agnes and Zavidij, Oksana and Paruzynski, Anna and Lu, Junyan and Kalle, Christof von and Zenz, Thorsten and Klein, Christoph and Schmidt, Manfred and Ball, Claudia R. and Glimm, Hanno}, title={The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision}, year={2021}, pages={2948-2963}, language={eng}, issn={1476-5551}, volume={35}, number={10}, note={Gesehen am 07.10.2021}, journal={Leukemia}, doi={10.1038/s41375-021-01267-5}, } @article{UBHD-68801832, author={H{\"u}llein, Jennifer and Jethwa, Alexander and Stolz, Tatjana and Blume, Carolin and Sellner, Leopold and Sill, Martin and Langer, Christian and Jauch, Anna and Paruzynski, Anna and Kalle, Christof von and Schmidt, Manfred and Glimm, Hanno and Zenz, Thorsten}, title={Next-generation sequencing of cancer consensus genes in lymphoma}, year={2013}, pages={1831-1835}, language={eng}, issn={1029-2403}, volume={54}, number={8}, note={Gesehen am 16.11.2021}, journal={Leukemia and lymphoma}, doi={10.3109/10428194.2013.796053}, } @article{UBHD-68936600, author={Huston, Marshall W. and van Til, Niek P and Visser, Trudi P and Arshad, Shazia and Brugman, Martijn H and Cattoglio, Claudia and Nowrouzi, Ali and Li, Yuedan and Schambach, Axel and Schmidt, Manfred and Baum, Christopher and Kalle, Christof von and Mavilio, Fulvio and Zhang, Fang and Blundell, Mike P and Thrasher, Adrian J and Verstegen, Monique MA and Wagemaker, Gerard}, title={Correction of murine SCID-X1 by lentiviral gene therapy using a codon-optimized IL2RG gene and minimal pretransplant conditioning}, year={2011}, pages={1867-1877}, language={eng}, issn={1525-0024}, volume={19}, number={10}, note={Elektronische Reproduktion der Druckausgabe ; Gesehen am 01.07.2022}, journal={Molecular therapy}, doi={10.1038/mt.2011.127}, } @article{UBHD-68573696, author={Jones, David T. W. and J{\"a}ger, Natalie and Kool, Marcel and Zichner, Thomas and Hutter, Barbara and Sultan, Marc and Cho, Yoon-Jae and Pugh, Trevor and Hovestadt, Volker and St{\"u}tz, Adrian M. and Rausch, Tobias and Warnatz, Hans-J{\"o}rg and Ryzhova, Marina and Bender, Sebastian and Sturm, Dominik and Pleier, Sabrina Valesca and Şeker-Cin, Huriye and Pfaff, Elke and Sieber, Laura and Wittmann, Andrea and Remke, Marc and Witt, Hendrik and Hutter, Sonja and Tzaridis, Theophilos-Dimitrios and Weischenfeldt, Joachim and Raeder, Benjamin and Avci, Meryem and Amstislavskiy, Vyacheslav and Zapatka, Marc and Weber, Ursula D. and Wang, Qi and Lasitschka, B{\"a}rbel and Bartholom{\"a}, Cynthia C. and Schmidt, Manfred and Kalle, Christof von and Ast, Volker and Lawerenz, Christian and Eils, J{\"u}rgen and Kabbe, Rolf and Benes, Vladimir and Sluis, Peter van and Koster, Jan and Volckmann, Richard and Shih, David and Betts, Matthew J. and Russell, Robert B. and Coco, Simona and Paolo Tonini, Gian and Sch{\"u}ller, Ulrich and Hans, Volkmar and Graf, Norbert and Kim, Yoo-Jin and Monoranu, Camelia and Roggendorf, Wolfgang and Unterberg, Andreas and Herold-Mende, Christel and Milde, Till and Kulozik, Andreas and Deimling, Andreas von and Witt, Olaf and Maass, Eberhard and R{\"o}ssler, Jochen and Ebinger, Martin and Schuhmann, Martin U. and Fr{\"u}hwald, Michael and Hasselblatt, Martin and Jabado, Nada and Rutkowski, Stefan and Bueren, André von and Williamson, Dan and Clifford, Steven C. and McCabe, Martin G. and Peter Collins, V. and Wolf, Stephan and Wiemann, Stefan and Lehrach, Hans and Brors, Benedikt and Scheurlen, Wolfram and Felsberg, J{\"o}rg and Reifenberger, Guido and Northcott, Paul A. and Taylor, Michael D. and Meyerson, Matthew and Pomeroy, Scott L. and Yaspo, Marie-Laure and Korbel, Jan Oliver and Korshunov, Andrey and Eils, Roland and Pfister, Stefan and Lichter, Peter}, title={Dissecting the genomic complexity underlying medulloblastoma}, year={2012}, pages={100-105}, language={eng}, issn={0028-0836}, volume={488}, number={7409 vom: 20. Juni}, journal={Nature}, } @article{UBHD-68296998, author={Jones, David T. W. and J{\"a}ger, Natalie and Kool, Marcel and Zichner, Thomas and Hutter, Barbara and Sultan, Marc and Cho, Yoon-Jae and Pugh, Trevor and Hovestadt, Volker and St{\"u}tz, Adrian M. and Rausch, Tobias and Warnatz, Hans-J{\"o}rg and Ryzhova, Marina and Bender, Sebastian and Sturm, Dominik and Pleier, Sabrina Valesca and Şeker-Cin, Huriye and Pfaff, Elke and Sieber, Laura and Wittmann, Andrea and Remke, Marc and Witt, Hendrik and Hutter, Sonja and Tzaridis, Theophilos-Dimitrios and Weischenfeldt, Joachim and Zapatka, Marc and Bartholom{\"a}, Cynthia C. and Schmidt, Manfred and Kalle, Christof von and Ast, Volker and Lawerenz, Christian and Eils, J{\"u}rgen and Betts, Matthew J. and Russell, Robert B. and Roggendorf, Wolfgang and Unterberg, Andreas and Herold-Mende, Christel and Milde, Till and Kulozik, Andreas and Deimling, Andreas von and Witt, Olaf and Rutkowski, Stefan and Bueren, André von and Brors, Benedikt and Korbel, Jan Oliver and Korshunov, Andrey and Eils, Roland and Pfister, Stefan and Lichter, Peter}, title={Dissecting the genomic complexity underlying medulloblastoma}, year={2012}, pages={100-105}, language={eng}, issn={1476-4687}, volume={488}, number={7409}, note={Gesehen am 20.08.2018}, journal={Nature}, doi={10.1038/nature11284}, } @article{UBHD-68012456, author={K{\"a}ppel, Christine and Fronza, Raffaele and Wolf, Stephan and Nowrouzi, Ali and Glimm, Hanno and Kalle, Christof von and Schmidt, Manfred}, title={Reply to: NGS library preparation may generate artifactual integration sites of AAV vectors}, year={2014}, pages={578-579$t2}, language={eng}, issn={1546-170X}, volume={20}, number={6}, note={Gesehen am 29.07.2016}, journal={Nature medicine}, doi={10.1038/nm.3584}, } @article{UBHD-67984710, author={Kalle, Christof von and Deichmann, Annette and Schmidt, Manfred}, title={Vector integration and tumorigenesis}, year={2014}, pages={475-481}, language={eng}, issn={1557-7422}, volume={25}, number={6}, note={Gesehen am 17.05.2016}, journal={Human gene therapy}, doi={10.1089/hum.2014.2525}, } @article{UBHD-69046258, author={Kane, Nicole M. and Nowrouzi, Ali and Mukherjee, Sayandip and Blundell, Michael P and Greig, Jenny A and Lee, Wai Kwong and Houslay, Miles D and Milligan, Graeme and Mountford, Joanne C and Kalle, Christof von and Schmidt, Manfred and Thrasher, Adrian J and Baker, Andrew H}, title={Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors}, year={2010}, pages={2139-2145}, language={eng}, issn={1525-0024}, volume={18}, number={12}, note={Gesehen am 01.03.2023}, journal={Molecular therapy}, doi={10.1038/mt.2010.231}, } @article{UBHD-68939889, author={Kang, Hyoung Jin and Bartholom{\"a}, Cynthia C. and Paruzynski, Anna and Arens, Anne and Kim, Sujeong and Yu, Seung Shin and Hong, Youngtae and Joo, Chang-Wan and Yoon, Nam-Kyung and Rhim, Jung-Woo and Kim, Joong Gon and Kalle, Christof von and Schmidt, Manfred and Kim, Sunyoung and Ahn, Hyo Seop}, title={Retroviral gene therapy for X-linked chronic granulomatous disease}, subtitle={results from phase I/II trial}, year={2011}, pages={2092-2101}, language={eng}, issn={1525-0024}, volume={19}, number={11}, note={Gesehen am 11.07.2022}, journal={Molecular therapy}, doi={10.1038/mt.2011.166}, } @article{UBHD-68301972, author={Knipping, Friederike and Petri, Karl and Glimm, Hanno and Kalle, Christof von and Schmidt, Manfred and Gabriel, Richard}, title={Genome-wide specificity of highly efficient TALENs and CRISPR/Cas9 for T cell receptor modification}, year={2017}, pages={213-224}, language={eng}, issn={2329-0501}, volume={4}, note={Available online 12 February 2017 ; Gesehen am 04.09.2018}, journal={Molecular therapy}, doi={10.1016/j.omtm.2017.01.005}, } @article{UBHD-68789651, author={Kohn, Donald B. and Booth, Claire and Shaw, Kit L. and Xu-Bayford, Jinhua and Garabedian, Elizabeth and Trevisan, Valentina and Carbonaro-Sarracino, Denise A. and Soni, Kajal and Terrazas, Dayna and Snell, Katie and Ikeda, Alan and Leon-Rico, Diego and Moore, Theodore B. and Buckland, Karen F. and Shah, Ami J. and Gilmour, Kimberly C. and Oliveira, Satiro De and Rivat, Christine and Crooks, Gay M. and Izotova, Natalia and Tse, John and Adams, Stuart and Shupien, Sally and Ricketts, Hilory and Davila, Alejandra and Uzowuru, Chilenwa and Icreverzi, Amalia and Barman, Provaboti and Fernandez, Beatriz Campo and Hollis, Roger P. and Coronel, Maritess and Yu, Allen and Chun, Krista M. and Casas, Christian E. and Zhang, Ruixue and Arduini, Serena and Lynn, Frances and Kudari, Mahesh and Spezzi, Andrea and Zahn, Marco and Heimke, Rene and Labik, Ivan and Parrott, Roberta and Buckley, Rebecca H. and Reeves, Lilith and Cornetta, Kenneth and Sokolic, Robert and Hershfield, Michael and Schmidt, Manfred and Candotti, Fabio and Malech, Harry L. and Thrasher, Adrian J. and Gaspar, H. Bobby}, title={Autologous ex vivo lentiviral gene therapy for adenosine deaminase deficiency}, year={2021}, pages={2002-2013}, language={eng}, issn={1533-4406}, volume={384}, number={21 vom: Mai}, note={Gesehen am 13.10.2021}, journal={The New England journal of medicine}, doi={10.1056/NEJMoa2027675}, } @article{UBHD-68435916, author={Lucic, Bojana and Wei, Wang and Schmidt, Manfred and Lusic, Marina}, title={Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration}, year={2019}, pages={12 S.}, language={eng}, issn={2041-1723}, volume={10(2019) Artikel-Nummer 4059}, number={12 Seiten}, note={Gesehen am 07.10.2019}, journal={Nature Communications}, doi={10.1038/s41467-019-12046-3}, } @article{UBHD-68952647, author={Mátrai, Janka and Cantore, Alessio and Bartholomae, Cynthia C. and Annoni, Andrea and Wang, Wei and Acosta-Sanchez, Abel and Samara-Kuko, Ermira and De Waele, Liesbeth and Ma, Ling and Genovese, Pietro and Damo, Martina and Arens, Anne and Goudy, Kevin and Nichols, Timothy C. and Kalle, Christof von and L. Chuah, Marinee K. and Roncarolo, Maria Grazia and Schmidt, Manfred and VandenDriessche, Thierry and Naldini, Luigi}, title={Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk}, year={2011}, pages={1696-1707}, language={eng}, issn={1527-3350}, volume={53}, number={5}, note={Gesehen am 11.08.2022}, journal={Hepatology}, doi={10.1002/hep.24230}, } @article{UBHD-68260347, author={Mattar, Citra Nurfarah Zaini and Gil-Fariña, Irene and K{\"a}ppel, Christine and Schmidt, Manfred}, title={In utero transfer of adeno-associated viral vectors produces long-term factor IX levels in a cynomolgus macaque model}, year={2017}, pages={1843-1853}, language={eng}, issn={1525-0024}, volume={25}, number={8}, note={Available online 24 April 2017 ; Gesehen am 12.06.2018}, journal={Molecular therapy}, doi={10.1016/j.ymthe.2017.04.003}, } @article{UBHD-68952667, author={Mattar, Citra Nurfarah Zaini and Nathwani, Amit C and Waddington, Simon N and Dighe, Niraja and Kaeppel, Christine and Nowrouzi, Ali and Mcintosh, Jenny and Johana, Nuryanti B and Ogden, Bryan and Fisk, Nicholas M and Davidoff, Andrew M and David, Anna and Peebles, Donald and Valentine, Marcus B and Appelt, Jens-Uwe and Kalle, Christof von and Schmidt, Manfred and Biswas, Arijit and Choolani, Mahesh and Chan, Jerry KY}, title={Stable human FIX expression after 0.9G intrauterine gene transfer of self-complementary adeno-associated viral vector 5 and 8 in macaques}, year={2011}, pages={1950-1960}, language={eng}, issn={1525-0024}, volume={19}, number={11}, note={Elektronische Reproduktion der Druckausgabe ; Gesehen am 11.08.2022}, journal={Molecular therapy}, doi={10.1038/mt.2011.107}, } @article{UBHD-68090495, author={Molina-Estévez, Francisco Javier and Nowrouzi, Ali and Kalle, Christof von and Schmidt, Manfred}, title={Lentiviral-mediated gene therapy in fanconi anemia-a mice reveals long-term engraftment and continuous turnover of corrected HSCs}, year={2015}, pages={550-562}, language={eng}, issn={1875-5631}, volume={15}, number={6}, note={Gesehen am 01.03.2017}, journal={Current gene therapy}, doi={10.2174/1566523215666150929110903}, } @article{UBHD-68052573, author={Negre, Olivier and Bartholom{\"a}, Cynthia C. and Deichmann, Annette and Fronza, Raffaele and Schmidt, Manfred and Kalle, Christof von}, title={Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease}, year={2015}, pages={64-81}, language={eng}, issn={1875-5631}, volume={15}, number={1}, note={Gesehen am 18.11.2016}, journal={Current gene therapy}, doi={10.2174/1566523214666141127095336}, } @article{UBHD-68627845, author={Negre, Olivier and Bartholom{\"a}, Cynthia C. and Deichmann, Annette and Fronza, Raffaele and Schmidt, Manfred and Kalle, Christof von}, title={Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease}, year={2015}, pages={64-81}, language={eng}, issn={1875-5631}, volume={15}, number={1}, note={Gesehen am 17.08.2020}, journal={Current gene therapy}, doi={10.2174/1566523214666141127095336}, } @article{UBHD-68969371, author={Nowrouzi, Ali and Glimm, Hanno and Kalle, Christof von and Schmidt, Manfred}, title={Retroviral vectors}, subtitle={post entry events and genomic alterations}, year={2011}, pages={429-455}, language={eng}, issn={1999-4915}, volume={3}, note={Gesehen am 29.09.2022 ; This article belongs to the special issue "Retroviral vectors"}, journal={Viruses}, doi={10.3390/v3050429}, } @article{UBHD-67999207, author={Oliveira, Giacomo and Ruggiero, Eliana and Fronza, Raffaele and Lulay, Christina and Kalle, Christof von and Schmidt, Manfred}, title={Erratum for the Research Article: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory}, year={2015}, language={eng}, issn={1946-6242}, volume={7(2015}, note={Gesehen am 23.06.2016}, journal={Science translational medicine}, doi={10.1126/scitranslmed.aaf1040}, } @article{UBHD-67842397, author={Oliveira, Giacomo and Ruggiero, Eliana and Schmidt, Manfred and Kalle, Christof von}, title={Long-Term immunological profile of patients treated with haploidentical HSCT and TK-cells to study the requirements of memory T cell persistence}, year={2014}, pages={1 S.}, language={eng}, issn={1528-0020}, volume={124(2014}, note={Gesehen am 07.07.2015}, journal={Blood}, } @article{UBHD-67999206, author={Oliveira, Giacomo and Ruggiero, Eliana and Fronza, Raffaele and Lulay, Christina and Kalle, Christof von and Schmidt, Manfred}, title={Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory}, year={2015}, language={eng}, issn={1946-6242}, volume={7(2015}, note={Gesehen am 23.06.2016}, journal={Science translational medicine}, doi={10.1126/scitranslmed.aac8265}, } @article{UBHD-68514215, author={Osborn, Mark J. and Webber, Beau R and Knipping, Friederike and Lonetree, Cara-lin and Tennis, Nicole and DeFeo, Anthony P and McElroy, Amber N and Starker, Colby G and Lee, Catherine and Merkel, Sarah and Lund, Troy C and Kelly-Spratt, Karen S and Jensen, Michael C and Voytas, Daniel F and Kalle, Christof von and Schmidt, Manfred and Gabriel, Richard and Hippen, Keli L and Miller, Jeffrey S and Scharenberg, Andrew M and Tolar, Jakub and Blazar, Bruce R}, title={Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases}, year={2016}, pages={570-581}, language={eng}, issn={1525-0024}, volume={24}, number={3}, note={Gesehen am 13.03.2020}, journal={Molecular therapy}, doi={10.1038/mt.2015.197}, } @article{UBHD-68115412, author={Osborn, Mark J. and Gabriel, Richard and Kalle, Christof von and Schmidt, Manfred}, title={Fanconi anemia gene editing by the CRISPR/Cas9 system}, year={2014}, pages={114-126}, language={eng}, issn={1557-7422}, volume={26}, number={2}, note={Gesehen am 03.05.2017}, journal={Human gene therapy}, doi={10.1089/hum.2014.111}, } @article{UBHD-68141570, author={Papanikolaou, Eleni and Paruzynski, Anna and Deichmann, Annette and Schmidt, Manfred and Kalle, Christof von}, title={Cell cycle status of CD34+ hemopoietic stem cells determines lentiviral integration in actively transcribed and development-related genes}, year={2015}, pages={683-696}, language={eng}, issn={1525-0024}, volume={23}, number={4}, note={Gesehen am 24.07.2017 ; Im Titel ist "+" in CD34+ hochgestellt}, journal={Molecular therapy}, doi={10.1038/mt.2014.246}, } @article{UBHD-69089367, author={Paruzynski, Anna and Arens, Anne and Gabriel, Richard and Bartholom{\"a}, Cynthia C. and Scholz, Simone and Wang, Wei and Wolf, Stephan and Glimm, Hanno and Schmidt, Manfred and Kalle, Christof von}, title={Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing}, year={2010}, pages={1379-1395}, language={eng}, issn={1750-2799}, volume={5}, number={8}, note={Gesehen am 26.06.2023}, journal={Nature protocols}, doi={10.1038/nprot.2010.87}, } @article{UBHD-67966106, author={Petri, Karl and Fronza, Raffaele and Gabriel, Richard and Schmidt, Manfred}, title={Comparative next-generation sequencing of adeno-associated virus inverted terminal repeats}, year={2014}, pages={269-273}, language={eng}, issn={1940-9818}, volume={56}, number={5}, note={DOI funktioniert nicht, gesehen am 12.04.2016}, journal={BioTechniques}, doi={10.2144/000114170}, } @article{UBHD-68106320, author={Petri, Karl and Gabriel, Richard and Fronza, Raffaele and Afzal, Saira and K{\"a}ppel, Christine and Schmidt, Manfred}, title={Presence of a trs-like motif promotes rep-mediated wild-type adeno-associated virus type 2 integration}, year={2015}, pages={7428-7432}, language={eng}, issn={1098-5514}, volume={89}, number={14}, note={Gesehen am 04.04.2017}, journal={Journal of virology}, doi={10.1128/JVI.00426-15}, } @article{UBHD-68069522, author={Richards, David and Ruggiero, Eliana and Schmidt, Manfred and Kalle, Christof von}, title={The contained self-reactive peripheral T cell repertoire}, subtitle={size, diversity, and cellular composition}, year={2015}, pages={2067-2079}, language={eng}, issn={1550-6606}, volume={195}, number={5}, note={Gesehen am 05.01.2017}, journal={The journal of immunology}, doi={10.4049/jimmunol.1500880}, } @article{UBHD-68563160, author={Rio, Paula and Navarro, Susana and Wei, Wang and Sánchez-Domínguez, Rebeca and Pujol, Roser M. and Segovia, José C. and Bogliolo, Massimo and Merino, Eva and Wu, Ning and Salgado, Rocío and Lamana, María L. and Yañez, Rosa M. and Casado, José A. and Giménez, Yari and Román-Rodríguez, Francisco J. and Álvarez, Lara and Alberquilla, Omaira and Raimbault, Anna and Guenechea, Guillermo and Lozano, M. Luz and Cerrato, Laura and Hernando, Miriam and Gálvez, Eva and Hladun, Raquel and Giralt, Irina and Barquinero, Jordi and Galy, Anne and Andoín, Nagore García de and López, Ricardo and Catalá, Albert and Schwartz, Jonathan D. and Surrallés, Jordi and Soulier, Jean and Schmidt, Manfred and Heredia, Cristina Díaz de and Sevilla, Julián and Bueren, Juan A.}, title={Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia}, year={2019}, pages={1396-1401}, language={eng}, issn={1546-170X}, volume={25}, number={9}, note={Gesehen am 08.04.2020}, journal={Nature medicine}, doi={10.1038/s41591-019-0550-z}, } @article{UBHD-68066581, author={Ruggiero, Eliana and Nicolay, Jan Peter and Fronza, Raffaele and Arens, Anne and Paruzynski, Anna and Nowrouzi, Ali and Lulay, Christina and Schneider, Sven and Goerdt, Sergij and Glimm, Hanno and Schmidt, Manfred and Kalle, Christof von}, title={High-resolution analysis of the human T-cell receptor repertoire}, year={2015}, language={eng}, issn={2041-1723}, volume={6(2015) Artikel-Nummer 8081}, number={7 Seiten}, note={Gesehen am 20.12.2016}, journal={Nature Communications}, doi={10.1038/ncomms9081}, } @article{UBHD-67860407, author={Saeed, Muhammad and Bartholom{\"a}, Cynthia C. and Knopf, Malaika and Kalle, Christof von and Schmidt, Manfred}, title={Comparison between several integrase-defective lentiviral vectors reveals increased integration of an HIV vector bearing a D167H mutant}, year={2014}, pages={12 S.}, language={eng}, issn={2162-2531}, volume={3(2014) Artikel-Nr.e213}, number={12S}, note={Gesehen am 18.08.2015}, journal={Molecular therapy}, doi={10.1038/mtna.2014.65}, } @article{UBHD-68638440, author={Schenkwein, Diana and Afzal, Saira and Nousiainen, Alisa and Schmidt, Manfred and Yl{\"a}-Herttuala, Seppo}, title={Efficient nuclease-directed integration of lentivirus vectors into the human ribosomal DNA locus}, year={2020}, pages={1858-1875}, language={eng}, issn={1525-0024}, volume={28}, number={8}, note={Gesehen am 17.09.2020}, journal={Molecular therapy}, doi={10.1016/j.ymthe.2020.05.019}, } @book{UBHD-9713223, author={Schmidt, Manfred}, title={Hepatische Triglyceridlipase und Tissue factor pathway inhibitor im Postheparinplasma: Einfluß auf den Gerinnungsfaktor Xa}, year={1997}, pages={IV, 121 Bl.}, language={ger}, note={Nicht f{\"u}r den Austausch}, school={Heidelberg, Univ., Diss., 1997}, library={UB [Signatur: 97 U 245] ; UW [Signatur: Diss. 97.59]}, } @article{UBHD-68579233, author={Schmidt, Manfred and Gil-Fariña, Irene and B{\"u}ning, Hildegard}, title={Reply to “Wild-type AAV insertions in hepatocellular carcinoma do not inform debate over genotoxicity risk of vectorized AAV”}, year={2016}, pages={661-662}, language={eng}, issn={1525-0024}, volume={24}, number={4}, note={Gesehen am 19.05.2020}, journal={Molecular therapy}, doi={10.1038/mt.2016.48}, } @article{UBHD-68114454, author={Sch{\"o}nfeld, Kurt and Holtgreve-Grez, Heidi and Jauch, Anna and Schmidt, Manfred}, title={Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor}, year={2015}, pages={330-338}, language={eng}, issn={1525-0024}, volume={23}, number={2}, note={Published online: 9 December 2014 ; Gesehen am 28.04.2017}, journal={Molecular therapy}, doi={10.1038/mt.2014.219}, } @article{UBHD-68286536, author={Scholz, Simone and Fronza, Raffaele and Bartholom{\"a}, Cynthia C. and Kalle, Christof von and Gil-Fariña, Irene and Schmidt, Manfred}, title={Lentiviral vector promoter is decisive for aberrant transcript formation}, year={2017}, pages={875-885}, language={eng}, issn={1557-7422}, volume={28}, number={10}, note={Online ahead of print: August 18, 2017 ; Gesehen am 18.07.2018}, journal={Human gene therapy}, doi={10.1089/hum.2017.162}, } @article{UBHD-68432928, author={Senís Herrero, Elena and Mosteiro, Lluc and Wilkening, Stefan and Wiedtke, Ellen and Nowrouzi, Ali and Afzal, Saira and Fronza, Raffaele and Landerer, Henrik and Abad, Maria and Niopek, Dominik and Schmidt, Manfred and Serrano, Manuel and Grimm, Dirk}, title={AAV vector-mediated in vivo reprogramming into pluripotency}, year={2018}, pages={14 S.}, language={eng}, issn={2041-1723}, volume={9(2018) Article number: 2651}, number={14 Seiten}, note={Gesehen am 25.09.2019}, journal={Nature Communications}, doi={10.1038/s41467-018-05059-x}, } @article{UBHD-68440068, author={Shangaris, Panicos and Wei, Wang and Schmidt, Manfred}, title={In utero gene therapy (IUGT) using GLOBE lentiviral vector phenotypically corrects the heterozygous humanised mouse model and its progress can be monitored using MRI techniques}, year={2019}, pages={1-17}, language={eng}, issn={2045-2322}, volume={9}, number={Artikel-ID 11592}, note={Gesehen am 14.10.2019}, journal={Scientific reports}, doi={10.1038/s41598-019-48078-4}, } @article{UBHD-68069065, author={Siler, Ulrich and Paruzynski, Anna and Holtgreve-Grez, Heidi and Jauch, Anna and Kalle, Christof von and Schmidt, Manfred}, title={Successful combination of cequential gene therapy and rescue allo-HSCT in two children with X-CGD}, subtitle={importance of timing}, year={2015}, pages={416-427}, language={eng}, issn={1875-5631}, volume={15}, number={4}, note={Gesehen am 04.01.2017}, journal={Current gene therapy}, doi={10.2174/1566523215666150515145255}, } @article{UBHD-68587873, author={Siler, Ulrich and Paruzynski, Anna and Holtgreve-Grez, Heidi and Kuzmenko, Elena and Koehl, Ulrike and Renner, Eleonore D. and Alhan, Canan and de Loosdrecht, Arjan A. van and Schw{\"a}ble, Joachim and Pfluger, Thomas and Tchinda, Joelle and Schmugge, Markus and Jauch, Anna and Naundorf, Sonja and K{\"u}hlcke, Klaus and Notheis, Gundula and G{\"u}ngor, Tayfun and Kalle, Christof von and Schmidt, Manfred and Grez, Manuel and Seger, Reinhard and Reichenbach, Janine}, title={Successful combination of sequential gene therapy and rescue Allo-HSCT in two children with X-CGD$iImportance of timing}, year={2015}, pages={416-427}, language={eng}, issn={1875-5631}, volume={15}, number={4}, note={Gesehen am 17.06.2020}, journal={Current gene therapy}, doi={10.2174/1566523215666150515145255}, } @article{UBHD-69140844, author={Stein, Stefan and Ott, Marion G. and Schultze-Straßer, Stephan and Jauch, Anna and Burwinkel, Barbara and Kinner, Andrea and Schmidt, Manfred and Kr{\"a}mer, Alwin and Schw{\"a}ble, Joachim and Glimm, Hanno and K{\"o}hl, Ulrike and Preiss, Carolin and Ball, Claudia R. and Martin, Hans and G{\"o}hring, Gudrun and Schwarzw{\"a}lder, Kerstin and Hofmann, Wolf-Karsten and Karakaya, Kadin and Tchatchou, Sandrine and Yang, Rongxi and Reinecke, Petra and K{\"u}hlcke, Klaus and Schlegelberger, Brigitte and Thrasher, Adrian J. and Hoelzer, Dieter and Seger, Reinhard and Kalle, Christof von and Grez, Manuel}, title={Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease}, year={2010}, pages={198-204}, language={eng}, issn={1546-170X}, volume={16}, number={2}, note={Gesehen am 08.11.2023}, journal={Nature medicine}, doi={10.1038/nm.2088}, } @article{UBHD-67949827, author={Stephan, Christoph and Baldauf, Hanna-Mari and Barry, Joanne and Giordano, Frank Anton and Bartholom{\"a}, Cynthia C. and Schmidt, Manfred and Maier-Laufs, Stephanie and Kaderali, Lars and Keppler, Oliver Till}, title={Impact of raltegravir on HIV-1 RNA and DNA forms following initiation of antiretroviral therapy in treatment-naive patients}, year={2014}, pages={2809-2818}, language={eng}, issn={1460-2091}, volume={69}, number={10}, note={Gesehen am 01.03.2016}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dku213}, } @article{UBHD-69067726, author={Suleman, Saqlain and Payne, Annette and Bowden, Johnathan and Haque, Sharmin Al and Zahn, Marco and Fawaz, Serena and Khalifa, Mohammad S. and Jobling, Susan and Hay, David and Franco, Matteo and Fronza, Raffaele and Wang, Wei and Strobel-Freidekind, Olga and Deichmann, Annette and Takeuchi, Yasuhiro and Waddington, Simon N. and Gil-Farina, Irene and Schmidt, Manfred and Themis, Michael}, title={HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival}, year={2022}, pages={720-729}, language={eng}, issn={1476-5462}, volume={29}, number={12}, note={Gesehen am 21.04.2023}, journal={Gene therapy}, doi={10.1038/s41434-022-00335-4}, } @article{UBHD-68088488, author={Sundarasetty, Bala Sai and Ruggiero, Eliana and Fronza, Raffaele and Schmidt, Manfred and Kalle, Christof von}, title={Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation}, year={2015}, pages={19 S.}, language={eng}, issn={1479-5876}, volume={13(2015) Artikel-Nummer 240}, number={19 Seiten}, note={Gesehen am 23.02.2017}, journal={Journal of translational medicine}, doi={10.1186/s12967-015-0599-5}, } @article{UBHD-68067866, author={Sundarasetty, Bala Sai and Ruggiero, Eliana and Schmidt, Manfred and Kalle, Christof von}, title={Lentivirus-induced ‘Smart’ dendritic cells}, subtitle={pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma}, year={2015}, pages={707-720}, language={eng}, issn={1476-5462}, volume={22}, number={9}, note={Gesehen am 22.12.2016}, journal={Gene therapy}, doi={10.1038/gt.2015.43}, } @article{UBHD-69121781, author={Tacke, Marlene and Ball, Claudia R. and Schmidt, Manfred and Klingenberg, Silke and Maurer, Birgitta and Fessler, Sylvia and Eaves, Connie J. and Kalle, Christof von and Glimm, Hanno}, title={The inherent differentiation program of short-term hematopoietic repopulating cells changes during human ontogeny}, year={2010}, pages={621-628}, language={eng}, issn={1557-8534}, volume={19}, number={5 vom: Mai}, note={Erstmals am 29 Sep 2009 online ver{\"o}ffentlicht ; Gesehen am 14.09.2023}, journal={Stem Cells and Development}, doi={10.1089/scd.2009.0202}, } @article{UBHD-68984054, author={Tolar, Jakub and Adair, Jennifer E and Antoniou, Michael and Bartholom{\"a}, Cynthia C. and Becker, Pamela S and Blazar, Bruce R and Bueren, Juan and Carroll, Thomas and Cavazzana-Calvo, Marina and Clapp, D Wade and Dalgleish, Robert and Galy, Anne and Gaspar, H Bobby and Hanenberg, Helmut and Kalle, Christof von and Kiem, Hans-Peter and Lindeman, Dirk and Naldini, Luigi and Navarro, Susana and Renella, Raffaele and Rio, Paula and Sevilla, Julián and Schmidt, Manfred and Verhoeyen, Els and Wagner, John E and Williams, David A and Thrasher, Adrian J}, title={Stem cell gene therapy for Fanconi anemia}, subtitle={report from the 1st International Fanconi anemia gene therapy working group meeting}, year={2011}, pages={1193-1198}, language={eng}, issn={1525-0024}, volume={19}, number={7 vom: Juli}, note={Gesehen am 10.11.2022 ; Erstmals am 14. Dezember 2016 online ver{\"o}ffentlicht}, journal={Molecular therapy}, doi={10.1038/mt.2011.78}, } @article{UBHD-68331220, author={Wang, Wei and Fronza, Raffaele and Schmidt, Manfred}, title={The clonal fate of live cells}, year={2017}, pages={93-95}, language={eng}, issn={2329-0501}, volume={5}, note={Gesehen am 22.11.2018}, journal={Molecular therapy}, doi={10.1016/j.omtm.2017.03.007}, } @article{UBHD-68794519, author={Weischenfeldt, Joachim and Simon, Ronald and Feuerbach, Lars and Schlangen, Karin and Weichenhan, Dieter and Minner, Sarah and Wuttig, Daniela and Warnatz, Hans-J{\"o}rg and Stehr, Henning and Rausch, Tobias and J{\"a}ger, Natalie and Gu, Lei and Bogatyrëva, Olga and St{\"u}tz, Adrian M. and Claus, Rainer and Eils, J{\"u}rgen and Eils, Roland and Gerh{\"a}user, Clarissa and Huang, Po-Hsien and Hutter, Barbara and Kabbe, Rolf and Lawerenz, Christian and Radomski, Sylwester and Bartholomae, Cynthia C. and F{\"a}lth Savitski, Maria and Gade, Stephan and Schmidt, Manfred and Amschler, Nina and Haß, Thomas and Galal, Rami and Gjoni, Jovisa and Kuner, Ruprecht and Baer, Constance and Masser, Sawinee and Kalle, Christof von and Zichner, Thomas and Benes, Vladimir and Raeder, Benjamin and Mader, Malte and Amstislavskiy, Vyacheslav and Avci, Meryem and Lehrach, Hans and Parkhomchuk, Dmitri and Sultan, Marc and Burkhardt, Lia and Graefen, Markus and Huland, Hartwig and Kluth, Martina and Krohn, Antje and Sirma, H{\"u}seyin and Stumm, Laura and Steurer, Stefan and Grupp, Katharina and S{\"u}ltmann, Holger and Sauter, Guido and Plass, Christoph and Brors, Benedikt and Yaspo, Marie-Laure and Korbel, Jan Oliver and Schlomm, Thorsten}, title={Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer}, year={2013}, pages={159-170}, language={eng}, issn={1878-3686}, volume={23}, number={2}, note={Gesehen am 28.10.2021}, journal={Cancer cell}, doi={10.1016/j.ccr.2013.01.002}, } @article{UBHD-68284478, author={W{\"u}nsche, Peer and Eckert, Elias Simon Peter and Fronza, Raffaele and Gil-Fariña, Irene and Schmidt, Manfred and Kalle, Christof von and Herbst, Friederike and Glimm, Hanno}, title={Mapping active gene-regulatory regions in human repopulating long-term HSCs}, year={2018}, pages={132-146}, language={eng}, issn={1875-9777}, volume={23}, number={1}, note={Gesehen am 11.07.2018}, journal={Cell stem cell}, doi={10.1016/j.stem.2018.06.003}, } @article{UBHD-68722253, author={Xydia, Maria and Rahbari, Raheleh and Ruggiero, Eliana and Macaulay, Iain and Tarabichi, Maxime and Lohmayer, Robert and Wilkening, Stefan and Michels, Tillmann and Brown, Daniel and Vanuytven, Sebastiaan and Mastitskaya, Svetlana and Laidlaw, Sean and Grabe, Niels and Pritsch, Maria and Fronza, Raffaele and Hexel, Klaus and Schmitt, Steffen and M{\"u}ller-Steinhardt, Michael and Halama, Niels and Domschke, Christoph and Schmidt, Manfred and Kalle, Christof von and Sch{\"u}tz, Florian and Voet, Thierry and Beckhove, Philipp}, title={Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients}, year={2021}, pages={1-18}, language={eng}, issn={2041-1723}, volume={12}, number={Artikel-ID 1119}, note={Gesehen am 11.08.2021}, journal={Nature Communications}, doi={10.1038/s41467-021-21297-y}, } @article{UBHD-69205093, author={Zavidij, Oksana and Ball, Claudia R. and Herbst, Friederike and Fessler, Sylvia and Schmidt, Manfred and Kalle, Christof von and Glimm, Hanno}, title={Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation}, year={2010}, pages={5023-5025}, language={eng}, issn={1528-0020}, volume={115}, number={24 vom: Juni}, note={Gesehen am 17.04.2024}, journal={Blood}, doi={10.1182/blood-2010-02-271528}, }