@article{UBHD-68286169, author={Bingel, Corinna and Sill, Martin and Peterziel, Heike and Milde, Till and Witt, Olaf and Oehme, Ina}, title={Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance}, year={2017}, pages={16 S.}, language={eng}, issn={2041-4889}, volume={8(2017}, note={Gesehen am 17.07.2018}, journal={Cell death & disease}, doi={10.1038/cddis.2017.398}, } @article{UBHD-69010539, author={B{\"o}ck, Barbara and Tagscherer, Katrin and Faßl, Anne and Kr{\"a}mer, Anika and Oehme, Ina and Zentgraf, Hanswalter and Keith, Martina and Roth, Wilfried}, title={The PEA-15 protein regulates autophagy via activation of JNK}, year={2010}, pages={21644-21654}, language={eng}, issn={1083-351X}, volume={285}, number={28}, note={Gesehen am 26.01.2023}, journal={The journal of biological chemistry}, doi={10.1074/jbc.M109.096628}, } @article{UBHD-68295715, author={Brocks, David and Schott, Johanna and Oehme, Ina and Witt, Olaf and Mallm, Jan-Philipp and Rippe, Karsten and Stoecklin, Georg}, title={DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats}, year={2017}, pages={1052-1060}, language={eng}, issn={1546-1718}, volume={49}, number={7}, note={Gesehen am 15.08.2018}, journal={Nature genetics}, doi={10.1038/ng.3889}, } @article{UBHD-68341774, author={Buhl, Juliane and Selt, Florian and Hielscher, Thomas and Ecker, Jonas and Sahm, Felix and Ridinger, Johannes and Usta, Diren and Wefers, Annika K. and Remke, Marc and Pusch, Stefan and Oehme, Ina and Tilburg, Cornelis M. van and Kool, Marcel and Deimling, Andreas von and Herold-Mende, Christel and Korshunov, Andrey and Pfister, Stefan and Jones, David T. W. and Witt, Olaf and Milde, Till}, title={The senescence-associated secretory phenotype mediates oncogene-induced senescence in pediatric pilocytic astrocytoma}, year={2019}, pages={1851-1866}, language={eng}, issn={1557-3265}, volume={25}, number={6}, note={Published first: December 7, 2018 ; Gesehen am 18.12.2018}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-18-1965}, } @article{UBHD-68960582, author={Darwish, Salma and Ghazy, Ehab Mohamed Elbassiony and Heimburg, Tino and Herp, Daniel and Zeyen, Patrik René and Salem-Altintas, Rabia and Ridinger, Johannes and Robaa, Dina and Schmidtkunz, Karin and Erdmann, Frank and Schmidt, Matthias and Romier, Christophe and Jung, Manfred and Oehme, Ina and Sippl, Wolfgang}, title={Design, synthesis and biological characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with anti-neuroblastoma activity}, year={2022}, pages={1-31}, language={eng}, issn={1422-0067 and 1661-6596}, volume={23}, note={Gesehen am 06.09.2022}, journal={International journal of molecular sciences}, doi={10.3390/ijms23147535}, } @article{UBHD-68467061, author={Daskalakis, Michael and Brocks, David and Sheng, Yi-Hua and Islam, Md Saiful and Ressnerova, Alzbeta and Assenov, Yassen and Milde, Till and Oehme, Ina and Witt, Olaf and Goyal, Ashihs and K{\"u}hn, Alexander and Hartmann, Mark and Weichenhan, Dieter and Jung, Manfred and Plass, Christoph}, title={Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors}, year={2018}, pages={811-822}, language={eng}, issn={1551-4005}, volume={17}, number={7}, note={Gesehen am 10.12.2019}, journal={Cell cycle}, doi={10.1080/15384101.2018.1442623}, } @article{UBHD-67322240, author={Deubzer, Hedwig and Schier, Marie Catherine and Oehme, Ina and Lodrini, Marco and Witt, Olaf}, title={HDAC11 is a novel drug target in carcinomas}, year={2013}, pages={2200-2208}, language={eng}, issn={1097-0215}, volume={132}, number={9}, note={Online 1 Oct 2012 ; Gesehen am 14.12.2020}, journal={International journal of cancer}, doi={10.1002/ijc.27876}, } @article{UBHD-68299976, author={Dovzhanskiy, Dmitriy I. and Arnold, Stefanie M. and Hackert, Thilo and Oehme, Ina and Witt, Olaf and Felix, Klaus M. and Giese, Nathalia and Werner, Jens}, title={Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer}, year={2012}, pages={9 S.}, language={eng}, issn={1471-2407}, volume={12(2012) Artikel-Nummer 226}, number={9 Seiten}, note={Gesehen am 29.08.2018}, journal={BMC cancer}, doi={10.1186/1471-2407-12-226}, } @article{UBHD-68746998, author={Ecker, Jonas and Thatikonda, Venu and Sigismondo, Gianluca and Selt, Florian and Valinciute, Gintvile and Oehme, Ina and M{\"u}ller, Carina and Buhl, Juliane and Ridinger, Johannes and Usta, Diren and Qin, Nan and Tilburg, Cornelis M. van and Herold-Mende, Christel and Remke, Marc and Sahm, Felix and Westermann, Frank and Kool, Marcel and Wechsler-Reya, Robert J. and Chavez, Lukas and Krijgsveld, Jeroen and J{\"a}ger, Natalie and Pfister, Stefan and Witt, Olaf and Milde, Till}, title={Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma}, year={2021}, pages={226-239}, language={eng}, issn={1523-5866}, volume={23}, number={2 vom: Feb.}, note={Gesehen am 10.06.2021 ; First published: 21 August 2020}, journal={Neuro-Oncology}, doi={10.1093/neuonc/noaa191}, } @article{UBHD-68638102, author={Fabian, Johannes and Lodrini, Marco and Oehme, Ina and Schier, Marie Catherine and Thole, Theresa Maria and Hielscher, Thomas and Kopp-Schneider, Annette and Opitz, Lennart and Capper, David and Deimling, Andreas von and Rettig, Inga Edeltraud and Milde, Till and Mahlknecht, Ulrich Rudolph and Westermann, Frank and Popanda, Odilia and Roels, Frederik and Hero, Barbara and Berthold, Frank and Fischer, Matthias and Kulozik, Andreas and Witt, Olaf and Deubzer, Hedwig}, title={GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3}, year={2014}, pages={2604-2616}, language={eng}, issn={1538-7445}, volume={74}, number={9}, note={Gesehen am 16.09.2020}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-13-1904}, } @article{UBHD-68712648, author={Fiegler, Nathalie and Textor, Sonja and Arnold, Annette and R{\"o}lle, Alexander and Oehme, Ina and Breuhahn, Kai and Moldenhauer, Gerhard and Witzens-Harig, Mathias and Cerwenka, Adelheid}, title={Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells}, year={2013}, pages={684-693}, language={eng}, issn={1528-0020}, volume={122}, number={5}, note={Gesehen am 15.03.2021}, journal={Blood}, doi={10.1182/blood-2013-02-482513}, } @article{UBHD-68896635, author={Gatzweiler, Charlotte and Ridinger, Johannes and Herter, Sonja and Gerloff, Xenia F. and ElHarouni, Dina and Berker, Yannick and Imle, Roland and Schmitt, Lukas and Kreth, Sina and Stainczyk, Sabine and Ayhan, Simay and Najafi, Sara and Krunic, Damir and Frese, Karen S. and Meder, Benjamin and Reuss, David and Fiesel, Petra and Schramm, Kathrin and Blattner-Johnson, Mirjam and Jones, David T. W. and Banito, Ana and Westermann, Frank and Oppermann, Sina and Milde, Till and Peterziel, Heike and Witt, Olaf and Oehme, Ina}, title={Functional therapeutic target validation using pediatric zebrafish xenograft models}, year={2022}, pages={1-24}, language={eng}, issn={2072-6694}, volume={14}, note={Gesehen am 29.03.2022}, journal={Cancers}, doi={10.3390/cancers14030849}, } @article{UBHD-68415013, author={Géraldy, Magalie and Morgen, Michael and Ridinger, Johannes and Oehme, Ina and Witt, Olaf}, title={Selective inhibition of histone deacetylase 10}, subtitle={hydrogen bonding to the gatekeeper residue is implicated}, year={2019}, pages={4426-4443}, language={eng}, issn={1520-4804}, volume={62}, number={9}, note={Gesehen am 01.08.2019}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.8b01936}, } @article{UBHD-69081323, author={Herp, Daniel and Ridinger, Johannes and Robaa, Dina and Shinsky, Stephen A. and Schmidtkunz, Karin and Yesiloglu, Talha Z. and Bayer, Theresa Yasmin Charlotte and Steimbach, Raphael R. and Herbst-Gervasoni, Corey J. and Merz, Annika and Romier, Christophe and Sehr, Peter and Gunkel, Nikolas and Miller, Aubry K. and Christianson, David W. and Oehme, Ina and Sippl, Wolfgang and Jung, Manfred}, title={First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement}, year={2022}, pages={1-28}, language={eng}, issn={1439-7633}, volume={23}, note={Published online: 24 May 2022}, journal={ChemBioChem}, doi={10.1002/cbic.202200180}, } @article{UBHD-68436861, author={J{\"a}nsch, Niklas and Witt, Olaf and Oehme, Ina}, title={The enzyme activity of histone deacetylase 8 is modulated by a redox-switch}, year={2019}, pages={60-67}, language={eng}, issn={2213-2317}, volume={20}, note={Available online 27 September 2018 ; Gesehen am 09.10.2019}, journal={Redox Biology}, doi={10.1016/j.redox.2018.09.013}, } @article{UBHD-69369015, author={Kasan, Merve and Geyer, Florian H. and Siebenlist, Jana and Sill, Martin and {\"O}llinger, Rupert and Faehling, Tobias and de Álava, Enrique and Surdez, Didier and Dirksen, Uta and Oehme, Ina and Scotlandi, Katia and Delattre, Olivier and M{\"u}ller-Nurasyid, Martina and Rad, Roland and Strauch, Konstantin and Gr{\"u}newald, Thomas G. P. and Cidre-Aranaz, Florencia}, title={Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines}, year={2025}, pages={1-9}, language={eng}, issn={2041-1723}, volume={16}, note={Gesehen am 25.07.2025}, journal={Nature Communications}, doi={10.1038/s41467-024-55340-5}, } @article{UBHD-68747378, author={Klionsky, Daniel and Hamacher-Brady, Anne and Nussbaum-Krammer, Carmen and Oehme, Ina and Rudolf, R{\"u}diger}, title={Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)}, year={2021}, pages={1-382}, language={eng}, issn={1554-8635}, volume={17}, number={1}, journal={Autophagy}, doi={10.1080/15548627.2020.1797280}, } @article{UBHD-68576442, author={Klionsky, Daniel and Oehme, Ina and Hamacher-Brady, Anne and Rasse, Tobias M. and Schuck, Sebastian and Ebrahimi-Fakhari, Darius and Fortunato, Franco and Lemberg, Marius and Parlato, Rosanna}, title={Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)}, year={2016}, pages={1-222}, language={eng}, issn={1554-8635}, volume={12}, number={1}, note={Gesehen am 13.05.2020}, journal={Autophagy}, doi={10.1080/15548627.2015.1100356}, } @article{UBHD-69323093, author={Kocher, Daniela and Cao, Lei and Guiho, Romain and Langhammer, Melanie and Lai, Yun-Lu and Becker, Pauline and Hamdi, Hiba and Friedel, Dennis and Selt, Florian and Vonh{\"o}ren, David and Zaman, Julia and Valinciute, Gintvile and Herter, Sonja and Picard, Daniel and Rettenmeier, Johanna and Maaß, Kendra K. and Pajtler, Kristian Wilfried and Remke, Marc and Deimling, Andreas von and Pusch, Stefan and Pfister, Stefan and Oehme, Ina and Jones, David T. W. and Halbach, Sebastian and Brummer, Tilman and Martinez-Barbera, Juan Pedro and Witt, Olaf and Milde, Till and Sigaud, Romain}, title={Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines}, year={2024}, pages={317-332}, language={eng}, issn={1573-7373}, volume={168}, number={2 vom: Juni}, note={Gesehen am 28.03.2025}, journal={Journal of neuro-oncology}, doi={10.1007/s11060-024-04672-9}, } @article{UBHD-68616781, author={Koeneke, Emily and Witt, Olaf and Oehme, Ina}, title={HDAC Family members intertwined in the regulation of autophagy}, subtitle={a druggable vulnerability in aggressive tumor entities}, year={2015}, pages={135-168}, language={eng}, issn={2073-4409}, volume={4}, number={2}, note={Gesehen am 14.07.2020}, journal={Cells}, doi={10.3390/cells4020135}, } @article{UBHD-68753849, author={K{\"o}rholz, Katharina and Ridinger, Johannes and Krunic, Damir and Najafi, Sara and Gerloff, Xenia F. and Frese, Karen S. and Meder, Benjamin and Peterziel, Heike and Vega-Rubín-de-Celis, Silvia and Witt, Olaf and Oehme, Ina}, title={Broad-spectrum HDAC inhibitors promote autophagy through FOXO transcription factors in neuroblastoma}, year={2021}, pages={1-18}, language={eng}, issn={2073-4409}, volume={10}, note={Gesehen am 29.06.2021}, journal={Cells}, doi={10.3390/cells10051001}, } @article{UBHD-68465624, author={Kolbinger, Fiona and Ridinger, Johannes and Heimburg, Tino and Bayer, Theresa Yasmin Charlotte and Sippl, Wolfgang and Gunkel, Nikolas and Westermann, Frank and Witt, Olaf and Oehme, Ina}, title={The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines}, year={2018}, pages={2649-2664}, language={eng}, issn={1432-0738}, volume={92}, number={8}, journal={Archives of toxicology}, doi={10.1007/s00204-018-2234-8}, } @article{UBHD-68739690, author={Lodrini, Marco and Oehme, Ina and Schr{\"o}der, Christina and Milde, Till and Schier, Marie Catherine and Kopp-Schneider, Annette and Schulte, Johannes H. and Fischer, Matthias and De Preter, Katleen and Pattyn, Filip and Castoldi, Mirco and Muckenthaler, Martina and Kulozik, Andreas and Westermann, Frank and Witt, Olaf and Deubzer, Hedwig}, title={MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma}, year={2013}, pages={6018-6033}, language={eng}, issn={1362-4962}, volume={41}, number={12}, note={Gesehen am 19.05.2021}, journal={Nucleic acids research}, doi={10.1093/nar/gkt346}, } @article{UBHD-68333887, author={Milde, Till and Hielscher, Thomas and Witt, Hendrik and Kool, Marcel and Deubzer, Hedwig and Oehme, Ina and Lodrini, Marco and Benner, Axel and Deimling, Andreas von and Kulozik, Andreas and Pfister, Stefan and Witt, Olaf and Korshunov, Andrey}, title={Nestin expression identifies ependymoma patients with poor outcome}, year={2012}, pages={848-860}, language={eng}, issn={1750-3639}, volume={22}, number={6}, note={Gesehen am 29.11.2018}, journal={Brain pathology}, doi={10.1111/j.1750-3639.2012.00600.x}, } @article{UBHD-68955714, author={Milde, Till and Kleber, Susanne and Korshunov, Andrey and Witt, Hendrik and Hielscher, Thomas and Koch, Philipp and Kopp, Hans-Georg and Jugold, Manfred and Deubzer, Hedwig E. and Oehme, Ina and Lodrini, Marco and Gr{\"o}ne, Hermann-Josef and Benner, Axel and Br{\"u}stle, Oliver and Gilbertson, Richard J. and Deimling, Andreas von and Kulozik, Andreas and Pfister, Stefan and Martín-Villalba, Ana and Witt, Olaf}, title={A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat}, year={2011}, pages={1-14}, language={eng}, issn={1432-0533}, volume={122}, note={Gesehen am 19.08.2022}, journal={Acta neuropathologica}, doi={10.1007/s00401-011-0866-3}, } @article{UBHD-69069402, author={Milde, Till and Oehme, Ina and Korshunov, Andrey and Kopp-Schneider, Annette and Remke, Marc and Northcott, Paul and Deubzer, Hedwig and Lodrini, Marco and Taylor, Michael D. and Deimling, Andreas von and Pfister, Stefan and Witt, Olaf}, title={HDAC5 and HDAC9 in medulloblastoma}, subtitle={novel markers for risk stratification and role in tumor cell growth}, year={2010}, pages={3240-3252}, language={eng}, issn={1557-3265}, volume={16}, number={12}, note={Gesehen am 26.04.2023}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-10-0395}, } @article{UBHD-68792687, author={M{\"u}ller, Michael and R{\"o}sch, Lisa and Najafi, Sara and Gatzweiler, Charlotte and Ridinger, Johannes and Gerloff, Xenia F. and Jones, David T. W. and Baßler, Jochen and Kreth, Sina and Stainczyk, Sabine and Frese, Karen S. and Meder, Benjamin and Westermann, Frank and Milde, Till and Peterziel, Heike and Witt, Olaf and Oehme, Ina}, title={Combining APR-246 and HDAC-inhibitors}, subtitle={a novel targeted treatment option for neuroblastoma}, year={2021}, pages={1-23}, language={eng}, issn={2072-6694}, volume={13}, note={Gesehen am 22.10.2021}, journal={Cancers}, doi={10.3390/cancers13174476}, } @book{UBHD-68629793, author={Oehme, Ina}, organization={Universit{\"a}t Heidelberg}, title={Histondeacetylasen und die Regulation von Autophagie und Zelldifferenzierung in kindlichen Tumoren des Nervesystems}, address={Heidelberg}, year={2019}, pages={1 Band (verschiedene Seitenz{\"a}hlungen)}, language={eng}, note={Publikationsbasierte Habilitationsschrift bestehend aus einem Text und 9 Zeitschriftenaufs{\"a}tzen}, school={Habilitationsschrift, Ruprecht-Karls-Universit{\"a}t Heidelberg, 2020, Kumulative Habilitationsschrift}, library={UB [Signatur: 2020 U 611]}, } @article{UBHD-67458702, author={Oehme, Ina and Linke, Jan-Peter and B{\"o}ck, Barbara and Milde, Till and Lodrini, Marco and Hartenstein, Bettina and Rettig, Inga Edeltraud and Eckert, Christian and Roth, Wilfried and Kool, Marcel and Kaden, Sylvia and Gr{\"o}ne, Hermann-Josef and Schulte, Johannes Hubertus and Lindner, Sven and Hamacher-Brady, Anne and Brady, Nathan and Deubzer, Hedwig and Witt, Olaf}, title={Histone deacetylase 10 promotes autophagy-mediated cell survival}, year={2013}, pages={E2592-E2601}, language={eng}, issn={0027-8424}, volume={110}, number={28}, journal={Proceedings of the National Academy of Sciences of the United States of America}, } @article{UBHD-68805961, author={Oehme, Ina and Linke, Jan-Peter and B{\"o}ck, Barbara and Milde, Till and Lodrini, Marco and Hartenstein, Bettina and Rettig, Inga Edeltraud and Eckert, Christian and Roth, Wilfried and Kool, Marcel and Kaden, Sylvia and Gr{\"o}ne, Hermann-Josef and Schulte, Johannes Hubertus and Lindner, Sven and Hamacher-Brady, Anne and Brady, Nathan and Deubzer, Hedwig and Witt, Olaf}, title={Histone deacetylase 10 promotes autophagy-mediated cell survival}, year={2013}, pages={E2592-E2601}, language={eng}, issn={1091-6490}, volume={110}, number={28}, note={Gesehen am 29.11.2021}, journal={Proceedings of the National Academy of Sciences of the United States of America}, doi={10.1073/pnas.1300113110}, } @article{UBHD-68805986, author={Oehme, Ina and Lodrini, Marco and Brady, Nathan and Witt, Olaf}, title={Histone deacetylase 10-promoted autophagy as a druggable point of interference to improve the treatment response of advanced neuroblastomas}, year={2013}, pages={2163-2165}, language={eng}, issn={1554-8635}, volume={9}, number={12}, note={Gesehen am 29.11.2021}, journal={Autophagy}, doi={10.4161/auto.26450}, } @article{UBHD-69006827, author={Peterziel, Heike and Jamaladdin, Nora and ElHarouni, Dina and Gerloff, Xenia F. and Herter, Sonja and Fiesel, Petra and Berker, Yannick and Blattner-Johnson, Mirjam and Schramm, Kathrin and Jones, Barbara Christine and Reuss, David and Turunen, Laura and Friedenauer, Aileen and Holland-Letz, Tim and Sill, Martin and Weiser, Lena and Previti, A. Christopher and Balasubramanian, Gnanaprakash and Gerber, Nicolas U. and Gojo, Johannes and Hutter, Caroline and Øra, Ingrid and Lohi, Olli and Kattamis, Antonis and de Wilde, Bram and Westermann, Frank and Tippelt, Stephan and Graf, Norbert and Nathrath, Michaela and Sparber-Sauer, Monika and Sehested, Astrid and Kramm, Christof M. and Dirksen, Uta and Kallioniemi, Olli and Pfister, Stefan and Tilburg, Cornelis M. van and Jones, David T. W. and Saarela, Jani and Pieti{\"a}inen, Vilja and J{\"a}ger, Natalie and Schlesner, Matthias and Kopp-Schneider, Annette and Oppermann, Sina and Milde, Till and Witt, Olaf and Oehme, Ina}, title={Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM}, year={2022}, pages={1-17}, language={eng}, issn={2397-768X}, volume={6}, number={Artikel-ID 94}, note={Gesehen am 17.01.2023}, journal={npj precision oncology}, doi={10.1038/s41698-022-00335-y}, } @article{UBHD-68638234, author={Rettig, Inga Edeltraud and Koeneke, Emily and Trippel, Franziska and Mueller, Wolf C. and Burhenne, J{\"u}rgen and Kopp-Schneider, Annette and Fabian, Johannes and Schober, Andreas and Fernekorn, Uta and Deimling, Andreas von and Deubzer, Hedwig and Milde, Till and Witt, Olaf and Oehme, Ina}, title={Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation}, year={2015}, pages={14 S.}, language={eng}, issn={2041-4889}, volume={Bd. 6}, journal={Cell death & disease}, doi={10.1038/cddis.2015.24}, } @article{UBHD-68488050, author={Ridinger, Johannes and Gunkel, Nikolas and Peterziel, Heike and Schmezer, Peter and Hamacher-Brady, Anne and Witt, Olaf and Oehme, Ina}, title={Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance}, year={2018}, pages={17 S.}, language={eng}, issn={2045-2322}, volume={8(2018) Artikel-Nummer 10039}, number={17 Seiten}, note={Gesehen am 12.02.2020}, journal={Scientific reports}, doi={10.1038/s41598-018-28265-5}, } @article{UBHD-69293300, author={Seiboldt, Till and Zeiser, Constantia and Nguyen, Duy and Çeliky{\"u}rekli, Simay and Herter, Sonja and Najafi, Sara and Stroh-Dege, Alexandra and Meulenbroeks, Chris and Mack, Norman and Salem-Altintas, Rabia and Westermann, Frank and Schlesner, Matthias and Milde, Till and Kool, Marcel and Holland-Letz, Tim and Vogler, Meike and Peterziel, Heike and Witt, Olaf and Oehme, Ina}, title={Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours}, year={2024}, pages={763-777}, language={eng}, issn={1532-1827}, volume={131}, number={4}, note={Gesehen am 22.01.2025}, journal={British journal of cancer}, doi={10.1038/s41416-024-02740-5}, } @article{UBHD-68280852, author={Selt, Florian and Buhl, Juliane and Sahm, Felix and Capper, David and Korshunov, Andrey and Usta, Diren and Brabetz, Sebastian and Ridinger, Johannes and Ecker, Jonas and Oehme, Ina and B{\"a}chli, Heidi and Deimling, Andreas von and Pfister, Stefan and Jones, David T. W. and Witt, Olaf and Milde, Till}, title={Establishment and application of a novel patient-derived KIAA1549}, subtitle={BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing}, year={2017}, pages={11460-11479}, language={eng}, issn={1949-2553}, volume={8}, number={7}, note={Published online: December 17, 2016 ; Gesehen am 04.07.2018}, journal={OncoTarget}, doi={10.18632/oncotarget.14004}, } @article{UBHD-69163993, author={Selt, Florian and El Damaty, Ahmed and Schuhmann, Martin U. and Sigaud, Romain and Ecker, Jonas and Sievers, Philipp and Kocher, Daniela and Herold-Mende, Christel and Oehme, Ina and Deimling, Andreas von and Pfister, Stefan and Sahm, Felix and Jones, David T. W. and Witt, Olaf and Milde, Till}, title={Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T}, subtitle={evaluation of a modeling workflow}, year={2023}, pages={467-478}, language={eng}, issn={1573-7373}, volume={165}, number={3 vom: Nov.}, note={Gesehen am 22.01.2024}, journal={Journal of neuro-oncology}, doi={10.1007/s11060-023-04500-6}, } @article{UBHD-68452719, author={Shen, Jing and Najafi, Sara and St{\"a}ble, Sina and Fabian, Johannes and Koeneke, Emily and Kolbinger, Fiona R. and Wrobel, Jagoda and Meder, Benjamin and Distel, Martin and Heimburg, Tino and Sippl, Wolfgang and Jung, Manfred and Peterziel, Heike and Kranz, Dominique and Boutros, Michael and Westermann, Frank and Witt, Olaf and Oehme, Ina}, title={A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment}, year={2018}, pages={2053-2070}, language={eng}, issn={1476-5403}, volume={25}, journal={Cell death and differentiation}, doi={10.1038/s41418-018-0080-0}, } @article{UBHD-69157322, author={Vollmer, Johanna and Ecker, Jonas and Hielscher, Thomas and Valinciute, Gintvile and Ridinger, Johannes and Jamaladdin, Nora and Peterziel, Heike and Tilburg, Cornelis M. van and Oehme, Ina and Witt, Olaf and Milde, Till}, title={Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells}, year={2023}, pages={617-632}, language={eng}, issn={1573-7373}, volume={164}, number={3}, note={Online ver{\"o}ffentlicht: 3. Oktober 2023 ; Gesehen am 04.01.2024}, journal={Journal of neuro-oncology}, doi={10.1007/s11060-023-04445-w}, } @article{UBHD-68299286, author={Witt, Olaf and Milde, Till and Deubzer, Hedwig and Oehme, Ina and Kulozik, Andreas and Eisenmenger, Andreas and Abel, Ulrich and Karapanagiotou-Schenkel, Irini}, title={Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia}, year={2012}, pages={398-403}, language={eng}, issn={1439-3824}, volume={224}, number={06}, note={Gesehen am 27.08.2018}, journal={Klinische P{\"a}diatrie}, doi={10.1055/s-0032-1323692}, } @article{UBHD-68491596, author={Wolff, Benjamin and J{\"a}nsch, Niklas and Sugiarto, Wisely Oki and Fr{\"u}hschulz, Stefan and Lang, Maraike and Altintas, Rabia and Oehme, Ina and Meyer-Almes, Franz-Josef}, title={Synthesis and structure activity relationship of 1, 3-benzo-thiazine-2-thiones as selective HDAC8 inhibitors}, year={2019}, pages={1-20}, language={eng}, issn={1768-3254}, volume={184}, number={Artikel-ID 111756}, note={Gesehen am 20.02.2020}, journal={European journal of medicinal chemistry}, doi={10.1016/j.ejmech.2019.111756}, } @article{UBHD-68687989, author={Wrobel, Jagoda and Najafi, Sara and Ayhan, Simay and Gatzweiler, Charlotte and Krunic, Damir and Ridinger, Johannes and Milde, Till and Westermann, Frank and Peterziel, Heike and Meder, Benjamin and Distel, Martin and Witt, Olaf and Oehme, Ina}, title={Rapid in vivo validation of HDAC inhibitor-based treatments in neuroblastoma zebrafish xenografts}, year={2020}, language={eng}, issn={1424-8247}, volume={13(2020}, note={Gesehen am 03.02.2021}, journal={Pharmaceuticals}, doi={10.3390/ph13110345}, } @article{UBHD-69195421, author={Zeuner, Simon and Vollmer, Johanna and Sigaud, Romain and Oppermann, Sina and Peterziel, Heike and ElHarouni, Dina and Oehme, Ina and Witt, Olaf and Milde, Till and Ecker, Jonas}, title={Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells}, year={2024}, pages={99-112}, language={eng}, issn={1573-7373}, volume={166}, note={Gesehen am 26.03.2024}, journal={Journal of neuro-oncology}, doi={10.1007/s11060-023-04526-w}, }