@article{UBHD-69221245, author={Bechberger, Maren and Eigenbrod, Tatjana and Boutin, Sébastien and Heeg, Klaus and Bode, K. A.}, title={IL-1β knockout increases the intestinal abundancy of Akkermansia muciniphila}, year={2023}, pages={361-370}, language={eng}, issn={1876-2891}, volume={14}, number={4 vom: Dez.}, note={Online ver{\"o}ffentlicht: 1. September 2023 ; Gesehen am 06.06.2024}, journal={Beneficial microbes}, doi={10.1163/18762891-20220042}, } @article{UBHD-68263932, author={Bekeredjian-Ding, Isabelle and F{\"o}rmer, Sandra and Kirschning, Carsten J{\"u}rgen and Parčina, Marijo and Heeg, Klaus}, title={Poke weed mitogen requires toll-like receptor ligands for proliferative activity in human and murine B lymphocytes}, year={2012}, pages={11 S.}, language={eng}, issn={1932-6203}, volume={7(2012}, note={Published January 4, 2012 ; Gesehen am 21.06.2018}, journal={PLOS ONE}, doi={10.1371/journal.pone.0029806}, } @article{UBHD-69263013, author={Bekeredjian-Ding, Isabelle and Marshall, Anne and Schiller, Martin and Heyder, Petra and Lorenz, Hanns-Martin and Schraven, Burkhart and Bommhardt, Ursula and Heeg, Klaus}, title={TLR9-activating DNA up-regulates ZAP70 via sustained PKB induction in IgM+ B cells}, year={2008}, pages={8267-8277}, language={eng}, issn={0022-1767 and 1048-3233 and 1047-7381}, volume={181}, number={12}, note={Gef{\"o}rdert durch: Deutsche Forschungsgemeinschaft Grants BO1054/2-1 and LO 437/5-3 ; Im Titel ist + hochgestellt}, journal={The journal of immunology}, } @article{UBHD-69313280, author={Boutin, Sébastien and Scherrer, Martin and Sp{\"a}th, Isabel and Kocer, Kaan and Heeg, Klaus and Nurjadi, Dennis}, title={Cross-contamination of carbapenem-resistant Gram-negative bacteria between patients and the hospital environment in the first year of a newly built surgical ward}, year={2024}, pages={118-127}, language={eng}, issn={1532-2939}, volume={144(2024) vom: Feb.}, note={Online ver{\"o}ffentlicht: 9. Dezember 2023 ; Gesehen am 27.02.2025}, journal={The journal of hospital infection}, doi={10.1016/j.jhin.2023.11.016}, } @article{UBHD-69313224, author={Boutin, Sébastien and Welker, S. and Gerigk, Marlis and Miethke, Thomas and Heeg, Klaus and Nurjadi, Dennis}, title={Molecular surveillance of carbapenem-resistant Enterobacterales in two nearby tertiary hospitals to identify regional spread of high-risk clones in Germany, 2019-2020}, year={2024}, pages={126-134}, language={eng}, issn={1532-2939}, volume={149}, note={Online verf{\"u}gbar: 7. Mai 2024, Artikelversion: 7. Juni 2024 ; Gesehen am 27.02.2025}, journal={The journal of hospital infection}, doi={10.1016/j.jhin.2024.04.014}, } @article{UBHD-68680350, author={Decker, Sebastian and Hildebrand, Dagmar and Bruckner, Thomas and Lichtenstern, Christoph and Heeg, Klaus and Weigand, Markus A. and Brenner, Thorsten and Uhle, Florian}, title={Delta-like canonical notch ligand 1 in patients following liver transplantation}, subtitle={a secondary analysis of a prospective cohort study}, year={2020}, language={eng}, issn={2075-4418}, volume={10(2020}, note={Gesehen am 15.01.2020}, journal={Diagnostics}, doi={10.3390/diagnostics10110894}, } @article{UBHD-68569978, author={Eichel, Vanessa and Papan, C. and Boutin, Sébastien and P{\"o}schl, Johannes and Heeg, Klaus and Nurjadi, Dennis}, title={Alteration of antibiotic regimen as an additional control measure in suspected multi-drug-resistant Enterobacter cloacae outbreak in a neonatal intensive care unit}, year={2020}, pages={144-149}, language={eng}, issn={1532-2939}, volume={104}, number={2}, note={Available online 13 September 2019 ; Gesehen am 24.04.2020}, journal={The journal of hospital infection}, doi={10.1016/j.jhin.2019.09.007}, } @article{UBHD-68635888, author={Eichel, Vanessa and Klein, Sabrina and Bootsveld, Carolin and Frank, Uwe and Heeg, Klaus and Boutin, Sébastien and Nurjadi, Dennis}, title={Challenges in interpretation of WGS and epidemiological data to investigate nosocomial transmission of vancomycin-resistant Enterococcus faecium in an endemic region}, subtitle={incorporation of patient movement network and admission screening}, year={2020}, pages={1716-1721}, language={eng}, issn={1460-2091}, volume={75}, number={7}, note={Gesehen am 09.09.2020}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkaa122}, } @article{UBHD-68932268, author={Eichel, Vanessa and Boutin, Sébastien and Frank, Uwe and Weigand, Markus A. and Heininger, Alexandra and Mutters, Nico T. and B{\"u}chler, Markus W. and Heeg, Klaus and Nurjadi, Dennis}, title={Impact of discontinuing contact precautions and enforcement of basic hygiene measures on nosocomial vancomycin-resistant Enterococcus faecium transmission}, year={2022}, pages={120-127}, language={eng}, issn={1532-2939}, volume={121}, note={Available online 30 November 2021 ; Gesehen am 20.06.2022}, journal={The journal of hospital infection}, doi={10.1016/j.jhin.2021.11.020}, } @article{UBHD-68491056, author={Eigenbrod, Tatjana and Reuter, Sandra and Gross, Andrea and Kocer, Kaan and G{\"u}nther, Frank and Zimmermann, Stefan and Heeg, Klaus and Mutters, Nico T. and Nurjadi, Dennis}, title={Molecular characterization of carbapenem-resistant Acinetobacter baumannii using WGS revealed missed transmission events in Germany from 2012-15}, year={2019}, pages={3473-3480}, language={eng}, issn={1460-2091}, volume={74}, number={12}, note={Gesehen am 19.02.2020}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkz360}, } @article{UBHD-68247084, author={Geis, Steffen and Giesen, Nicola and Egerer, Gerlinde and Eisenbach, Christoph and Dreger, Peter and Neben, Kai and Burkhardt, Ulrich and Ho, Anthony Dick and Kr{\"a}usslich, Hans-Georg and Heeg, Klaus and Schnitzler, Paul}, title={Molecular characterization of a respiratory ayncytial virus outbreak in a hematology unit in Heidelberg, Germany}, year={2013}, pages={155-162}, language={eng}, issn={1098-660X}, volume={51}, number={1}, note={Accepted manuscript posted online 24 October 2012 ; Gesehen am 26.04.2018}, journal={Journal of clinical microbiology}, doi={10.1128/JCM.02151-12}, } @article{UBHD-68260803, author={Giesbrecht, Katharina and Eberle, Mariel-Esther and S{\"a}hr, Aline and Bode, Konrad A. and Heeg, Klaus and Hildebrand, Dagmar and Menne, Zach and W{\"o}lfle, Sabine J. and Sahin, Delal and Oberhardt, Valerie}, title={IL-1β as mediator of resolution that reprograms human peripheral monocytes toward a suppressive phenotype}, year={2017}, pages={15 S.}, language={eng}, issn={1664-3224}, volume={8(2017) Artikel-Nummer 899}, number={15 Seiten}, note={Gesehen am 13.06.2018}, journal={Frontiers in immunology}, doi={10.3389/fimmu.2017.00899}, } @article{UBHD-68440650, author={Giesbrecht, Katharina and Heeg, Klaus and Hildebrand, Dagmar}, title={Streptococcal pyrogenic exotoxin A-stimulated monocytes mediate regulatory T-cell accumulation through PD-L1 and Kynurenine}, year={2019}, pages={17 S.}, language={eng}, issn={1422-0067 and 1661-6596}, volume={20(2019}, note={Gesehen am 15.10.2019}, journal={International journal of molecular sciences}, doi={10.3390/ijms20163933}, } @article{UBHD-68826364, author={Giesen, Nicola and Schnitzler, Paul and Geis, Steffen and Puthenparambil, Joe and Benz, Michael Andreas and Alber, Bettina and Luft, Thomas and Dreger, Peter and Eisenbach, Christoph and Kunz, Christina and Benner, Axel and Buchholz, U. and Aichinger, E. and Frank, Uwe and Heeg, Klaus and Ho, Anthony Dick and Egerer, Gerlinde}, title={Risk factors and containment of respiratory syncytial virus outbreak in a hematology and transplant unit}, year={2013}, pages={1548-1553}, language={eng}, issn={1476-5365}, volume={48}, number={12 vom: Nov.}, note={Gesehen am 15.12.2021}, journal={Bone marrow transplantation}, doi={10.1038/bmt.2013.94}, } @book{UBHD-67828529, author={G{\"u}ndogdu, Mehtap and Metzdorf, Daniela and Hildebrand, Dagmar and Heeg, Klaus and Hieke-Kubatzky, Katharina}, title={The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression}, publisher={Biomed Central}, address={London}, year={2010}, pages={Online-Ressource}, language={eng}, note={Aus: Molecular cancer, 9 (2010), Nr. 225. pp. 1-13. ISSN 1476-4598}, url={http://www.ub.uni-heidelberg.de/archiv/18658}, library={UB}, } @book{UBHD-69263034, author={Heeg, Klaus}, title={Die Beeinflussung der T-Zellreaktivit{\"a}t durch Interleukin 2 in vivo und in vitro}, year={1983}, pages={III, 161 S.}, language={ger}, school={Mainz, Univ., Diss., 1983}, } @book{UBHD-67378573, author={Heeg, Klaus}, title={Funktionsvielfalt von klonal sich entwickelnden murinen T-Zellsubpopulationen}, year={1988}, pages={123 Bl.}, language={ger}, school={Ulm, Univ., Habil.-Schr., 1988}, } @book{UBHD-69263006, author={Heeg, Klaus}, title={Schlussbericht zum F{\"o}rdervorhaben "Pathophysiologie bakterieller Exotoxine (Superantigene) im Tiermodell des septischen Schocks"}, subtitle={[Abschlussdatum des Vorhabens: 30.04.2001]}, publisher={Inst. f. Med. Mikrobiologie, Immunologie u. Hygiene, Techn. Univ.}, address={M{\"u}nchen}, year={1998}, pages={8, [4] Bl.}, language={ger}, note={F{\"o}rderkennzeichen BMBF 01 KI 9472 1. - Engl. Zsfassung u.d.T.: Pathophysiology of bacterial exotoxins (superantigens) on animal model of septic shock}, } @book{UBHD-69263001, author={Heeg, Klaus}, organization={Technische Universit{\"a}t M{\"u}nchen / Institut f{\"u}r Medizinische Mikrobiologie, Immunologie und Hygiene}, title={Verbund Septischer Schock: Pathophysiologie bakterieller Exotoxine (Superantigene) im Tiermodell des septischen Schocks}, subtitle={Vorhaben ; Laufzeit: 1.5.1995 bis 30.4.1998 ; Abschlußbericht}, address={M{\"u}nchen}, year={1998}, pages={8, [4] Bl}, language={ger}, note={F{\"o}rderkennzeichen BMBF 01 KI 9472/1. - Engl. Titel der Zusammenfassung: Pathophysiology of bacterial exotoxins (superantigens) on animal model of septic shock}, } @article{UBHD-68791931, author={Heyder, Petra and Bekeredjian-Ding, Isabelle and Parčina, Marijo and Blank, Norbert and Ho, Anthony Dick and Herrmann, Martin and Lorenz, Hanns-Martin and Heeg, Klaus and Schiller, Martin}, title={Purified apoptotic bodies stimulate plasmacytoid dendritic cells to produce IFN-alpha}, year={2007}, pages={331-332}, language={eng}, issn={1607-842X}, volume={40}, number={4}, note={Elektronische Reproduktion der Druckausgabe ; Gesehen am 20.10.2021}, journal={Autoimmunity}, doi={10.1080/08916930701356515}, } @article{UBHD-68905390, author={Hildebrand, Dagmar and Nurjadi, Dennis and Hoan, Nghiem Xuan and Linh, Mai Thanh Hai and Sang, Vu Viet and Bang, Mai Hong and Pallerla, Srinivas Reddy and Kremsner, Peter and Heeg, Klaus and Song, Le Huu and Velavan, Thirumalaisamy P.}, title={Association between soluble Notch ligand delta-like ligand 1 and bleeding complications in patients with dengue fever infection}, year={2022}, pages={476-480}, language={eng}, issn={1537-6613}, volume={225}, number={3}, note={Published online August 10, 2021 ; Gesehen am 08.04.2022}, journal={The journal of infectious diseases}, doi={10.1093/infdis/jiab404}, } @article{UBHD-68936110, author={Hildebrand, Dagmar and B{\"o}hringer, Jana and K{\"o}rner, Eva-Maria and Chiriac, Ute and F{\"o}rmer, Sandra and S{\"a}hr, Aline and Hoppe-Tichy, Torsten and Heeg, Klaus and Nurjadi, Dennis}, title={Cefiderocol protects against cytokine- and endotoxin-induced disruption of vascular endothelial cell integrity in an in vitro experimental model}, year={2022}, pages={1-6}, language={eng}, issn={2079-6382}, volume={11}, note={Gesehen am 30.06.2022}, journal={Antibiotics}, doi={10.3390/antibiotics11050581}, } @article{UBHD-67811627, author={Hildebrand, Dagmar and Bode, Konrad A. and Rieß, David and Cerny, Daniela and Miethke, Thomas and Heeg, Klaus and Hieke-Kubatzky, Katharina}, title={Granzyme A produces bioactive IL-1 beta through a nonapoptotic inflammasome-independent pathway}, year={2014}, pages={910-917}, language={eng}, issn={2211-1247}, volume={9}, number={3}, note={Gesehen am: 30.04.2015}, journal={Cell reports}, doi={10.1016/j.celrep.2014.10.003}, } @article{UBHD-68437102, author={Hildebrand, Dagmar and Decker, Sebastian and Koch, Christian and Schmitt, Felix and Ruhrmann, Sophie and Schneck, Emmanuel and Sander, Michael and Weigand, Markus A. and Brenner, Thorsten and Heeg, Klaus and Uhle, Florian}, title={Host-derived delta-like canonical notch ligand 1 as a novel diagnostic biomarker for bacterial sepsis}, subtitle={results from a combinational secondary analysis}, year={2019}, language={eng}, issn={2235-2988}, volume={9(2019) Artikel-Nummer 267}, number={9 Seiten}, note={Gesehen am 09.10.2019}, journal={Frontiers in Cellular and Infection Microbiology}, doi={10.3389/fcimb.2019.00267}, url={https://doi.org/10.3389/fcimb.2019.00267}, library={UB}, } @article{UBHD-68290102, author={Hildebrand, Dagmar and Eberle, Mariel-Esther and W{\"o}lfle, Sabine J. and Falk, Franziska and Sahin, Delal and S{\"a}hr, Aline and Bode, Konrad A. and Heeg, Klaus}, title={Hsa-miR-99b/let-7e/miR-125a cluster regulates pathogen recognition receptor-stimulated suppressive antigen-presenting cells}, year={2018}, language={eng}, issn={1664-3224}, volume={9(2018) Artikel-Nummer 1224}, number={12 Seiten}, note={Published: 18 June 2018 ; Gesehen am 30.07.2018}, journal={Frontiers in immunology}, doi={10.3389/fimmu.2018.01224}, url={http://dx.doi.org/10.3389/fimmu.2018.01224}, library={UB}, } @article{UBHD-68284942, author={Hildebrand, Dagmar and Uhle, Florian and Sahin, Delal and Krauser, Ute and Weigand, Markus A. and Heeg, Klaus}, title={The interplay of Notch signaling and STAT3 in TLR-activated human primary monocytes}, year={2018}, language={eng}, issn={2235-2988}, volume={8(2018) Artikel-Nummer 241}, number={12 Seiten}, note={Gesehen am 12.07.2018}, journal={Frontiers in Cellular and Infection Microbiology}, doi={10.3389/fcimb.2018.00241}, url={http://dx.doi.org/10.3389/fcimb.2018.00241}, library={UB}, } @article{UBHD-68019347, author={Hildebrand, Dagmar and Heeg, Klaus and Hieke-Kubatzky, Katharina}, title={Pasteurella multocida toxin manipulatesT cell differentiation}, year={2015}, language={eng}, issn={1664-302X}, volume={6(2015) Artikel-Nummer 1273}, number={13 Seiten}, note={Gesehen am 18.08.2016}, journal={Frontiers in microbiology}, doi={10.3389/fmicb.2015.01273}, } @article{UBHD-68964342, author={Hildebrand, Dagmar and Heeg, Klaus and Hieke-Kubatzky, Katharina}, title={Pasteurella multocida toxin-stimulated osteoclast differentiation is B cell dependent}, year={2011}, pages={220-228}, language={eng}, issn={1098-5522}, volume={79}, number={1 vom: Dez.}, note={Gesehen am 14.09.2022}, journal={Infection and immunity}, doi={10.1128/IAI.00565-10}, } @article{UBHD-68421466, author={Hildebrand, Dagmar and Heeg, Klaus}, title={Silencing SOCS1 via Liposome-Packed siRNA Sustains TLR4-Ligand Adjuvant}, year={2019}, pages={12 S.}, language={eng}, issn={1664-3224}, volume={10(2019) Artikel-Nummer 1279}, number={12 Seiten}, note={Gesehen am 16.08.2019}, journal={Frontiers in immunology}, doi={10.3389/fimmu.2019.01279}, url={https://doi.org/10.3389/fimmu.2019.01279}, library={UB}, } @article{UBHD-68740583, author={Hilmi, Dina and Parčina, Marijo and Bode, Konrad A. and Ostrop, Jenny and Schuett, Sabine and Heeg, Klaus and Ziebuhr, Wilma and Sommerburg, Olaf and Bekeredjian-Ding, Isabelle}, title={Functional variation reflects intra-strain diversity of Staphylococcus aureus small colony variants in the host-pathogen interaction}, year={2013}, pages={61-69}, language={eng}, issn={1618-0607}, volume={303}, number={2}, note={Gesehen am 25.05.2021}, journal={International journal of medical microbiology}, doi={10.1016/j.ijmm.2012.12.008}, } @article{UBHD-67984517, author={Hilmi, Dina and Parčina, Marijo and Heeg, Klaus and Bekeredjian-Ding, Isabelle}, title={Heterogeneity of host TLR2 stimulation by staphylocoocus aureus isolates}, year={2014}, pages={11 S.}, language={eng}, issn={1932-6203}, volume={9(2014}, note={Gesehen am 14.05.2016}, journal={PLOS ONE}, doi={10.1371/journal.pone.0096416}, } @article{UBHD-68743956, author={Klein, Sabrina and Boutin, Sébastien and Sp{\"a}th, Isabel and Kimmich, Christoph and Brandt, Juliane and M{\"u}ller-Tidow, Carsten and Heeg, Klaus and Nurjadi, Dennis}, title={Acquisition and transmission of carbapenemase-producing (blaKPC-2) enterobacter cloacae in a highly frequented outpatient clinic}, year={2021}, pages={e158-e161}, language={eng}, issn={1537-6591}, volume={72}, number={5}, note={Published: 19 November 2020 ; Gesehen am 02.06.2021 ; Im Titel ist KPC-2 tiefgestellt}, journal={Clinical infectious diseases}, doi={10.1093/cid/ciaa1734}, } @article{UBHD-68917153, author={Klein, Sabrina and Morath, Benedict and Weitz, Daniel and Schweizer, Patrick Alexander and S{\"a}hr, Aline and Heeg, Klaus and Boutin, Sébastien and Nurjadi, Dennis}, title={Comparative genomic reveals clonal heterogeneity in persistent staphylococcus aureus infection}, year={2022}, pages={1-10}, language={eng}, issn={2235-2988}, volume={12}, number={Artikel-ID 817841}, note={Gesehen am 11.05.2022}, journal={Frontiers in Cellular and Infection Microbiology}, doi={10.3389/fcimb.2022.817841}, url={https://doi.org/10.3389/fcimb.2022.817841}, library={UB}, } @article{UBHD-68653854, author={Klein, Sabrina and Hannesen, Julius and Zanger, Philipp and Heeg, Klaus and Boutin, Sébastien and Nurjadi, Dennis}, title={Entry of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus into the hospital}, subtitle={prevalence and population structure in Heidelberg, Germany 2015-2018}, year={2020}, pages={7 S.}, language={eng}, issn={2045-2322}, volume={10(2020) Artikel-Nummer 13243}, number={7 Seiten}, note={Gesehen am 03.11.2020}, journal={Scientific reports}, doi={10.1038/s41598-020-70112-z}, url={https://doi.org/10.1038/s41598-020-70112-z}, library={UB}, } @article{UBHD-68961692, author={Klein, Sabrina and Boutin, Sébastien and Heeg, Klaus and Zanger, Philipp and Nurjadi, Dennis}, title={Genomic structure of ST8-t008 USA300 and USA300-LV MRSA in the Rhine-Neckar Region, Germany, 2012-2018}, year={2021}, pages={1-5}, language={eng}, issn={1872-7913}, volume={57}, note={Gesehen am 07.09.2022}, journal={International journal of antimicrobial agents}, doi={10.1016/j.ijantimicag.2021.106312}, } @article{UBHD-68378406, author={Klein, Sabrina and Menz, Monja-Dorina and Zanger, Philipp and Heeg, Klaus and Nurjadi, Dennis}, title={Increase in the prevalence of Panton-Valentine leukocidin and clonal shift in community-onset methicillin-resistant Staphylococcus aureus causing skin and soft-tissue infections in the Rhine-Neckar Region, Germany, 2012-2016}, year={2019}, pages={261-267}, language={eng}, issn={1872-7913}, volume={53}, number={3}, note={Available online 6 November 2018 ; Gesehen am 03.04.2019}, journal={International journal of antimicrobial agents}, doi={10.1016/j.ijantimicag.2018.10.026}, } @article{UBHD-68448200, author={Klein, Sabrina and Nurjadi, Dennis and Heeg, Klaus and Zimmermann, Stefan and Burckhardt, Irene}, title={Significant increase in cultivation of Gardnerella vaginalis, Alloscardovia omnicolens, Actinotignum schaalii, and Actinomyces spp. in urine samples with total laboratory automation}, year={2018}, pages={1305-1311}, language={eng}, issn={1435-4373}, volume={37}, number={7}, note={Gesehen am 30.10.2019}, journal={European journal of clinical microbiology & infectious diseases}, doi={10.1007/s10096-018-3250-6}, } @article{UBHD-68631437, author={Kocer, Kaan and Boutin, Sébastien and Dalpke, Alexander and Heeg, Klaus and Mutters, Nico T. and Nurjadi, Dennis}, title={Comparative genomic analysis reveals a high prevalence of inter-species in vivo transfer of carbapenem-resistance plasmids in patients with haematological malignancies}, year={2020}, pages={780.e1-780.e8}, language={eng}, issn={1469-0691}, volume={26}, number={6}, note={Available online 23 October 2019 ; Gesehen am 26.08.2020}, journal={Clinical microbiology and infection}, doi={10.1016/j.cmi.2019.10.014}, } @article{UBHD-68660386, author={Kocer, Kaan and Boutin, Sébastien and Probst, Katja and Heeg, Klaus and Nurjadi, Dennis}, title={Whole-genome sequencing disproves two suspected transmission events of blaNDM between Pseudomonas aeruginosa and Enterobacterales in hospitalized patients}, year={2020}, pages={372-375}, language={eng}, issn={1532-2939}, volume={106}, number={2}, note={Im Titel ist "NDM" tiefgestellt ; Gesehen am 12.11.2020}, journal={The journal of hospital infection}, doi={10.1016/j.jhin.2020.07.006}, } @article{UBHD-68871868, author={Kocer, Kaan and Klein, Sabrina and Hildebrand, Dagmar and Krall, Lars Johannes and Heeg, Klaus and Boutin, Sébastien and Nurjadi, Dennis}, title={Pitfalls in genotypic antimicrobial susceptibility testing caused by low expression of blaKPC in Escherichia coli}, year={2021}, pages={2795-2801}, language={eng}, issn={1460-2091}, volume={76}, number={11}, note={Gesehen am 28.01.2022}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkab267}, } @article{UBHD-68866163, author={Krall, Lars Johannes and Klein, Sabrina and Boutin, Sébastien and Wu, Chia Ching and S{\"a}hr, Aline and Stanifer, Megan and Boulant, Steeve and Heeg, Klaus and Nurjadi, Dennis and Hildebrand, Dagmar}, title={Invasiveness of escherichia coli is associated with an IncFII plasmid}, year={2021}, pages={1-10}, language={eng}, issn={2076-0817}, volume={10}, note={Gesehen am 13.01.2022}, journal={Pathogens}, doi={10.3390/pathogens10121645}, } @article{UBHD-68674879, author={Marshall, Anne and Ziegler, Saskia and F{\"o}rmer, Sandra and Rieker, Ralf Joachim and Heeg, Klaus and Bekeredjian-Ding, Isabelle}, title={Phosphorothioate-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for Toll-like receptor 9 in receptor revision}, year={2013}, pages={166-178}, language={eng}, issn={1365-2567}, volume={139}, number={2}, note={Gesehen am 18.12.2020}, journal={Immunology}, doi={10.1111/imm.12063}, } @article{UBHD-68881495, author={Moll, Maximilian and Reichel, Konrad and Nurjadi, Dennis and F{\"o}rmer, Sandra and Krall, Lars Johannes and Heeg, Klaus and Hildebrand, Dagmar}, title={Notch ligand delta-like 1 is associated with loss of vascular endothelial barrier function}, year={2021}, pages={1-9}, language={eng}, issn={1664-042X}, volume={12(2021) vom: 10. Dez.}, number={Artikel-ID 766713}, note={Gesehen am 22.02.2022}, journal={Frontiers in physiology}, doi={10.3389/fphys.2021.766713}, url={https://doi.org/10.3389/fphys.2021.766713}, library={UB}, } @article{UBHD-68300371, author={Mutters, Nico T. and Heeg, Klaus and Sp{\"a}th, Isabel and Henny, Nicole and G{\"u}nther, Frank}, title={Improvement of infection control management by routine molecular evaluation of pathogen clusters}, year={2017}, pages={82-87}, language={eng}, issn={1879-0070}, volume={88}, number={1}, note={Gesehen am 30.08.2018}, journal={Diagnostic microbiology and infectious disease}, doi={10.1016/j.diagmicrobio.2017.01.013}, } @article{UBHD-68799895, author={Mutters, Nico T. and Brooke, Russell John and Frank, Uwe and Heeg, Klaus}, title={Low risk of apparent transmission of vancomycin-resistant Enterococci from bacteraemic patients to hospitalized contacts}, year={2013}, pages={778-781}, language={eng}, issn={1527-3296}, volume={41}, number={9}, note={Gesehen am 16.11.2021}, journal={American journal of infection control}, doi={10.1016/j.ajic.2012.11.019}, } @article{UBHD-69233752, author={Ngo, Quang Vinh and Faass, Larissa and S{\"a}hr, Aline and Hildebrand, Dagmar and Eigenbrod, Tatjana and Heeg, Klaus and Nurjadi, Dennis}, title={Corrigendum: Inflammatory response against Staphylococcus aureus via intracellular sensing of nucleic acids in keratinocytes}, year={2024}, pages={1-2}, language={eng}, issn={1664-3224}, volume={15}, number={Artikel-ID 1330357}, note={Gesehen am 15.07.2024}, journal={Frontiers in immunology}, doi={10.3389/fimmu.2024.1330357}, } @article{UBHD-68901984, author={Ngo, Quang Vinh and Faass, Larissa and S{\"a}hr, Aline and Hildebrand, Dagmar and Eigenbrod, Tatjana and Heeg, Klaus and Nurjadi, Dennis}, title={Inflammatory response against staphylococcus aureus via intracellular sensing of nucleic acids in keratinocytes}, year={2022}, pages={1-12}, language={eng}, issn={1664-3224}, volume={13}, number={Artikel-ID 828626}, note={Gesehen am 31.03.2022}, journal={Frontiers in immunology}, doi={10.3389/fimmu.2022.828626}, url={https://doi.org/10.3389/fimmu.2022.828626}, library={UB}, } @article{UBHD-68286957, author={Nurjadi, Dennis and Boutin, Sébastien and Dalpke, Alexander and Heeg, Klaus and Zanger, Philipp}, title={Draft genome sequence of Staphylococcus aureus strain HD1410, isolated from a persistent nasal carrier}, year={2018}, language={eng}, issn={2169-8287}, volume={6(2018}, note={Gesehen am 19.07.2018}, journal={Genome announcements}, doi={10.1128/genomeA.00411-18}, url={http://dx.doi.org/10.1128/genomeA.00411-18}, library={UB}, } @article{UBHD-68688536, author={Nurjadi, Dennis and Heeg, Klaus and Boutin, Sébastien}, title={Integrative analysis of whole genome sequencing and phenotypic resistance toward prediction of trimethoprim-sulfamethoxazole resistance in staphylococcus aureus}, year={2021}, pages={7 S.}, language={eng}, issn={1664-302X}, volume={11(2021) Artikel-Nummer 607842}, number={7 Seiten}, note={Gesehen am 04.02.2021}, journal={Frontiers in microbiology}, doi={10.3389/fmicb.2020.607842}, url={https://doi.org/10.3389/fmicb.2020.607842}, library={UB}, } @article{UBHD-68961930, author={Nurjadi, Dennis and Klein, Sabrina and Hannesen, Julius and Heeg, Klaus and Boutin, Sébastien and Zanger, Philipp}, title={Molecular analysis of an increase in trimethoprim/sulfamethoxazole-resistant MRSA reveals multiple introductions into a tertiary care hospital, Germany 2012-19}, year={2022}, pages={38-48}, language={eng}, issn={1460-2091}, volume={77}, number={1 vom: Jan.}, note={Advance access publication 16 September 2021 ; Gesehen am 08.09.2022}, journal={The journal of antimicrobial chemotherapy}, doi={10.1093/jac/dkab341}, } @article{UBHD-69133630, author={Nurjadi, Dennis and Eichel, Vanessa and P{\"o}schl, Johannes and Gille, Christian and Kranig, Simon A. and Heeg, Klaus and Boutin, Sébastien}, title={Monocentric observational cohort study to investigate the transmission of third-generation cephalosporin-resistant Enterobacterales in a neonatal intensive care unit in Heidelberg, Germany}, year={2023}, pages={1-11}, language={eng}, issn={2165-0497}, volume={11}, note={Online ver{\"o}ffentlicht: 22. September 2023 ; Gesehen am 25.10.2023}, journal={Microbiology spectrum}, doi={10.1128/spectrum.02038-23}, } @article{UBHD-68575874, author={Nurjadi, Dennis and Last, Katharina and Klein, Sabrina and Boutin, Sébastien and Schmack, Bastian and M{\"u}ller, Florian and Heeg, Klaus and Ruhparwar, Arjang and Heininger, Alexandra and Zanger, Philipp}, title={Nasal colonization with Staphylococcus aureus is a risk factor for ventricular assist device infection in the first year after implantation}, subtitle={a prospective, single-centre, cohort study}, year={2020}, pages={511-518}, language={eng}, issn={1532-2742}, volume={80}, number={5}, note={Gesehen am 12.05.2020}, journal={Journal of infection}, doi={10.1016/j.jinf.2020.02.015}, } @article{UBHD-68917152, author={Nurjadi, Dennis and Kocer, Kaan and Chanthalangsy, Quan and Klein, Sabrina and Heeg, Klaus and Boutin, Sébastien}, title={New Delhi metallo-beta-lactamase facilitates the emergence of cefiderocol resistance in Enterobacter cloacae}, year={2022}, pages={1-11}, language={eng}, issn={1098-6596}, volume={66}, note={Gesehen am 11.05.2022}, journal={Antimicrobial agents and chemotherapy}, doi={10.1128/aac.02011-21}, } @article{UBHD-68862536, author={Nurjadi, Dennis and Chanthalangsy, Quan and Zizmann, Elfi and St{\"u}rmer, Vanessa S. and Moll, Maximilian and Klein, Sabrina and Boutin, Sébastien and Heeg, Klaus and Zanger, Philipp}, title={Phenotypic detection of hemin-inducible trimethoprim-sulfamethoxazole heteroresistance in staphylococcus aureus}, year={2021}, pages={1-10}, language={eng}, issn={2165-0497}, volume={9}, note={Gesehen am 04.01.2022}, journal={Microbiology spectrum}, doi={10.1128/Spectrum.01510-21}, } @article{UBHD-68593119, author={Nurjadi, Dennis and Kain, Marlon Shiva and Marcinek, Patrick and Gaile, Marika and Heeg, Klaus and Zanger, Philipp}, title={Ratio of T-helper type 1 (Th1) to Th17 cytokines in whole blood is associated with human β-defensin 3 expression in skin and persistent staphylococcus aureus nasal carriage}, year={2016}, pages={1744-1751}, language={eng}, issn={1537-6613}, volume={214}, number={11}, note={Gesehen am 26.06.2020}, journal={The journal of infectious diseases}, doi={10.1093/infdis/jiw440}, } @article{UBHD-68790143, author={Nurjadi, Dennis and Eichel, Vanessa and Tabatabai, Patrik and Klein, Sabrina and Last, Katharina and Mutters, Nico T. and P{\"o}schl, Johannes and Zanger, Philipp and Heeg, Klaus and Boutin, Sébastien}, title={Surveillance for colonization, transmission, and infection with methicillin-susceptible staphylococcus aureus in a neonatal intensive care unit}, year={2021}, pages={1-13}, language={eng}, issn={2574-3805}, volume={4}, note={Gesehen am 14.10.2021}, journal={JAMA network open}, doi={10.1001/jamanetworkopen.2021.24938}, url={https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2783982}, library={UB}, } @article{UBHD-68557913, author={Nurjadi, Dennis and Heeg, Klaus and Weber, A. N. R. and Zanger, Philipp}, title={Toll-like receptor 9 (TLR-9) promotor polymorphisms and gene expression are associated with persistent Staphylococcus aureus nasal carriage}, year={2018}, pages={1210.e7-1210.e12}, language={eng}, issn={1469-0691}, volume={24}, number={11}, note={Gesehen am 25.03.2020}, journal={Clinical microbiology and infection}, doi={10.1016/j.cmi.2018.02.014}, } @article{UBHD-68275750, author={Nurjadi, Dennis and Klein, Sabrina and Zimmermann, Stefan and Heeg, Klaus and Zanger, Philipp}, title={Transmission of ST8-USA300 Latin American Variant methicillin-resistant Staphylococcus aureus on a neonatal intensive care unit}, subtitle={recurrent skin and soft- tissue infections as a marker for epidemic community-associated-MRSA colonization}, year={2017}, pages={883-885}, language={eng}, issn={1559-6834}, volume={38}, number={7}, note={Published online: 18 May 2017 ; Gesehen am 29.06.2018}, journal={Infection control and hospital epidemiology}, doi={10.1017/ice.2017.88}, } @article{UBHD-68254806, author={Nurjadi, Dennis and Heeg, Klaus and Zanger, Philipp}, title={A trial of antibiotics for smaller skin abscesses}, year={2017}, language={eng}, issn={1533-4406}, volume={377(2017}, note={Das Dokument enth{\"a}lt 4 einzelne Briefe aus verschiedenen Einrichtungen. Hier ist nur der Beitrag aus der Universit{\"a}tsklinik Heidelberg erfasst. ; Gesehen am 25.05.2018}, journal={The New England journal of medicine}, doi={10.1056/NEJMc1711124}, } @article{UBHD-68810935, author={Over, Benjamin and Ziegler, Saskia and F{\"o}rmer, Sandra and Weber, Alexander N.R. and Bode, Konrad A. and Heeg, Klaus and Bekeredjian-Ding, Isabelle}, title={IRAK4 turns IL-10+ phospho-FOXO+ monocytes into pro-inflammatory cells by suppression of protein kinase B}, year={2013}, pages={1630-1642}, language={eng}, issn={1521-4141}, volume={43}, number={6}, note={Gesehen am 09.12.2021 ; Im Titel sind die "+"-Zeichen jeweils hochgestellt}, journal={European journal of immunology}, doi={10.1002/eji.201243217}, } @article{UBHD-68845828, author={Parčina, Marijo and Miranda-Garcia, Maria Auxiliadora and Durlanik, Sibel and Ziegler, Saskia and Over, Benjamin and Georg, Philipp and F{\"o}rmer, Sandra and Ammann, Sandra and Hilmi, Dina and Weber, Klaus-Josef and Schiller, Martin and Heeg, Klaus and Schneider-Brachert, Wulf and G{\"o}tz, Friedrich and Bekeredjian-Ding, Isabelle}, title={Pathogen-triggered activation of plasmacytoid dendritic cells induces IL-10-producing B cells in response to Staphylococcus aureus}, year={2013}, pages={1591-1602}, language={eng}, issn={1550-6606}, volume={190}, number={4}, note={Gesehen am 20.12.2021}, journal={The journal of immunology}, doi={10.4049/jimmunol.1201222}, } @article{UBHD-68803218, author={Probst, Katja and Boutin, Sébastien and Sp{\"a}th, Isabel and Scherrer, Martin and Henny, Nicole and Sahin, Delal and Heininger, Alexandra and Heeg, Klaus and Nurjadi, Dennis}, title={Direct-PCR from rectal swabs and environmental reservoirs}, subtitle={a fast and efficient alternative to detect blaOXA-48 carbapenemase genes in an Enterobacter cloacae outbreak setting}, year={2022}, pages={1-5}, language={eng}, issn={1096-0953}, volume={203(2022) vom: Jan.}, number={Artikel-ID 111808}, note={Available online 31 July 2021 ; Im Titel Zusatz zum Titel ist "OXA-48" tiefgestellt ; Gesehen am 18.11.2021}, journal={Environmental research}, doi={10.1016/j.envres.2021.111808}, } @article{UBHD-68764346, author={Probst, Katja and Boutin, Sébastien and Bandilla, Michael and Heeg, Klaus and Dalpke, Alexander}, title={Fast and automated detection of common carbapenemase genes using multiplex real-time PCR on the BD MAXTM system}, year={2021}, pages={1-7}, language={eng}, issn={1872-8359}, volume={185(2021) vom: Juni}, number={Artikel-ID 106224}, note={Gesehen am 28.07.2021 ; Im Titel ist "TM" hochgestellt}, journal={Journal of microbiological methods}, doi={10.1016/j.mimet.2021.106224}, } @article{UBHD-68767427, author={Probst, Katja and Nurjadi, Dennis and Heeg, Klaus and Frede, Anne-Marie and Dalpke, Alexander and Boutin, Sébastien}, title={Molecular detection of carbapenemases in enterobacterales}, subtitle={a comparison of real-time multiplex PCR and whole-genome sequencing}, year={2021}, pages={1-8}, language={eng}, issn={2079-6382}, volume={10}, note={Gesehen am 05.08.2021}, journal={Antibiotics}, doi={10.3390/antibiotics10060726}, } @article{UBHD-68379677, author={Rollenske, Tim and Lasitschka, Felix and Saeedi, Mohammed al and Schr{\"o}der-Braunstein, Jutta and Hoffmann, Peter and Klein, Sabrina and Heeg, Klaus}, title={Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen}, year={2018}, pages={617-624}, language={eng}, issn={1529-2916}, volume={19}, number={6}, note={Gesehen am 10.04.2019}, journal={Nature immunology}, doi={10.1038/s41590-018-0106-2}, } @article{UBHD-68036209, author={S{\"a}hr, Aline and F{\"o}rmer, Sandra and Hildebrand, Dagmar and Heeg, Klaus}, title={T-cell activation or tolerization}, subtitle={the Yin and Yang of bacterial superantigens}, year={2015}, language={eng}, issn={1664-302X}, volume={6(2015) Artikel-Nummer 1153}, number={12 Seiten}, note={Gesehen am 06.10.2016}, journal={Frontiers in microbiology}, doi={10.3389/fmicb.2015.01153}, } @article{UBHD-68249258, author={Schiller, Martin and Parčina, Marijo and Heyder, Petra and F{\"o}rmer, Sandra and Ostrop, Jenny and Leo, Albrecht and Heeg, Klaus and Lorenz, Hanns-Martin and Bekeredjian-Ding, Isabelle}, title={Induction of type I IFN is a physiological immune reaction to apoptotic cell-derived membrane microparticles}, year={2012}, pages={1747-1756}, language={eng}, issn={1550-6606}, volume={189}, number={4}, note={Gesehen am 04.05.2018}, journal={The journal of immunology}, doi={10.4049/jimmunol.1100631}, } @book{UBHD-68741479, organization={Zentrum f{\"u}r Infektiologie / Bereich Medizinische Mikrobiologie und Hygiene}, title={Schlussbericht f{\"u}r das BMBF Forschungsvorhaben: Halbleiterbasierte molekulardiagnostische Multiplex-Plattform f{\"u}r die Bestimmung (multi-)resistenter Erreger am Point-of-Care}, subtitle={Teilvorhaben: MRGN Assayentwicklung : Laufzeit des Vorhabens: 01.09.2017 bis 30.11.2019}, publisher={Universit{\"a}tsklinikum Heidelberg}, address={Heidelberg}, year={2019}, pages={1 Online-Ressource (20 Seiten, 1,32 MB)}, language={ger}, note={F{\"o}rderkennzeichen BMBF 16GW0163 ; Verbundnummer 01180855 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, doi={10.2314/KXP:1735742406}, keywords={Gram-negative Bakterien / Multidrug-Resistenz / Real time quantitative PCR / Bedside-Methode / Lab on a Chip}, } @book{UBHD-68741477, organization={Zentrum f{\"u}r Infektiologie / Bereich Medizinische Mikrobiologie und Hygiene}, title={Schlussbericht f{\"u}r das BMBF Forschungsvorhaben: Halbleiterbasierte molekulardiagnostische Multiplex-Plattform f{\"u}r die Bestimmung (multi-)resistenter Erreger am Point-of-Care}, subtitle={Teilvorhaben: MRGN Assayentwicklung : Laufzeit des Vorhabens: 01.09.2017 bis 30.11.2019}, publisher={Universit{\"a}tsklinikum Heidelberg}, address={Heidelberg}, year={2020}, pages={1 ungez{\"a}hltes Blatt, 17 Bl{\"a}tter, 2 ungez{\"a}hlte Bl{\"a}tter}, language={ger}, note={F{\"o}rderkennzeichen BMBF 16GW0163 ; Verbundnummer 01180855 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource k{\"o}nnen nicht ausgeschlossen werden}, keywords={Gram-negative Bakterien / Multidrug-Resistenz / Real time quantitative PCR / Bedside-Methode / Lab on a Chip}, } @article{UBHD-68988717, author={Sommerer, Claudia and Schroter, Iris and Gruneberg, Katrin and Schindler, Daniela and Behnisch, Rouven and Morath, Christian and Renders, Lutz and Heemann, Uwe and Schnitzler, Paul and Melk, Anette and Della Penna, Andrea and Nadalin, Silvio and Heeg, Klaus and Meuer, Stefan and Zeier, Martin and Giese, Thomas}, title={Incidences of Infectious Events in a Renal Transplant Cohort of the German Center of Infectious Diseases (DZIF)}, year={2022}, pages={1-11}, language={eng}, issn={2328-8957}, volume={9}, note={Gesehen am 24.11.2022}, journal={Open Forum Infectious Diseases}, doi={10.1093/ofid/ofac243}, } @article{UBHD-68013013, author={Stammler, Dominik and Eigenbrod, Tatjana and Heeg, Klaus and Dalpke, Alexander and Bode, Konrad A.}, title={Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1β via a caspase-1–independent mechanism}, year={2015}, pages={5421-5431}, language={eng}, issn={1550-6606}, volume={195}, number={11}, note={Gesehen am 01.08.2016}, journal={The journal of immunology}, doi={10.4049/jimmunol.1501195}, } @article{UBHD-68121130, author={Ulrich, Kerstin and W{\"o}lfle, Sabine J. and Mayer, Anja and Heeg, Klaus and Braunbeck, Thomas and Erdinger, Lothar}, title={Extractable organic matter of Standard Reference Material 1649a influences immunological response induced by pathogen-associated molecular patterns}, year={2010}, pages={1257-1267}, language={eng}, issn={1614-7499}, volume={17}, number={6}, note={Gesehen am 19.05.2017}, journal={Environmental science and pollution research}, doi={10.1007/s11356-010-0305-3}, } @article{UBHD-68862849, author={Wachinger, Jonas and Olaru, Ioana D. and Horner, Susanne and Schnitzler, Paul and Heeg, Klaus and Denkinger, Claudia M.}, title={The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons}, year={2021}, pages={1700.e1-1700.e3}, language={eng}, issn={1469-0691}, volume={27}, number={11}, note={Gesehen am 05.01.2022}, journal={Clinical microbiology and infection}, doi={10.1016/j.cmi.2021.07.020}, } @incollection{UBHD-69263021, author={Wagner, Hermann and Heeg, Klaus and Lipford, Grayson B.}, title={Bacterial DNA}, subtitle={virulence factor or "natural adjuvants" for the immune system}, year={1999}, pages={163-169}, language={eng}, isbn={3-335-00618-6 and 978-3-335-00618-3}, booktitle={Problems of relevant infectious diseases}, } @article{UBHD-69194439, author={Welker, Sybille and Boutin, Sébastien and Miethke, Thomas and Heeg, Klaus and Nurjadi, Dennis}, title={Emergence of carbapenem-resistant ST131 Escherichia coli carrying blaOXA-244 in Germany, 2019 to 2020}, year={2020}, pages={1-8}, language={eng}, issn={1560-7917}, volume={25}, note={Im Titel ist "OXA-244 " tiefgestellt ; Gesehen am 22.03.2024}, journal={Eurosurveillance}, doi={10.2807/1560-7917.ES.2020.25.46.2001815}, } @article{UBHD-68135529, author={Wiedenmann, Tanja and Erhardt, Stefanie and Cerny, Daniela and Hildebrand, Dagmar and Klein, Sabrina and Heeg, Klaus and Hieke-Kubatzky, Katharina}, title={Erythropoietin acts as an anti-inflammatory signal on murine mast cells}, year={2015}, pages={68-76}, language={eng}, issn={1872-9142}, volume={65}, number={1}, note={Gesehen am 07.07.2017}, journal={Molecular immunology}, doi={10.1016/j.molimm.2015.01.011}, } @article{UBHD-68992681, author={W{\"o}lfle, Sabine J. and Strebovsky, Julia and Bartz, Holger and S{\"a}hr, Aline and Arnold, Caroline and Kaiser, Claus and Dalpke, Alexander and Heeg, Klaus}, title={PD-L1 expression on tolerogenic APCs is controlled by STAT-3}, year={2011}, pages={413-424}, language={eng}, issn={1521-4141}, volume={41}, number={2}, note={First published: 08 December 2010 ; Gesehen am 05.12.2022}, journal={European journal of immunology}, doi={10.1002/eji.201040979}, } @article{UBHD-68764347, author={Ziegler, Saskia and Heeg, Klaus}, title={Bifunctional oligodeoxynucleotide/antagomiR constructs}, subtitle={Evaluation of a new tool for MicroRNA silencing}, year={2013}, pages={427-434}, language={eng}, issn={2159-3345}, volume={23}, number={6}, note={Gesehen am 28.07.2021}, journal={Nucleic acid therapeutics}, doi={10.1089/nat.2013.0447}, } @article{UBHD-67908804, author={Ziegler, Saskia and Gartner, Katrin and Scheuermann, Uwe and Z{\"o}ller, Tanja and Over, Benjamin and F{\"o}rmer, Sandra and Heeg, Klaus and Bekeredjian-Ding, Isabelle}, title={Ca2+- related signaling events influence TLR9-induced IL-10 secretion in human B cells}, year={2014}, pages={1285-1298}, language={eng}, issn={1521-4141}, volume={44}, number={5}, note={Gesehen am 27.11.2015}, journal={European journal of immunology}, doi={10.1002/eji.201343994}, }