@article{UBHD-68308807, author={Balß, J{\"o}rg and Pusch, Stefan and Herold-Mende, Christel and Kr{\"a}mer, Alwin and Langhans, Claus-Dieter and Okun, J{\"u}rgen G. and Deimling, Andreas von}, title={Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate}, year={2012}, pages={883-891}, language={eng}, issn={1432-0533}, volume={124}, number={6}, note={Gesehen am 25.09.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-012-1060-y}, } @article{UBHD-68621767, author={Balß, J{\"o}rg and Bochtler, Tilmann and Okun, J{\"u}rgen G. and Pusch, Stefan and Ho, Anthony Dick and Deimling, Andreas von and Kr{\"a}mer, Alwin and Heilig, Christoph E.}, title={Pretreatment d -2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia}, year={2016}, pages={782-788}, language={eng}, issn={1476-5551}, volume={30}, number={4}, note={Published: 19 November 2015 ; Gesehen am 29.07.2020}, journal={Leukemia}, doi={10.1038/leu.2015.317}, } @article{UBHD-68383686, author={Berberich, Anne and Keßler, Tobias and Pusch, Stefan and Sahm, Felix and Schmitt, Lara-Marie and Fischer, Manuel and Lemke, Dieter and Breckwoldt, Michael O. and Deimling, Andreas von and Bendszus, Martin and Platten, Michael and Wick, Wolfgang}, title={Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib}, year={2019}, pages={253-265}, language={eng}, issn={1557-3265}, volume={25}, number={1}, note={Gesehen am 30.04.2019 ; Published online first October 1, 2018}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-18-1580}, } @article{UBHD-68636683, author={Birner, Peter and Pusch, Stefan and Christov, Christo and Mihaylova, Stiliana and Toumangelova‐Uzeir, Kalina and Natchev, Sevdalin and Schoppmann, Sebastian F. and Tchorbanov, Andrey and Streubel, Berthold and T{\"u}ttenberg, Jochen and Guentchev, Marin}, title={Mutant IDH1 inhibits PI3K/Akt signaling in human glioma}, year={2014}, pages={2440-2447}, language={eng}, issn={1097-0142}, volume={120}, number={16}, note={Gesehen am 11.09.2020}, journal={Cancer}, doi={10.1002/cncr.28732}, } @article{UBHD-68927229, author={Brehmer, Stefanie and Pusch, Stefan and Schmieder, Kirsten and Deimling, Andreas von and Hartmann, Christian}, title={Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations}, year={2011}, pages={330-332}, language={eng}, issn={1365-2990}, volume={37}, number={3}, note={Published online article accepted on 17 August 2010 ; Gesehen am 03.06.2022}, journal={Neuropathology & applied neurobiology}, doi={10.1111/j.1365-2990.2010.01114.x}, } @article{UBHD-68341774, author={Buhl, Juliane and Selt, Florian and Hielscher, Thomas and Ecker, Jonas and Sahm, Felix and Ridinger, Johannes and Usta, Diren and Wefers, Annika K. and Remke, Marc and Pusch, Stefan and Oehme, Ina and Tilburg, Cornelis M. van and Kool, Marcel and Deimling, Andreas von and Herold-Mende, Christel and Korshunov, Andrey and Pfister, Stefan and Jones, David T. W. and Witt, Olaf and Milde, Till}, title={The senescence-associated secretory phenotype mediates oncogene-induced senescence in pediatric pilocytic astrocytoma}, year={2019}, pages={1851-1866}, language={eng}, issn={1557-3265}, volume={25}, number={6}, note={Published first: December 7, 2018 ; Gesehen am 18.12.2018}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-18-1965}, } @article{UBHD-67939437, author={Bunse, Lukas and Bunse, Theresa and Sahm, Felix and Pusch, Stefan and Oezen, Iris and Deimling, Andreas von and Wick, Wolfgang and Platten, Michael}, title={In situ proximity ligation assay to evaluate presentation of a mutated CD4 epitope in human glioma tissue}, year={2014}, pages={1 S.}, language={eng}, issn={1872-8421}, volume={275(2014}, note={Gesehen am 10.02.2016}, journal={Journal of neuroimmunology}, doi={10.1016/j.jneuroim.2014.08.096}, } @article{UBHD-67780854, author={Bunse, Lukas and Winkler, Frank and Herold-Mende, Christel and Deimling, Andreas von and Wick, Wolfgang and Platten, Michael and Bunse, Theresa and Sahm, Felix and Pusch, Stefan and Oezen, Iris and Rauschenbach, Katharina and Osswald, Matthias and Capper, David and Wiestler, Benedikt}, title={Proximity ligation assay evaluates IDH1 R132H presentation in gliomas}, year={2015}, pages={593-606}, language={eng}, issn={1558-8238}, volume={125}, number={2}, note={Gesehen am 27.02.2015}, journal={The journal of clinical investigation}, doi={10.1172/JCI77780}, } @article{UBHD-68284488, author={Bunse, Lukas and Pusch, Stefan and Bunse, Theresa and Sahm, Felix and Sonner, Jana K. and Deumelandt, Katrin and Uhlig, Stefanie and Keßler, Tobias and Breckwoldt, Michael O. and Meyer, Jochen and Habel, Antje and Poschet, Gernot and Ratliff, Miriam and Schrimpf, Daniel and Okun, J{\"u}rgen G. and Herold-Mende, Christel and Bieback, Karen and H{\"a}nggi, Daniel and Deimling, Andreas von and Wick, Wolfgang and Platten, Michael}, title={Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate}, year={2018}, pages={1192-1203}, language={eng}, issn={1546-170X}, volume={24}, note={Gesehen am 11.07.2018}, journal={Nature medicine}, doi={10.1038/s41591-018-0095-6}, } @article{UBHD-67940169, author={Bunse, Theresa and Bunse, Lukas and Pusch, Stefan and Sahm, Felix and Deimling, Andreas von and Wick, Wolfgang and Platten, Michael}, title={Mutant IDH1R132H bears a mutation-specific CD4 T cell epitope suitable for vaccination of human CNS tumors}, year={2014}, pages={1 S.}, language={eng}, issn={1872-8421}, volume={275(2014}, note={Gesehen am 11.02.2016}, journal={Journal of neuroimmunology}, doi={10.1016/j.jneuroim.2014.08.104}, } @article{UBHD-68935128, author={Capper, David and Preusser, Matthias and Habel, Antje and Sahm, Felix and Ackermann, Ulrike and Schindler, Genevieve and Pusch, Stefan and Mechtersheimer, Gunhild and Zentgraf, Hanswalter and Deimling, Andreas von}, title={Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody}, year={2011}, pages={11-19}, language={eng}, issn={1432-0533}, volume={122}, note={Gesehen am 28.06.2022}, journal={Acta neuropathologica}, doi={10.1007/s00401-011-0841-z}, } @article{UBHD-67243900, author={Capper, David and Preusser, Matthias and Habel, Antje and Sahm, Felix and Ackermann, Ulrike and Schindler, Genevieve and Pusch, Stefan and Mechtersheimer, Gunhild and Zentgraf, Hanswalter and Deimling, Andreas von}, title={Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody}, year={2011}, pages={11-19}, language={eng}, issn={0001-6322}, volume={122}, journal={Acta neuropathologica}, } @article{UBHD-68244139, author={Capper, David and Pusch, Stefan and Meyer, Jochen and Habel, Antje and Deimling, Andreas von and Preusser, Matthias}, title={Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases}, year={2012}, pages={223-233}, language={eng}, issn={1432-0533}, volume={123}, number={2}, note={Gesehen am 18.04.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-011-0887-y}, } @article{UBHD-68124395, author={Chaturvedi, Anuhar and Pusch, Stefan and Stichel, Damian and Bochtler, Tilmann and Ho, Anthony Dick and Deimling, Andreas von and Rippe, Karsten and Kr{\"a}mer, Alwin}, title={Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo}, year={2017}, pages={2020-2028}, language={eng}, issn={1476-5551}, volume={31}, number={10}, note={Gesehen am 15.11.2017}, journal={Leukemia}, doi={10.1038/leu.2017.46}, } @article{UBHD-68432585, author={Christians, Arne and Poisel, Eric and Deimling, Andreas von and Pusch, Stefan}, title={Characterization of the epithelial membrane protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation}, year={2019}, pages={461-473}, language={eng}, issn={1097-0215}, volume={145}, number={2}, note={Gesehen am 24.09.2019}, journal={International journal of cancer}, doi={10.1002/ijc.32107}, } @article{UBHD-68394393, author={Dao Trong, Huy Philip and R{\"o}sch, Saskia and Mairb{\"a}url, Heimo and Pusch, Stefan and Unterberg, Andreas and Herold-Mende, Christel and Warta, Rolf}, title={Identification of a prognostic hypoxia-associated gene set in IDH-mutant glioma}, year={2018}, pages={14 S.}, language={eng}, issn={1422-0067 and 1661-6596}, volume={19(2108}, note={Gesehen am 31.05.2019}, journal={International journal of molecular sciences}, doi={10.3390/ijms19102903}, } @article{UBHD-68631421, author={Dao Trong, Huy Philip and Jungwirth, Gerhard and Yu, Tao and Pusch, Stefan and Unterberg, Andreas and Herold-Mende, Christel and Warta, Rolf}, title={Large-scale drug screening in patient-derived IDHmut glioma stem cells identifies several efficient drugs among FDA-approved antineoplastic agents}, year={2020}, language={eng}, issn={2073-4409}, volume={9(2020}, note={Im Titel ist "mut" in IDHmut hochgestellt ; Gesehen am 26.08.2020}, journal={Cells}, doi={10.3390/cells9061389}, } @article{UBHD-68480911, author={Drucker, Elisabeth and Pusch, Stefan and Herpel, Esther and Goeppert, Benjamin and R{\"o}ssler, Stephanie and Schirmacher, Peter and Breuhahn, Kai}, title={Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer}, year={2019}, pages={14 S.}, language={eng}, issn={1478-811X}, volume={17(2019}, note={Gesehen am 27.01.2020}, journal={Cell communication and signaling}, doi={10.1186/s12964-019-0456-x}, } @article{UBHD-68378674, author={Goeppert, Benjamin and Truckenm{\"u}ller, Felicia and Albrecht, Thomas and Fraas, Angelika and Scherer, Dominique and González Silos, Rosa and Mehrabi, Arianeb and Pusch, Stefan and Lorenzo Bermejo, Justo and Schirmacher, Peter and Renner, Marcus and R{\"o}ssler, Stephanie}, title={Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p}, year={2019}, pages={13 S.}, language={eng}, issn={2045-2322}, volume={9(2019) Artikel-Nummer 4796}, number={13 Seiten}, note={Gesehen am 05.04.2019}, journal={Scientific reports}, doi={10.1038/s41598-019-40857-3}, } @article{UBHD-68409480, author={Hou, Yanghao and Sahm, Felix and Reuss, David and Schrimpf, Daniel and Stichel, Damian and Casalini, Belén and K{\"o}lsche, Christian and Sievers, Philipp and Wefers, Annika K. and Reinhardt, Annekathrin and Ebrahimi, Azadeh and Fernández Klett, Francisco and Pusch, Stefan and Meyer, Jochen and Pfister, Stefan and Jones, David T. W. and Korshunov, Andrey and Deimling, Andreas von and Bertero, Luca}, title={Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA}, year={2019}, pages={837-846}, language={eng}, issn={1432-0533}, volume={137}, number={5}, note={Gesehen am 17.07.2019}, journal={Acta neuropathologica}, doi={10.1007/s00401-019-01969-2}, } @article{UBHD-68803387, author={Kilian, Michael and Friedrich, Mirco and Sanghvi, Khwab and Green, Edward and Pusch, Stefan and Kawauchi, Daisuke and L{\"o}wer, Martin and Sonner, Jana K. and Kr{\"a}mer, Christopher and Zaman, Julia and Jung, Stefanie and Breckwoldt, Michael O. and Willimksy, Gerald and Eichm{\"u}ller, Stefan B. and Deimling, Andreas von and Wick, Wolfgang and Sahm, Felix and Platten, Michael and Bunse, Lukas}, title={T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas}, year={2022}, pages={378-389}, language={eng}, issn={1557-3265}, volume={28}, number={2 vom: Jan.}, note={Published first November 15, 2021 ; Gesehen am 20.01.2022}, journal={Clinical cancer research}, doi={10.1158/1078-0432.CCR-21-1881}, } @article{UBHD-68776052, author={Luiken, Sarah and Fraas, Angelika and Bieg, Matthias and Sugiyanto, Raisatun Nisa and Goeppert, Benjamin and Singer, Stephan and Pl{\"o}ger, Carolin and Warsow, Gregor and Marquardt, Jens and Sticht, Carsten and Torre, Carolina de la and Pusch, Stefan and Mehrabi, Arianeb and Gretz, Norbert and Schlesner, Matthias and Eils, Roland and Schirmacher, Peter and Longerich, Thomas and R{\"o}ssler, Stephanie}, title={NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis}, year={2020}, pages={3128-3144}, language={eng}, issn={1476-5594}, volume={39}, number={15}, note={Gesehen am 02.09.2021}, journal={Oncogene}, doi={10.1038/s41388-020-1198-3}, url={https://doi.org/10.1038/s41388-020-1198-3}, library={UB}, } @article{UBHD-69220693, author={Martija, Antoni Andreu and Krauß, Alexandra and B{\"a}chle, Natalie and Doth, Laura and Christians, Arne and Krunic, Damir and Schneider, Martin and Helm, Dominic and Will, Rainer D. and Hartmann, Christian and Herold-Mende, Christel and Deimling, Andreas von and Pusch, Stefan}, title={EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma}, year={2023}, pages={1-22}, language={eng}, issn={2051-5960}, volume={11}, note={Gesehen am 05.06.2024}, journal={Acta Neuropathologica Communications}, doi={10.1186/s40478-023-01673-z}, } @article{UBHD-68961695, author={Martija, Antoni Andreu and Pusch, Stefan}, title={The multifunctional role of EMP3 in the regulation of membrane receptors associated with IDH-wild-type glioblastoma}, year={2021}, pages={1-17}, language={eng}, issn={1422-0067 and 1661-6596}, volume={22}, note={Gesehen am 07.09.2022}, journal={International journal of molecular sciences}, doi={10.3390/ijms22105261}, } @article{UBHD-68283256, author={Ma, Tianfang and Pusch, Stefan and Deimling, Andreas von}, title={Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1}, year={2017}, pages={6379-6387}, language={eng}, issn={1464-3391}, volume={25}, number={24}, note={Available online 13 October 2017 ; Gesehen am 06.07.2018}, journal={Bioorganic & medicinal chemistry}, doi={10.1016/j.bmc.2017.10.009}, } @article{UBHD-68415193, author={Ma, Tianfang and Zou, Fangxia and Pusch, Stefan and Xu, Yungen and Deimling, Andreas von and Zha, Xiaoming}, title={Inhibitors of mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2)}, subtitle={an update and perspective}, year={2018}, pages={8981-9003}, language={eng}, issn={1520-4804}, volume={61}, number={20}, note={Gesehen am 02.08.2019}, journal={Journal of medicinal chemistry}, doi={10.1021/acs.jmedchem.8b00159}, } @article{UBHD-69067544, author={Meyer, Jochen and Pusch, Stefan and Balß, J{\"o}rg and Capper, David and M{\"u}ller, Wolf C. and Christians, Arne and Hartmann, Christian and Deimling, Andreas von}, title={PCR- and restriction endonuclease-based detection of IDH1 mutations}, year={2010}, pages={298-300}, language={eng}, issn={1750-3639}, volume={20}, number={2}, note={Gesehen am 20.04.2023}, journal={Brain pathology}, doi={10.1111/j.1750-3639.2009.00327.x}, } @article{UBHD-68740442, author={Mohrenz, Isabelle Vanessa and Pusch, Stefan and Capper, David and Balß, J{\"o}rg and Weißert, Susanne and Deimling, Andreas von and Frank, Jan}, title={Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death}, year={2013}, pages={1416-1425}, language={eng}, issn={1573-675X}, volume={18}, number={11}, note={Gesehen am 25.05.2021}, journal={Apoptosis}, doi={10.1007/s10495-013-0877-8}, } @book{UBHD-67935482, author={Navis, Anna C. and Pusch, Stefan and Deimling, Andreas von}, title={Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG}, publisher={BioMed Central}, address={London}, year={2013}, pages={1 Online-Ressource}, language={eng}, note={Aus: Acta Neuropathologica Communications, 1 (2013), Nr. 18. pp. 1-12. ISSN 2051-5960}, url={http://www.ub.uni-heidelberg.de/archiv/19451}, library={UB}, } @article{UBHD-67901930, author={Osswald, Matthias and Lemke, Dieter and Liao, Yunxiang and Pusch, Stefan and Heiland, Sabine and Platten, Michael and Huber, Peter E. and Kuner, Thomas and Deimling, Andreas von and Wick, Wolfgang and Winkler, Frank and Sahm, Felix and Venkataramani, Varun and Blaes, Jonas and Horstmann, Heinz and Wiestler, Benedikt and Ratliff, Miriam and Karimian-Jazi, Kianush and Kurz, Felix T.}, title={Brain tumour cells interconnect to a functional and resistant network}, year={2015}, pages={93-8}, language={eng}, issn={1476-4687}, volume={528}, number={7580}, note={Gesehen am 13.11.2015}, journal={Nature}, doi={10.1038/nature16071}, } @article{UBHD-68013368, author={Ott, Martina and Litzenburger, Ulrike and Rauschenbach, Katharina and Bunse, Lukas and Sahm, Katharina and Sahm, Felix and Pusch, Stefan and Opitz, Christiane and Blaes, Jonas and Deimling, Andreas von and Wick, Wolfgang and Platten, Michael}, title={Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway}, year={2015}, pages={13 S.}, language={eng}, issn={1098-1136}, volume={63}, note={Gesehen am 02.08.2016}, journal={Glia}, doi={10.1002/glia.22734}, } @article{UBHD-68981464, author={Phillips, Emma and Balß, J{\"o}rg and Bethke, Frederic and Pusch, Stefan and Christen, Stefan and Hielscher, Thomas and Schn{\"o}lzer, Martina and Fletcher, Michael and Habel, Antje and Teßmer, Claudia and Brenner, Lisa-Marie and G{\"o}ttmann, Mona and Capper, David and Herold-Mende, Christel and Deimling, Andreas von and Fendt, Sarah-Maria and Goidts, Violaine}, title={PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma}, year={2022}, pages={1-12}, language={eng}, issn={2157-9024}, volume={11}, number={1}, note={Gesehen am 03.11.2022}, journal={Oncogenesis}, doi={10.1038/s41389-022-00433-3}, } @article{UBHD-68217738, author={Pl{\"o}ger, Carolin and Waldburger, Nina and Fraas, Angelika and Goeppert, Benjamin and Pusch, Stefan and Breuhahn, Kai and Schirmacher, Peter and R{\"o}ssler, Stephanie}, title={Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma}, year={2016}, pages={828-842}, language={eng}, issn={1527-3350}, volume={64}, number={3}, note={Gesehen am 06.02.2018}, journal={Hepatology}, doi={10.1002/hep.28684}, } @article{UBHD-68683669, author={Pl{\"o}ger, Carolin and Huth, Thorben and Sugiyanto, Raisatun Nisa and Pusch, Stefan and Goeppert, Benjamin and Singer, Stephan and Tabti, Redouane and Haußer-Siller, Ingrid and Schirmacher, Peter and Désaubry, Laurent and R{\"o}ssler, Stephanie}, title={Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria}, year={2020}, pages={1-14}, language={eng}, issn={2041-4889}, volume={11}, note={Gesehen am 26.01.2021}, journal={Cell death & disease}, doi={10.1038/s41419-020-03220-3}, url={https://doi.org/10.1038/s41419-020-03220-3}, library={UB}, } @article{UBHD-68967785, author={Pl{\"o}ger, Carolin and Schreck, Johannes and Huth, Thorben and Fraas, Angelika and Albrecht, Thomas and Charbel, Alphonse and Ji, Junfang and Singer, Stephan and Breuhahn, Kai and Pusch, Stefan and K{\"o}hler, Bruno Christian and Springfeld, Christoph and Schirmacher, Peter and Mehrabi, Arianeb and Goeppert, Benjamin and R{\"o}ssler, Stephanie}, title={STAT1 and STAT3 exhibit a crosstalk and are associated with increased inflammation in hepatocellular carcinoma}, year={2022}, pages={16 S.}, language={eng}, issn={2072-6694}, volume={14}, note={Published: 23 February 2022 ; Gesehen am 27.09.2022}, journal={Cancers}, doi={10.3390/cancers14051154}, } @book{UBHD-68877171, author={Pusch, Stefan}, organization={Universit{\"a}t Heidelberg}, title={Funktionelle Analyse tumorspezifischer Mutationen der Isocitrat-Dehydrogenase und daraus entwachsene diagnostische und therapeutische Ans{\"a}tze}, address={Heidelberg}, year={2021}, pages={102 Seiten}, language={ger and eng}, note={Publikationsbasierte Habilitationsschrift bestehend aus einem Text und 7 Zeitschriftenaufs{\"a}tzen}, school={Habilitationsschrift, Ruprecht-Karls-Universit{\"a}t Heidelberg, 2021, Kumulative Habilitationsschrift}, library={UB [Signatur: 2022 U 226]}, } @book{UBHD-68879339, author={Pusch, Stefan}, title={Interaktionsanalyse von CDKA}, subtitle={1 und anderen Zellzyklusregulatoren aus Arabidopsis thaliana}, address={157 S.}, year={2008}, pages={Ill., graph. Darst.}, language={ger}, note={Auch elektronisch verf{\"u}gbar {\"u}ber die Homepage der USB K{\"o}ln}, school={K{\"o}ln, Univ., Diss., 2008}, } @book{UBHD-68879285, author={Pusch, Stefan}, title={Interaktionsanalyse von CDKA;1 und anderen Zellzyklusregulatoren aus Arabidopsis thaliana}, year={2008}, pages={Online-Ressource (PDF-Datei: 158 S., 2972 KB)}, language={ger}, school={K{\"o}ln, Univ., Diss., 2008}, keywords={Ackerschmalwand / Zellzyklus / Genregulation}, } @article{UBHD-68124397, author={Pusch, Stefan and Fischer, Viktoria and Ott, Martina and Schrimpf, Daniel and Capper, David and Sahm, Felix and Wick, Wolfgang and Unterberg, Andreas and Herold-Mende, Christel and Platten, Michael and Deimling, Andreas von}, title={Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo}, year={2017}, pages={629-644}, language={eng}, issn={1432-0533}, volume={133}, number={4}, note={Gesehen am 31.05.2017}, journal={Acta neuropathologica}, doi={10.1007/s00401-017-1677-y}, } @article{UBHD-68862212, author={Reuss, David and Piro, Rosario M. and Jones, David T. W. and Simon, Matthias and Ketter, Ralf and Kool, Marcel and Becker, Albert and Sahm, Felix and Pusch, Stefan and Meyer, Jochen and Hagenlocher, Christian and Schweizer, Leonille and Capper, David and Vollmuth, Philipp and Mucha, Jana and K{\"o}lsche, Christian and J{\"a}ger, Natalie and Santarius, Thomas and Tarpey, Patrick S. and Stephens, Philip J. and Futreal, P. Andrew and Wellenreuther, Ruth and Kraus, J{\"u}rgen and Lenartz, Doris and Herold-Mende, Christel and Hartmann, Christian and Mawrin, Christian and Giese, Nathalia and Eils, Roland and Collins, V. Peter and K{\"o}nig, Rainer and Wiestler, Otmar D. and Pfister, Stefan and Deimling, Andreas von}, title={Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations}, year={2013}, pages={351-358}, language={eng}, issn={1432-0533}, volume={125}, number={3}, note={Gesehen am 04.01.2022}, journal={Acta neuropathologica}, doi={10.1007/s00401-013-1093-x}, } @article{UBHD-68260821, author={Sahm, Felix and Capper, David and Pusch, Stefan and Balß, J{\"o}rg and Koch, Arend Wolfgang and Langhans, Claus-Dieter and Okun, J{\"u}rgen G. and Deimling, Andreas von}, title={Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry}, year={2012}, pages={26-31}, language={eng}, issn={1750-3639}, volume={22}, number={1}, note={Gesehen am 13.06.2018 ; First published 02 June 2011}, journal={Brain pathology}, doi={10.1111/j.1750-3639.2011.00506.x}, } @article{UBHD-68260827, author={Sahm, Felix and K{\"o}lsche, Christian and Meyer, Jochen and Pusch, Stefan and M{\"u}ller, Wolf C. and Herold-Mende, Christel and Deimling, Andreas von and Hartmann, Christian}, title={CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas}, year={2012}, pages={7 S.}, language={eng}, issn={1432-0533}, volume={123}, note={Gesehen am 13.06.2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-012-0993-5}, } @article{UBHD-68614953, author={Schweizer, Leonille and K{\"o}lsche, Christian and Sahm, Felix and Piro, Rosario M. and Capper, David and Reuss, David and Pusch, Stefan and Habel, Antje and Meyer, Jochen and G{\"o}ck, Tanja and Jones, David T. W. and Mawrin, Christian and Schittenhelm, Jens Florian and Becker, Albert and Heim, Stephanie and Simon, Matthias and Herold-Mende, Christel and Mechtersheimer, Gunhild and Paulus, Werner and K{\"o}nig, Rainer and Wiestler, Otmar D. and Pfister, Stefan and Deimling, Andreas von}, title={Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein}, year={2013}, pages={651-658}, language={eng}, issn={1432-0533}, volume={125}, number={5}, journal={Acta neuropathologica}, doi={10.1007/s00401-013-1117-6}, } @article{UBHD-68647390, author={Usta, Diren and Sigaud, Romain and Buhl, Juliane and Selt, Florian and Marquardt, Viktoria and Pauck, David and Jansen, Jennifer and Pusch, Stefan and Ecker, Jonas and Hielscher, Thomas and Vollmer, Johanna and Sommerkamp, Alexander C. and Rubner, Tobias and Hargrave, Darren and Tilburg, Cornelis M. van and Pfister, Stefan and Jones, David T. W. and Remke, Marc and Brummer, Tilman and Witt, Olaf and Milde, Till}, title={A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells}, year={2020}, pages={1737-1750}, language={eng}, issn={1538-8514}, volume={19}, number={8}, note={Gesehen am 12.10.2020}, journal={Molecular cancer therapeutics}, doi={10.1158/1535-7163.MCT-19-1021}, } @article{UBHD-68563985, author={Ventura Ferreira, Mónica Sofia and Sørensen, Mia Dahl and Pusch, Stefan and Beier, Dagmar and Bouillon, Anne-Sophie and Kristensen, Bjarne Winther and Br{\"u}mmendorf, Tim Henrik and Beier, Christoph Patrick and Beier, Fabian}, title={Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation}, year={2020}, pages={1-14}, language={eng}, issn={1573-7373}, volume={147}, number={1}, note={Gesehen am 14.04.2020}, journal={Journal of neuro-oncology}, doi={10.1007/s11060-020-03394-y}, } @article{UBHD-68480394, author={Wirthschaft, Peter and Kr{\"u}wel-Bode, Julia and Soni, Himanshu and Dietrich, Fabio and Kr{\"u}wel, Thomas and Fischer, Bernd and Knobbe-Thomsen, Christiane B. and Rossetti, Giulia and Hentschel, Andreas and Mack, Norman and Sch{\"o}nig, Kai and Breckwoldt, Michael O. and Schmandke, André and Pusch, Stefan and Medenbach, Jan and Bendszus, Martin and Schwab, Martin E. and Deimling, Andreas von and Kool, Marcel and Herold-Mende, Christel and Reifenberger, Guido and Ahrends, Robert and Tews, Bj{\"o}rn}, title={RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas}, year={2019}, pages={275-293}, language={eng}, issn={1432-0533}, volume={138}, number={2}, note={Gesehen am 24.01.2020 ; Received: 25 November 2018}, journal={Acta neuropathologica}, doi={10.1007/s00401-019-02021-z}, } @article{UBHD-68620517, author={Yang, Lijun and Pusch, Stefan and Jennings, Victoria and Ma, Tianfang and Zhu, Qihua and Xu, Yungen and Deimling, Andreas von and Zha, Xiaoming}, title={Identification of new inhibitors of mutant isocitrate dehydrogenase 2 through molecular similarity-based virtual screening}, year={2019}, pages={861-867}, language={eng}, issn={1875-628X}, volume={16}, number={8}, note={Gesehen am 23.07.2020}, journal={Letters in drug design & discovery}, doi={10.2174/1570180815666180808094432}, } @article{UBHD-68482921, author={Zhang, Ying and Pusch, Stefan and Innes, James and Sidlauskas, Kastytis and Ellis, Matthew and Lau, Joanne and El-Hassan, Tedani and Aley, Natasha and Launchbury, Francesca and Richard-Loendt, Angela and deBoer, Jasper and Chen, Sheng and Wang, Lei and Deimling, Andreas von and Li, Ningning and Brandner, Sebastian}, title={Mutant IDH sensitizes gliomas to endoplasmic reticulum stress and triggers apoptosis via miR-183-mediated inhibition of semaphorin 3E}, year={2019}, pages={4994-5007}, language={eng}, issn={1538-7445}, volume={79}, number={19}, note={Gesehen am 31.01.2020}, journal={Cancer research}, doi={10.1158/0008-5472.CAN-19-0054}, } @article{UBHD-68561067, author={Zou, Fangxia and Pusch, Stefan and Deimling, Andreas von}, title={Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening}, year={2018}, pages={388-393}, language={eng}, issn={1464-3405}, volume={28}, number={3}, note={Available online 13 December 2017 ; Gesehen am 24.06.2020}, journal={Bioorganic & medicinal chemistry letters}, doi={10.1016/j.bmcl.2017.12.030}, } @article{UBHD-68298922, author={Zou, Fangxia and Pusch, Stefan and Deimling, Andreas von}, title={Identification of a novel selective inhibitor of mutant isocitrate dehydrogenase 1 at allosteric site by docking-based virtual screening}, year={2016}, pages={96735-96742}, language={eng}, issn={2046-2069}, volume={6}, number={99}, note={Gesehen am 10.12.2019}, journal={RSC Advances}, doi={10.1039/C6RA21617J}, }