@article{UBHD-68497965,
  author={Freire Valls, Aida and Knipper, Karl and Giannakouri, Evangelia and Sarachaga, Víctor and Hinterkopf, Sascha and W{\"u}hrl, Michael and Shen, Ying and Radhakrishnan, Praveen and Klose, Johannes and Ulrich, Alexis and Schneider, Martin and Augustin, Hellmut and Ruiz de Almodóvar, Carmen and Schmidt, Thomas},
  title={VEGFR1+ metastasis-associated macrophages contribute to metastatic angiogenesis and influence colorectal cancer patient outcome},
  year={2019},
  pages={5674-5685},
  language={eng},
  issn={1557-3265},
  volume={25},
  number={18},
  note={Gesehen am 05.03.2020 ; Das Zeichen "+" ist im Titel hochgestellt},
  journal={Clinical cancer research},
  doi={10.1158/1078-0432.CCR-18-2123},
}
@article{UBHD-68865726,
  author={Friedrichs, Juliane and Seide, Svenja and Vey, Johannes and Zimmermann, Samuel and Hardt, Julia and Kleeff, J{\"o}rg H. and Klose, Johannes and Michalski, Christoph and Kieser, Meinhard and Pilz, Maximilian and Ronellenfitsch, Ulrich},
  title={Interventions to reduce the incidence of surgical site infection in colorectal resections: systematic review with multicomponent network meta-analysis (INTRISSI)},
  subtitle={study protocol},
  year={2021},
  pages={1-7},
  language={eng},
  issn={2044-6055},
  volume={11},
  note={Gesehen am 12.01.2022},
  journal={BMJ open},
  doi={10.1136/bmjopen-2021-057226},
}
@article{UBHD-69079319,
  author={Gomes dos Santos Ferreira Rebelo, Artur Luis and Klose, Johannes and Kleeff, J{\"o}rg H. and Ronellenfitsch, Ulrich},
  title={Is it feasible and ethical to randomize patients between surgery and non-surgical treatments for gastrointestinal cancers?},
  year={2023},
  pages={1-6},
  language={eng},
  issn={2234-943X},
  volume={13(2023) vom: M{\"a}rz},
  number={Artikel-ID 1119436},
  journal={Frontiers in oncology},
  doi={10.3389/fonc.2023.1119436},
}
@article{UBHD-68911478,
  author={Gomes dos Santos Ferreira Rebelo, Artur Luis and Ukkat, J{\"o}rg and Klose, Johannes and Ronellenfitsch, Ulrich and Kleeff, J{\"o}rg H.},
  title={Surgery with arterial resection for hilar cholangiocarcinoma},
  subtitle={protocol for a systematic review and meta-analysis},
  year={2021},
  pages={1-5},
  language={eng},
  issn={1929-0748},
  volume={10},
  journal={JMIR Research Protocols},
  doi={10.2196/31212},
}
@article{UBHD-68992637,
  author={Gomes dos Santos Ferreira Rebelo, Artur Luis and Friedrichs, Juliane and Grilli, Maurizio and Wahbeh, Nour and Partsakhashvili, Jumber and Ukkat, J{\"o}rg and Klose, Johannes and Ronellenfitsch, Ulrich and Kleeff, J{\"o}rg H.},
  title={Systematic review and meta-analysis of surgery for hilar cholangiocarcinoma with arterial resection},
  year={2022},
  pages={1600-1614},
  language={eng},
  issn={1477-2574},
  volume={24},
  number={10},
  note={Available online 14 April 2022},
  journal={HPB},
  doi={10.1016/j.hpb.2022.04.002},
}
@article{UBHD-69079316,
  author={Kleeff, J{\"o}rg H. and Klose, Johannes and Gomes dos Santos Ferreira Rebelo, Artur Luis and Ronellenfitsch, Ulrich},
  title={Editorial},
  subtitle={perioperative optimization of patients undergoing pancreatic surgery},
  year={2023},
  pages={1-2},
  language={eng},
  issn={2234-943X},
  volume={13(2023) vom: M{\"a}rz},
  number={Artikel-ID 1170409},
  journal={Frontiers in oncology},
  doi={10.3389/fonc.2023.1170409},
}
@article{UBHD-68959003,
  author={Klose, Johannes and Kloor, Matthias and Warschkow, René and Antony, Pia-Anita and Liesenfeld, Lukas and B{\"u}chler, Markus W. and Schneider, Martin and Tarantino, Ignazio},
  title={Does side really matter?},
  subtitle={Survival analysis among patients with right- versus left-sided colon cancer : a propensity score-adjusted analysis},
  year={2021},
  pages={2768-2778},
  language={eng},
  issn={1534-4681},
  volume={28},
  number={5},
  note={Published online: 21 September 2020},
  journal={Annals of surgical oncology},
  doi={10.1245/s10434-020-09116-y},
}
@article{UBHD-68579602,
  author={Klose, Johannes and Hackert, Thilo and B{\"u}chler, Markus W. and Ulrich, Alexis},
  title={Gef{\"a}ßresektionen und -rekonstruktionen in der Pankreaschirurgie},
  year={2016},
  pages={94-99},
  language={ger},
  issn={1433-0385},
  volume={87},
  number={2},
  note={Gesehen am 20.05.2020},
  journal={Der Chirurg},
  editor={Ewerbeck, Volker},
  doi={10.1007/s00104-015-0134-5},
}
@article{UBHD-68614770,
  author={Klose, Johannes and Tarantino, Ignazio and Schmidt, Thomas and Bruckner, Thomas and Kulu, Yakup and Wagner, Jan Tobias and Schneider, Martin and B{\"u}chler, Markus W. and Ulrich, Alexis},
  title={Impact of anatomic location on locally recurrent rectal cancer},
  subtitle={superior outcome for intraluminal tumour recurrence},
  year={2015},
  pages={1123-1131},
  language={eng},
  issn={1873-4626},
  volume={19},
  number={6},
  note={Gesehen am 08.07.2020},
  journal={Journal of gastrointestinal surgery},
  doi={10.1007/s11605-015-2804-5},
}
@article{UBHD-67742983,
  author={Klose, Johannes and Panayotova Dimitrova, Diana},
  title={Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells},
  year={2014},
  pages={11 S.},
  language={eng},
  issn={1932-6203},
  volume={9(2014},
  note={Gesehen am 04.12.2014},
  journal={PLOS ONE},
  doi={10.1371/journal.pone.0095970},
  url={http://www.ncbi.nlm.nih.gov/pubmed/24816744},
  library={UB},
}
@article{UBHD-68992604,
  author={Klose, Johannes and Ronellenfitsch, Ulrich and Kleeff, J{\"o}rg H.},
  title={Management problems in patients with pancreatic cancer from a surgeon's perspective},
  year={2021},
  pages={76-83},
  language={eng},
  issn={1532-8708},
  volume={48},
  number={1},
  journal={Seminars in oncology},
  doi={10.1053/j.seminoncol.2021.02.008},
}
@article{UBHD-68453616,
  author={Klose, Johannes and Tarantino, Ignazio and Kulu, Yakup and Bruckner, Thomas and Volz, Claudia and Schmidt, Thomas and Schneider, Martin and B{\"u}chler, Markus W. and Ulrich, Alexis},
  title={A nomogram to predict anastomotic leakage in open rectal surgery},
  subtitle={hope or hype?},
  year={2018},
  pages={1619-1630},
  language={eng},
  issn={1873-4626},
  volume={22},
  number={9},
  note={Gesehen am 12.11.2019},
  journal={Journal of gastrointestinal surgery},
  doi={10.1007/s11605-018-3782-1},
}
@article{UBHD-68653357,
  author={Klose, Johannes},
  title={Outcome stagnation of liver transplantation for primary sclerosing cholangitis in the Model for End-stage Liver Disease era},
  year={2014},
  pages={1021-1029},
  language={eng},
  issn={1435-2451},
  volume={399},
  number={8},
  note={Gesehen am 23.10.2020},
  journal={Langenbeck's archives of surgery},
  doi={10.1007/s00423-014-1214-6},
}
@article{UBHD-68565788,
  author={Klose, Johannes and Lasitschka, Felix and Horsch, Cornelia and Strowitzki, Moritz and Bruckner, Thomas and Volz, Claudia and Schmidt, Thomas and Schneider, Martin},
  title={Prognostic relevance of programmed death-ligand 1 expression and microsatellite status in small bowel adenocarcinoma},
  year={2020},
  pages={321-329},
  language={eng},
  issn={1502-7708},
  volume={55},
  number={3},
  note={Gesehen am 17.04.2020},
  journal={Scandinavian journal of gastroenterology},
  doi={10.1080/00365521.2020.1734073},
}
@article{UBHD-68413237,
  author={Klose, Johannes and Radhakrishnan, Praveen and Volz, Claudia and Schmidt, Thomas and Ulrich, Alexis and Dieter, Sebastian M. and Ball, Claudia R. and Glimm, Hanno and Schneider, Martin},
  title={Salinomycin},
  subtitle={anti-tumor activity in a pre-clinical colorectal cancer model},
  year={2019},
  pages={20 S.},
  language={eng},
  issn={1932-6203},
  volume={14(2019},
  note={Gesehen am 29.07.2019},
  journal={PLOS ONE},
  doi={10.1371/journal.pone.0211916},
  url={https://doi.org/10.1371/journal.pone.0211916},
  library={UB},
}
@book{UBHD-68058879,
  author={Klose, Johannes and Eissele, Jana and Volz, Claudia and Ritter, Alina and Shen, Ying and Schmidt, Thomas and Heger, Ulrike and Schneider, Martin and Ulrich, Alexis},
  title={Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133+ human colorectal cancer cells},
  publisher={BioMed Central; Springer},
  address={London; Berlin; Heidelberg},
  year={2016},
  pages={1 Online-Ressource (15 Seiten)},
  language={eng},
  note={Aus: BMC Cancer, 16 (2016), Nr. 896. pp. 1-15. ISSN 1471-2407 ; Im Titel ist das Pluszeichen hochgestellt},
  doi={10.1186/s12885-016-2879-8},
  url={https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-221869},
  library={UB},
}
@article{UBHD-68067176,
  author={Klose, Johannes and Eissele, Jana and Volz, Claudia and Ritter, Alina and Shen, Ying and Schmidt, Thomas and Heger, Ulrike and Schneider, Martin and Ulrich, Alexis},
  title={Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133+ human colorectal cancer cells},
  year={2016},
  language={eng},
  issn={1471-2407},
  volume={16(2016) Artikel-Nummer 896},
  number={15 Seiten},
  note={Gesehen am 21.12.2016 ; Im Titel ist das Pluszeichen hochgestellt},
  journal={BMC cancer},
  doi={10.1186/s12885-016-2879-8},
  url={http://dx.doi.org/10.1186/s12885-016-2879-8},
  library={UB},
}
@article{UBHD-68320118,
  author={Klose, Johannes and Schmidt, Thomas and Schneider, Martin and Ulrich, Alexis},
  title={Salinomycin inhibits cholangiocarcinoma growth by inhibition of autophagic flux},
  year={2018},
  pages={3619-3630},
  language={eng},
  issn={1949-2553},
  volume={9},
  number={3},
  note={Published: December 16, 2017 ; Gesehen am 23.10.2018},
  journal={OncoTarget},
  doi={10.18632/oncotarget.23339},
}
@article{UBHD-68320119,
  author={Klose, Johannes and Volz, Claudia and Schmidt, Thomas and Schneider, Martin and Ulrich, Alexis},
  title={Semi-synthetic salinomycin analogs exert cytotoxic activity against human colorectal cancer stem cells},
  year={2018},
  pages={53-59},
  language={eng},
  issn={1090-2104},
  volume={495},
  number={1},
  note={Available online 28 October 2017 ; Gesehen am 23.10.2018},
  journal={Biochemical and biophysical research communications},
  doi={10.1016/j.bbrc.2017.10.147},
}
@article{UBHD-68305017,
  author={Klose, Johannes and Tarantino, Ignazio and Kulu, Yakup and Bruckner, Thomas and Schmidt, Thomas and Schneider, Martin and Hackert, Thilo and B{\"u}chler, Markus W. and Ulrich, Alexis},
  title={Sphincter-preserving surgery for low rectal cancer},
  subtitle={do we overshoot the mark?},
  year={2017},
  pages={885-891},
  language={eng},
  issn={1873-4626},
  volume={21},
  number={5},
  note={Gesehen am 14.09.2018},
  journal={Journal of gastrointestinal surgery},
  doi={10.1007/s11605-016-3339-0},
}
@article{UBHD-68845913,
  author={Klose, Johannes and Schmitt, Annelene and Pernthaler, Julia and Warschkow, René and B{\"u}chler, Markus W. and Schneider, Martin and Lasitschka, Felix and Tarantino, Ignazio},
  title={Still proliferating CD44+/Ki67+ tumor cells after neoadjuvant radiochemotherapy identify rectal cancer patients with poor survival},
  year={2021},
  pages={2078-2086},
  language={eng},
  issn={1532-2157},
  volume={47},
  number={8},
  note={Gesehen am 20.12.2021 ; Im Titel sind die Zeichen "+" hochgestellt},
  journal={European journal of surgical oncology},
  doi={10.1016/j.ejso.2021.03.250},
}
@article{UBHD-69216510,
  author={Klose, Johannes and Rieder, Simon and Ronellenfitsch, Ulrich},
  title={Surgical and interventional treatment options in unresectable gastrointestinal cancer},
  year={2021},
  pages={1-7},
  language={eng},
  issn={2666-2620},
  volume={5},
  number={Artikel-ID 100037},
  journal={Surgery in practice and science},
  doi={10.1016/j.sipas.2021.100037},
}
@book{UBHD-68485495,
  author={Klose, Johannes},
  organization={Universit{\"a}t Heidelberg},
  title={Untersuchungen zur Wirksamkeit und zum Wirkmechanismus von Salinomycin in gastrointestinalen Tumorerkrankungen},
  address={Heidelberg},
  year={2019},
  pages={160 Bl{\"a}tter},
  language={ger},
  note={Publikationsbasierte Habilitationsschrift bestehend aus einem Text und 6 Zeitschriftenaufs{\"a}tzen},
  school={Habilitationsschrift,  Ruprecht-Karls-Universit{\"a}t Heidelberg,  2019,  Kumulative Habilitationsschrift},
  library={UB [Signatur: 2020 U 149]},
}
@article{UBHD-69216486,
  author={Klose, Michelle A. and Walldorf, Jens and Damm, Marko and Krug, Sebastian and Klose, Johannes and Ronellenfitsch, Ulrich and Kleeff, J{\"o}rg H. and Michl, Patrick and Rosendahl, Jonas},
  title={Treatment of esophageal leakages with the Microtech®-VAC-Stent},
  subtitle={a monocentric early experience of three cases},
  year={2023},
  pages={1-7},
  language={eng},
  issn={2631-7745},
  volume={16(2023) vom: Jan./Dez.},
  journal={Therapeutic advances in gastrointestinal endoscopy},
  doi={10.1177/26317745231200312},
}
@article{UBHD-68389552,
  author={Kulu, Yakup and Mehrabi, Arianeb and Khajeh, Elias and Klose, Johannes and Greenwood, Johanna and Hackert, Thilo and B{\"u}chler, Markus W. and Ulrich, Alexis},
  title={Promising long-term outcomes ffter pelvic exenteration},
  year={2019},
  pages={1340-1349},
  language={eng},
  issn={1534-4681},
  volume={26},
  number={5},
  note={Gesehen am 14.05.2019 ; Published Online: 5 December 2018},
  journal={Annals of surgical oncology},
  doi={10.1245/s10434-018-07090-0},
}
@article{UBHD-69098532,
  author={Liesenfeld, Lukas and Wagner, Benedikt and Hillebrecht, Christian and Brune, Maik and Eckert, Christoph and Klose, Johannes and Schmidt, Thomas and B{\"u}chler, Markus W. and Schneider, Martin},
  title={HIPEC-induced acute kidney injury},
  subtitle={a retrospective clinical study and preclinical model},
  year={2022},
  pages={139-151},
  language={eng},
  issn={1534-4681},
  volume={29},
  number={1},
  note={Gesehen am 17.07.2023},
  journal={Annals of surgical oncology},
  doi={10.1245/s10434-021-10376-5},
  url={https://doi.org/10.1245/s10434-021-10376-5},
  library={UB},
}
@article{UBHD-68630883,
  author={Liesenfeld, Lukas and Hillebrecht, Christian and Klose, Johannes and Schmidt, Thomas and Schneider, Martin},
  title={Impact of perfusate concentration on hyperthermic intraperitoneal chemotherapy efficacy and toxicity in a rodent model},
  year={2020},
  pages={262-271},
  language={eng},
  issn={1095-8673},
  volume={253},
  note={Gesehen am 25.08.2020},
  journal={Journal of surgical research},
  doi={10.1016/j.jss.2020.03.067},
}
@article{UBHD-68495324,
  author={Nienh{\"u}ser, Henrik and Heger, Patrick and Kulu, Yakup and Diener, Markus K. and Klose, Johannes and Schneider, Martin and M{\"u}ller, Beat P. and Ulrich, Alexis and B{\"u}chler, Markus W. and Mihaljevic, André Leopold and Schmidt, Thomas},
  title={Short- and long-term oncological outcome after rectal cancer surgery},
  subtitle={a systematic review and meta-analysis comparing open versus laparoscopic rectal cancer surgery},
  year={2018},
  pages={1418-1433},
  language={eng},
  issn={1873-4626},
  volume={22},
  number={8},
  note={Gesehen am 02.03.2020},
  journal={Journal of gastrointestinal surgery},
  doi={10.1007/s11605-018-3738-5},
}
@article{UBHD-68380296,
  author={Ramackers, Wolf-R{\"u}diger and Klose, Johannes},
  title={Investigation of the influence of xenoreactive antibodies on activation of complement and coagulation in an ex vivo perfusion animal study using porcine kidneys},
  year={2019},
  pages={546-556},
  language={eng},
  issn={1432-2277},
  volume={32},
  number={5},
  note={First published: 30 December 2018 ; Version of record online: 22 January 2019 ; Gesehen am 12.04.2019},
  journal={Transplant international},
  doi={10.1111/tri.13396},
}
@article{UBHD-68992603,
  author={Ronellenfitsch, Ulrich and Klose, Johannes and Kleeff, J{\"o}rg H.},
  title={Multimodal therapy of upper gastrointestinal malignancies},
  subtitle={editorial},
  year={2021},
  pages={1-5},
  language={eng},
  issn={2072-6694},
  volume={13},
  journal={Cancers},
  doi={10.3390/cancers13040793},
}
@article{UBHD-68560254,
  author={Schmidt, Thomas and Nienh{\"u}ser, Henrik and Kuna, Constantin and Klose, Johannes and Strowitzki, Moritz and B{\"u}chler, Markus W. and Ulrich, Alexis and Schneider, Martin},
  title={Prognostic indicators lose their value with repeated resection of colorectal liver metastases},
  year={2018},
  pages={1610-1618},
  language={eng},
  issn={1532-2157},
  volume={44},
  number={10},
  note={Available online 31 July 2018 ; Gesehen am 01.04.2020},
  journal={European journal of surgical oncology},
  doi={10.1016/j.ejso.2018.07.051},
}
@article{UBHD-68049270,
  author={Schmidt, Thomas and Alldinger, Ingo and Blank, Susanne and Klose, Johannes and Springfeld, Christoph and Dreikhausen, Lena and Weichert, Wilko and Grenacher, Lars and Bruckner, Thomas and Ulrich, Alexis and B{\"u}chler, Markus W. and Ott, Katja},
  title={Surgery in oesophago-gastric cancer with metastatic disease},
  subtitle={treatment, prognosis and preoperative patient selection},
  year={2015},
  pages={1340-1347},
  language={eng},
  issn={1532-2157},
  volume={41},
  number={10},
  note={Gesehen am 10.11.2016},
  journal={European journal of surgical oncology},
  doi={10.1016/j.ejso.2015.05.005},
}
@article{UBHD-69216462,
  author={Simoes, Joana F. F. and Nepogodiev, Dmitri and Ademuyiwa, Adesoji and Buarque, Igor and El-Boghdadly, Kariem and Gebreyohanes, Mengistu and Glasbey, James C. and Kronberger, Irmgard E. and Kruijff, Schelto and Li, Elizabeth and L{\"o}ffler, Markus W. and Mashbari, Hassan and Pata, Francesco and Smart, Neil and Sayyed, Raza and Shu, Sebastian and Sund, Malin and Bhangu, Aneel and Kisser, Ulrich and Kleeff, J{\"o}rg H. and Klose, Johannes and Lorenz, Kerstin and Papendick, Nancy and Plontke, Stefan K.-R. and Ronellenfitsch, Ulrich and Seiwerth, Ingmar and Thomssen, Christoph and Ukkat, J{\"o}rg},
  title={Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery},
  subtitle={an international prospective cohort study},
  year={2021},
  pages={1454-1464},
  language={eng},
  issn={1365-2044},
  volume={76},
  number={11 vom: Nov.},
  note={Online ver{\"o}ffentlicht: . August 2021},
  journal={Anaesthesia},
  doi={10.1111/anae.15560},
}
@article{UBHD-68434610,
  author={St{\"o}th, Manuel and Freire Valls, Aida and Chen, Mingyi and Hidding, Sarah and Knipper, Karl and Shen, Ying and Klose, Johannes and Ulrich, Alexis and Ruiz de Almodóvar, Carmen and Schneider, Martin and Schmidt, Thomas},
  title={Splenectomy reduces lung metastases and tumoral and metastatic niche inflammation},
  year={2019},
  pages={2509-2520},
  language={eng},
  issn={0020-7136},
  volume={145},
  number={9},
  note={Gesehen am 01.10.2019},
  journal={International journal of cancer},
  doi={10.1002/ijc.32378},
}
@article{UBHD-68480872,
  author={Strowitzki, Moritz and Radhakrishnan, Praveen and Ritter, Alina and Volz, Claudia and Harnoß, Jonathan M. and Klose, Johannes and Schmidt, Thomas and Schneider, Martin},
  title={High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases},
  year={2019},
  pages={675-688},
  language={eng},
  issn={1532-1827},
  volume={120},
  number={7},
  note={Gesehen am 27.01.2020},
  journal={British journal of cancer},
  doi={10.1038/s41416-019-0406-9},
}
@article{UBHD-68568243,
  author={Strowitzki, Moritz and Schmidt, Thomas and Keppler, Ulrich and Ritter, Alina and Klose, Johannes and Mihaljevic, André Leopold and Schneider, Martin and B{\"u}chler, Markus W. and Ulrich, Alexis},
  title={Influence of neoadjuvant chemotherapy on resection of primary colorectal liver metastases},
  subtitle={A propensity score analysis},
  year={2017},
  pages={149-158},
  language={eng},
  issn={1096-9098},
  volume={116},
  number={2},
  note={Gesehen am 20.04.2020},
  journal={Journal of surgical oncology},
  doi={10.1002/jso.24631},
}
@article{UBHD-68752598,
  author={Strowitzki, Moritz and Kimmer, Gwendolyn and Wehrmann, Julian and Ritter, Alina and Radhakrishnan, Praveen and Opitz, Vanessa M. and Tuffs, Christopher and Biller, Marvin and Kugler, Julia and Keppler, Ulrich and Harnoß, Jonathan M. and Klose, Johannes and Schmidt, Thomas and Blanco, Alfonso and Taylor, Cormac T. and Schneider, Martin},
  title={Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses},
  year={2021},
  pages={1-17},
  language={eng},
  issn={2379-3708},
  volume={6},
  number={8},
  note={Gesehen am 25.06.2021},
  journal={JCI insight},
  doi={10.1172/jci.insight.139191},
}
@article{UBHD-69216527,
  author={Wadewitz, Elisabeth and Friedrichs, Juliane and Grilli, Maurizio and Vey, Johannes and Zimmermann, Samuel and Kleeff, J{\"o}rg H. and Ronellenfitsch, Ulrich and Klose, Johannes and Gomes dos Santos Ferreira Rebelo, Artur Luis},
  title={Approaches for the treatment of perforated peptic ulcers},
  subtitle={a network meta-analysis of randomised controlled trials - study protocol},
  year={2024},
  pages={1-6},
  language={eng},
  issn={2044-6055},
  volume={14},
  journal={BMJ open},
  doi={10.1136/bmjopen-2023-082732},
}