@article{UBHD-68896366, author={Arlt, Volker M. and Singh, Rajinder and Stiborová, Marie and Costa, Gonçalo Gamboa da and Frei, Eva and Evans, James D. and Farmer, Peter B. and Wolf, C. Roland and Henderson, Colin J. and Phillips, David H.}, title={Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null mice}, year={2011}, pages={2169-2173}, language={eng}, issn={1521-009X}, volume={39}, number={12}, note={Gesehen am 18.03.2022}, journal={Drug metabolism and disposition}, doi={10.1124/dmd.111.041343}, } @article{UBHD-68624244, author={Arlt, Volker M. and Frei, Eva}, title={Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene}, year={2015}, pages={213-225}, language={eng}, issn={1096-0929}, volume={146}, number={2}, note={Gesehen am 05.08.2020}, journal={Toxicological sciences}, doi={10.1093/toxsci/kfv086}, } @article{UBHD-68896365, author={Arlt, Volker M. and Levová, Kateřina and Bárta, František and Shi, Zhanquan and Evans, James D. and Frei, Eva and Schmeiser, Heinz H. and Nebert, Daniel W. and Phillips, David H. and Stiborová, Marie}, title={Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I}, subtitle={studies in Cyp1a1(−/−), Cyp1a2(−/−), and Cyp1a1/1a2(−/−) mice}, year={2011}, pages={1710-1719}, language={eng}, issn={1520-5010}, volume={24}, number={10}, note={Gesehen am 18.03.2022}, journal={Chemical research in toxicology}, doi={10.1021/tx200259y}, } @article{UBHD-68084103, author={Beyerle, Jolantha and Frei, Eva and Habermann, Nina and Ulrich, Cornelia}, title={Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer}, year={2015}, pages={199-221}, language={eng}, issn={1097-9883}, volume={47}, number={2}, note={Gesehen am 14.02.2017}, journal={Drug metabolism reviews}, doi={10.3109/03602532.2014.996649}, } @article{UBHD-68569387, author={Beyerle, Jolantha and Holowatyj, Andreana N. and Haffa, Mariam and Frei, Eva and Gigić, Biljana and Schrotz-King, Petra and Boehm, Juergen and Habermann, Nina and Stiborova, Marie and Scherer, Dominique and K{\"o}lsch, Torsten and Skender, Stephanie and Becker, Nikolaus and Herpel, Esther and Schneider, Martin and Ulrich, Alexis and Schirmacher, Peter and Chang-Claude, Jenny and Brenner, Hermann and Hoffmeister, Michael and Haug, Ulrike and Owen, Robert and Ulrich, Cornelia}, title={Expression patterns of xenobiotic-metabolizing enzymes in tumor and adjacent normal mucosa tissues among patients with colorectal cancer}, subtitle={the ColoCare Study}, year={2020}, pages={460-469}, language={eng}, issn={1538-7755}, volume={29}, number={2}, note={Published online first November 18, 2019 ; Gesehen am 22.04.2020}, journal={Cancer epidemiology, biomarkers & prevention}, doi={10.1158/1055-9965.EPI-19-0449}, } @article{UBHD-68930173, author={Ding, Reinhard and Frei, Eva and Fardanesh, Mahmoudreza and Schrenk, Hans-Hermann and Kremer, Paul and Haefeli, Walter E.}, title={Pharmacokinetics of 5-Aminofluorescein-Albumin, a novel fluorescence marker of brain tumors during surgery}, year={2011}, pages={7 S.}, language={eng}, issn={1552-4604}, volume={51}, note={Elektronische Reproduktion der Druck-Ausgabe ; Gesehen am 13.06.2022}, journal={Journal of clinical pharmacology}, doi={10.1177/0091270010372626}, } @article{UBHD-69048728, author={Frei, Eva}, title={Albumin binding ligands and albumin conjugate uptake by cancer cells}, year={2011}, pages={1-4}, language={eng}, issn={1758-5996}, volume={3}, number={Artikel-ID 11}, note={Gesehen am 07.03.2023}, journal={Diabetology & metabolic syndrome}, doi={10.1186/1758-5996-3-11}, } @article{UBHD-68354681, author={Frei, Eva and Gilberg, Frank and Schr{\"o}der, Manuela and Breuer, Andrea and Edler, Lutz and Wießler, Manfred}, title={Analysis of the inhibition of N-nitroso-dimethylamine activation in the liver by N-nitro-dimethylamine using a new non-linear statistical method}, year={1999}, pages={459-464}, language={eng}, issn={1460-2180}, volume={20}, number={3}, note={Gesehen am 04.02.2019}, journal={Carcinogenesis}, doi={10.1093/carcin/20.3.459}, } @article{UBHD-69081499, author={Funk, Dorothee and Schrenk, Hans-Hermann and Frei, Eva}, title={Development of a novel polyethylene glycol-corticosteroid-conjugate with an acid-cleavable linker}, year={2011}, pages={434-445}, language={eng}, issn={1029-2330}, volume={19}, number={6}, note={Gesehen am 01.06.2023 ; Online ver{\"o}ffentlicht: 02 Aug 2010}, journal={Journal of drug targeting}, doi={10.3109/1061186X.2010.504271}, } @article{UBHD-68950376, author={Hodek, Petr and Krizkova, Jitka and Frei, Eva and Singh, Rajinder and Arlt, Volker M. and Stiborová, Marie}, title={Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens}, year={2011}, pages={25-34}, language={eng}, issn={2354-4716}, volume={32}, number={Suppl. 1}, note={Gesehen am 04.08.2022}, journal={Neuroendocrinology letters}, } @article{UBHD-68637013, author={Hrabeta, Jan and Groh, Tomas and Khalil, Mohamed Ashraf and Poljakova, Jitka and Adam, Vojtech and Kizek, Rene and Uhlik, Jiri and Doktorova, Helena and Cerna, Tereza and Frei, Eva and Stiborova, Marie and Eckschlager, Tomas}, title={Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells}, year={2015}, pages={971-980}, language={eng}, issn={1791-2423}, volume={47}, number={3}, note={Gesehen am 14.09.2020}, journal={International journal of oncology}, doi={10.3892/ijo.2015.3066}, } @article{UBHD-68939208, author={Kotrbová, Věra and Mrázová, Barbora and Moserová, Michaela and Martínek, Václav and Hodek, Petr and Hudeček, Jiří and Frei, Eva and Stiborová, Marie}, title={Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy}, year={2011}, pages={669-680}, language={eng}, issn={1873-2968}, volume={82}, number={6}, note={Gesehen am 08.07.2022 ; Im Titel ist die Zahl 5 tiefgestellt}, journal={Biochemical pharmacology}, doi={10.1016/j.bcp.2011.06.003}, } @article{UBHD-68955688, author={Levová, Kateřina and Moserová, Michaela and Kotrbová, Věra and Šulc, Miroslav and Henderson, Colin J. and Wolf, C. Roland and Phillips, David H. and Frei, Eva and Schmeiser, Heinz and Mareš, Jaroslav and Arlt, Volker M. and Stiborová, Marie}, title={Role of pytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I}, subtitle={studies with the hepatic NADPH:Cytochrome P450 reductase null (HRN) mouse model}, year={2011}, pages={43-56}, language={eng}, issn={1096-0929}, volume={121}, number={1}, note={Gesehen am 19.08.2022}, journal={Toxicological sciences}, doi={10.1093/toxsci/kfr050}, } @article{UBHD-68590045, author={Liesenfeld, David and Habermann, Nina and Toth, Reka and Owen, Robert and Frei, Eva and B{\"o}hm, J{\"u}rgen and Schrotz-King, Petra and Klika, Karel D. and Ulrich, Cornelia}, title={Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare)}, year={2015}, pages={998-1012}, language={eng}, issn={1573-3890}, volume={11}, number={4}, note={Published online: 20 December 2014 ; Gesehen am 23.06.2020}, journal={Metabolomics}, doi={10.1007/s11306-014-0758-3}, } @article{UBHD-68952584, author={Martinek, Vaclav and Kubickova, Bozena and Arlt, Volker M. and Frei, Eva and Schmeiser, Heinz and Hudecek, Jiri and Stiborova, Marie}, title={Comparison of activation of aristolochic acid I and II with NADPH}, subtitle={quinone oxidoreductase, sulphotransferases and N-acetyltranferases}, year={2011}, pages={57-70}, language={eng}, issn={2354-4716}, volume={32}, number={1}, note={Gesehen am 11.08.2022}, journal={Neuroendocrinology letters}, } @article{UBHD-68966058, author={Naiman, Karel and Martínková, Markéta and Schmeiser, Heinz and Frei, Eva and Stiborová, Marie}, title={Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity}, year={2011}, pages={160-168}, language={eng}, issn={1388-2120}, volume={726}, number={2}, note={Gesehen am 21.09.2022}, journal={Mutation research}, doi={10.1016/j.mrgentox.2011.09.010}, } @article{UBHD-69071494, author={Naiman, Karel and Hodek, Petr and Liberda, Jiří and Schmeiser, Heinz and Frei, Eva and Stiborová, Marie}, title={Rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans}, year={2010}, pages={1229-1247}, language={eng}, issn={1212-6950}, volume={75}, number={12}, note={Gesehen am 03.05.2023}, journal={Collection of Czechoslovak chemical communications}, doi={10.1135/cccc2010077}, } @article{UBHD-69074987, author={Neumann, Elena and Frei, Eva and Funk, Dorothee and Becker, Matthias D and Schrenk, Hans-Hermann and M{\"u}ller-Ladner, Ulf and Fiehn, Christoph}, title={Native albumin for targeted drug delivery}, year={2010}, pages={915-925}, language={eng}, issn={1744-7593}, volume={7}, number={8}, note={Gesehen am 12.05.2023}, journal={Expert opinion on drug delivery}, doi={10.1517/17425247.2010.498474}, } @article{UBHD-69001341, author={Poljakova, Jitka and Hrebackova, Jana and Dvorakova, Marketa and Moserova, Michaela and Eckschlager, Tomas and Hrabeta, Jan and G{\"o}ttlicherova, Marketa and Kopejtkova, Barbora and Frei, Eva and Kizek, Rene and Stiborova, Marie}, title={Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma}, year={2011}, pages={101-116}, language={eng}, issn={2354-4716}, volume={32}, number={Suppl 1}, note={Gesehen am 03.01.2023}, journal={Neuroendocrinology letters}, } @article{UBHD-68354678, author={Schneider, Thomas and Frei, Eva and Wießler, Manfred}, title={The profile of urinary metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats is determined by its pulmonary metabolism}, year={1999}, pages={247-266}, language={eng}, issn={1872-7786}, volume={118}, number={3}, note={Gesehen am 04.02.2019}, journal={Chemico-biological interactions}, doi={10.1016/S0009-2797(99)00083-6}, } @article{UBHD-68354147, author={Seimetz, Diane and Frei, Eva and Schn{\"o}lzer, Martina and Kempf, Tore and Wießler, Manfred}, title={One step isolation of bovine asialoglycoprotein receptor and its characterization by sequence analysis and MALDI mass spectrometry}, year={1999}, pages={115-124}, language={eng}, issn={1573-4935}, volume={19}, number={2}, note={Gesehen am 01.02.2019}, journal={Bioscience reports}, doi={10.1023/A:1020162527447}, } @article{UBHD-68706914, author={Souza, José R. R. de and Trevisan, Maria T.S. and Hull, William Edmund and W{\"u}rtele, Gerd and Breuer, Andrea and Frei, Eva and Ulrich, Cornelia and Owen, Robert}, title={Transformation of mangiferin to norathyriol by human fecal matrix in anaerobic conditions}, subtitle={comprehensive NMR of the xanthone metabolites, antioxidant capacity, and comparative cytotoxicity against vancer cell lines}, year={2020}, pages={1-9}, language={eng}, issn={1555-9475}, volume={15}, note={Gesehen am 06.05.2022}, journal={Natural product communications}, doi={10.1177/1934578X20910286}, } @article{UBHD-68590020, author={Stiborová, Marie and Černá, Věra and Moserová, Michaela and Mrízová, Iveta and Arlt, Volker M. and Frei, Eva}, title={The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies}, subtitle={studies with rats, hepatic cytochrome P450 reductase null (HRN™) mice and pure enzymes}, year={2015}, pages={284-306}, language={eng}, issn={1422-0067 and 1661-6596}, volume={16}, number={1}, note={Published: 25 December 2014 ; Gesehen am 23.06.2020}, journal={International journal of molecular sciences}, doi={10.3390/ijms16010284}, } @article{UBHD-68976984, author={Stiborová, Marie and Mareîs, Jaroslav and Frei, Eva and Arlt, Volker M. and Martinek, Vaclav and Schmeiser, Heinz}, title={The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H}, subtitle={quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases}, year={2011}, pages={448-459}, language={eng}, issn={1098-2280}, volume={52}, number={6}, note={Gesehen am 21.10.2022}, journal={Environmental and molecular mutagenesis}, doi={10.1002/em.20642}, } @article{UBHD-68590011, author={Stiborová, Marie and Bárta, František and Levová, Kateřina and Hodek, Petr and Frei, Eva and Arlt, Volker M. and Schmeiser, Heinz H.}, title={The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats}, year={2015}, pages={2141-2158}, language={eng}, issn={1432-0738}, volume={89}, number={11}, note={Published online: 11 September 2014 ; Gesehen am 23.06.2020}, journal={Archives of toxicology}, doi={10.1007/s00204-014-1360-1}, } @article{UBHD-68976988, author={Stiborová, Marie and Mares, Jaroslav and Levova, Kateřina and Pavlickova, Jana and Barta, Frantisek and Hodek, Petr and Frei, Eva and Schmeiser, Heinz}, title={Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I}, subtitle={evidence of their contribution to aristolochic acid I detoxication and activation in rat liver}, year={2011}, pages={121-130}, language={eng}, issn={2354-4716}, volume={32}, number={1}, note={Gesehen am 21.10.2022}, journal={Neuroendocrinology letters}, } @article{UBHD-68353383, author={Weigand, Martina and Frei, Eva and Graf, N. and Buchholz, B. and Wolfrom, C. and Breuer, Andrea and Wießler, Manfred}, title={Mechanisms of resistance to methotrexate in childhood acute lymphoblastic leukemia}, subtitle={circumvention of thymidylate synthase inhibition}, year={1999}, pages={513-519}, language={eng}, issn={1432-1335}, volume={125}, number={8}, note={Gesehen am 30.01.2019}, journal={Journal of cancer research and clinical oncology}, doi={10.1007/s004320050310}, }