Biosimilars of monoclonal antibodies

• Titel: Biosimilars of monoclonal antibodies
• Titelzusatz: a practical guide to manufracturing, preclinical, and clinical development
• Mitwirkende: Liu, Cheng [HerausgeberIn]
• Mitwirkende: Morrow, K. John [HerausgeberIn]
• Mitwirkende: Morrow, K. John Jr. [HerausgeberIn]
• Verf.angabe: edited by Cheng Liu (Ph.D.), K. John Morrow, Jr. (Ph.D.)
• Verlagsort: Hoboken, New Jersey
• Verlag: Wiley
• E-Jahr: 2017
• Jahr: [2017]
• Umfang: lii, 652 Seiten
• Illustrationen: Illustrationen
• Fussnoten: Literaturangaben
• ISBN: 978-1-118-66231-1
• Schlagwörter: (s)Antikörper / (s)Therapie
• Sprache: eng
• Bibliogr. Hinweis: Erscheint auch als : Online-Ausgabe |(DE-576)BSZ485066920
• RVK-Notation: WF 9900
• K10plus-PPN: 834995301

Abstract

The history of therapeutic monoclonal antibodies / Regis Sodoyer -- Structure, classification and naming of therapeutic monoclonal antibodies / Zhinan Xia -- Mechanism of action for therapeutic antibodies / Yu Zhou and James D. Marks -- Therapeutic monoclonal antibodies and their targets / Maurizio Chiriva-Internati, et al -- Antibody post-translational modifications / Roy Jefferis -- The pharmacology, pharmacokinetics, and pharmacodynamics of antibodies / Ningning Xu, Meimei Liu, Margaret Liu -- Monoclonal antibodies : applications in clinical oncology / Jeanene ("Gigi") Robison -- Development of biosimilar rituximab and clinical experience / Reena Nair -- Monoclonal antibodies for infectious diseases / Steven J. Projan -- Monoclonal antibodies for musculoskeletal, CNS, and other diseases / Junming Yie and Tao Wu -- Manufacture of recombinant therapeutic proteins using chinese hamster ovary cells in large-scale bioreactors : history, methods and perspectives / Florian M. Wurm and Maria De Jesus -- Process development / Samuel D. Stimple and David W. Wood -- Biosimilars and biobetters : impact on biopharmaceutical manufacturing and CMOs / Ronald A. Rader -- Cell line and cell culture development for biosimilar antibody drug manufacturing / Jianguo Yang -- Product analysis of biosimilar antibodies / Weidong Jiang, Scott Liu and Ziyang Zhong -- Bioanalytical development / Rafiq Islam -- Preclinical and clinical development of biosimilar antibodies / João Eurico Fonseca and João Gonçalves -- Regulatory issues / Clarinda Islam -- Legal considerations / K. Lance Anderson, Jennifer R. Moore Meline, and Jonathan D. Ball -- ADCC enhancement technologies for next generation therapeutic antibodies / Cheng Liu and Su Yan -- Biosimilar antibody half-life : engineering for optimal performance / K. John Morrow, Jr -- Technologies for antibody drug conjugation / Patrick G. Holder and David Rabuka