Signaling pathways and axis formation in the lower metazoa

• Verfasst von: Holstein, Thomas W. [VerfasserIn]
• Verfasst von: Watanabe, Hiroshi [VerfasserIn]
• Verfasst von: Özbek, Suat [VerfasserIn]
• Titel: Signaling pathways and axis formation in the lower metazoa
• Verf.angabe: Thomas W. Holstein, Hiroshi Watanabe, Suat Özbek
• Umfang: 41 S.
• Fussnoten: Gesehen am 16.02.2017
• Titel Quelle: Enthalten in: Growth factors in development
• Jahr Quelle: 2011
• Band/Heft Quelle: (2011), S. 137-177
• ISBN Quelle: 978-0-12-385975-4
• ISBN Quelle: 0-12-385975-1
• ISBN Quelle: 978-0-12-385976-1
• ISBN Quelle: 0-12-385976-X
• DOI: doi:10.1016/B978-0-12-385975-4.00012-7
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1553512243

Abstract

The determination of the body axis in the last common ancestor of bilaterian animals is still a matter of debate. While Hox genes pattern the formation of the primary, anteroposterior body axis in bilaterians, there is growing evidence from lower metazoans that the Wnt/β-catenin pathway acts as the primordial signaling system in this process. This review summarizes molecular data from recent genomic analyses of basal model organisms with a focus on the evolution of signaling pathways involved in the establishment of the primary and successive body axes during early metazoan evolution.