The V-ATPase

• Verfasst von: Schumacher, Karin [VerfasserIn]
• Verfasst von: Krebs, Melanie [VerfasserIn]
• Titel: The V-ATPase
• Titelzusatz: small cargo, large effects
• Verf.angabe: Karin Schumacher, Melanie Krebs
• Umfang: 7 S.
• Fussnoten: Gesehen am 10.05.2017
• Titel Quelle: Enthalten in: Current opinion in plant biology
• Jahr Quelle: 2010
• Band/Heft Quelle: 13(2010), 6, S. 724-730
• ISSN Quelle: 1879-0356
• DOI: doi:10.1016/j.pbi.2010.07.003
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1558410414

Abstract

About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated research on the plant vacuolar-type H+-ATPase (V-ATPase, VHA). Since, it has been firmly established that these complex molecular machines are essential for what can be defined as cellular logistics. In a eukaryotic cell, the flow of goods between compartments is achieved either by protein-mediated membrane transport or via vesicular trafficking. Over the past years, it has become increasingly clear that V-ATPases do not only energize secondary active transport but are also important regulators of membrane trafficking.