Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Tomer, Raju [VerfasserIn]  |
| Denes, Alexandru S. [VerfasserIn]  |
| Tessmar-Raible, Kristin [VerfasserIn]  |
| Arendt, Detlev [VerfasserIn]  |
Titel: | Profiling by image registration reveals common origin of Annelid mushroom bodies and vertebrate pallium |
Verf.angabe: | Raju Tomer, Alexandru S. Denes, Kristin Tessmar-Raible, Detlev Arendt |
Umfang: | 10 S. |
Fussnoten: | Gesehen am 23.05.2017 |
Titel Quelle: | Enthalten in: Cell |
Jahr Quelle: | 2010 |
Band/Heft Quelle: | 142(2010), 5, S. 800-809 |
ISSN Quelle: | 1097-4172 |
Abstract: | Summary The evolution of the highest-order human brain center, the “pallium” or “cortex,” remains enigmatic. To elucidate its origins, we set out to identify related brain parts in phylogenetically distant animals, to then unravel common aspects in cellular composition and molecular architecture. Here, we compare vertebrate pallium development to that of the mushroom bodies, sensory-associative brain centers, in an annelid. Using a newly developed protocol for cellular profiling by image registration (PrImR), we obtain a high-resolution gene expression map for the developing annelid brain. Comparison to the vertebrate pallium reveals that the annelid mushroom bodies develop from similar molecular coordinates within a conserved overall molecular brain topology and that their development involves conserved patterning mechanisms and produces conserved neuron types that existed already in the protostome-deuterostome ancestors. These data indicate deep homology of pallium and mushroom bodies and date back the origin of higher brain centers to prebilaterian times. |
DOI: | doi:10.1016/j.cell.2010.07.043 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Kostenfrei: Verlag: http://dx.doi.org/10.1016/j.cell.2010.07.043 |
| Kostenfrei: Verlag: http://www.sciencedirect.com/science/article/pii/S0092867410008913 |
| DOI: https://doi.org/10.1016/j.cell.2010.07.043 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1558925414 |
Verknüpfungen: | → Zeitschrift |
Profiling by image registration reveals common origin of Annelid mushroom bodies and vertebrate pallium / Tomer, Raju [VerfasserIn] (Online-Ressource)
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