Status: Bibliographieeintrag
Standort: ---
Exemplare:
---
| Online-Ressource |
Verfasst von: | Triphan, Simon M. F. [VerfasserIn]  |
| Kauczor, Hans-Ulrich [VerfasserIn]  |
Titel: | Oxygen enhanced lung MRI by simultaneous measurement of T1 and T2* during free breathing using ultrashort TE |
Verf.angabe: | Simon M.F. Triphan, Dipl Phys, Felix A. Breuer, PhD, Daniel Gensler, Dipl Phys, Hans-Ulrich Kauczor, MD and Peter M. Jakob, PhD |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 07.06.2017 |
Titel Quelle: | Enthalten in: Journal of magnetic resonance imaging |
Jahr Quelle: | 2015 |
Band/Heft Quelle: | 41(2015), 6, S. 1708-1714 |
ISSN Quelle: | 1522-2586 |
Abstract: | Purpose: to provide a robust method for the simultaneous quantification of T1 and T2* in the human lung during free breathing. Breathing pure oxygen accelerates T1 and T2* relaxation in the lung. While T1 shortening reflects an increased amount of dissolved molecular oxygen in lung tissue, T2* shortening shows an increased concentration of oxygen in the alveolar gas. Therefore, both parameters reflect different aspects of the oxygen uptake and provide complementary lung functional information.Materials and Methods: a segmented inversion recovery Look-Locker multiecho sequence based on a multiecho 2D ultrashort TE (UTE) was employed for simultaneous T1 and T2* quantification. The radial projections follow a modified golden angle ordering, allowing for respiratory self-gating and thus the reconstruction of a series of differently T1 and T2*-weighted images in arbitrary breathing states. The method was evaluated in nine healthy volunteers while breathing room air and pure oxygen, with two volunteers examined at five oxygen concentrations. Results: relative differences of ΔT1 between 7.9% and 12.7% and of ΔT2* between 13.2% and 6.0% were found. Conclusion: the proposed method provides inherently coregistered, quantitative T1 and T2* maps in both expiration and inspiration from a single measurement acquired during free breathing and is thus well suited for clinical application.J. Magn. Reson. Imaging 2015;41:1708-1714. © 2014 Wiley Periodicals, Inc. |
DOI: | doi:10.1002/jmri.24692 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Verlag: http://dx.doi.org/10.1002/jmri.24692 |
| Verlag: http://onlinelibrary.wiley.com/doi/10.1002/jmri.24692/abstract |
| DOI: https://doi.org/10.1002/jmri.24692 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1559524103 |
Verknüpfungen: | → Zeitschrift |
Oxygen enhanced lung MRI by simultaneous measurement of T1 and T2* during free breathing using ultrashort TE / Triphan, Simon M. F. [VerfasserIn] (Online-Ressource)
68126153