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Verfasst von:Lorenzo Bermejo, Justo [VerfasserIn]   i
 Boekstegers, Felix [VerfasserIn]   i
 González Silos, Rosa [VerfasserIn]   i
 Barahona Ponce, Carol [VerfasserIn]   i
 Fischer, Christine [VerfasserIn]   i
 Peil, Barbara [VerfasserIn]   i
Titel:Subtypes of Native American ancestry and leading causes of death
Titelzusatz:Mapuche ancestry-specific associations with gallbladder cancer risk in Chile
Verf.angabe:Justo Lorenzo Bermejo, Felix Boekstegers, Rosa González Silos, Katherine Marcelain, Pablo Baez Benavides, Carol Barahona Ponce, Bettina Müller, Catterina Ferreccio, Jill Koshiol, Christine Fischer, Barbara Peil, Janet Sinsheimer, Macarena Fuentes Guajardo, Olga Barajas, Rolando Gonzalez-Jose, Gabriel Bedoya, Maria Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Andres Ruiz Linares, Francisco Rothhammer
E-Jahr:2017
Jahr:May 25, 2017
Umfang:23 S.
Fussnoten:Gesehen am 19.06.2017
Titel Quelle:Enthalten in: Public Library of SciencePLoS Genetics
Ort Quelle:San Francisco, Calif. : Public Library of Science, 2005
Jahr Quelle:2017
Band/Heft Quelle:13(2017,5), Artikel-Nummer e1006756, 23 Seiten
ISSN Quelle:1553-7404
Abstract:A lot of attention has been paid to Latino heterogeneity related to individual proportions of Native American, European and African ancestry. The importance of the type of Native American ancestry for health, however, has hardly been studied. Here we examined genetic data from 2,039 admixed Chileans to investigate possible associations between top causes of death and the two major types of Native American ancestry in Chile. Our findings demonstrate the necessity of suitable surrogates for ancestry estimation which mirror the actual composition of the study population, and the advantage of considering fine-scale Latino heterogeneity for unraveling of disease etiology and personalized healthcare.
DOI:doi:10.1371/journal.pgen.1006756
URL:kostenfrei: Volltext ; Verlag: http://dx.doi.org/10.1371/journal.pgen.1006756
 kostenfrei: Volltext: http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006756
 DOI: https://doi.org/10.1371/journal.pgen.1006756
Datenträger:Online-Ressource
Sprache:eng
Bibliogr. Hinweis:Forschungsdaten: Lorenzo Bermejo, Justo, 1972 - : Subtypes of Native American ancestry and leading causes of death
Sach-SW:Chile (country)
 Death rates
 Educational attainment
 Gallbladder cancer
 Genetics of disease
 Malignant skin neoplasms
 Native Americans
 Neoplasms
K10plus-PPN:1559826711
Verknüpfungen:→ Zeitschrift
 
 
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