Nocturnal sleep duration and cognitive impairment in a population-based study of older adults

• Verfasst von: Loerbroks, Adrian [VerfasserIn]
• Verfasst von: Amelang, Manfred [VerfasserIn]
• Verfasst von: Stürmer, Til [VerfasserIn]
• Titel: Nocturnal sleep duration and cognitive impairment in a population-based study of older adults
• Verf.angabe: Adrian Loerbroks, Desiree Debling, Manfred Amelang and Til Stürmer
• Jahr: 2010
• Umfang: 10 S.
• Fussnoten: Gesehen am 20.06.2017 ; Article was first published on 22 June 2009
• Titel Quelle: Enthalten in: International journal of geriatric psychiatry
• Ort Quelle: Chichester [u.a.] : Wiley, 1986
• Jahr Quelle: 2010
• Band/Heft Quelle: 25(2010), 1, Seite 100-109
• ISSN Quelle: 1099-1166
• DOI: doi:10.1002/gps.2305
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: cognition
• Sach-SW: east boston memory test
• Sach-SW: epidemiology
• Sach-SW: Germany
• Sach-SW: prevalence ratio
• Sach-SW: sleep duration
• Sach-SW: telephone interview for cognitive status
• K10plus-PPN: 1560015535

Abstract

Objective: We aimed to investigate the association between nocturnal sleep duration, changes in nocturnal sleep duration and cognitive impairment in older adults. Methods: 4010 participants of a population-based cohort study provided information on nocturnal sleep duration at baseline (1991-1995) and at follow-up (2002/2003). 792 follow-up participants aged 70+ by 2006 participated in telephone-based cognitive assessments. Several cognitive tests were used including the telephone interview for cognitive status (TICS). Cognitive impairment was defined as <31 points on the TICS (13.0%) and as below this percentile on the other tests. Based on individual tests, a verbal memory score and a total score were constructed. Multivariable prevalence ratios (PRs) of cognitive impairment and 95% confidence intervals (95%CIs) were computed using Poisson regression. Analyses were restricted to those free of depression in 2002/2003 (n = 695). Results: Sleeping ≤6 or 8 h per night (versus 7 h) were unrelated to cognitive impairment. Sleeping ≥9 h was positively, although imprecisely, associated with impairment of verbal memory (PR = 1.7, 95%CI = 1.0, 3.0), and less pronounced with the other cognitive measures. An increase in sleep duration from 7-8 h in 1992-1995 to ≥9 h 8.5 years later (versus sleeping 7-8 h at both time points) was associated with an increased prevalence of cognitive impairment according to the TICS (PR = 2.1, 95% = 1.0, 4.5) and the verbal memory score (PR = 2.0, 95%CI = 1.0, 3.8). Conclusions: Increases in sleep duration are associated with cognitive impairment. A biological explanation for this association is currently lacking. Increases in sleep duration could be a marker of cognitive deficits. Copyright © 2009 John Wiley & Sons, Ltd.