Possible pathogenic mechanism of propofol infusion syndrome Involves coenzyme q

• Verfasst von: Vanlander, Arnaud Vincent [VerfasserIn]
• Verfasst von: Okun, Jürgen G. [VerfasserIn]
• Titel: Possible pathogenic mechanism of propofol infusion syndrome Involves coenzyme q
• Verf.angabe: Arnaud Vincent Vanlander, M.D., Juergen Guenther Okun, Ph.D., Annick de Jaeger, M.D., Joél Smet, B.A.Sc., Elien De Latter, B.A.Sc., Boel De Paepe, Ph.D., Georges Dacremont, Ph.D., Birgitte Wuyts, M.D., Ph.D., Bert Vanheel, Ph.D., Peter De Paepe, M.D., Ph.D., Philippe Germaine Jorens, M.D., Ph.D., Niels Van Regenmortel, M.D., Rudy Van Coster, M.D., Ph.D.
• Jahr: 2015
• Jahr des Originals: 2014
• Umfang: 10 S.
• Fussnoten: Published online: September 4, 2014 ; Gesehen am 10.07.2017
• Titel Quelle: Enthalten in: Anesthesiology
• Ort Quelle: Hagerstown, Md. : Lippincott Williams & Wilkins, 1940
• Jahr Quelle: 2015
• Band/Heft Quelle: 122(2015), 2, Seite 343-352
• ISSN Quelle: 1528-1175
• DOI: doi:10.1097/ALN.0000000000000484
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1560668687

Abstract

Abstract Background: Propofol is a short-acting intravenous anesthetic agent. In rare conditions, a life-threatening complication known as propofol infusion syndrome can occur. The pathophysiologic mechanism is still unknown. Some studies suggested that propofol acts as uncoupling agent, others suggested that it inhibits complex I or ...