A study of enhanced ion formation from metal-semiconductor complexes in atmospheric pressure laser desorption/ionization mass spectrometry

• Verfasst von: Silina, Yuliya E. [VerfasserIn]
• Verfasst von: Herbeck-Engel, Petra [VerfasserIn]
• Verfasst von: Koch, Marcus [VerfasserIn]
• Titel: A study of enhanced ion formation from metal-semiconductor complexes in atmospheric pressure laser desorption/ionization mass spectrometry
• Institutionen: Leibniz-Institut für Neue Materialien [GeistigeR SchöpferIn]
• Verf.angabe: Yuliya E. Silina, Petra Herbeck-Engel and Marcus Koch
• Jahr: 2017
• Jahr des Originals: 2016
• Umfang: 11 S.
• Fussnoten: Published online: 16 November 2016 ; Gesehen am 24.07.2017
• Titel Quelle: Enthalten in: Journal of mass spectrometry
• Ort Quelle: Bognor Regis [u.a.] : Wiley, 1995
• Jahr Quelle: 2017
• Band/Heft Quelle: 52(2017), 1, Seite 43-53
• ISSN Quelle: 1096-9888
• DOI: doi:10.1002/jms.3898
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: analyte attachment
• Sach-SW: hybrid metal-semiconductor target
• Sach-SW: milk screening
• Sach-SW: polymorphism
• Sach-SW: SALDI-MS
• K10plus-PPN: 156113550X

Abstract

The study of the key parameters impacted surface-assisted laser desorption/ionization-mass spectrometry is of broad interest. In previous studies, it has been shown that surface-assisted laser desorption/ionization-mass spectrometry is a complex process depending on multiple factors. In the presented study, we showed that neither porosity, light absorbance nor surface hydrophobicity alone influence the enhancement phenomena observed from the hybrid metal-semiconductor complexes versus individual targets, but small changes in the analyte attaching to the target significantly affect laser desorption ionization-efficiency. By means of Raman spectroscopy and scanning electron microscopy, it was revealed that the formation of an amorphous analyte layer after drying on a solid substrate was essential for the enhanced laser desorption ionization-signal observed from the hybrid metal-semiconductor targets, and the crystallization properties of the analyte appeared as a function of the substrate. Obtained results were used for the screening of regular and lactose-free milk samples through the hybrid metal-semiconductor target. Copyright © 2016 John Wiley & Sons, Ltd.