When yeast cells meet, karyogamy!

• Verfasst von: Gibeaux, Romain [VerfasserIn]
• Verfasst von: Knop, Michael [VerfasserIn]
• Titel: When yeast cells meet, karyogamy!
• Titelzusatz: an example of nuclear migration slowly resolved
• Verf.angabe: Romain Gibeaux, and Michael Knop
• E-Jahr: 2013
• Jahr: 2013 May 1
• Umfang: 7 S.
• Fussnoten: Gesehen am 10.08.2017
• Titel Quelle: Enthalten in: Nucleus
• Ort Quelle: Austin, Tex. : Landes Bioscience, 2010
• Jahr Quelle: 2013
• Band/Heft Quelle: 4(2013), 3, Seite 182-188
• ISSN Quelle: 1949-1042
• DOI: doi:10.4161/nucl.25021
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Saccharomyces cerevisiae
• Sach-SW: Saccharomyces cerevisiae Proteins
• Sach-SW: Animals
• Sach-SW: Kar3
• Sach-SW: karyogamy
• Sach-SW: nuclear migration
• Sach-SW: spindle pole body
• Sach-SW: Cell Nucleus
• Sach-SW: Diploidy
• Sach-SW: Gene Expression Regulation, Fungal
• Sach-SW: Kinesin
• Sach-SW: kinesin-14
• Sach-SW: microtubule dynamics
• Sach-SW: microtubule motor protein
• Sach-SW: Microtubule Proteins
• Sach-SW: Microtubule-Associated Proteins
• Sach-SW: Microtubules
• Sach-SW: Models, Biological
• Sach-SW: nuclear fusion
• Sach-SW: yeast cell morphogenesis
• K10plus-PPN: 1562316095

Abstract

Cytoskeleton-mediated transport processes are central to the subcellular organization of cells. The nucleus constitutes the largest organelle of a cell, and studying how it is positioned and moved around during various types of cell morphogenetic processes has puzzled researchers for a long time. Now, the molecular architectures of the underlying dynamic processes start to reveal their secrets. In yeast, karyogamy denotes the migration of two nuclei toward each other-termed nuclear congression-upon partner cell mating and the subsequent fusion of these nuclei to form a diploid nucleus. It constitutes a well-studied case. Recent insights completed the picture about the molecular processes involved and provided us with a comprehensive model amenable to quantitative computational simulation of the process. This review discusses our understanding of yeast nuclear congression and karyogamy and seeks to explain how a detailed, quantitative and systemic understanding has emerged from this knowledge.