Status: Bibliographieeintrag
Standort: ---
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| Online-Ressource |
Verfasst von: | Moreno Borchart, Alexandra C. [VerfasserIn]  |
| Knop, Michael [VerfasserIn]  |
Titel: | Prospore membrane formation linked to the leading edge protein (LEP) coat assembly |
Verf.angabe: | Alexandra C. Moreno‐Borchart, Katrin Strasser, Martin G Finkbeiner, Anna Shevchenko, Andrej Shevchenko, Michael Knop |
Umfang: | 12 S. |
Fussnoten: | Gesehen am 25.08.2017 |
Titel Quelle: | Enthalten in: European Molecular Biology Organization: The EMBO journal |
Jahr Quelle: | 2001 |
Band/Heft Quelle: | 20(2001), 24, S. 6946-6957 |
ISSN Quelle: | 1460-2075 |
Abstract: | In yeast, the differentiation process at the end of meiosis generates four daughter cells inside the boundaries of the mother cell. A meiosis-specific plaque (MP) at the spindle pole bodies (SPBs) serves as the starting site for the formation of the prospore membranes (PSMs) that are destined to encapsulate the post-meiotic nuclei. Here we report the identification of Ady3p and Ssp1p, which are functional components of the leading edge protein (LEP) coat, that covers the ring-shaped opening of the PSMs. Ssp1p is required for the assembly of the LEP coat, which consists of at least three proteins (Ssp1p, Ady3p and Don1p). The assembly of the LEP coat starts with the formation of cytosolic precursors, which then bind in an Ady3p-dependent manner to the SPBs. Subsequent processes at the SPBs leading to functional LEP coats require Ssp1p and the MP components. During growth of the PSMs, the LEP coat functions in formation of the cup-shaped membrane structure that is indispensablefor the regulated cellularization of the cytoplasm around the post-meiotic nuclei. |
DOI: | doi:10.1093/emboj/20.24.6946 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Kostenfrei: Verlag: http://dx.doi.org/10.1093/emboj/20.24.6946 |
| DOI: https://doi.org/10.1093/emboj/20.24.6946 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1562743287 |
Verknüpfungen: | → Zeitschrift |
Prospore membrane formation linked to the leading edge protein (LEP) coat assembly / Moreno Borchart, Alexandra C. [VerfasserIn] (Online-Ressource)
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