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Verfasst von:Cury, Claire [VerfasserIn]   i
 Banaschewski, Tobias [VerfasserIn]   i
 Flor, Herta [VerfasserIn]   i
 Poustka, Luise [VerfasserIn]   i
Titel:Incomplete Hippocampal Inversion
Titelzusatz:A Comprehensive MRI Study of Over 2000 Subjects
Verf.angabe:Claire Cury, Roberto Toro, Fanny Cohen, Clara Fischer, Amel Mhaya, Jorge Samper-González, Dominique Hasboun, Jean-François Mangin, Tobias Banaschewski, Arun L. W. Bokde, Uli Bromberg, Christian Buechel, Anna Cattrell, Patricia Conrod, Herta Flor, Juergen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Hervé Lemaitre, Jean-Luc Martinot, Frauke Nees, Marie-Laure Paillère Martinot, Dimitri P. Orfanos, Tomas Paus, Luise Poustka, Michael N. Smolka, Henrik Walter, Robert Whelan, Vincent Frouin, Gunter Schumann, Joan A. Glaunès, Olivier Colliot and The IMAGEN Consortium
E-Jahr:2015
Jahr:22December2015
Umfang:12 S.
Fussnoten:Gesehen am 06.09.2017
Titel Quelle:Enthalten in: Frontiers in neuroanatomy
Ort Quelle:Lausanne : Frontiers Research Foundation, 2007
Jahr Quelle:2015
Band/Heft Quelle:9(2015) Artikel-Nummer 160, 12 Seiten
ISSN Quelle:1662-5129
Abstract:The incomplete-hippocampal-inversion (IHI), also known as malrotation, is an atypical anatomical pattern of the hippocampus, which has been reported in healthy subjects in different studies. However, extensive characterization of IHI in a large sample has not yet been performed. Furthermore, it is unclear whether IHI are restricted to the medial-temporal lobe or are associated with more extensive anatomical changes. Here, we studied the characteristics of IHI in a community-based sample of 2008 subjects of the IMAGEN database and their association with extra-hippocampal anatomical variations. The presence of IHI was assessed on T1-weighted anatomical magnetic resonance imaging (MRI) using visual criteria. We assessed the association of IHI with other anatomical changes throughout the brain using automatic morphometry of cortical sulci. We found that IHI were much more frequent in the left hippocampus (left: 17%, right: 6%, χ2-test, p<10-28). Compared to subjects without IHI, subjects with IHI displayed morphological changes in several sulci located mainly in the limbic lobe. Our results demonstrate that IHI are a common left-sided phenomenon in normal subjects and that they are associated with morphological changes outside the medial temporal lobe.
DOI:doi:10.3389/fnana.2015.00160
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: http://dx.doi.org/10.3389/fnana.2015.00160
 kostenfrei: Volltext: http://journal.frontiersin.org/article/10.3389/fnana.2015.00160/full
 DOI: https://doi.org/10.3389/fnana.2015.00160
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Anatomical variability
 Brain Development
 Cortical sulci
 Human hippocampus
 IHI
 IMAGEN database
 Malrotation
 Morphological changes
 normal brain
K10plus-PPN:1563270692
Verknüpfungen:→ Zeitschrift

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