| |  Online-Ressource |
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| Verfasst von: | Santos, Edgar [VerfasserIn]  |
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| | Léon, Fiorella [VerfasserIn] |
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| | Silos, Humberto [VerfasserIn] |
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| | Sánchez-Porras, Renán [VerfasserIn] |
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| | Unterberg, Andreas [VerfasserIn] |
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| | Sakowitz, Oliver [VerfasserIn] |
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| Titel: | Incidence, hemodynamic, and electrical characteristics of spreading depolarization in a swine model are affected by local but not by intravenous application of magnesium |
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| Verf.angabe: | Edgar Santos, Fiorella León, Humberto Silos, Renan Sanchez-Porras, C William Shuttleworth, Andreas Unterberg and Oliver W Sakowitz |
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| E-Jahr: | 2016 |
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| Jahr: | September 28, 2016 |
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| Fussnoten: | Gesehen am 10.10.2017 |
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| Titel Quelle: | Enthalten in: Journal of cerebral blood flow & metabolism |
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| Ort Quelle: | Thousands Oaks, Calif. : Sage, 1981 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 36(2016), 12, Seite 2051-2057$77 |
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| ISSN Quelle: | 1559-7016 |
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| Abstract: | The aim was to characterize the effects of magnesium sulfate, using i.v. bolus and local administration, using intrinsic signal imaging, and on electrocorticographic activity during the induction and propagation of spreading depolarizations in the gyrencephalic porcine brain. Local application of magnesium sulfate led to a complete inhibition of spreading depolarizations. One hour after washing out the topical magnesium sulfate, re-incidence of the spreading depolarizations was observed in 50% of the hemispheres. Those spreading depolarizations showed attenuation in hemodynamic characteristics and speed in intrinsic optical signal imaging. The electrical amplitude decreased through electrocorticographic activity. Intravenous magnesium therapy showed no significant effects on spreading depolarization incidence and characteristics. |
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| DOI: | doi:10.1177/0271678X16671317 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: http://dx.doi.org/10.1177/0271678X16671317 |
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| | Volltext: https://doi.org/10.1177/0271678X16671317 |
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| | DOI: https://doi.org/10.1177/0271678X16671317 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1564252426 |
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| Verknüpfungen: | → Zeitschrift |
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Incidence, hemodynamic, and electrical characteristics of spreading depolarization in a swine model are affected by local but not by intravenous application of magnesium / Santos, Edgar [VerfasserIn]; September 28, 2016 (Online-Ressource)
