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Status: Bibliographieeintrag

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Verfasst von:Schuster, Alexander K. [VerfasserIn]   i
 Fischer, Joachim E. [VerfasserIn]   i
 Voßmerbäumer, Urs [VerfasserIn]   i
Titel:A retinal snap shot may indicate individual risk for cardiovascular disease
Titelzusatz:the MIPH Eye and Health Study
Verf.angabe:Alexander Karl-Georg Schuster, Joachim Ernst Fischer, Urs Vossmerbaeumer
E-Jahr:2015
Jahr:1 February 2015
Umfang:4 S.
Fussnoten:Gesehen am 26.10.2017
Titel Quelle:Enthalten in: International journal of cardiology
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 1981
Jahr Quelle:2015
Band/Heft Quelle:180(2015), Seite 30-33
ISSN Quelle:1874-1754
Abstract:Examination of retinal vasculature can be used to non-invasively quantify changes within the microvasculature of the human body and might be a predictor of cardiovascular disease. This study evaluates associations of the structure of the retinal vasculature with established risk factors for cardiovascular disease. A cross-sectional study was performed in a working age population. Several systemic cardiovascular parameters were analyzed and PROCAM- and SCORE-risk estimates were calculated. A quantitative ophthalmological examination including digital fundus imaging has taken place. Central retinal arterial/venous equivalents (CRAE/CRVE) and arterio-venous ratio (AVR) were analyzed using validated software. Associations of retinal vessel parameters and systemic cardiovascular and ocular parameters were calculated by multivariate analysis using SPSS software. A p-value of <0.05 with Bonferroni correction was accepted as significant. 338 probands were included. A smaller CRAE was independently associated with increased mean arterial blood pressure, higher age and higher body-mass index. Regarding CRVE age was inversely associated. Other cardiovascular risk parameters were not associated to the examined retinal vessel equivalents. AVR showed a significant association to mean arterial blood pressure and body-mass-index. PROCAM- and SCORE-risk estimates were negatively associated with CRAE and AVR, but not associated to CRVE. Arterial retinal vessel analysis and AV-ratio showed associations to established cardiovascular parameters in the study population. PROCAM- and SCORE-risk estimates as indicators of cardiovascular risk were associated with the CRAE and the AV-ratio. This suggests that a single snap shot of the retinal vessels may indicate the individual relative risk for cardiovascular events.
DOI:doi:10.1016/j.ijcard.2014.11.015
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1016/j.ijcard.2014.11.015
 Volltext: http://www.sciencedirect.com/science/article/pii/S0167527314021573
 DOI: https://doi.org/10.1016/j.ijcard.2014.11.015
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:AV-ratio
 Cardiovascular risk factor
 Fundus photography
 PROCAM
 Refraction
 retinal vessel
 SCORE
K10plus-PPN:1564799743
Verknüpfungen:→ Zeitschrift

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