Comparison of four different collateral scores in acute ischemic stroke by CT angiography

• Verfasst von: Seker, Fatih [VerfasserIn]
• Verfasst von: Potreck, Arne [VerfasserIn]
• Verfasst von: Möhlenbruch, Markus Alfred [VerfasserIn]
• Verfasst von: Bendszus, Martin [VerfasserIn]
• Verfasst von: Pham, Mirko [VerfasserIn]
• Titel: Comparison of four different collateral scores in acute ischemic stroke by CT angiography
• Verf.angabe: Fatih Seker, Arne Potreck, Markus Möhlenbruch, Martin Bendszus, Mirko Pham
• Jahr: 2016
• Jahr des Originals: 2015
• Umfang: 4 S.
• Fussnoten: Published online first 9 December 2015 ; Gesehen am 06.11.2017
• Titel Quelle: Enthalten in: Journal of neuroInterventional surgery
• Ort Quelle: London : BMJ Journals, 2009
• Jahr Quelle: 2016
• Band/Heft Quelle: 8(2016), 11, Seite 1116-1118
• ISSN Quelle: 1759-8486
• DOI: doi:10.1136/neurintsurg-2015-012101
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1565020782

Abstract

Purpose: Multiple scores have been described for the assessment of collateralization in acute ischemic stroke. Currently, there is no gold standard for collateral assessment by CT angiography (CTA). This study compared four frequently used collateral scores with regard to their correlation with early infarct core and mismatch ratio. Methods: 30 consecutive patients with acute occlusion of the M1 segment or terminal carotid artery were reviewed retrospectively. Collaterals were assessed using dynamic and also single-phase CTA according to grading systems by the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR), Alberta Stroke Program Early CT Score (ASPECTS) (on collaterals), Christoforidis et al and Miteff et al. The Christoforidis and ASITN/SIR scores, which were initially designed for conventional angiography, were adapted to be applicable to CTA. The scores were compared with respect to early infarct core and mismatch ratio in perfusion CT estimated by RAPID software using Spearman correlation. Results: ASITN/SIR and ASPECTS collateral scores showed good correlation with early infarct core (rho=-0.696, p<0.001 and rho=-0.677, p<0.001) and mismatch ratio (rho=0.609, p<0.001 and rho=0.581, p<0.001). In contrast, the Christoforidis and Miteff scores correlated less well with infarct core (rho=0.245, p=0.191 and rho=-0.272, p=0.145, respectively) and mismatch ratio (rho=-0.329, p=0.075 and rho=0.279, p=0.135, respectively). ASPECTS and ASITN/SIR showed excellent cross-correlation (rho=0.901, p<0.001). Conclusions: Compared with the Christoforidis and Miteff scores, the modified ASITN/SIR and ASPECTS collateral scores showed consistently higher correlation with the extent of early infarct core and mismatch volume. This is probably because these scores evaluate the extent and delay of vascular enhancement in the affected territory rather than the backflow of contrast medium to the occlusion.