| Online-Ressource |
Verfasst von: | Mutters, Nico T. [VerfasserIn]  |
| Bieber, Christian Paul [VerfasserIn]  |
| Hauck, Catherine [VerfasserIn]  |
| Malek, Veronika [VerfasserIn]  |
| Frank, Uwe [VerfasserIn]  |
Titel: | Comparison of livestock-associated and health care-associated MRSA |
Titelzusatz: | genes, virulence, and resistance |
Verf.angabe: | Nico T. Mutters, Christian P. Bieber, Catherine Hauck, Gerald Reiner, Veronika Malek, Uwe Frank |
E-Jahr: | 2016 |
Jahr: | 26 August 2016 |
Umfang: | 5 S. |
Teil: | volume:86 |
| year:2016 |
| number:4 |
| pages:417-421 |
| extent:5 |
Fussnoten: | Gesehen am 05.12.2017 |
Titel Quelle: | Enthalten in: Diagnostic microbiology and infectious disease |
Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1983 |
Jahr Quelle: | 2016 |
Band/Heft Quelle: | 86(2016), 4, Seite 417-421 |
ISSN Quelle: | 1879-0070 |
Abstract: | Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) may colonize and infect humans with close contact to pigs. We compared phenotypic and genotypic differences in resistance and virulence of LA-MRSA isolates from farms and farmers with hospital-acquired methicillin-resistant S. aureus (HA-MRSA) and assessed carriage rates. Samples from pigs (n=330), occupationally exposed personnel (n=63), the farm environment (n=134), and hospital patients (n=220) were obtained. Approximately 50% (166/330) of pigs were MRSA positive. All LA-MRSA were resistant to tetracycline, compared to only 8% of HA-MRSA (P<0.001). In contrast, HA-MRSA isolates showed significantly higher resistance rates to quinolones (81% versus 7%; P<0.001). All strains isolated from occupationally exposed personnel (61.9%; 39/63) belonged to CC398. HA-MRSA isolates were diversely distributed, with predominance of CC5 (62.7%). Human strains carried significantly more virulence genes than porcine strains, especially exotoxins (P<0.001) and immune-evasion cluster genes (P<0.001). There were significant differences in resistance patterns and recognized genotypic virulence loci between LA-MRSA and HA-MRSA. |
DOI: | doi:10.1016/j.diagmicrobio.2016.08.016 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: http://dx.doi.org/10.1016/j.diagmicrobio.2016.08.016 |
| Volltext: http://www.sciencedirect.com/science/article/pii/S0732889316302553 |
| DOI: https://doi.org/10.1016/j.diagmicrobio.2016.08.016 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | CC398 |
| Genotyping |
| Infection control |
| Livestock |
| MRSA |
| Pig farms |
| Transmission |
K10plus-PPN: | 1566054885 |
Verknüpfungen: | → Zeitschrift |
Comparison of livestock-associated and health care-associated MRSA / Mutters, Nico T. [VerfasserIn]; 26 August 2016 (Online-Ressource)