Choroidal physiology and primary angle closure disease

• Verfasst von: Zhang, Xiulan [VerfasserIn]
• Verfasst von: Jonas, Jost B. [VerfasserIn]
• Titel: Choroidal physiology and primary angle closure disease
• Verf.angabe: Xiulan Zhang, Wei Wang, Tin Aung, Jost B. Jonas, Ningli Wang
• E-Jahr: 2015
• Jahr: November-December 2015
• Umfang: 10 S.
• Fussnoten: Gesehen am 13.12.2017
• Titel Quelle: Enthalten in: Survey of ophthalmology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1975
• Jahr Quelle: 2015
• Band/Heft Quelle: 60(2015), 6, Seite 547-556
• ISSN Quelle: 1879-3304
• DOI: doi:10.1016/j.survophthal.2015.06.005
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: angle-closure glaucoma
• Sach-SW: choroidal thickness
• Sach-SW: glaucoma
• Sach-SW: optical coherence tomography
• Sach-SW: pathogenesis
• K10plus-PPN: 156635952X

Abstract

Primary angle closure disease (PACD), prevalent in Asian countries, is generally associated with a shallower anterior chamber, a shorter axial length, thicker lens, hyperopia, and female sex. Other physiologic factors, however, may be important, especially with regard to triggering acute primary angle closure. Thickening of the choroid has been demonstrated in untreated and treated, acute and chronic PACD eyes. Recently, there has been growing interest in studying the role of the choroid in the pathophysiology of PACD. The emergence of new imaging technology such as the enhanced depth imaging mode of spectral-domain optical coherence tomography and swept-source optical coherence tomography has contributed to understanding PACD pathologies. We summarize the functions of the choroid and choroidal changes in the pathogenesis of PACD, and discuss potential future developments.