Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Konstantinides, Stavros [VerfasserIn]   i
 Grünig, Ekkehard [VerfasserIn]   i
Titel:Late outcomes after acute pulmonary embolism
Titelzusatz:rationale and design of FOCUS, a prospective observational multicenter cohort study
Verf.angabe:Stavros V. Konstantinides, Stefano Barco, Stephan Rosenkranz, Mareike Lankeit, Matthias Held, Felix Gerhardt, Leonard Bruch, Ralf Ewert, Martin Faehling, Julia Freise, Hossein-Ardeschir Ghofrani, Ekkehard Grünig, Michael Halank, Nadine Heydenreich, Marius M. Hoeper, Hanno H. Leuchte, Eckhard Mayer, F. Joachim Meyer, Claus Neurohr, Christian Opitz, Antonio Pinto, Hans-Jürgen Seyfarth, Rolf Wachter, Bianca Zäpf, Heinrike Wilkens, Harald Binder, Philipp S. Wild
E-Jahr:2016
Jahr:30 August 2016
Umfang:10 S.
Fussnoten:Gesehen am 18.12.2017
Titel Quelle:Enthalten in: Journal of thrombosis and thrombolysis
Ort Quelle:Dordrecht [u.a.] : Springer Science + Business Media B.V, 1994
Jahr Quelle:2016
Band/Heft Quelle:42(2016), 4, Seite 600-609
ISSN Quelle:1573-742X
Abstract:Acute pulmonary embolism (PE) is a frequent cause of death and serious disability. The risk of PE-associated mortality and morbidity extends far beyond the acute phase of the disease. In earlier follow-up studies, as many as 30 % of the patients died during a follow-up period of up to 3 years, and up to 50 % of patients continued to complain of dyspnea and/or poor physical performance 6 months to 3 years after the index event. The most feared 'late sequela' of PE is chronic thromboembolic pulmonary hypertension (CTEPH), the true incidence of which remains obscure due to the large margin of error in the rates reported by mostly small, single-center studies. Moreover, the functional and hemodynamic changes corresponding to early, possibly reversible stages of CTEPH, have not been systematically investigated. The ongoing Follow-Up after acute pulmonary embolism (FOCUS) study will prospectively enroll and systematically follow, over a 2-year period and with a standardized comprehensive program of clinical, echocardiographic, functional and laboratory testing, a large multicenter prospective cohort of 1000 unselected patients (all-comers) with acute symptomatic PE. FOCUS will possess adequate power to provide answers to relevant remaining questions regarding the patients' long-term morbidity and mortality, and the temporal pattern of post-PE abnormalities. It will hopefully provide evidence for future guideline recommendations regarding the selection of patients for long-term follow-up after PE, the modalities which this follow-up should include, and the findings that should be interpreted as indicating progressive functional and hemodynamic post-PE impairment, or the development of CTEPH.
DOI:doi:10.1007/s11239-016-1415-7
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

DOI: https://doi.org/10.1007/s11239-016-1415-7
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Female
 Humans
 Male
 Prospective Studies
 Disease-Free Survival
 Quality of life
 Acute Disease
 Aftercare
 Chronic thromboembolic pulmonary hypertension
 Cohort study
 Follow-up
 Functional impairment
 Pulmonary embolism
 Pulmonary Embolism
 Survival Rate
K10plus-PPN:1566507952
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68202994   QR-Code
zum Seitenanfang