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Verfasst von:Jonas, Rahul A. [VerfasserIn]   i
 Jonas, Jost B. [VerfasserIn]   i
Titel:Optic disc
Titelzusatz:fovea angle : the Beijing Eye Study 2011
Verf.angabe:Rahul A. Jonas, Ya Xing Wang, Hua Yang, Jian Jun Li, Liang Xu, Songhomitra Panda-Jonas, Jost B. Jonas
E-Jahr:2015
Jahr:November 6, 2015
Umfang:10 S.
Fussnoten:Gesehen am 20.12.2017
Titel Quelle:Enthalten in: PLOS ONE
Ort Quelle:San Francisco, California, US : PLOS, 2006
Jahr Quelle:2015
Band/Heft Quelle:10(2015,11) Artikel-Nummer e0141771, 10 Seiten
ISSN Quelle:1932-6203
Abstract:Purpose To determine the optic disc-fovea angle (defined as angle between the horizontal and the line between the optic disc center and the fovea) and to assess its relationships with ocular and systemic parameters. Methods The population-based cross-sectional Beijing Eye Study 2011 included 3468 individuals. A detailed ophthalmic examination was carried out. Using fundus photographs, we measured the disc-fovea angle. Results Readable fundus photographs were available for 6043 eyes of 3052 (88.0%) individuals with a mean age of 63.6±9.3 years (range: 50-91 years) and a mean axial length of 23.2±1.0 mm (range: 18.96-28.87 mm). Mean disc-fovea angle was 7.76 ± 3.63° (median: 7.65°; range: -6.3° to 28.9°). The mean inter-eye difference was 4.01 ± 2.94° (median: 3.49°; range: 0.00-22.3°). In multivariate analysis, larger disc-fovea angle was associated (regression coefficient r2: 0.08) with older age (P = 0.009; standardized regression coefficient beta: 0.05), thinner RNFL in the nasal superior sector (P<0.001; beta: -0.17), superior sector (P<0.001; beta: -0.10) and temporal superior sector (P<0.001; beta: -0.11) and thicker RNFL in the inferior sector (P<001; beta: 0.13), nasal inferior sector (P<001; beta: 0.13) and nasal sector (P = 0.007; beta: 0.06), higher prevalence of retinal vein occlusion (P = 0.02; beta: 0.04), and with larger cylindrical refractive error (P = 0.04; beta: 0.04). Conclusions The optic disc-fovea angle markedly influences the regional distribution of the RNFL thickness pattern. The disc-fovea angle may routinely be taken into account in the morphological glaucoma diagnosis and in the assessment of structure-function relationship in optic nerve diseases. Future studies may address potential associations between a larger disc-fovea angle and retinal vein occlusions and between the disc-fovea angle and the neuroretinal rim shape.
DOI:doi:10.1371/journal.pone.0141771
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: http://dx.doi.org/10.1371/journal.pone.0141771
 kostenfrei: Volltext: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141771
 DOI: https://doi.org/10.1371/journal.pone.0141771
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Eyes
 Fovea centralis
 Glaucoma
 Nerve fibers
 Optic disc
 Optic nerve
 Retinal degeneration
 Retinal vessels
K10plus-PPN:1566597005
Verknüpfungen:→ Zeitschrift

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