Association strength of three adiposity measures with autonomic nervous system function in apparently healthy employees

• Verfasst von: Koenig, John [VerfasserIn]
• Verfasst von: Sonntag, Diana [VerfasserIn]
• Verfasst von: Fischer, Joachim E. [VerfasserIn]
• Titel: Association strength of three adiposity measures with autonomic nervous system function in apparently healthy employees
• Verf.angabe: J. Koenig, B.G. Windham, L. Ferrucci, D. Sonntag, J.E. Fischer, J.F. Thayer, M.N. Jarczok
• E-Jahr: 2015
• Jahr: November 2015
• Umfang: 4 S.
• Fussnoten: Gesehen am 21.12.2017
• Titel Quelle: Enthalten in: The journal of nutrition, health & aging
• Ort Quelle: Paris : Springer, 2004
• Jahr Quelle: 2015
• Band/Heft Quelle: 19(2015), 9, Seite 879-882
• ISSN Quelle: 1760-4788
• DOI: doi:10.1007/s12603-015-0508-x
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 156663475X

Abstract

ObjectivesTo investigate the association of different measures of central (abdominal) and overall adiposity with autonomic nervous system (ANS) function, indexed by heart rate variability (HRV), in apparently healthy human adults.Design and MeasurementsCross-sectional data of 8,538 participants (20% female, age: 41 ± 11 years, body mass index (BMI): 24 ± 4 kg/m2, waist circumference (WC): 91 ± 12 cm, waist-to-height ratio (WHtR): 0.45 ± 0.08) were available for analysis.ResultsAll measures of adiposity were inversely correlated with vagally-mediated HRV indexed by RMSSD (all p<0.001). Strongest associations were found with WC and RMSSD (r = -0.29). Associations were stronger in males (WC r = -0.32) than in females (WC r = -0.23). Partial correlations revealed the same pattern for RMSSD (WC all pcc = -0.12 p<0.001; WC male pcc = -0.14 p<0.001; WC female pcc = -0.06 p<0.05). Correlation strength of BMI and WHtR with RMSSD were similar and significantly weaker compared to WC (p <.001) in unadjusted analysis. Overall, nonparametric Kendall’s tb led to the same conclusions.ConclusionThe present data supports previous findings, that HRV is related to measures of adiposity in healthy individuals. In line with previous research, we found that WC is more strongly related to measures of HRV, indicating that WC best captures adiposity related risk.