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Verfasst von:Kähler, Georg [VerfasserIn]   i
 Dutenhöfner, Christina [VerfasserIn]   i
 Magdeburg, Richard [VerfasserIn]   i
Titel:Endoscopic application of polysaccharide powder for hemostasis in anticoagulated pigs (with video)
Verf.angabe:Georg Kaehler, MD, Christina Dutenhoefner, Richard Magdeburg, MD
E-Jahr:2015
Jahr:July 2015
Umfang:3 S.
Fussnoten:Gesehen am 24.01.2018
Titel Quelle:Enthalten in: Gastrointestinal endoscopy
Ort Quelle:New York, NY : Elsevier, 1971
Jahr Quelle:2015
Band/Heft Quelle:82(2015), 1, Seite 161-163
ISSN Quelle:1097-6779
Abstract:Background: Acute GI bleeding remains a clinical problem of daily importance. Increasing numbers of patients with compromised coagulation challenge the established methods of endoscopic hemostasis. Therefore, new powders for the treatment of GI bleeding have been developed. Objective: To clarify the efficacy of a newly available anticoagulant powder in stopping hemorrhage. Design: A randomized prospective comparative study regarding the potential of an endoscopically applicable polysaccharide powder in pigs receiving antithrombotic medication. Setting: A professional veterinary animal laboratory. Patients: Twenty-two pigs were anticoagulated with heparin (n = 8), aspirin (n = 8), or no antithrombotic medication (n = 6), in a randomized order. Interventions: A bleeding ulcer with continuous bleeding (Forrest I b) was established in the stomach. Endoscopic hemostasis was performed using the powder. Main Outcome Measurements: Time to hemostasis and the amount of powder used were recorded. Follow-up occurred for 3 days, final hemoglobin measurement, followed by autopsy with control for post-interventional bleeding. Results: Endoscopic hemostasis was successful in all cases. Post-interventional bleeding was not recorded. Limitations: Animal study, artificial superficial bleeding source. Conclusion: Polysaccharide powder is able to stop active bleeding from Forrest I b lesions in pigs receiving antithrombotic therapy.
DOI:doi:10.1016/j.gie.2015.02.030
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1016/j.gie.2015.02.030
 Volltext: http://www.sciencedirect.com/science/article/pii/S001651071500156X
 DOI: https://doi.org/10.1016/j.gie.2015.02.030
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1567552536
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