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| Verfasst von: | Westhauser, Fabian [VerfasserIn]  |
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| | Weis, Christian [VerfasserIn] |
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| | Prokscha, Matthäus [VerfasserIn] |
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| | Xiao, Kai [VerfasserIn] |
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| | Kneser, Ulrich [VerfasserIn] |
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| | Kauczor, Hans-Ulrich [VerfasserIn] |
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| | Schmidmaier, Gerhard [VerfasserIn] |
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| | Moghaddam-Alvandi, Arash [VerfasserIn] |
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| Titel: | Three-dimensional polymer coated 45S5-type bioactive glass scaffolds seeded with human mesenchymal stem cells show bone formation in vivo |
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| Verf.angabe: | Fabian Westhauser, Christian Weis, Matthäus Prokscha, Leonie A. Bittrich, Wei Li, Kai Xiao, Ulrich Kneser, Hans-Ulrich Kauczor, Gerhard Schmidmaier, Aldo R. Boccaccini, Arash Moghaddam |
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| E-Jahr: | 2016 |
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| Jahr: | 7 June 2016 |
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| Umfang: | 7 S. |
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| Fussnoten: | Gesehen am 19.02.2018 |
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| Titel Quelle: | Enthalten in: Journal of materials science / Materials in medicine |
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| Ort Quelle: | Dordrecht : Springer Science + Business Media B.V, 1990 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 27(2016), 7, Seite 119 |
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| ISSN Quelle: | 1573-4838 |
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| Abstract: | 45S5-type bioactive glasses are a promising alternative to established substitutes for the treatment of bone defects. Because the three-dimensional (3D) structure of bone substitutes is crucial for bone ingrowth and formation, we evaluated the osteoinductive properties of different polymer coated 3D-45S5 bioactive glass (BG) scaffolds seeded with human mesenchymal stem cells (hMSC) in vivo. BG scaffolds coated with gelatin, cross-linked gelatin, and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) were seeded with hMSC prior to implantation into severe combined immunodeficiency mice. Newly formed bone was evaluated with histomorphometry and micro-computed tomography. Bone formation was detectable in all groups, whereas the gelatin-coated BG scaffolds showed the best results and should be considered in further studies.Graphical Abstract Open image in new window |
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| DOI: | doi:10.1007/s10856-016-5732-3 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: http://dx.doi.org/10.1007/s10856-016-5732-3 |
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| | Volltext: https://link.springer.com/article/10.1007/s10856-016-5732-3 |
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| | DOI: https://doi.org/10.1007/s10856-016-5732-3 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1569986770 |
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| Verknüpfungen: | → Zeitschrift |
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Three-dimensional polymer coated 45S5-type bioactive glass scaffolds seeded with human mesenchymal stem cells show bone formation in vivo / Westhauser, Fabian [VerfasserIn]; 7 June 2016 (Online-Ressource)
