Prognostic significance of pulsatile tinnitus in cervical artery dissection

• Verfasst von: Kellert, Lars [VerfasserIn]
• Verfasst von: Kloss, Manja [VerfasserIn]
• Verfasst von: Grond-Ginsbach, Caspar [VerfasserIn]
• Titel: Prognostic significance of pulsatile tinnitus in cervical artery dissection
• Verf.angabe: L. Kellert, M. Kloss, A. Pezzini, S. Debette, D. Leys, V. Caso, V.N. Thijs, A. Bersano, E. Touzé, T. Tatlisumak, C. Traenka, P.A. Lyrer, S.T. Engelter, T.M. Metso and C. Grond-Ginsbach for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study group
• E-Jahr: 2016
• Jahr: 1 March 2016
• Umfang: 5 S.
• Teil: volume:23
• Teil: year:2016
• Teil: number:7
• Teil: pages:1183-1187
• Teil: extent:5
• Fussnoten: Gesehen am 09.03.2018
• Titel Quelle: Enthalten in: European journal of neurology
• Ort Quelle: Oxford [u.a.] : Wiley-Blackwell, 1994
• Jahr Quelle: 2016
• Band/Heft Quelle: 23(2016), 7, Seite 1183-1187
• ISSN Quelle: 1468-1331
• DOI: doi:10.1111/ene.13031
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: acute ischaemic stroke
• Sach-SW: cervical artery dissection
• Sach-SW: outcome
• Sach-SW: pulsatile tinnitus
• K10plus-PPN: 1570683573

Abstract

Background and purpose: Our aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. Methods: All CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The presence of PT was systematically assessed using a standardized questionnaire. Stroke severity at admission was defined according to the National Institutes of Health Stroke Scale (NIHSS). Excellent outcome after 3 months was defined as a modified Rankin Scale of 0-1. Results: Sixty-three of 778 patients (8.1%) reported PT. PT+ patients presented less often with ischaemic stroke (41.3% vs. 63.9%, P < 0.001), more often with dissection in the internal carotid artery (85.7% vs. 64.2%, P = 0.001), less often with vessel occlusion (19.0% vs. 34.1%, P = 0.017) and more often with excellent outcome at 3 months (92.1% vs. 75.4%, P = 0.002). Logistic regression analysis identified PT as an independent predictor of excellent outcome after 3 months [odds ratio (OR) 3.96, 95% confidence interval (CI) 1.22-12.87] adjusted to significant outcome predictors NIHSS on admission (OR 0.82, 95% CI 0.79-0.86), Horner syndrome (OR 1.95, 95% CI 1.16-3.29) and vessel occlusion (OR 0.62, 95% CI 0.40-0.94) and to non-significant predictors age, sex, pain and location of CeAD. Conclusion: The presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome.